You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Quality of Life1 Apr 2013443 NON-UROLOGICAL SYNDROMES AND SEVERITY OF UROLOGICAL PAIN SYMPTOMS: BASELINE EVALUATION OF THE NATIONAL INSTITUTES OF HEALTH MULTIDISCIPLINARY APPROACH TO PELVIC PAIN STUDY John Krieger, Alisa Stephens, J. Richard Landis, Niloofar Afari, Gerald Andriole, J. Quentin Clemens, Karl Kreder, H. Henry Lai, Sean Mackey, Larissa Rodriguez, Anthony Schaeffer, and David Williams John KriegerJohn Krieger Seattle, WA More articles by this author , Alisa StephensAlisa Stephens Philadelphia, PA More articles by this author , J. Richard LandisJ. Richard Landis Philadelphia, PA More articles by this author , Niloofar AfariNiloofar Afari San Diego, CA More articles by this author , Gerald AndrioleGerald Andriole St Louis, MO More articles by this author , J. Quentin ClemensJ. Quentin Clemens Ann Arbor, MI More articles by this author , Karl KrederKarl Kreder Iowa City, IA More articles by this author , H. Henry LaiH. Henry Lai St Louis, MO More articles by this author , Sean MackeySean Mackey Palo Alto, CA More articles by this author , Larissa RodriguezLarissa Rodriguez Los Angeles, CA More articles by this author , Anthony SchaefferAnthony Schaeffer Chicago, IL More articles by this author , and David WilliamsDavid Williams Ann Arbor, MI More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.1833AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES We report data from the Multidisciplinary Approach to Pelvic Pain Study (MAPP) network to: characterize participants having either primarily pelvic pain symptoms or unexplained non-urological somatic syndromes in addition to pelvic pain, with respect to symptoms, psychosocial factors, quality of life, and healthcare utilization. METHODS This multi-site study evaluated men and women with urological pain, including: predominant symptoms, symptom duration and severity, non-urologic syndromes, psychosocial factors, and healthcare utilization in individuals presenting with chronic pelvic pain syndromes. RESULTS Of 443 participants with urological symptoms, 168 (38%) had symptoms of non-urological syndromes: 96 (22%) irritable bowel syndrome, 16 (4%) fibromyalgia, 13 (3%) chronic fatigue syndrome, and 43 (10%) with multiple syndromes. Among 256 females, 112 (44%) had non-urological syndromes compared to 56 (30%) of 187 males (p = 0.003). Patients with non-urological syndromes were younger at diagnosis, had more severe urological symptoms, worse quality of life, and more frequent depression and anxiety. Of 275 patients with urological symptoms only, 188 (68%) were taking prescription medications for their symptoms, compared to 131 (78%) of 168 patients with non-urological syndromes (p = 0.029). Of 443 participants, 236 (53%) met RICE criteria. Among the 236 participants who met RICE criteria, 111 (47%) had non-urological syndromes compared to 57 (28%) of 207 patients not meeting RICE criteria with non-urological syndromes (p < 0.001). CONCLUSIONS Non-urological syndromes represent important phenotypic characteristics in chronic pelvic pain. Since the prevalence of non-urological syndromes was substantially higher in women, this suggests that there may be gender-specific factors which contribute to the urologic pelvic pain symptoms. Patients with both urological and non-urological syndromes had more severe symptoms, decreased quality of life, and higher rates of depression and anxiety. Patients who meet RICE criteria were more likely to have non-urological syndromes and more severe symptoms. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byLai H, Krieger J, Pontari M, Buchwald D, Hou X and Landis J (2015) Painful Bladder Filling and Painful Urgency are Distinct Characteristics in Men and Women with Urological Chronic Pelvic Pain Syndromes: A MAPP Research Network StudyJournal of Urology, VOL. 194, NO. 6, (1634-1641), Online publication date: 1-Dec-2015.Lai H, North C, Andriole G, Cupps L, Song D, Ness T and Hong B (2013) Urological Symptoms in a Subset of Patients with Urological Chronic Pelvic Pain Syndrome and a Polysymptomatic, Polysyndromic Pattern of PresentationJournal of Urology, VOL. 191, NO. 6, (1802-1807), Online publication date: 1-Jun-2014. Volume 189Issue 4SApril 2013Page: e181 Peer Review Report Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information John Krieger Seattle, WA More articles by this author Alisa Stephens Philadelphia, PA More articles by this author J. Richard Landis Philadelphia, PA More articles by this author Niloofar Afari San Diego, CA More articles by this author Gerald Andriole St Louis, MO More articles by this author J. Quentin Clemens Ann Arbor, MI More articles by this author Karl Kreder Iowa City, IA More articles by this author H. Henry Lai St Louis, MO More articles by this author Sean Mackey Palo Alto, CA More articles by this author Larissa Rodriguez Los Angeles, CA More articles by this author Anthony Schaeffer Chicago, IL More articles by this author David Williams Ann Arbor, MI More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...