PurposeThe purpose of this study is to review the different facets associated with Industry 5.0 (I5.0) and propose a conceptual framework to boost the applicability of this novel technological cum social aspects within industrial organizations for improved organizational sustainability.Design/methodology/approachThis research work adopted a bibliometric analysis that encapsulates a quantitative set of tools for bibliometric and bibliographic information. This study uses the database of Scopus to acquire data related to different facets of I5.0. The study implies a different spectrum of terms to reach the final corpus of 91 articles related to I5.0. Furthermore, a conceptual define, measure, analyze, improve and control (DMAIC)-based framework based on different literature findings is proposed and validated based on the input of experts from different parts of the world.FindingsThe results indicate that I5.0 is still in its infancy. The wider applicability of I5.0 demands comprehensive theoretical knowledge of different facets of this new paradigm and the development of a framework to adopt it on a larger scale. Organizations that are in the race to adopt I5.0 face major challenges related to the digitization of processes along with well-defined cyber-physical systems and the lack of a dedicated framework to execute I5.0. Furthermore, the result also suggests that manufacturing industries are more ready to adopt I5.0 practices as compared to service industries, which can be attributed to well-defined technological measures available in manufacturing settings.Originality/valueTo the best of the authors’ knowledge, this is one of the first studies that explore different know-how and challenges and provides a holistic view of I5.0 by providing a systematic adoption framework.