Systematic Review Search Research Articles

Keywords are missing: Insights from the publication keywords, abstracts and titles of an environment and human health research group

Inequalities within academia – and the research outputs of academic – are a widely acknowledged problem. This results in the reproduction of knowledge gaps within academic praxis. The current study presents a case study from an environment and human health research group, looking at the extent to which the research outputs mirror the wider knowledge gaps in the field. We use systematic review search methods to obtain publications for an environment and health research group since 2010. We use a combination of EndNote and VosViewer to analyse the frequency of key words and concepts in the titles, abstracts and keywords of these publications. We retrieved a total of 950 publications between 2010 and 2022. We find significant gaps with respect to key concepts appearing in the titles, abstracts and keywords of publications. We find that terms such as ‘colonisation’ and ‘racism’ are not mentioned at all. We reflect on the production process of academic research with respect to reproducing blind spots within environment and human health research. We discuss our results in the context of calls to make academic research more inclusive.

Factors Influencing The Implementation Of Health Service Quality Governance In Puskesmas: Systematic Review

Puskesmas is a health service facility that organizes public health efforts and individual health efforts at the first level, by prioritizing promotive and preventive efforts in their working areas. Puskesmas as health service providers for the community must provide excellent service that meets community expectations. Puskesmas need effective quality governance, service performance, service procedures, and resources used to provide primary services as efficiently as possible. Service quality is an important factor that refers to the level of service perfection. Efforts to guarantee the quality of puskesmas are carried out through an accreditation survey which is carried out every 3 years. This study aims to look at the factors that influence the quality of health services at puskesmas from various literatures. To collect and synthesize previous information, this study used a Systematic Literature Review search approach with the PRISMA method, using databases related to medical and academic topics, media publications, Google Scholar. Factors that influence the implementation of health service quality governance at the puskesmas consist of structural factors such as physical facilities, human resources, the leadership role of the head of the puskesmas, access to services, facilities and infrastructure, budget, medical devices, and other facilities, process factors consist of the PDCA method (Planning, Doing, Checking, Actuating), as well as the outcome factors in the form of success on the level of service and degree of public health. The availability of resources, the implementation process carried out by the puskesmas has an impact on the quality of health services provided, as well as having an impact on the output achievements, and the accreditation results of the puskesmas

Errors to avoid when searching for studies for systematic reviews: A guide for nurse researchers

Systematic reviews aim to provide reliable answers to research questions by identifying and synthesising the available evidence using rigorous methods. This makes systematic reviews a cornerstone of evidence-based practice in healthcare settings. However, despite the avowed aim and importance of systematic reviews, studies have shown that they often include serious flaws, including in the search for studies. In this article, some commonly seen errors in systematic review search strategies are described with the intention of alerting nurse researchers who are planning a systematic review to what should be avoided. These include errors relating to bibliographic databases and supplementary searches, including database selection, free-text searching, controlled vocabulary and structural errors. The paper is framed within the context of older people nursing but has relevance to nurse researchers more widely.

Research Perspectives in Collaborative Assembly: A Review

In recent years, the emergence of Industry 4.0 technologies has introduced manufacturing disruptions that necessitate the development of accompanying socio-technical solutions. There is growing interest for manufacturing enterprises to embrace the drivers of the Smart Industry paradigm. Among these drivers, human–robot physical co-manipulation of objects has gained significant interest in the literature on assembly operations. Motivated by the requirement for human dyads between the human and the robot counterpart, this study investigates recent literature on the implementation methods of human–robot collaborative assembly scenarios. Using a combination of strings, the researchers performed a systematic review search, sourcing 451 publications from various databases (Science Direct (253), IEEE Xplore (49), Emerald (32), PudMed (21) and SpringerLink (96)). A coding assignment in Eppi-Reviewer helped screen the literature based on ‘exclude’ and ‘include’ criteria. The final number of full-text publications considered in this literature review is 118 peer-reviewed research articles published up until September 2022. The findings anticipate that research publications in the fields of human–robot collaborative assembly will continue to grow. Understanding and modeling the human interaction and behavior in robot co-assembly is crucial to the development of future sustainable smart factories. Machine vision and digital twins modeling begin to emerge as promising interfaces for the evaluation of tasks distribution strategies for mitigating the actual human ergonomic and safety risks in collaborative assembly solutions design.

Emergency department crowding: an overview of reviews describing measures causes, and harms.

Crowding in Emergency Departments (EDs) has emerged as a global public health crisis. Current literature has identified causes and the potential harms of crowding in recent years. The way crowding is measured has also been the source of emerging literature and debate. We aimed to synthesize the current literature of the causes, harms, and measures of crowding in emergency departments around the world. The review is guided by the current PRIOR statement, and involved Pubmed, Medline, and Embase searches for eligible systematic reviews. A risk of bias and quality assessment were performed for each review, and the results were synthesized into a narrative overview. A total of 13 systematic reviews were identified, each targeting the measures, causes, and harms of crowding in global emergency departments. Key among the results is that the measures of crowding were heterogeneous, even in geographically proximate areas, and that temporal measures are being utilized more frequently. It was identified that many measures are associated with crowding, and the literature would benefit from standardization of these metrics to promote improvement efforts and the generalization of research conclusions. The major causes of crowding were grouped into patient, staff, and system-level factors; with the most important factor identified as outpatient boarding. The harms of crowding, impacting patients, healthcare staff, and healthcare spending, highlight the importance of addressing crowding. This overview was intended to synthesize the current literature on crowding for relevant stakeholders, to assist with advocacy and solution-based decision making.

Current aspects on the antipsychotic treatment of older people with schizophrenia spectrum disorders

From ageriatric perspective, the use of antipsychotic drugs (AP) is associated with significant risks in addition to their known effects. These include unfavorable interactions with geriatric syndromes, such as immobility and risk of falling, and potentially increased mortality, at least in certain patient groups. With reference to this the current state of knowledge on treatment with AP in older people with schizophrenia spectrum disorders is summarized with afocus on the typical multimorbidity of geriatric patients. Narrative review with special consideration of guidelines and consensus papers from German speaking countries and aPubMed-supported literature search for current systematic reviews and meta-analyses. Antipsychotic agents are an essential part of acomprehensive treatment concept for schizophrenia with well-documented evidence. In geriatric patients adaptations under gerontopharmacological aspects are necessary. Asufficient data basis for evidence-based recommendations for the treatment of multimorbid and frail geriatric patients does not exist. An effective and as safe as possible treatment with AP requires acareful risk-benefit assessment, combined with an individual adaptation regarding the substance applied, dose and treatment duration in an interdisciplinary/multiprofessional context.

Topical ketotifen treatment for allergic conjunctivitis: a systematic review and Meta-analysis.

To assess the efficacy of ketotifen in treating allergic conjunctivitis. A systematic search of systematic reviews and Meta-analyses was conducted on the PubMed and Web Science of Science until October 2021 to address this knowledge gap. Mean difference with 95%CI and P values were used to assess the efficacy of ketotifen. The heterogeneity (I 2) was used to evaluate the impact of heterogeneity. Eight randomized controlled trials (RCTs) involving 1589 patients were included in this Meta-analysis. The results revealed that after treating with ketotifen, itching (MD=-0.91, 95%CI: -1.63 to -0.20, I 2=94%, P=0.01), tearing (MD=-0.40, 95%CI: -0.61 to -0.18, I 2=75%, P=0.0003) and total signs and symptoms (MD=-0.85, 95%CI: -1.12 to -0.58, I 2=0, P<0.00001) showed better benefit effect compared to the placebo group. Topical ketotifen is an effective treatment for patients with allergic conjunctivitis.

Identification of biomarkers for vascular dementia: a literature review

SUMMARYAlzheimer's disease and vascular dementia are the two most common types of dementia. It becomes difficult to distinguish between the two, especially when there are no specific genetic causes or vascular changes apparent. The aim of this review was to identify specific biomarkers supporting the diagnosis of vascular dementia by conducting a literature search for systematic reviews and observational studies. We found seven studies meeting our inclusion/exclusion criteria, and from these we identified four specific biomarkers supporting the diagnosis of vascular dementia: high levels of thyroid-stimulating hormone, lipoprotein(a), homocysteine and N-terminal prosomatostatin. However, the studies were small and a well-conducted study with larger populations is recommended to strengthen the evidence base.

The Effect of Psychological Interventions on Sexual and Marital Satisfaction: A Systematic Review and Meta-Analysis.

Sexual and marital satisfaction play an important role in the stability of couples' relationships, so it is necessary to take a proper approach to promote them. This study aimed to identify and categorize psychological interventions affecting sexual satisfaction and marital satisfaction of women in Iran. An electronic systematic review search was conducted using the Persian and English databases of SID, Embase, PubMed, Scopus, Web of Science, Medline, Cochran library, and Google Scholar motor engine until 2021 to identify all relevant clinical trials and experimental and quasi-experimental studies assessing the effect of psychological interventions on sexual and marital satisfaction. Totally, we retrieved 528 studies from the previously mentioned databases, of which, 38 met the eligibility criteria. The subgroup meta-analysis of 4 studies conducted showed that interventions based on individual consultations increase sexual satisfaction (MD: 2.94, 95% CI: -0.36 to 6.24, P= .23), (I 2 =30.83%). The subgroup meta-analysis of 10 studies conducted revealed that couple-based consultations increase marital satisfaction (MD: 5.93, 95% CI: -2.59 to 9.27, P=.95), (I 2 = 0%). The results of meta-analysis demonstrated the effect of counseling-based psychological interventions on increasing sexual and marital satisfaction of couples. However, further clinical trials are required before making a definitive conclusion.

Does breast oncoplastic surgery improve quality of life?

Breast Oncoplastic Surgery (OS) has established itself as a safe procedure associated with the treatment of breast cancer, but the term is broad, encompassing procedures associated with breast-conserving surgeries (BCS), conservative mastectomies and fat grafting. Surgeons believe that OS is associated with an increase in quality of life (QOL), but the diversity of QOL questionnaires and therapeutic modalities makes it difficult to assess from the patient's perspective. To answer this question, we performed a search for systematic reviews on QOL associated with different COM procedures, and in their absence, we selected case-control studies, discussing the main results. We observed that: (1) Patients undergoing BCS or breast reconstruction have improved QoL compared to those undergoing mastectomy; (2) In patients undergoing BCS, OS has not yet shown an improvement in QOL, a fact possibly influenced by patient selection bias; (3) In patients undergoing mastectomy with reconstruction, the QoL results are superior when the reconstruction is performed with autologous flaps and when the areola is preserved; (4) Prepectoral implants improves QOL in relation to subpectoral implant-based breast reconstruction; (5) ADM do not improves QOL; (6) In patients undergoing prophylactic mastectomy, satisfaction is high with the indication, but the patient must be informed about the potential complications associated with the procedure; (7) Satisfaction is high after performing fat grafting. It is observed that, in general, OS increases QOL, and when evaluating the procedures, any preservation or repair, or the use of autologous tissues, increases QOL, justifying OS.

Evidence and gap map report: Social and Behavior Change Communication (SBCC) interventions for strengthening HIV prevention and research among adolescent girls and young women (AGYW) in low- and middle-income countries (LMICs).

Evidence and gap map report: Social and Behavior Change Communication (SBCC) interventions for strengthening HIV prevention and research among adolescent girls and young women (AGYW) in low- and middle-income countries (LMICs).

Effects of pharmacotherapy on sleep-related outcomes in adults with chronic low back pain: A systematic review and meta-analysis of randomised controlled trials.

Adults with chronic low back pain (CLBP) suffer impaired sleep. Medications for CLBP can impact sleep which in turn may influence treatment outcomes. This systematic review and meta-analysis examined the effects of pharmacotherapy (any type) on sleep in adults with CLBP. In this systematic review and meta-analysis, we searched PubMed, CINAHL, SPORTDiscus, PsycINFO, EMBASE, and CENTRAL from inception to 10 July 2022. Randomised controlled trials that investigated the effects of pharmacotherapy on sleep in adults with CLBP were included. Manual citation search of relevant systematic reviews and included studies were also conducted. Mean change from baseline for sleep outcomes (e.g., sleep quality, total sleep time, wake after sleep onset) was the effect of interest. Pairwise inverse-variance random effect meta-analysis was performed to impute pooled estimates (Hedges' g or risk ratios). The Hartung-Knapp-Sidik-Jonkman method was used where there were ≤5 studies. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used for evaluating the certainty of evidence. This study was registered with PROSPERO (CRD42022309419). Assessment of 3959 records resulted in nine studies (n=2927) being included. Pharmacotherapy for CLBP management had a small, yet unlikely clinically significant, effect on improving sleep in adults with CLBP, when compared to placebo (g [95% CI]:-0.23 [-0.37,-0.09], p=.0009; I 2 =30.1%; n=1433; studies: n=8; GRADE: low). Notably, no eligible studies investigated the effect of sleep medications in this population, despite being within the scope of this review. Pharmacotherapy used to manage CLBP provided improvements in sleep in adults with CLBP. Given that these effects were small and unlikely clinically significant, clinicians could consider alternative treatments (e.g., non-pharmacological interventions) for managing sleep in adults with CLBP. However, low to very low certainty of evidence precluded strong conclusions. To improve certainty of evidence and confidence in the effect estimates, future research needs to use robust method to minimise bias. Additional research evaluating multiple sleep characteristics, using both validated objective and subjective measures, is also warranted to further investigate the influence of distinct sleep parameters. The Summer Research Scholarship from the Appleton Institute, Central Queensland University, Australia.

Проявления ВИЧ-инфекции в полости рта у пациентов в зависимости от содержания CD4+ Т-лимфоцитов в крови

Objective - analysis and generalization of the available data on the manifestations of human immunodeficiency virus in the oral cavity depending on the number of CD4+ T-lymphocytes in the blood. Materials and methods. A search of clinical studies, systematic reviews, and online meta-analyses was conducted from 2004-2023 in the PubMed, Elsiever, Scopus, Cochrane, and Elibrary databases, which described oral manifestations of HIV infection as a function of CD4+ T-lymphocyte count. Results. Pseudomembranous candidiasis, hairy leukoplakia, Kaposi's sarcoma, and non-Hodgkin's lymphoma develop against a background of severe immunodeficiency when the CD4+ T-lymphocyte count is &lt;200 cells/μL blood. Kaposi's sarcoma also develops in people with a high CD8+ T-lymphocyte count (&gt;1000 cells/μL of blood) or with a low CD4+ to CD8+ ratio (CD4+:CD8+ ≤0.5). Non-Hodgkin's lymphoma develops not only with CD4+ T-cells &lt;200/μL, but also with a high number of CD8+ T-cells (≥2000 cells/μL of blood). Specific periodontal disease develops with moderate to severe immunodeficiency (CD4+ T-cells 200-500 cells/μL of blood). Necrotic ulcerative gingivitis is more often seen in severe immunodeficiency (CD4+ T-lymphocytes &lt;200 cells/μL). Conclusion. The development of pseudomembranous candidiasis (p&lt;0,05), "hairy" leukoplakia (p&lt;0,01), Kaposi sarcoma (p&lt;0,0001) statistically significantly correlates with CD4+ T-lymphocyte count &lt;200 cells/μl blood. In addition, the development of Kaposi's sarcoma, in addition to the low number of CD4+ T-cells, is affected by a high number of CD8+ cytotoxic lymphocytes &gt;1000 cells/μL (p=0.0003) and a low CD4+:CD8+ ratio ≤0.5 (p&lt;0.0003), which is statistically significant.

Influence of Smoking Habits on the Efficacy of EGFR-TKI Therapy in Patients with Advanced NSCLC: A Systematic Review and Meta-Analysis

Background: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are considered as the first-line treatment for advanced EGFR mutation-positive non-small cell lung cancer (NSCLC). We aimed to analyze the efficacy of EGFR-TKIs treatment in patients with advanced NSCLC of different smoking habits. Methods: We conducted a search for meta-analyses and systematic reviews on the PubMed, MEDLINE, Embase, and the Cochrane Library to address this knowledge gap. Patients were divided into 2 groups: (1) experimental group: treated with EGFR-TKIs or EGFR-TKIs combined with chemotherapy, immunotherapy, antiangiogenesis, radiotherapy and (2) control group: treated with chemotherapy. Progressive-free survival (PFS) and total survival (OS) were adopted for evaluating the efficacy of EGFR-TKIs between experimental group and control group. Results: Eleven studies including 6760 patients were included in the meta-analysis. The results showed that smoking (including previous and current smoking) significantly reduces the PFS and OS in comparison to non-smoking group in the treatment of NSCLC with EGFR-TKIs. In addition, EGFR-TKIs combined with anti-vascular endothelial growth factor therapy can reduce the risk of disease progression in smokers. Conclusions: Our study indicated that smoking significantly reduced the PFS and OS in comparison to non-smoking group in the treatment of NSCLC with EGFR-TKIs.

Breath Malodor – A Review of the Fundamentals

Abstract Recently, there has been an increased self-awareness of halitosis post the COVID-19 pandemic due to the continuous wearing of masks. Oral malodor, often known as foul/bad breath, is a foul odor that arises from the oral cavity. Numerous etiologic factors cause breath malodor, of which tongue coating is the most common intraoral cause. Extra-oral etiology, such as lung infections, diabetes, and kidney diseases, also plays a significant role. Halitosis is caused by anaerobic bacteria producing volatile sulfur compounds subsequent to protein degradation in the mouth. Intraoral etiology is the most common cause that can be efficiently treated with proper oral hygiene, mechanical, and chemical plaque control methods. Extra-oral etiology requires referral to a medical specialist. However, psychological causes such as halitophobia necessitate consultation with a clinical psychologist. Persistent oral malodor has a negative impact on social interactions and decreases the oral health-related quality of life. A literature search of review articles, systematic reviews, and studies on halitosis, using the mesh terms etiology, diagnosis, and management, was carried out using PubMed and Google Scholar search engines. This review addresses the basic concepts of oral malodor, its causes, pathophysiology, and management.

FUTURO DOS MODELOS DE LINGUAGEM NOS CUIDADOS EM SAÚDE: O PAPEL DO CHATGPT

The field of medicine has always been at the forefront of technological innovation, constantly seeking new strategies to diagnose, treat, and prevent diseases. Guidelines for clinical practice to orientate medical teams regarding diagnosis, treatment, and prevention measures have increased over the years. The purpose is to gather the most medical knowledge to construct an orientation for practice. Evidence-based guidelines follow several main characteristics of a systematic review, including systematic and unbiased search, selection, and extraction of the source of evidence. In recent years, the rapid advancement of artificial intelligence has provided clinicians and patients with access to personalized, data-driven insights, support and new opportunities for healthcare professionals to improve patient outcomes, increase efficiency, and reduce costs. One of the most exciting developments in Artificial Intelligence has been the emergence of chatbots. A chatbot is a computer program used to simulate conversations with human users. Recently, OpenAI, a research organization focused on machine learning, developed ChatGPT, a large language model that generates human-like text. ChatGPT uses a type of AI known as a deep learning model. ChatGPT can quickly search and select pieces of evidence through numerous databases to provide answers to complex questions, reducing the time and effort required to research a particular topic manually. Consequently, language models can accelerate the creation of clinical practice guidelines. While there is no doubt that ChatGPT has the potential to revolutionize the way healthcare is delivered, it is essential to note that it should not be used as a substitute for human healthcare professionals. Instead, ChatGPT should be considered a tool that can be used to augment and support the work of healthcare professionals, helping them to provide better care to their patients.

How effective are psychological treatments for internet gaming disorder? An umbrella review

Behavioural addictions such as Internet addiction (IA) and, more specifically, Internet gaming disorder (IGD) or video game addiction, have increased their prevalence in recent years in the child and adolescent population. The aim of the present study was to review and synthesise the existing evidence on the effectiveness of psychological treatments for addressing this addiction, as well as to compare them with other types of treatment. To this end, an in-depth search for systematic reviews and meta-analyses was carried out across different databases (WOS, Scopus, PubmMed, Cochrane), inclusion and exclusion criteria were set, and guidelines for the search strategy were defined, as well as the study selection method. A total of 14 reviews and meta-analyses were reviewed. The results showed that cognitive behavioural therapy (CBT) was the most studied psychological treatment, consistently showing effectiveness in reducing the symptoms and severity of IA/IGD. Furthermore, CBT appeared to be more effective when combined with other types of treatment such as pharmacological treatment. It is concluded that there is a need to investigate the effectiveness of psychological treatments for IA/IGD separately in order to provide appropriate interventions to reduce the severity of addiction and improve the quality of life and well-being of children and adolescents.

Abstract A131: The effective of mHealth intervention on hepatitis B virus screening among Asian Americans: A scoping review

Abstract Introduction. Hepatitis B virus (HBV) is one of the major health threats causing cancer. Asian Americans are especially vulnerable to HBV infection risk compared to other racial/ethnic groups in America. New mHealth interventions have promising potential to save lives by increasing HBV screening among racial/ethnic minority groups, but its scope, range, and uptake among Asian Americans are not clear. This study aims to scope the literature describing the research of mHealth interventions on HBV screening among Asian Americans. Methods. A scoping systematic review search is conducted in PubMed and Embase. Eligible studies focus on Asian Americans aged 18 years or older who have participated in an mHealth Hepatitis B screening. All types of mHealth interventions on HBV are relevant (e.g., health apps and text messages). Studies not published in the English language will be excluded. Results. A review protocol is developed. Next. We will covert our search strategy to Embase, Medline, and other databases to get more records. At present, title and abstract screening are under development. After that, full-text screening, data extraction, data management, quality assessment, and data synthesis and analysis will be conducted. Initial results will be discussed. Potential impact. The results of this scoping and systematic review could improve our understanding of mHealth HBV screening use and uptake among Asian Americans and inform the development of a future intervention to encourage mHealth HBV screening for this patient population. In the long run, it could encourage the development of a future tailored mHealth intervention to facilitate the HBV screening uptake among Asian Americans Citation Format: Di Zhu, Yarra Zisman-Ilani, Stephanie Roth, Lin Zhu, Grace X. Ma. The effective of mHealth intervention on hepatitis B virus screening among Asian Americans: A scoping review [abstract]. In: Proceedings of the 15th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2022 Sep 16-19; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr A131.

A Systematic Review of Tissue Engineering of a Total Artificial Heart: Focus on Perfusion Decellularization

Introduction: A leading cause of death worldwide is heart disease, and in the United States alone, 6.2 million individuals live with heart failure. The recent ability to recreate the vascular network of cardiac Extracellular Matrix (ECM) suggests the feasibility of engineering whole heart constructs. Tissue engineering method such as perfusion decellularization allows for effective removal of nearly all cellular composition of a heart while maintaining the native mechanical integrity of the scaffold. This scaffold can be reseeded with stem cells in the hopes of generating a functional heart. The goal of this systematic review was to assess the various perfusion decellularization methods and its effects upon the biologic scaffold. Methodology: A comprehensive systematic literature review search was carried out through Pubmed, MEDLINE and Google Scholar using the search terms “whole heart decellularization”, “whole organ decellularization” and “perfusion decellularization”. The inclusion criteria for this research were as follows: scholarly or peer-reviewed studies, published within the last 20 years in the English language, and primary studies in which whole cardiac organ decellularization was performed. Chosen articles were those examining the various decellularization methods and its effects upon the biologic scaffold. Excluded were studies regarding heart valve decellularization, tissue decellularization, cardiac patch, tissue recellularization, articles in foreign languages, articles dated prior to 2001, literature reviews, systematic reviews, and duplicate articles. Results: Chemical agents such as acid and bases cause hydrolytic degradation of biomolecules which could reduce ECM strength and eliminate growth factors from the matrix. Compared to other detergents such as Triton X-100, sodium dodecyl sulfate yields a more complete removal of nuclear material. A combination of these various approaches has shown an increased efficacy of the decellularization process. The decellularization of a large solid organ such as the heart requires several sophisticated steps. Perfusion decellularization is achieved via anterograde or retrograde perfusion of the intrinsic vascular network of the heart by utilizing decellularizing agents (i.e., chemicals and/or enzymes). Hodgson et al., 2017 demonstrates a combined strategy in which the decellularization of porcine hearts is accomplished in 24 hours and results in 98% DNA removal with only 6 hours of detergent exposure. Conclusion: There have been significant advances to address the heart disease epidemic. A promising approach is perfusion decellularization which allows for complete DNA content removal while maintaining the ECM scaffold integrity. This scaffold is then re-cellularized with stem cells in the hopes of creating an artificial heart. There are several challenges that need to be surpassed before bio-artificial hearts can be used to replace in vivo function. Future research is directed towards optimizing types of cells and cell sources used to repopulate decellularized hearts, seeding strategies and bioreactor systems to provide in vitro conditions required for organ maturation.

Ethics in the professional practice of imaging specialists

Introduction: During professional practice, it is absolutely necessary that ethics and Imaging complement each other as fundamental sciences. Objective: Describe the role of ethics in Imaging for the proper development of professional practice. Methods: In June and July of 2023, an electronic search for publications and systematic literature reviews was conducted using Google Scholar and the electronic databases PubMed, Medline, and SciELO. The following descriptors were used: "ethics and medical ethics", "Imaging", and "ethics and Imaging". A total of 56 sources were reviewed in the databases mentioned above. Out of these, 31 bibliographic references were used.Results: Imaging specialists, like other healthcare professionals, must adhere to ethical duties that include respecting privacy, maintaining privileged communication, confidentiality, and obtaining informed consent. Professionals in the field often face ethical conflicts during their practice. Therefore, it is crucial that they are technically and scientifically prepared to handle such situations. This is especially important when dealing with medical-legal imaging and the ethical dilemmas that may arise. It is essential to pay close attention to the indication of imaging studies, particularly when they do not provide any benefit to the patient. Conclusions: Imaging specialists who are involved in patient care must adhere to ethical standards governing the practice of the profession