The utilization of swirling flow in multiphase flow devices is prevalent for purposes such as mixing, separation, stabilization, and heat transfer enhancement, primarily owing to its characteristic of inducing low-pressure drop. In the nuclear industry, for example, two-phase swirling flow is applied in the nuclear gas generator to improve gas quality. In this study, an experimental investigation was conducted on the decaying swirling flow of gas-liquid in a horizontal pipe equipped with a vane-type swirler. The flow patterns were visually examined, and the pressure gradients along the test pipe and across the swirler were measured. The findings suggest the presence of four distinct swirling flow patterns at the swirler outlet (z/D = 0), namely chain flow, swirling gas column flow, swirling intermittent flow, and swirling annular flow. Because of swirl decay, these swirling flows recover their original pattern approximately 70D downstream from the swirler, with the exception of the swirling gas column flow. The flow regime maps at z/D = 10, 40, 70 and 100 are proposed and the pattern-based pressure gradient characteristics are analyzed. It is shown that the pressure gradient rises as both gas superficial velocity (jg) and liquid superficial velocity (jl) increase. The largest pressure gradient occurs within the swirler section, while the lowest is found upstream of the swirler. Near the swirler outlet (z/D = 0–33), the pressure gradient is approximately 1.5–2.3 times higher than at z/D = 33–67. Further downstream, at z/D = 67–100, it is 2.2–3.5 times greater, depending on the flow patterns.