Synthesis Of Phenazines Research Articles

ChemInform Abstract: A New Route for the Synthesis of Phenazine Di‐N‐Oxides.

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A new route for the synthesis of phenazine di-N-oxides

Several phenazine 5,10-dioxides (7a–d) were prepared by the reaction of 2-methyl-3-acetylquinoxaline 1,4-dioxide (2) with different aromatic aldehydes or by direct cyclization of the quinoxaline cinnamoyl derivatives3 in basic medium. In addition, the phenazine derivatives8 and9–12 were synthesized by a one-pot reaction of substitutedo-nitroanilines with different hydroxy compounds in the presence of sodium hypochlorite solution.

Synthesis of 5,7‐dihydrobenzo[a]phenazin‐5‐one derivatives

AbstractThe synthesis, purification and spectroscopic characterization of several phenazines was undertaken with the goal of discovering useful or improved fluorescent probes.

Synthesis of phenazine and phenoxazinone derivatives of geldanamycin as potential polymerase inhibitors

Derivatives of geldanamycin—phenazines and phenoxazinones, some of them analogous to rifazine in the rifamycin series—have been synthesized. Most of the geldanamycin derivatives were highly effective inhibitors of RNA-dependent DNA polymerase from Rauscher leukemia virus. A simple analog containing the aromatic chromophore of the derivatives but without the ansa ring also showed viral inhibition.

Deoxygenation of 2-nitrosophenols and of their metal complexes with triphenylphosphine. Synthesis of phenazines, dihydrophenazines, triphenyl(o-hydroxyphenylimino)phosphoranes and their metal complexes

Deoxygenation of 2-nitrosophenols with Ph3P affords dihydrophenazines, whereas deoxygenation of their NiII, CuII, ZnII, and FeIII complexes yields phenazines or complexes of triphenyl(o-hydroxyphenylimino)phosphoranes depending on the metal; these reactions are interpreted in terms of nitrene intermediates.

Synthesis and pesticidal activity of phenazines. II. Alkyl, alkoxy, alkylthio and alkylsulphonyl phenazines.

AbstractThe synthesis of forty‐one phenazines, mono‐substituted with alkyl, alkoxy, alkylthio and alkylsulphonyl groups is described.Phytotoxicity was highest in the alkyl series and both 1‐ and 2‐methylphenazines are highly effective. herbicides.Although several n‐alkyl, branched alkyl and n‐alkoxyphenazines were highly fungicidal and acaricidal, only 2‐t‐octylphenazine combined high dual activity with negligible phytotoxicity.

Synthesis and pesticidal evaluation of phenazines I.—Halophenazines

AbstractThe synthesis and biological activity of twenty‐six halophenazines is described. the Wohl‐Aue reaction and the new method for cyclisation of 2‐nitrodiphenylamines by oleum were found to be the most convenient methods of synthesis.Phytotoxicity of a characteristic type was higher in foliar spray than in pre‐emergence tests. Chlorine substitution appeared to confer higher activity than other halogen substituents, and in the chlorophenazines activity decreased with increasing substitution. Both 1‐and 2‐chlorophenazine were highly effective herbicides.Acaricidal and fungicidal activity showed similar responses to structural changes, and optimum activity, together with a low level of phytotoxicity, was reached with 1, 4‐dichlorophenazine.

DIRECT RING CLOSURE THROUGH THE NITRO GROUP. ISOMER FORMATION IN THE SYNTHESIS OF UNSYMMETRICAL PHENAZINES, AND SOME GENERAL OBSERVATIONS ON THE PHENAZINE SYNTHESES

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDIRECT RING CLOSURE THROUGH THE NITRO GROUP. ISOMER FORMATION IN THE SYNTHESIS OF UNSYMMETRICAL PHENAZINES, AND SOME GENERAL OBSERVATIONS ON THE PHENAZINE SYNTHESESDONALD L. VIVIAN, GERTRUDE Y. GREENBERG, and JONATHAN L. HARTWELLCite this: J. Org. Chem. 1951, 16, 1, 1–7Publication Date (Print):January 1, 1951Publication History Published online1 May 2002Published inissue 1 January 1951https://doi.org/10.1021/jo01141a001RIGHTS & PERMISSIONSArticle Views187Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (473 KB) Get e-Alerts Get e-Alerts