Synthetic Glue Research Articles

Indications and results of pancreatic stump duct occlusion after duodenopancreatectomy.

Severe post-operative complications after pancreaticoduodenectomy (PD) are largely due to pancreatic fistula onset. The occlusion of the main pancreatic duct using synthetic glue may prevent these complications. Aim of this study is to describe this technique and to report short- and long-term results as well as the post-operative endocrine and exocrine insufficiency. Two hundred and four patients who underwent PD with occlusion of the main pancreatic duct in a period of 15years were retrospectively analyzed. Post-operative complications and their management were the main aim of the study with particular focus on pancreatic fistula incidence and its treatment. At 1-year follow-up endocrine and exocrine functions were analyzed. We observed a 54% pancreatic fistula incidence, most of which (77/204 patients) were a grade A fistula with little change in medical management. Twenty-eight patients developed a grade B fistula while only 2% of patients (5/204) developed a grade C fistula. Nine patients required re-operation, 5 of whom had a post-operative grade C fistula. Post-operative mortality was 3.4%. At 1-year follow-up, 31% of patients developed a post-operative diabetes while exocrine insufficiency was encountered in 88% of patients. The occlusion of the main pancreatic duct after PD can be considered a relatively safe and easy-to-perform procedure. It should be reserved to selected patients, especially in case of soft pancreatic texture and small pancreatic duct and in elderly patients with comorbidities, in whom pancreatic fistula-related complications could be life threatening.

Has your ancient stamp been regummed with synthetic glue? A FT-NIR and FT-Raman study

The potential of FT-NIR and FT-Raman spectroscopies to characterise the gum applied on the backside of ancient stamps was investigated for the first time. This represents a very critical issue for the collectors' market, since gum conditions heavily influence stamp quotations, and fraudulent application of synthetic gum onto damaged stamp backsides to increase their desirability is a well-documented practice. Spectral data were processed by exploratory pattern recognition tools. In particular, application of principal component analysis (PCA) revealed that both of the spectroscopic techniques provide information useful to characterise stamp gum. Examination of PCA loadings and their chemical interpretation confirmed the robustness of the outcomes. Fusion of FT-NIR and FT-Raman spectral data was performed, following both a low-level and a mid-level procedure. The results were critically compared with those obtained separately for the two spectroscopic techniques.

Laparoscopic sacrocolpopexy with a vaginal prosthetic adhesive

Study objectiveTo evaluate the efficacy and safety of vaginal prosthetic adhesive (VPA) during laparoscopic sacrocolpopexy. DesignRetrospective analysis of 35 first consecutive cases. SettingGynecology Surgery Unit, Bouchard Clinic, Marseille, France. PatientsThirty-five women (age range: 35–85 years; average 60.8 years) presenting a genital prolapse assessed by a Pelvic Organ Prolapse Quantification (POP-Q) Score (stage 2 to 4). ProceduresModified laparoscopic sacrocolpopexy using a synthetic glue (Ifabond™, Peters Surgical®) to fix the mesh to the vagina (anterior and posterior) and to the levator ani. Two non-absorbable knots are used to secure the anterior mesh to the isthmus and to the promontory. Measurements and main resultsThe average operating time was 68.4 minutes (45–115 min). No complications occurred during the procedure and early postoperative course. One patient (2.8%) experienced mesh exposure, and one patient (2.8%) experienced a subacute intestinal obstruction, which was resolved by a medical treatment. During a median follow-up at 13.2 months (range: 6–24.7 months), the surgical success rate (POP-Q<2) was 94.2% (two recurrences). The patient satisfaction rate was 87%. ConclusionsThe VPA during laparoscopic sacrocolpopexy seems to be safe and effective at short term. This new procedure due to adhesive opens up a new path for the widespread use of sacrocolpopexy and for reduced operating times, which is often one obstacle with the dissection in the development of this technique.

The use of cyanoacrylate sealant as simple mesh fixation in laparoscopic ventral hernia repair: a large animal evaluation.

The use of glue as mesh fixation in laparoscopic ventral hernia repair (LVHR) significantly reduces fixation associated morbidity. This experiment evaluates the intraperitoneal use of synthetic glue as single mesh fixation. A total of 21 sheep were operated using a hernia model with two fascial defects of 2 cm(2) at the linea alba. One week later two polypropylene meshes (Dynamesh®) were implanted laparoscopically, using cyanoacrylate glue (Ifabond®) or conventional fixation (Securestrap®). In half of the animals the fascial defect was closed before mesh placement. After 1 day (n = 6), 2 weeks (n = 8) and 6 months (n = 6), a second laparoscopy was performed at which hernia recurrence, mesh integration and adhesion formation were evaluated. After euthanasia, burst strength testing and histopathology were evaluated. One animal died due to intestinal incarceration. In 20 surviving animals, no hernias were diagnosed and mesh placement was satisfying. Adhesions could hardly be observed after 1 day but were omnipresent in both groups at 2 weeks and 6 months. Burst strength testing exceeded 100 N in all samples, independent of the fixation device used. Not after 1 day, but after 2 weeks the inflammatory cell response was significantly higher in the glue group. At 6 months minor inflammation was seen, as was foreign body reaction (FBR). Using a standardized biomechanical testing system, synthetic glue can be considered an effective fixation tool in LVHR. The possible tissue toxicity of cyanoacrylates does not lead to an increased FBR. No difference in burst strength was observed for closing or not closing the defect.

Cyanoacrylate Surgical Glue for Mesh Fixation in Laparoscopic Total Extraperitoneal Hernia Repair

In an attempt to find the ideal surgical technique for mesh fixation during laparoscopic total extraperitoneal inguinal hernia repair, we evaluate the use of a synthetic surgical glue (N-butyl-cyanoacrylate-Glubran 2) in an effort to reduce postoperative pain and the complications associated with the use of staples. We have prospectively evaluated 61 consecutive patients (73 hernias) with a minimum follow-up period of 18 months and an average of 29.7 months, without any significant complications present. The majority (59%) only required low dosages of painkillers during the first 24 hours after surgery and have not experienced any cases of chronic pain or recurring hernias in the time period described. On the basis of this initial experience, the use of the surgical glue used to repair inguinal hernias with the laparoscopic total extraperitoneal technique has been proved to be a simple and effective surgical method for mesh fixation.

ENERGY SAVING BY SOIL INSULATION IN GREENHOUSE FREESIA PRODUCTION

This paper describes attempts to find practical methods for mulching in Freesia to prevent evaporation from the soil. If mulching could insulate soil not only for temperature, but also for evaporation, more energy might be saved. Two experi-ments at commercial greenhouses were done to test soil insulation. The first experi-ment aimed to test materials and strategies. This experiment showed that a mulch of styromul bound together with synthetic glue or paper cellulose did not inhibit or harm the crop. In the second experiment soil was insulated using: Biofoam® (5 mm layer), Styromul (5 mm layer), Biofoam® glued together with synthetic glue (20 mm layer, Biofoam® glued together with organic glue (20 mm layer), styromul glued together with synthetic glue (20 mm layer) and an untreated control. Slightly increased evaporation using any mulch layer was measured. However, soil temperature was also higher because of soil heating resulting in higher evaporation of the soil. Net evaporation is calculated to have been decreased by 12% using 20 mm instead of 5 mm mulch, which is expected to result in energy saving of 11.1 MJ.m-2.yr-1 on humidity control, which is too low to make up for the cost. Soil insulation decreased temperature fluctuations. Increasing the thickness of the mulch increased temperature insulation, however the effect appeared to decrease rapidly with increasing layer thickness

Curative glubran 2 embolization of cerebral arteriovenous malformations patient selection and initial results.

The liquid embolic agents currently used for embolization of cerebral arteriovenous malformations are Onyx and NBCA. Glubran 2, a cyanoacrylate-based synthetic glue, has recently been applied for embolization of cerebral arteriovenous malformations (AVMs). We report the clinical results of selected cerebral AVMs treated with Glubran 2 targeting for curative embolization. Between October 2011 and March 2013, 31 patients with cerebral AVMs were selected for curative embolization with Glubran 2. There were 19 men and 12 women with a mean age of 32 years (range 4-65 years). Initial clinical presentation included hemorrhage in 28 and seizures in three patients. AVM location was frontal in eight patients, parietal in four, occipital in eight temporal in six, cerebellar in two and cerebellar vermis in three patients. Follow-up was performed clinically and with angiography examination at three to six months. Clinical outcomes were evaluated based on the modified Rankin Scale (mRS). A mean of 2.5 (range, 1-12) feeding pedicles were embolized per patient. Complete angiographic obliteration of AVM was achieved in 27 patients. A hemorrhagic complication was observed in one patient, an ischemic complication in one patient and technical complications in four patients. There was no procedure-related disabling neurological deficit or death at discharge. Additional gamma knife radiosurgery was performed in five patients, including one patient with recurrent AVM. All of the patients had favorable clinical outcomes at three to six month follow-up (mRS≤2). The curative embolization technique with Glubran 2 for selected cerebral AVMs achieved a high initial complete obliteration rate with an acceptable complication frequency.

A unique and unexplained ricochet leak post PCI – Successfully treated with intra-coronary glue

We herein describe a unique case of coronary artery perforation treated with covered stent with repeat cardiac tamponade resulting out of a fresh unexplained leak from a remote vessel (Ricochet) and successfully treated with intra-coronary injection of sterile synthetic glue, cyanoacrylate.

Medial Regeneration Using a Biodegradable Felt as a Scaffold Preserves Integrity and Compliance of a Canine Dissected Aorta

Repair of a dissected aorta involves reattaching the media with synthetic glue and/or reinforcement with nonbiodegradable felt. Late complications specific to each aspect of this procedure have been reported. We attempted to regenerate the media by using biodegradable felt. We created a canine model of descending thoracic aortic dissection and compared 4 modes of aortic repair: biodegradable polyglycolic acid (PGA) felt in the media; PGA with basic fibroblast growth factor (bFGF) in the media; PGA with bFGF in the media plus external reinforcement with expanded polytetrafluoroethylene; and primary suture closure of the dissected lumen (control). Repaired aortic stumps were quantitatively tested for suture pull-out strength. Failure force improved 4-fold in all 3 medial reinforcement groups compared with controls. Additionally, animals were kept alive for histological examination and compliance testing 6 months after repair. Compliance of the aortic wall at the anastomotic sites was not essentially affected in the long term except in the group with concomitant external reinforcement (55.9 ± 4.5% reduction; P<0.05). In this group, elastic fiber in the media and collagen fiber in the adventitia tended to diminish relative to the other groups. Regarding vessel density in the repaired false lumen, this external reinforced group had a significantly decreased number. Histological derangement was not observed in control or medial reinforcement groups. Basic FGF, applied with PGA in the dissected lumen, failed to yield additional modifications in this model. Medial reinforcement provides sufficient augmented strength for aortic surgical repair. Medial regeneration using biodegradable felt as a scaffold preserves histological integrity and compliance in the canine dissected aorta.

Conservation treatment and stabilization of the ninth-century Stuttgart Psalter

Abstract This article describes conservation of the ninth-century Stuttgart Psalter, Wurttembergische Landesbibliothek, which contains over 300 illuminations on parchment. Some of the illuminations were consolidated with a special brush and sturgeon glue. The spine of the manuscript was released from synthetic glue with Laponite. Two types of repair tissue were used, both of them protein-based, handmade and reproducible in terms of thickness and components. Some losses were filled with handmade goldbeater's skin. Losses due to corrosion of the copper green pigment occur throughout the manuscript; these parts were stabilized with reconstituted parchment with a thickness of 0.03mm (1.4g·m−2). This represents a refinement of existing techniques to create a much thinner sheet than is typically used. Because the hide powder had changed in quality over the years, the preparation procedure needed to be adapted. For highly valuable manuscripts with copper green corrosion, this lightweight reconstituted parchment ...

Flow field around side-by-side piers with and without a scour hole

The present study provides the experimental results of the flow pattern around two-circular piers positioned in side-by-side arrangement. The experiments were performed for two bed configurations (with and without a scour hole). Velocities were measured by an Acoustic Doppler Velocimeter (ADV). Flat bed and scour hole were frozen by synthetic glue to facilitate the performance of the experiments. The contours and distributions of the time-averaged velocity components, turbulence intensities, turbulence kinetic energy, and Reynolds stresses at different horizontal and vertical planes are presented. Streamlines and velocity vectors obtained from time-averaged velocity fields are used to show further flow features. Bed shear stresses at specific points around the piers are given. The results of power-spectra analysis are presented inside and outside the scour hole. It is shown that the horseshoe vortex is elongated further to the downstream of the gap between the two piers. The flow between the two piers is accelerated into the scour hole so that it influences the vertical and transverse deflections of the flow around and especially between the two piers. The maximum downflow was inside the scour hole near the base of the pier. Between the two piers, the magnitude of downflow and vertical turbulence intensity as well as turbulence kinetic energy are greater than that at the outer sides of the two piers. Bed shear stress has substantially large values between the two piers, as much as two times in comparison to the other sides of the piers. The flow pattern including the contracted flow and interference between the horseshoe vortices play an important role in the creation and formation of the greater scour depth between the two piers. The presence of scour hole changes the behavior of vortex shedding considerably. The present detailed measurements can also be used for the verification of numerical models.

Lichtenstein repair of inguinal hernia: fibrin glue or suture for mesh fixation?

First of all, we wish to thank Tripoloni and Schierano [1] for the attention they paid to our trial comparing fibrin glue versus suture for open tension-free Lichtenstein hernia repair [2]. We appreciate their interest in the details. We agree that the two groups may have included subgroups that could cause bias, but we have to remember that this was a prospective observational multicenter study. The study was not randomized or blinded and, for this reason, no formal power calculations were undertaken. This is what happens with observational studies (cohort studies) which, for this reason, reach the level of evidence 2B with grade of recommendation B. Nonetheless, they can provide interesting results or suggestions for clinical practice. In our study, fewer patients in the fibrin glue group reported pain, numbness, and discomfort compared with patients in the sutures group at 1 month, and this occurred until the third month, when all differences disappeared, with the exception of numbness, which continued to be more prevalent in the sutures group. Tripoloni and Schierano [1] noted that the difference in pain intensity in favor of fibrin glue is not clinically meaningful. We agree with this, but the fact remains statistically meaningful. Anyway, in the literature, comparisons among different techniques for hernia repair, i.e., open versus laparoscopic repair, are often based on little variation in terms of mild or mild moderate pain. In our study, the mean operating time was reduced by 9% in the fibrin glue group compared to the sutures group. Although this value is statistically meaningful, Tripoloni and Schierano [1] believe that 6 min for each procedure is of little practical importance. We wish to underline that our study included 16 centers with extensive experience in hernia surgery. In less expert hands, i.e., residents and young surgeons, this saving of time is probably greater, with economic advantages. Of greater importance seems to be the remark on the risk of recurrence and that fibrin glue should expose to higher recurrence risk if compared to the sutures group. Actually, the two recurrences in our study occurred in the first group and in patients with direct hernias (type M) (more numerous in the fibrin glue group for the lack of stratification). We revised the files of both patients that were re-operated for recurrence. In both cases, a mesh of inadequate size was used. Both hernias recurred distally to the mesh, close to the pubic tubercle, type M1. The letter by Tripoloni and Schierano [1] provides us the opportunity to stress the importance of using a mesh of sufficient size to overlap the pubic tubercle, as requested also when a tension-free suture Lichtenstein repair for direct hernia is performed. With this solution, the difference in the recurrence rate between the two techniques nullifies. We, together with all the co-workers in our study, continue to believe that, in the future, the use of fibrin or synthetic glue for mesh fixation or self-gripping meshes will probably replace sutures in groin hernia repair.

A self-adhering mesh for inguinal hernia repair: preliminary results of a prospective, multicenter study

Prosthetic reinforcement is the gold standard treatment for inguinal hernia and reduces the risk of recurrence. Yet up to one-third of patients complain of post-surgical pain due to irritation and inflammation caused by the mesh and the fixation materials. Of these patients, 3-4% will experience severe and disabling chronic pain. We performed a prospective multicenter clinical study of a self-adhering prosthesis, consisting of a lightweight polypropylene mesh (40g/m²) coated on each side with synthetic glue, to evaluate early postoperative complications and patient outcomes. Between August 2008 and June 2010, 186 patients underwent hernia repair using the Lichtenstein technique and the self-adhering prosthesis. Primary endpoints were the frequency of disabling complications and quality of life (QoL) at 3-month follow-up. Pain, numbness, and groin discomfort were evaluated pre- and postoperatively (1week, 1 and 3months) using a visual analogue scale (VAS). Patients' pre- and postoperative QoL were measured using the SF12 questionnaire. Secondary endpoints were number of complications and recurrence rate, use of analgesic drugs, length of hospital stay, delay to return to normal activities, and patient satisfaction. The quality of the self-adhering mesh and its clinical utility were also evaluated by the participating surgeons. A total of 186 patients were enrolled and followed for at least 3months after inguinal hernia repair. A total of 174 (95%) primary hernias and 12 (5%) recurrent hernias were treated. There were no intraoperative complications, no recurrences, and no repeat interventions performed during the study. The post-surgical complication rate was 4.5%. The mean delay to recover normal physical activity was 4days. For the primary endpoint of pain, a VAS of zero was reported by 93/184 (50.5%) patients at 1week, 130/171 (76.0%) patients at 1month and 119/132 (90.2%) patients at 3months' follow-up (P<0.0001). The postoperative SF12 scores showed a significant improvement in patient QoL following surgery (P<0.0001). Adhesix( ® ) self-adhering mesh for prosthetic reinforcement following inguinal hernia repair is atraumatic and associated with infrequent post-surgical complications or pain, a rapid recovery rate, and a high patient-reported QoL. A longer follow-up is underway to assess the frequency of post-surgical recurrence.

Die Rolle der Embolisation bei venösen Malformationen

The treatment of congenital, vascular malformations is a challenge for physicians and patients. Although different therapeutic options have been described to date, their individual relevance has still to be defined. Â METHODS: We performed a retrospective study of 61 patients with a venous malformation (VM, mean age 22 years), who were referred to our depart-ment during the last 5 years. The size of the VM was larger than 5 cm in 41 patients (66 %). The lower extremities were involved in 45 cases (73 %). The most frequent clinical manifestations were recurrent swelling (80 %), pain (63 %), varicosis (60 %) and thrombophlebitis (39 %). MR angiography with venous sequences was always performed before treatment. Depending on the localisation and the extension of the VM, different techniques of embolisation were selected: foam sclerotherapy or application of synthetic glue by direct punction, coiling of pelvic veins or arterial embolisation with glue. 42 patients (69 %) underwent a procedure because of the complaints or the extension of the VM. An embolisation was performed in 25 patients with 65 interventional sessions. The most frequent technique was foam sclerotherapy (45 ×), followed by glue injection (13 ×), pelvic -venous coiling (6 ×) and arterial embolisation with glue (1 ×). Fifteen patients (60 %) reported a very good and 8 patients a marked improvement (32 %). In two cases there was no change of the complaints. The postinterventional complications were severe pain (n = 3) and skin/fat necrosis at the toe of one patient. The embolisation of venous malformations is an effective therapeutic tool. Different techniques can be used to address specific localisations and morphological patterns. The com-plication rate is very low when a step-by-step -approach is used, so that a repeat intervention is feasible. However, a more specific documentation of the post-interventional changes of the VM is needed before a general recommendation can be given.

Protection of intestinal anastomosis with biological glues: an experimental randomized controlled trial

The aim of the study was to compare the degree of healing and air tightness of hand-sewn colonic anastomoses provided by different biological glues. Thirty colonic anastomoses were fashioned in ten rabbits, at 5, 10, 15 cm from the ileocecal valve, with 4/0 PDS running sutures. Each suture was randomized to treatment with fibrin sealant (Tissucol®), a synthetic glue (Coseal®), or nothing (control). After 15 days, the rabbits were killed and the anastomoses examined for their integrity and resistance to bursting. The van der Hamm scale was used to evaluate postoperative adhesions. A blind histological evaluation of the newly formed tissue was made (Ehrlich-Hunt scale). Two rabbits developed an intraabdominal abscess, one in the control anastomosis group without glue. Postoperative adhesions were present in all animals. Median anastomosis bursting pressures were 0.9 atm in all three groups: Tissucol, Coseal, and control. Pressure values were 0.9, 1.0, and 0.9 atm in the three different proximodistal sites, respectively. A trend toward an increased resistance was observed in the glued anastomosis, although this was not significant. Lymphocyte infiltration, fibroblast activity, blood vessel density, and collagen deposition were lower in controls. Anastomoses treated with Tissucol had the highest lymphocyte infiltration level. The Coseal group developed the highest rates of fibroblast activity, collagen deposition, and blood vessel neogenesis. The use of biological glues did not result in a statistically significantly increased bursting resistance. Histological evaluation demonstrated more intense tissue neoformation in the glue groups, particularly in the Coseal group. The role of biological glues in decreasing the leakage rate of intestinal anastomoses is uncertain, and larger trials using different protective agents are warranted.

Efficacy of synthetic glue treatment of high crypoglandular fistula-in-ano

In France, seton drainage followed by fistulotomy is currently the standard treatment for high cryptoglandular fistula-in-ano. Biological or synthetic glues, such as Glubran(®)2, have been recently proposed for sealing the fistula tract. The purpose of this study is to determine the healing rate with glubran2 and to assess the functional outcome after cure of fistula-in-ano. From July 2006 to July 2008, 34patients (20males; median age 48.5years, range 22-55years) with high cryptoglandular anal fistulas were treated with glubran2. Patients were seen for physical examination at 1, 3 and 6months, then interviewed by telephone at 1 and 2years, and in September 2009. The Fecal incontinence severity index (FISI) score was used to assess continence. The healing rate at 1month was 67.6% (23patients); the fistula failed to heal in 11patients. All 23patients with a healed fistula remained recurrence-free, with no continence disorders noted, during the median 34-month follow-up period (range 21-43months). One patient was lost to follow-up after 6months. Glubran2 provides an effective treatment for high fistula-in-ano, with no change in continence. In future, a randomized comparison of this agent with fibrin glues should be useful.

A Novel Approach for Reinforcing the Pancreatic Remnant in Laparoscopic Distal Pancreatectomy

The major postoperative complication after open and laparoscopic distal pancreatectomy is pancreatic fistula. Different operative techniques have been tested to minimize this unpleasant complication. We evaluated a new technique for pancreatic stump reinforcement with synthetic glue after laparoscopic distal pancreatectomy. Ten female domestic pigs were divided into 2 groups; in group A (n=5), the pancreas was transected using an EndoGIA stapler, whereas in group B (n=5), the pancreas was transected using a Ligasure device and the pancreatic stump was reinforced with a hydrogel sealant. The clinical postoperative course was uneventful in all the cases. No differences were observed in pancreatic remnant healing between the groups, and only minor microscopic alterations of the healing process were found in the groups. The technique using Ligasure transection reinforced by the hydrogel sealant seems to be comparable with the standard transection technique using the stapler.

Delayed and repeated cardiac tamponade following microleak in RCA successfully treated with intra arterial sterile glue injection

Postinterventional pericardial leaks mostly occur intraprocedure or immediately postprocedure and call for an aggressive management right then. Also, once controlled for 24-48 hr, the leaks usually seal themselves spontaneously. We herein describe an unusual case of delayed and continued pericardial leak over 10 days as a result of micro perforation of RCA from the distal wire tip and which was successfully managed by intracoronary injection of sterile synthetic glue, which to the best of our knowledge is the first report of its kind.

A “self adhering” prosthesis for hernia repair: experimental study

Prosthetic reinforcement is now routine in the management of inguinal and incisional hernia, and it significantly reduces the risk of recurrence. After surgery, chronic pain is often attributed to the characteristics of the mesh and to the method of fixation in the wound, with a potential risk of nerve or muscle injuries. To evaluate the properties of a new "self adhering" prosthesis in an experimental animal study. The self adhering prosthesis, a lightweight (40 mg/m(2)) polypropylene mesh coated with a synthetic glue on one side, was implanted laparoscopically in pigs. Removal of the prosthesis was performed at one day, one week and one month post operatively. A macroscopic and microscopic evaluation was performed. The results, using a quantitative score, were compared to those of a control group using the same polypropylene mesh without glue, but fixed by staples. The operative time was significantly lower in the self adhering group: 23 min (15-32) versus 31 min (21-40) (P = 0.01). The average time interval from the introduction of the mesh into the preperitoneal space until the appearance of the first tough adhesion was 3 min (2-4). In the control group, the mesh handling time was 8.3 min (5-14) (P = 0.01). At the time of implantation, the score was at a maximum value in all cases for the self adhering prostheses, especially concerning handling and adhesiveness. Upon removal, this score was noted to be good or very good in 90-100% of the cases. There was a good integration in the muscle confirmed histologically, and there was no shrinkage, no mobilisation and no migration. At one month, the thickness of the fibrosis at the limits of the meshes was significantly higher for the self adhering prostheses (P = 0.02). In this experimental study, the self adhering prosthesis demonstrated its adhesive properties and its ability to be well tolerated, with a good macroscopic and microscopic integration into the abdominal wound. This should allow us to perform a clinical prospective study in an open and laparoscopic approach with the double objective of reducing post operative pain induced by mechanical fixation and decreasing the cost of these procedures by reducing the operative time and by eliminating staple fixation.

Évaluation d’une colle liquide pour la fixation des cathéters périnerveux périphériques

Accidental dislodgement of continuous peripheral nerve catheters remains a frequent problem that causes failure of postoperative analgesia. We have assessed the use of new synthetic glue (Mastisol) to secure and maintain catheters in the correct position among 60 patients. This method allowed securing an effective fixation in 94% of cases,resulting in efficient ambulatory orthopedic surgery postoperative analgesia. No nervous or infectious complications were observed. This technique offers a simple, complementary method to secure peripheral nerve catheters.