Symptoms In Daily Life Research Articles

Children's perception and interpretation of anxiety-related physical symptoms

The present study examined children's perception and interpretation of anxiety-related physical symptoms in a sample of 4–12-year-old primary school children ( N=129). Children were presented with neutral scenarios in which the main character experienced an anxiety-related physical symptom (e.g., hands trembling, heart beating very fast), and asked to attribute various emotions to this character. Children were also interviewed about idiosyncratic experiences with anxiety-related physical symptoms. Results showed that physical symptoms were associated with a broad range of emotions. “Hands trembling”, “heart beating fast”, and “difficulties with breathing” were the only symptoms that were more frequently linked to fear than to other emotions. Furthermore, developmental patterns were found for fear-related interpretations of physical symptoms. That is, from the age of 7, children more frequently associated physical symptoms to fear. Finally, children reported to experience anxiety-related physical symptoms in daily life, although frequently not in relation to fearful situations and circumstances.

成長期の下肢長管骨に発生したＢｒｏｄｉｅ膿ようの２例

We report two Brodie's abscess located in the metaphysis of the long bone which penetrated the growth plate. In the one case, a 14-year-old girl, the abscess extended in the distal metaphysis and epiphysis of her right femur. Her epiphyseal cartilage had already ossified on radiography, and curetting was performed over the growth plate leaving the drainage tube in the dead space. In the other case, a 13-year-old girl, the abscess spread from the distal metaphysis to the epiphysis of her right tibia. In this case the epiphyseal cartilage still existed, so we curatted only the metaphyseal lesion from apprehension of growth disturbance. Both cases were observed for over six months, during which time experience any symptoms in daily life nor did growth disturbance of the bone progress.

Social environments and daily life occurrence of psychotic symptoms--an experience sampling test in a non-clinical population.

If impairment in social cognition is an important feature of psychosis, characteristics of the social environment may influence the occurrence of psychotic symptoms. The aim of this study was to explore in a non-clinical population whether specific social environments modify the expression of psychotic symptoms in daily life. The Experience Sampling Method was used to collect information on characteristics of the social company and of the daily life psychotic experiences of a sample of 79 students. The level of psychotic symptoms was measured using the Mini International Neuropsychiatric Interview (MINI). Subjects with MINI psychosis criteria were at increased risk of experiencing unusual perceptions in the presence of non-familiar individuals, and at lower risk of experiencing strange impressions in the presence of family members or friends. Dynamic changes in the social company rather than the social company per se drive variation of psychotic experiences in daily life. The data suggest that the earliest stages of expression of psychosis vulnerability are driven by subtle person-environment interactions in the stream of daily life.

Resting end-tidal CO2 and negative affectivity.

Dhokalia, Parsons, and Anderson (Psychosom Med 1998;60:33-37) found a positive correlation between a trait measure of negative affectivity (NA; neuroticism) and resting end-tidal fractional concentration of CO2 (FetCO2) (fractional-concentration of end-tidal carbon dioxide) in a nonclinical sample. This contrasts sharply with studies reporting a negative association of FetCO2 with state measures of NA and with studies reporting no or a negative relationship between FetCO2 and trait NA. In two studies we aimed to clarify this paradox. In the first study, 110 participants (83 women) completed the PANAS and a Checklist for Psychosomatic Symptoms in daily life. FetCO2 was measured noninvasively during 5 minutes via a nose cannula connected to a capnograph. In the second study, FetCO2 of high (N= 20, 10 men) and low (N= 20, 10 men) NA participants was sampled once with a nasal cannula and once while breathing through a mouthpiece for 6 minutes each during rest, completion of the NEO-PI-R questionnaire, and completion of a verbal knowledge test. The first study found no association between trait NA and resting FetCO2 after partialling out the effects of gender, menstrual phase, and use of oral contraceptives. The second study showed that FetCO2 increased significantly in the high NA group only when the particpants filled out the questionnaires, regardless of its type. Overall, no association between dispositional NA and cross-situational FetCO2 was observed. Apparently inconsistent findings may be caused by lack of control for hormonal status and mental load during testing.

Online monitoring of dyskinesia in patients with Parkinson's disease.

Discusses utilizing wearable movement sensors to successfully detect and assess severity of Parkinsonion symptoms in daily life. The authors describe the present state-of-the-art of online monitoring of motor behavior. They focus on modern monitoring equipment and on new analysis tools, which allow a quantitative detection and assessment of dyskinesias throughout the day, by an objective, unsupervised rating of dyskinesias using clinical rating scores.

Relations of intrinsic spirituality with health status and symptom interference.

The purpose of this study was to examine the relationships between spiritual experience and current health status and between spiritual experience and subjective experience of symptom interference. Symptom interference is the extent to which symptoms of physical or psychological illness limited participants' activities of daily living. Participants were 49 volunteers who were enrolled in a spiritual fitness class at a variety of denominational Christian churches in Plano, Texas. The sample ranged in age from 22 to 65 years, and 84% were women. The Index of Core Spiritual Experiences and the Medical Symptoms Checklist were administered. Current health status and symptom interference were utilized from the self-report checklist. It was predicted that Index scores would be significantly different based on participants' health status and that Index scores would correlate significantly with participants' ratings of symptom interference. Analysis indicated that Index scores were significantly higher (p = .02) for participants with no current medical diagnosis than for those currently experiencing either a life-threatening or a chronic medical or psychological disorder. Also, the percentage-bend correlation between Index scores and scores for interference of symptoms in daily life was significant ((r)Pb = -.33, p = .02). These results suggest that the report of core spiritual experiences may be related to better current health status. These findings have implications for understanding the role of spirituality in the prevention of illness and in an individual's ability to cope with illness.

Management of the urethral outlet in patients with severe prolapse.

Numbers of women seeking consultation for pelvic floor disorders, a large portion of which will involve pelvic organ prolapse (POP) and lower urinary tract dysfunction, are expected to reach epidemic proportions within the next decade. A full understanding of the complex impact of pelvic organ prolapse on lower urinary tract function is crucial to successful management. Recent data lend support to the concept that women with POP, but no associated urethral dysfunction, may be best served by a surgical repair that carefully avoids dissection in the periurethral area. Conversely, preoperative evaluation will often reveal bladder outlet obstruction concomitant with 'hidden', 'potential', or 'occult' stress urinary incontinence when the prolapse is reduced. Many of these women will not have incontinence symptoms in daily life. Paradoxically, the mechanical bladder outlet obstruction may induce detrusor instability with subsequent obstructed/overactive bladder symptom complexes not dissimilar to those of men with prostatic bladder outlet obstruction. Anatomic research shows that the vessels and nerves supplying the urethra are particulary vulnerable to surgical techniques used in pelvic organ prolapse repair. This mix of obstructed, overactive bladder with hidden stress incontinence increases with degree of POP, and all women with severe prolapse will fair best if evaluated for all three conditions prior to surgical repair.

Quality of Life in Patients with Upper Gastrointestinal Symptoms: Results from the Domestic/International Gastroenterology Surveillance Study (DIGEST)

Background: Our purpose was to evaluate the impact of upper gastrointestinal (GI) symptoms on quality of life (QoL), which was assessed using the Psychological General Well-Being Index (PGWBI) and the three-item Interference with Daily Life Index (IDLI). Methods: The Domestic/International Gastroenterology Surveillance Study (DIGEST) was conducted among 5581 respondents (mean age 44 years) from 10 countries (seven European countries plus Canada, USA and Japan). Results: Approximately 25% of the respondents reported conditions such as hypertension, asthma or diabetes, and a mean of 46.4% reported at least one GI symptom. The most frequent symptoms were heartburn, diarrhoea and postprandial fullness. Approximately 10-20% of the respondents reporting individual symptoms experienced these several times a week. Symptoms were considered as severe or interfering 'quite a lot' with daily activities by at least 7.3% and 4.8% of respondents, respectively. PGWBI scores varied from 71.82 (Italy) to 79.43 (Switzerland) and daily activity scores from 88.62 (USA) to 97.78 (Switzerland). Female gender, medical conditions and presence of GI symptoms were associated with significantly impaired wellbeing and daily life. PGWBI and IDLI scores were lower among respondents with relevant upper GI symptoms than non-upper GI symptoms. Among upper GI symptom groups, subjects with ulcer-like symptoms had lower scores than patients with GERD-like or dysmotility-like symptoms. PGWBI and IDLI scores were found to discriminate between respondents reporting different symptom frequencies and severities. Conclusions: Results from the DIGEST demonstrate on a large scale the importance of GI symptoms in daily life and their influence on QoL.

Subjective symptoms and breathing pattern at rest and following hyperventilation in anxiety and somatoform disorders

The purpose of the present study was to investigate the diagnostic specificity of bodily symptoms and respiratory behavior at rest and after a hyperventilation provocation test (HVPT) in patients that were either grouped according to the DSM classification or diagnosed as suffering from hyperventilation syndrome. Nine hundred three anxiety and somatoform patients, showing symptoms supposedly caused by psychogenic hyperventilation, and 170 healthy subjects, were studied. Breathing pattern and end-tidal CO 2 concentration were recorded during breathing at rest and following a HVPT. Subjective symptoms in daily life and after HVPT were measured. A principal-components analysis was performed on both the symptoms and breathing variables and their specificity levels were compared in the two classifications of patients. Some symptoms in daily life were grouped together with the same symptoms after the HVPT, other symptoms were not. This suggests that the HVPT elicited partly specific symptoms, and partly reproduced the symptoms experienced in daily life. Similar findings were observed with respect to the breathing variables. Patients with panic differed from other patients with anxiety disorders by an increased level of symptoms and a FETCO 2 decline at rest. The HVPT may be informative for diagnosis because it provokes some of the typical somatic and psychological symptoms, and it identifies the breathing instability that is characteristic of both patients with HVS and with anxiety. The same symptoms and breathing variables characterized the patients, whatever their classification. Overall, the specificity of breathing variables is rather low.

Importance of Total Leg Muscle Mass for Exercise Intolerance in Chronic Heart Failure.

Patients with chronic heart failure symptoms tend to avoid voluntary effort and are thus subject to physical deconditioning. The presence of symptoms in daily life is thought to predispose to physical deconditioning and subsequent skeletal muscle loss. This study was designed to describe the relation among daily physical activities, skeletal muscle loss and exercise capacity in patients with chronic heart failure. We studied 14 patients with severe cardiac dysfunction (left ventricular ejection fraction < 40%) and 7 age-matched normal subjects. We measured total leg muscle mass by dual energy X-ray absorptiometry. The patients were divided into 7 asymptomatic and 7 symptomatic individuals using questionnaires for specific physical activities. Peak oxygen uptake and anaerobic threshold were significantly reduced in cardiac patients as compared with normal subjects. The reduction in exercise capacity was greater in the symptomatic patients than in asymptomatic patients. Leg muscle mass was significantly reduced (-17%) in the symptomatic patients, while it remained normal in the asymptomatic patients. Oxygen uptake in unit muscle mass at the level of anaerobic threshold and at peak exercise was decreased in both the asymptomatic (-21% and -21%, respectively) and symptomatic patients (-27% and -30%, respectively) but the difference between these two groups was not significant. In the asymptomatic patients, the reduced exercise capacity was accounted for primarily by muscle mass-independent factors such as an impaired nutritive blood flow to exercising muscles or metabolic abnormalities within the muscle cell. In the symptomatic patients, the marked reduction in exercise tolerance was attributable to a decrease in leg muscle mass and to hemodynamic or metabolic abnormalities. We conclude that the loss of leg muscle mass plays an important role in exercise intolerance in patients who are prone to physical deconditioning as a result of symptomatic heart failure.