Since the original roentgen demonstration of symmetrical calcification of the basal ganglia in 1935 by Fritzsche (6) and Kasanin and Crank (7), many cases have been reported. In most of these the calcification has been bilateral and frequently it has been associated with other calcified areas in the cerebrum. Camp (2, 3) mentions two patients with unilateral calcification of the basal ganglia in whom there were no signs or symptoms of brain disease. A case was reported by Rand, Olsen and Courville (9) in which unilateral calcification of the basal ganglia was associated with contralateral extrapyramidal symptoms. It is the purpose of this report to call attention to another example of isolated unilateral opacification of the basal ganglia of sufficient degree to be demonstrated radiologically and associated with signs and symptoms of extrapyramidal disease on the contralateral side of the body. Case Report V. G. K., a 33-year-old white married female, was referred to Barnes Hospital from the Out-patient Department because of a drawing sensation in the left hand, leg, and face of fifteen years duration. She had first noticed stiffness of the fingers of the left hand and a rather rigid gait at the age of eighteen. One year later she began to experience drawing sensations in the left forearm, transmitted to the fingers. Although the stiffness persisted, no apparent disability resulted. The patient had always been able to fully flex and extend the fingers of her left hand ; she was able to comb her hair and perform other skilled tasks with both hands. Occasionally she had experienced mild numbness in both forearms when lying down in the daytime. During the past two years she had noted some increase in the drawing sensation in the left forearm and hand, most pronounced when she was fatigued. In the past two months there had been a few episodes of left-sided headaches and a tendency for the left corner of the mouth to be drawn laterally. At the age of twenty-eight, the patient had contracted gonorrhea and shortly afterward divorced her husband. During this period of marital strife she began to vomit at frequent intervals, with no relation to food intake and no associated abdominal pain, hematemesis, or melena. She was seen in the Neuropsychiatric Clinic, where extensive interviews led to a diagnosis of conversion hysteria, but no long-term psychiatric treatment was instituted. On physical examination the patient appeared well developed and well nourished. The fingers of the left hand were held stiffly extended (Fig. 1); they flexed easily and completely, both actively and passively, but there was some difficulty in abduction. Slight cog-wheel rigidity was noted at the left elbow. There was mild dysdiadokokinesis of the left hand but no dysmetria or loss of proprioception. On walking, the left knee was somewhat rigid, but there was a full range of passive and active motion of the joint. The deep reflexes were normal.