Synthesis Of Methyl N-phenyl Carbamate Research Articles

Synthesis of methyl N-phenyl carbamate by methoxycarbonylation of aniline with dimethyl carbonate using Pb compounds as catalysts

Methyl N-phenyl carbamate (MPC) is synthesized from aniline and dimethyl carbonate using Pb compounds as catalysts. Using Pb(OAc) 2·Pb(OH) 2 as a catalyst, 97% of aniline present is converted into MPC with 95% selectivity at 453 K in 1 h. In the case of PbO catalyst, an induction period was observed and it disappeared when the catalyst was pretreated with dimethyl carbonate or methanol. The effects of the reaction variables are examined in the reaction using Pb(OAc) 2·Pb(OH) 2 as the catalyst and the reaction mechanism is discussed.

Triphenylphosphine complexes of rhodium and iridium as new homogeneous catalysts for the synthesis of methyl N-phenylcarbamate by carbonylation of nitrobenzene in methanol

The Ph3P complexes of Rh and Ir are active homogeneous catalysts for the synthesis of methyl N-phenylcarbamate by the carbonylation of PhNO2 in MeOH.