Synthesis Of Magnesium Oxide Nanoparticles Research Articles

Photocatalytic degradation of acid violet dye by sunlight exposure using green synthesized magnesium oxide nanoparticles

An aqueous extract of Phyllanthus Emblica fruit extract was used as a precursor in the effective synthesis of Magnesium Oxide Nanoparticles (MgONP) and the same was calcined at different temperatures. The thermal study demonstrated that MgO nanoparticles evolved from Mg(OH)2 by the identification of characteristic weight loss curves and endothermic peaks in TGA and DTA, respectively. UV-visible analysis showed that the peak shifts to a longer wavelength at 350 nm when the calcination temperature rises from 200 to 600 °C, indicating a decrease in the size of MgONP particles. On the other hand, Tauc plot analysis showed that the band gaps between the precursor and calcined MgO samples varied from 5.84 to 3.70 eV. FTIR and XRD analysis confirmed the synthesis of MgONPs from Mg(OH)2 exhibiting spherical shapes of around 20 nm in size.Twenty minutes of exposure to sunshine caused the dye's colour to entirely vanish, demonstrating the remarkable photocatalytic effectiveness of MgONP calcined at 600 °C. The effective breakdown of Acid Violet was confirmed by the rate constant of the photocatalytic behaviour increasing proportionately with the catalyst dose. Furthermore, it was suggested by the Langmuir and Freundlich isotherm models that Acid Violet efficiently adheres to the photocatalyst surface when R2 values are nearer to 1. There are several potential applications for MgO nano adsorbents in dye removal processes, as evidenced by desorption studies that showed their reusability.

Flower extract of Tagetes erecta (marigold) as capping agents for synthesis of magnesium oxide nanoparticles with antioxidant potential

Flower extract of Tagetes erecta (marigold) as capping agents for synthesis of magnesium oxide nanoparticles with antioxidant potential

Biosynthesis of Magnesium Oxide Nanoparticles using <i>Pennisetum Purpureum</i> and Application in Removal of Cadmium Contaminant from Water

This study evaluated an innovative approach to synthesize magnesium oxide nanoparticles (MgO NPs) through a green synthesis method using Pennisetum purpureum extract as a reducing and stabilizing agent. The green synthesis of MgO NPs is cost-effective and environmentally friendly. Characterization techniques such as X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier- transform infrared spectroscopy (FTIR) confirmed the successful synthesis of nanoparticles with unique properties. Debye-Scherrer equation is used for the determination of particle size, which was found to be 15.7nm. The potential application of MgO NPs in the removal of cadmium (Cd) contaminant from water sources was investigated through batch adsorption experiments. Cadmium pollution poses a severe threat to ecosystems and human health due to its toxic nature and persistence in the environment. MgO NPs, with their high surface area and reactivity, efficiently adsorbed and immobilize cadmium ions from water. Adsorption isotherm models indicated that Langmuir isotherm is the best model to describe the adsorption of Cd2+ on magnesium oxide nanoparticles prepared by elephant grass extracts. It was found that a removal of greater percent of Cd2+ could be accomplished through adsorption with 0.05g of magnesium oxide nanoparticles, an initial concentration of metal at 5ppm pH of 10 and at contact time of 65minutes.

Terminalia bellirica (Gaertn.) Roxb. extract-mediated green synthesis of magnesium oxide nanoparticles for multifunctional applications

Green synthesis has emerged as a pivotal facet of nanotechnology, garnering significant attention for its inherent safety and eco-friendly attributes. This study presents a novel approach utilizing phytochemicals derived from Terminalia bellirica (Gaertn.) Roxb. fruit extract for the environmentally benign synthesis of magnesium oxide (MgO) nanoparticles. The resultant MgO nanoparticles were comprehensively characterized using UV–visible spectroscopy, X-ray Diffractometer (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Energy dispersive X-ray (EDX), and High-Resolution-Transmission Electron Microscope (HR-TEM). The synthesized MgO nanoparticles exhibited remarkable stability, evidenced by zeta potential of −8.84 mV and an average size of 73.41 nm. In an eco-physiological context, the application of MgO nanoparticles at a concentration of 5 mg/100 ml significantly enhanced shoot length (7.94±0.70 cm), root length (8.44±0.53 cm), moisture content (97.16±0.83%), and chlorophyll expression (18.34±0.99 mg/g fresh weight (FW)) in Trigonella foenum-graecum seedlings. Furthermore, the MgO nanoparticles demonstrated biocompatibility with soil bacteria and exhibited potent photocatalytic activity, achieving a 42% degradation efficiency of the organic dye methyl orange under UV irradiation for 60 minutes. In the realm of biomedical applications, MgO nanoparticles displayed dose-dependent cytotoxicity against human breast cancer cells (MCF-7), with an IC50 value of 37.39±0.05 µg/ml. Remarkably, MgO nanoparticles were also harnessed for their memcapacitive properties, showcasing excellent non-volatile memory characteristics, including endurance for 15,000 cycles and retention for 4000 seconds. In summary, this study underscores the multifunctional prowess of MgO nanoparticles synthesized through Terminalia bellirica fruit extract, spanning applications in plant physiology, environmental remediation, cancer therapeutics, and nanoelectronics. The environmentally conscious synthesis approach and diverse functionalities presented herein position these nanoparticles as future promising candidates for sustainable and versatile technological advancements.

Syzygium cumini-mediated Green Synthesis of Magnesium Oxide Nanoparticles and Evaluation of their Antibacterial, Antileishmanial, and Antioxidant Activities

Green protocols for the synthesis of nanoparticles have gained significant attention due to their environmental friendliness, ease, and cost-effectiveness. The present study focused on the synthesis of magnesium oxide nanoparticles (MgO-NPs) using an aqueous leaves extract of Syzygium cumini plant, and the antimicrobial potential of the synthesized NPs. Methods: The synthesis of MgO-NPs was achieved by mixing a solution of magnesium nitrate (Mg (NO3)2 with an aqueous extract obtained from S. cumini leaves to reduce the Mg+ ions. These NPs were characterized by X-ray diffraction (XRD), Fourier-Transform Infrared (FTIR) Spectroscopy analysis, Scanning electron microscopy (SEM), and Energy-dispersive X-ray (EDX) analysis. Results: The transformation in color of the solution from yellow to deep brown along with the UV absorption peak at 294 nm showed the effective synthesis of MgO-NPs. SEM and XRD data revealed cubic-shaped NPs with an average size of 23.73 nm. EDX analysis confirmed the presence of magnesium and oxygen in the sample at 31.85% and 35.11% weight percentages, respectively. The antibacterial evaluation demonstrated effectiveness against the gram-negative strains Citrobacter koseri and Pseudomonas aeruginosa, with inhibition zones of 28.1 ± 1.25 mm and 27.8 ± 1.25 mm, respectively. MgO-NPs also showed antileishmanial potential against Leishmania tropica promastigotes (68.41 ± 0.05% inhibition at 1000µg/ml). Furthermore, the NPs exhibited antioxidant properties (75.12 ± 4.29% at 1 mg/ml) as determined by the DPPH radical scavenging assay. Conclusions: MgO-NPs synthesized using S. cumini plant leaves extract hold promises as agents for antibacterial, antileishmanial, and antioxidant applications.

Fabrication and evaluation of Dillenia indica-carrageenan blend hybrid superporous hydrogel reinforced with green synthesized MgO nanoparticles as an effective wound dressing material

An unexplored hybrid superporous hydrogel (MHSPH) of Dillenia indica fruit mucilage (DIFM) and carrageenan blend embedded with green synthesized magnesium oxide nanoparticles (MNPs) is utilized as an effective wound dressing material with appreciable mechanical strength in murine model. The prepared MNPs and the optimized MHSPH were characterized using X-ray diffraction (XRD), thermogravimetric analysis (TGA), Fourier transform infrared (FT- IR) spectroscopy. Size, zeta potential and morphology of MNPs was assessed using Dynamic light scattering technique (DLS) and field-emission scanning electron microscopy (FESEM) respectively. The MHSPH grades were further optimized using swelling study in phosphate buffer solution at pH 1.2, 7.0, and 8. Both MNPs and the optimized grade of MHSPH were evaluated based on hemolysis assay, and protein denaturation assays indicating them to be safe for biological use. Acute toxicity studies of the optimized MHSPH on Zebra fish model, revealed no observable toxic effect on the gill cells. Wound healing in Swiss albino mice with application of optimized grade of MHSPH took only 11 days for healing when compared to control mice where healing took 14 days, thus concluding that MHSPH as an effective dressing material as well as tissue regrowth scaffold.

Green fabrication of tinospora cordifolia-derived MgO nanoparticles: Potential for diabatic control and oxidant protection

Pure and encapsulated magnesium oxide (MgO) nanoparticles were synthesized using a hydrothermal method with Tinospora Cordifolia (TC) leaf extract. XRD analysis revealed a face-centered cubic structure for both types of nanoparticles, with an average crystallite size of 26.94 nm and 36.48 nm. The pure and encapsulated MgO nanoparticles were confirmed by UV-Visible spectrophotometer, the encapsulated MgO nanoparticles had a lower optical energy band gap of 5.304 eV compared to pure MgO nanoparticles at 5.506 eV. FTIR and BET results confirmed the presence of phytochemicals such as phenolic and flavonoid groups encapsulated over the surface of MgO nanoparticles. HRTEM analysis showed nearly spherical shaped encapsulated MgO nanoparticles with a thickness of 8.1 nm. Histogram represents the average particle size of encapsulated MgO NPs was found to be 37.08 ± 4.70 nm. In vitro analysis revealed that these nanoparticles exhibited anti-diabetic and anti-oxidant properties that were comparable to commercially available Metformin drug. The antidiabetic and antioxidant ability of encapsulated MgO NPs was shown by effective inhibition against carbohydrate digestive enzymes such as α- amylase and α-glucosidase with IC50 values of 48.71 µg/ml and 46.29 µg/ml respectively and DPPH radical with IC50 value of 48.012 µg/ml. Encapsulated MgO nanoparticles exhibited higher efficacy in vitro against carbohydrate digestive enzymes and DPPH free radicals than pure MgO nanoparticles due to the presence of phenolic and flavonoid groups. The spectral analysis indicates that the use of Tinospora Cordifolia extract to synthesize MgO nanoparticles results in a green method that shows promise for various biomedical applications.

A Systematic Review of Synthesis MgO Nanoparticles and Their Applications

Recently, nanoscale biotechnology has emerged as an essential field of contemporary science and a new era in the study of materials. It draws the attention of many scientists from all over the world due to its versatility in various fields. Many physical, chemical, and biological processes are used to create biomaterials. Among the materials of interest is magnesium oxide (MgO), which can be widely used in medical and biotechnological applications due to its non-toxicity and environmental friendliness. This review article discusses various methods for the synthesis of magnesium oxide nanoparticles (MgONPs), with particular emphasis on recent developments and applications of these nanomaterials.

Green synthesis of magnesium oxide nanoparticles using endophytic fungal strain to improve the growth, metabolic activities, yield traits, and phenolic compounds content of Nigella sativa L.

Abstract Endophytic fungus Penicillium crustosum EP-1 was used to create spherical shape magnesium oxide nanoparticles (MgO-NPs). The MgO-NPs possess a crystalline structure with sizes of 8–35 nm. The weight percentages of Mg and O were 42.44% and 30.13%, respectively, as shown in energy-dispersive X-ray analysis. In addition, analysis involving dynamic light scattering indicated the uniformity of MgO-NPs within the colloidal solution. These NPs displayed a polydispersity index of 0.341 and held a surface charge of −29.7 mV. A field experimental was carried out to assess the outcome of foliar spraying of MgO-NPs at 5, 10, and 20 ppm on the growth, yield, and metabolic activities of Nigella sativa L. Our results indicated that MgO-NPs significantly enhanced various growth parameters, including chlorophyll content (both a and b), total carotenoids, carbohydrate and protein levels in both shoots and seeds, as well as free proline concentration, compared to the control plants at both 55 and 75 days after planting. In addition, all yield traits were markedly increased. Moreover, high-performance liquid chromatography is employed for the identification of phenolic compounds within the seeds. Data indicated that sex phenolic acids, two phenols, and five flavonoids were present with high concentrations due to MgO-NPs treatment as opposed to untreated plants.

Effective removal of Cr(VI) and Pb(II) ions from mining wastewater using eco-friendly synthesized magnesium oxide nanoparticles incorporated rice husk ash

This study explored the effective adsorptive performance of magnesium oxide (MgO) nanoparticles incorporated rice husk ash (RHA) to address the removal of Chromium (VI) and Lead (II) from mining wastewater from aqueous environment. MgO nanoparticles were synthesized using a magnesium salt precursor and moringa oleifera leaf extract and then impregnated onto RHA to create MgO-RHA nano composite. Different analytical techniques were employed to characterize the RHA and MgO-RHA nanocomposites. The prepared adsorbents were used in batch adsorptive studies and the concentrations of the metal ions were measured before and after treatment using atomic absorption spectrophotometry. Morphological analysis confirmed that the adsorbents developed exhibited a dispersed and porous nature. BET analysis revealed that RHA, MgO, and MgO-RHA had surface areas of 93.04, 32.02, and 102.71 m2/g, respectively. MgO-RHA outperforms RHA in removing metal ions due to its increased surface area and functionality. MgO-RHA demonstrated higher removal percentages of up to 79.20 % and 96.02 % for Cr(VI) and Pb(II), respectively. The Pseudo-second order kinetics and Langmuir isotherm demonstrated the highest degree of conformity to the experimental data, considering the coefficient of determination (R2), smallest value of SSE and chi-square (ᵪ2). Thermodynamic results indicated that the adsorption process was characterized by endothermicity, spontaneity and chemisorption controlled. In summary, the performance of the MgO-RHA nanocomposite surpassed that of RHA alone, which serves as a better adsorbent for metal ion removal.

Magnesium Oxide (MgO) Nanoparticles: Synthetic Strategies and Biomedical Applications

In recent times, there has been considerable interest among researchers in magnesium oxide (MgO) nanoparticles, due to their excellent biocompatibility, stability, and diverse biomedical uses, such as antimicrobial, antioxidant, anticancer, and antidiabetic properties, as well as tissue engineering, bioimaging, and drug delivery applications. Consequently, the escalating utilization of magnesium oxide nanoparticles in medical contexts necessitates the in-depth exploration of these nanoparticles. Notably, existing literature lacks a comprehensive review of magnesium oxide nanoparticles’ synthesis methods, detailed biomedical applications with mechanisms, and toxicity assessments. Thus, this review aims to bridge this gap by furnishing a comprehensive insight into various synthetic approaches for the development of MgO nanoparticles. Additionally, it elucidates their noteworthy biomedical applications as well as their potential mechanisms of action, alongside summarizing their toxicity profiles. This article also highlights challenges and future prospects for further exploring MgO nanoparticles in the biomedical field. Existing literature indicates that synthesized magnesium oxide nanoparticles demonstrate substantial biocompatibility and display significant antibacterial, antifungal, anticancer, and antioxidant properties. Consequently, this review intends to enhance readers’ comprehension regarding recent advancements in synthesizing MgO nanoparticles through diverse approaches and their promising applications in biomedicine.

Synthesis of Magnesium Oxide Nanoparticles for Fabric Coating and its Antibacterial Activities

Conceptually, the present work leads to the synthesis of magnesium nanoparticles (MgO NPs) using pomegranate (Punica granatum L) rind extract for antibacterial fabric coating. The antibacterial performance of MgO NPs on cotton, polyester and blend wool types of fabric was evaluated towards three species of gram-positive bacteria; Staphylococcus epidermidis, Brevibacterium linens and Cutibacteriumacnes. Fourier transform infrared spectroscopy (FTIR) analysis confirmed the successful of sol-gel synthesis process with the presence of flavonoid compounds in MgO NPs solution. The breaking load test was run for all fabric samples, while for tearing strength test, it was carried out only for cotton and polyester fabrics. Air permeability test device was used to determine the air permeability of all fabric samples to ensure the ventilation of the fabrics after coating process. The MgO NPs produced from sol-gel synthesis method established a good antibacterial activity against gram-positive bacteria in all types of fabric samples.

Effect of magnesium oxide nanoparticles and LED irradiation on the viability and differentiation of human stem cells of the apical papilla.

Currently, regenerative endodontic treatments are gaining more and more attention, and stem cells play a significant role in these treatments. In order to enhance stem cell proliferation and differentiation, a variety of methods and materials have been used. The purpose of this study was to determine the effects of magnesium oxide nanoparticles and LED irradiation on the survival and differentiation of human stem cells from apical papilla. The MTT test was used to measure the cell survival of SCAPs that had been exposed to different concentrations of magnesium oxide nanoparticles after 24 and 48h, and the concentration with the highest cell survival rate was picked for further studies. The cells were classified into four distinct groups based on their treatment: (1) control, which received no exposure, (2) exposure to magnesium oxide nanoparticles, (3) exposure to light emitting diode (LED) irradiation (635nm, 200mW/cm2) for 30s, (4) exposure simultaneously with magnesium oxide nanoparticles and LED irradiation. A green approach was employed to synthesize magnesium oxide nanoparticles. Quantitative real time PCR was used to measure the gene expression of osteo/odontogenic markers such as BSP, DSPP, ALP and DMP1 in all four groups after treatment, and Alizarin red S staining (ARS) was used to determine the osteogenic differentiation of SCAPs by demonstrating the Matrix mineralization. The highest viability of SCAPs was observed after 24h in concentration 1 and 10µg/mL and after 48h in concentration 1µg/mL, which were not significantly different from the control group. In both times, the survival of SCAPs decreased with increasing concentration of magnesium oxide nanoparticles (MgONPs). According to the results of Real-time PCR, after 24 and 48h, the highest differentiation of BSP, DMP1, ALP and DSPP genes was observed in the LED + MgONPs group, followed by MgONPs and then LED, and in all 3 experimental groups, it was significantly higher than control group (P < 0.05). Also, after 24 and 48h, the density of ARS increased in all groups compared to the control group, and the highest density was observed in the MgONPs + LED and MgONPs groups. This research concluded that exposure to SCAPs, MgONPs, and LED irradiation has a significant effect on enhancing gene expression of odontogenic/osteogenic markers and increasing matrix mineralization.

In vitro α-amylase/α-glucosidase, cytotoxicity and radical scavenging potential of Hypoxishemerocallidea synthesized magnesium oxide nanoparticles

The prevalence of diabetes has continued to increase over the past decade. Medicinal extract-synthesized nanoformulations incorporating trace elements found in the body have emerged as alternative therapeutic technology for the treatment of diabetes. In this study, magnesium oxide (MgO) nanoparticles were prepared using Hypoxishemerocallidea (HH) and investigated for their cytotoxicity, antioxidant, and antidiabetic potentials. MgO NPs were characterized by transmission electron microscopy (TEM), Fourier-transform infrared (FTIR) spectroscopy, and zeta-potential techniques. TEM analysis confirmed the 2D nanosheet-like morphology of the nanoparticles with particle size (diameter; 300 nm and length of about 1 µm) while the FTIR spectra showed functional groups correlating to the bioactive compounds of HH in the MgO NPs. Moderate antioxidant activity of MgO NPs was observed against DPPH (IC50 = 57.35 ± 0.28 µg/mL) and ABTS (IC50 = 52.08 ± 0.24 µg/mL). The nanoparticles were shown to be less toxic to normal embryonic (HEK293) and human liver (HEPG2) cell lines, with IC50 of 48.63 ± 0.73 and 32.39 ± 0.95 µg/mL, respectively compared to a known cytotoxic drug, doxorubicin which exhibited IC50 of 2.70 ± 0.32 and 8.62 ± 0.57 µg/mL respectively. Besides, the anti-hyperglycemic potential of the MgO NPs as demonstrated by α-amylase and α-glucosidase activities were significantly high with IC50 values of 33.03 ± 1.43 and 52.38 ± 3.06 µg/mL, respectively. These results were compared with an FDA-approved antidiabetic reference standard Acarbose, which exhibited IC50 values of 24.54 ± 1.55 and 6.54 ± 0.27 µg/mL. The results indicated that the HH bioinspired MgO NPs are capable of inhibiting meditators of diabetes and oxidative stress. This study further suggests that the MgO NPs synthesized using HH could be a good candidate for the management of diabetes and other inflammatory diseases due to their strong enzyme inhibition, efficient antioxidant properties, and biocompatibility.

Application of green synthesized magnesium oxide nanoparticles to prolong commercial availability of Vitis vinifera L

The objective of the study was to extend shelf life of Vitis vinifera (L.) by the application of green synthesized Magnesium oxide nanoparticles. Aqueous leaf extract of Azadirachta indica A. juss. and various concentrations of 20 mM, 30 mM, and 40 mM solutions of Magnesium nitrate hexa hydrate salt, were used to synthesize nanoparticles of different size. The characterization of nanoparticles was done by SEM, XRD, and UV. The antimicrobial activity of MgO NPs was evaluated for Azospirilum brasilense and Trichoderma viride, representative of microbes responsible for V. vinifera fruits spoilage. Nanoparticles with crystal size of 28.60 nm has more pronounced effect against microbes. The Shelf life of the Vitis vinifera L. was evaluated by application of 28.60 nm MgO NPs through T1 (nanoparticles coated on packaging), T2 (nanoparticles coated directly on fruit) at 4 °C and 25 °C. T1 at 4 °C was effective to extend the shelf life of Vitis vinifera (L) for an average of 20 days.

Green Synthesis of Bacopa monnieri-Mediated Magnesium Oxide Nanoparticles and Analysis of Their Antimicrobial, Antioxidant, and Cytotoxic Properties.

Background The management of aggressive forms of periodontal disease has become an issue of concern due to the emergence of bacterial resistance. Nanoparticles (NPs) have emerged as a potential therapeutic agent with a multitude of biological functions. The green synthesis of these NPs is more eco-friendly than conventional methods. The present study aimed at the green synthesis of magnesium oxide nanoparticles using Bacopa monnieri (bMgO NPs) and its antibacterial, antioxidant, and cytotoxic analysis. Materials and methods Magnesium oxide NPs were green synthesized using B. monnieri extract using a wet chemical method. The resultant bMgO NPs were assessed for antibacterial activity against Staphylococcus aureus and Escherichia coli. Antioxidant activity was assessed using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay and the hydrogen peroxide (H2O2) assay. Cytotoxicity was assessed using zebrafish viability on treatment with bMgO NPs. Results Compared to the antibiotic standard, the green synthesized bMgO NPs showed good antibacterial properties against S. aureus and E. coli. It also showed excellent antioxidant activity and biocompatibility. Conclusion The bMgO NPs have great potential as a local drug delivery agent and should be further explored for their antibacterial and antioxidant properties in vivo.

Preparations of MgO Nanoparticles by a Poly(acrylic acid)s Template-Assisted Method and Photovoltaic Performances of Dye-Sensitized Solar Cells based on MgO lnterlayer.

Magnesium oxide (MgO) nanoparticles are commonly used to enhance the reactivity and performance of devices and systems in various applications, primarily due to the heat-resistance, binding, and alkaline properties of MgO. However, most of the methods used to synthesize MgO nanoparticles suffer from nonuniform particle size distributions that make it difficult to manufacture stable particles. In this study, uniform magnesium oxide (MgO) nanoparticles were developed for TiO2 photoelectrodes of dye-sensitized solar cells (DSSCs) to enhance their interfacial resistances. The uniform MgO nanoparticles were synthesized from MgO 93% using a poly(acrylic acid) template-assisted method. The particle size and crystalline structure of MgO nanoparticles were characterized by NANOPHOX particle size analysis, transmission electron microscopy, and X-ray diffraction. Multilayered TiO2 photoelectrodes containing interlayers of MgO nanoparticles were fabricated as photoelectrodes for DSSC devices, and their photovoltaic performances were investigated. When the MgO interlayer was introduced into the multilayered TiO2 photoelectrode, it not only increased the photocurrent value of the DSSC device but also improved its power conversion efficiency. The DSSC device containing the MgO interlayer and the scattering layer exhibited an open-circuit voltage of 0.74 V, a short-circuit current density of 14.60 mA/cm2, and a fill factor of 0.64 under a photointensity of 100 mW/cm2 at AM 1.5, resulting in an overall solar energy conversion efficiency of 6.94%. The application of an MgO interlayer in a DSSC device exhibited improved conductivity, charge transfer ability, and excellent device performance.

Evaluation of biogenically synthesized MgO NPs anticancer activity against breast cancer cells

BackgroundMagnesium is recognized to have pharmacological potential, and its nanoformulation is anticipated to offer significant therapeutic effects, particularly against cancer. In this study, we analyzed the anticancer effect of biogenically synthesized magnesium oxide nanoparticles (MgO NPs) against breast cancer cells (MDA-MB-231). MethodsDifferent biological evaluations, such as cytotoxicity, cellular morphology, induction of apoptosis, generation of ROS, cell adhesion and cellular migration were estimated using well established methodology. ResultsThe biogenic MgO NPs exhibited increased cytotoxicity, induced apoptosis, enhanced formation of ROS, promoted cell adhesion and inhibited cellular migration in a dose-dependent manner, showing its therapeutic potential against MDA-MB-231 cells. ConclusionThe current study observed strong anticancer activity of MgO NPs against studied cancer cell lines. However, our study must be validated in an appropriate animal/xenograft model to authenticate the effectiveness of MgO NPs against breast cancer.

Photocatalytic efficacy of Magnesium oxide nanoparticles in dye Degradation: A sustainable One-Pot synthesis utilizing Syzygium samarangense L. Extract

Efficient degradation of organic pollutants is a pressing environmental concern. In our current study, we propose a novel photocatalytic solution to address this challenge, harnessing the potential of advanced nanomaterials to enhance pollutant removal rates. The present work reports the synthesis of Magnesium Oxide (MgO) nanoparticles via a green technique using an aqueous extract of Syzygium samarangense leaves. The role of reducing and capping agents in the process was owned by Syzygium samarangense leaf extract. The green synthesized MgO nanoparticles (MgO NPs) were characterized for their structural, morphology, and optical details using various analytical techniques. The formation of metal oxide in the sample was evident from a strong absorbance peak at 264 nm, and the calculated Eg value of 5.5 eV. The high crystallinity of the prepared NPs was authenticated by PXRD analysis with a cubic structure of calculated average crystalline size of 18 nm. Both leaf extract and the prepared MgO NPs were subjected to FTIR analysis, and the action of phytochemicals was affirmed by the absence of major band in MgO NPs spectrum. Precursor and agglomerated morphology were confirmed on SEM analysis. The prepared sample were utilized to perform degradation of Methylene blue (MB) and congo red (CR) dyes through photocatalysis under UV irradiation. The results affirm the decrement in absorbance with the increment of irradiation time. The affirmed decrement was put forth to study the kinetics of the degradation reaction, and the results was best aligned with 1st kinetic equation with R2 value of 0.9850 and 0.976 for MB and CR dye, respectively. The same results were utilized to study the effect of dye dosage, catalyst concentration, pH level, and presence of different scavengers. All the results found compelling and suggest the prepared MgO NPs as a potent candidate for photocatalytic dye degradation of MB and CR.

Green synthesis and characterization of magnesium oxide nanoparticles for gas sensor application

Green synthesis and characterization of magnesium oxide nanoparticles for gas sensor application