ABSTRACTFarmers are looking for better management practices to utilize animal manure as an alternative to chemical fertilizers. A 2-year field experiment was conducted to study the effects of nitrogen (N) fertilizer source and application methods to Nicholson silt loam soil in central Kentucky, USA for no-till corn (Zea mays) production. The region has a temperate climate with a mean temperature of 14.5°C and rainfall of 1300 mm year−1. Treatments included a control, 179 kg N ha−1 urea ammonium nitrate (UAN) applied as preplant and sidedress, and swine effluent that was applied by three methods: broadcast, injection, and Aerway. Injection method produced the greatest corn grain yield (11.88 Mg ha−1) and biomass yield (18.9 Mg ha−1) in 2007. Results demonstrated that the effluent application methods and the timing of UAN application may not be agronomically important for corn production in this region. Hence, more studies are needed on different soils in this region.