Sweet Water Research Articles

Sweet and Salty Drinking Water Coming to a Tap Near You

Sodium and two popular artificial sweeteners, sucralose and acesulfame, are poorly removed by conventional water and wastewater treatment. The drinking water industry must prepare for the presence of these tastants in tap water and develop strategies to minimize effects on the public.

Effect of Relative Sowing Time on the Growth and Yield of Sweet Corn and Water Melon Intercropping

Effect of Relative Sowing Time on the Growth and Yield of Sweet Corn and Water Melon Intercropping

Physicochemical, structural and metabolic products of yogurt as affected by Coriolus versicolor fermented sweet potato pulp water

Sweet potato pulp water (SPPW) is a kind of sweet potato starch processing by-product with rich nutrition but low utilization. The impacts of different proportions of Coriolus versicolor (C. versicolor, CV) fermented sweet potato pulp water (CV-SPPW) on the physicochemical, structural and metabolic properties of yogurt were investigated. Compared with 0% group, the hardness index, elasticity index and cohesion of the 10% sample group increased by 1.9-fold, 55.7% and 1.39-fold, respectively. When CV-SPPW was added at an amount of 10%, the microstructure and sensory scores of yogurts were considered as the optimal. Metabolic pathway analysis indicated that the changes of yogurts were mainly involved in sugar metabolism and amino acid metabolism, and that the carbohydrate metabolites produced mainly included cellobiose, maltitol, d-trehalose and d-maltose. The CV-SPPW improved the structural characteristics of yogurts to varying degrees and the fermented yogurts exhibited better viscosity properties.

EOQ Optimization Revolutionizes Inventory Management, Delivering Cost Savings Globally

Efficient inventory management is crucial for companies to minimize costs while ensuring adequate supply to meet demand. PT Samawa Tirta Alam, a bottled sweet drinking water company, faces significant inventory management issues, notably with refined sugar raw materials. High transportation costs and fluctuating demand contribute to excessive inventory accumulation and increased storage costs, necessitating an optimization strategy. This study implements the Economic Order Quantity (EOQ) method to address these challenges. Through a mixed-method approach, qualitative data were gathered via observations and interviews, while quantitative analysis utilized historical data to calculate optimal order quantities, frequencies, safety stock levels, and reorder points. Results demonstrate substantial cost savings, with optimal order quantities determined, reducing order frequencies from 12 to 2 times per year, and minimizing safety stock levels. The findings underscore the effectiveness of the EOQ method in enhancing cost-effectiveness and operational performance in raw material inventory management for similar companies. Highlights: 1. Cost Efficiency: EOQ method reduces total inventory costs effectively.2. Operational Precision: Minimizing safety stock enhances operational efficiency.3. Strategic Insight: Integrated approach provides practical solutions for inventory management challenges. Keywords: Inventory Management, Economic Order Quantity (EOQ), Cost Optimization, Raw Materials, Transportation Costs

N-glycosylation of SCAP exacerbates hepatocellular inflammation and lipid accumulation via ACSS2-mediated histone H3K27 acetylation.

Sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) is a widely expressed membrane glycoprotein that acts as an important modulator of lipid metabolism and inflammatory stress. N-glycosylation of SCAP has been suggested to modulate cancer development, but its role in nonalcoholic steatohepatitis (NASH) is poorly understood. In this study, the N-glycosylation of SCAP was analyzed by using sequential trypsin proteolysis and glycosidase treatment. The liver cell lines expressing wild-type and N-glycosylation sites mutated SCAP were constructed to investigate the N-glycosylation role of SCAP in regulating inflammation and lipid accumulation as well as the underlying mechanisms. The hepatic SCAP protein levels were significantly increased in C57BL/6J mice fed with Western diet and sugar water (WD + SW) and diabetic db/db mice, which exhibited typical liver steatosis and inflammation accompanied with hyperglycemia. In vitro, the enhanced N-glycosylation by high glucose increased the protein stability of SCAP and hence increased its total protein levels, whereas the ablation of N-glycosylation significantly decreased SCAP protein stability and alleviated lipid accumulation and inflammation in hepatic cell lines. Mechanistically, SCAP N-glycosylation increased not only the SREBP-1-mediated acetyl-CoA synthetase 2 (ACSS2) transcription but also the AMPK-mediated S659 phosphorylation of ACCS2 protein, causing the enhanced ACSS2 levels in nucleus and hence increasing the histone H3K27 acetylation (H3K27ac), which is a key epigenetic modification associated with NASH. Modulating ACSS2 expression or its location in the nuclear abolished the effects of SCAP N-glycosylation on H3K27ac and lipid accumulation and inflammation. In conclusion, SCAP N-glycosylation aggravates inflammation and lipid accumulation through enhancing ACSS2-mediated H3K27ac in hepatocytes.NEW & NOTEWORTHY N-glycosylation of SCAP exacerbates inflammation and lipid accumulation in hepatocytes through ACSS2-mediated H3K27ac. Our data suggest that SCAP N-glycosylation plays a key role in regulating histone H3K27 acetylation and targeting SCAP N-glycosylation may be a new strategy for treating nonalcoholic steatohepatitis (NASH).

Sweet and sour sips: No effect of repeated exposure to sweet or sour-tasting sugary drinks on children's sweetness preference and liking

Health agencies advocate reducing children's sweetness exposure to lower sweetness preference or liking to ultimately lower sugar intake. However, the relationship between sweetness exposure, preference, and liking remains unclear. This work investigated the influence of exposure to a sucrose-containing sweet or sour-tasting drink on sweetness preference and liking for sweet and sour products in 4-7-year-old children (n = 65). The children were randomized into three groups with one daily exposure to either the sweet drink, sour drink, or water (control group) for 14 days. Sweetness preference was assessed at baseline (t1), day 15 (t2), and two months after the intervention (t3), using a forced-choice, paired comparison test with five beverages varying in sweetness intensity. Hedonic liking for the intervention drinks, a sweet and sour yogurt, and a sweet and sour candy was evaluated using a 5-point pictorial scale. Linear mixed models revealed a significant increase in sweetness preference from t1 to t3 (F(2) = 7.46, p < 0.001). However, ANCOVA analysis indicated that this effect was not caused by the intervention. Based on linear mixed models, we observed that children's hedonic liking for sweet and sour products remained stable from t1 to t3 and was not influenced by the intervention. These findings suggest that 14 exposures to a sucrose-containing sweet or sour-tasting drink did not affect sweetness preference or liking in 4-7-year-old children.

The cerebellum directly modulates the substantia nigra dopaminergic activity.

Evidence of direct reciprocal connections between the cerebellum and basal ganglia has challenged the long-held notion that these structures function independently. While anatomical studies have suggested the presence of cerebellar projections to the substantia nigra pars compacta (SNc), the nature and function of these connections (Cb-SNc) is unknown. Here we show, in mice, that Cb-SNc projections form monosynaptic glutamatergic synapses with dopaminergic and non-dopaminergic neurons in the SNc. Optogenetic activation of Cb-SNc axons in the SNc is associated with increased SNc activity, elevated striatal dopamine levels and increased locomotion. During behavior, Cb-SNc projections are bilaterally activated before ambulation and unilateral lever manipulation. Cb-SNc projections show prominent activation for water reward and higher activation for sweet water, suggesting that the pathway also encodes reward value. Thus, the cerebellum directly, rapidly and effectively modulates basal ganglia dopamine levels and conveys information related to movement initiation, vigor and reward processing.

Understanding Resource Recycling and Land Management to Upscale Zero-Tillage Potato Cultivation in the Coastal Indian Sundarbans

Upscaling sustainable intensification (SI) technologies is crucial to enhancing the resilience of fragile farming systems and vulnerable livelihoods of smallholder farmers. It is also critical to shape the future land-use and land-cover changes in a region. Zero-tillage potato cultivation (ZTPC), introduced as an SI intervention in parts of the Indian Sundarbans, has demonstrated promises of rapid upscaling, and thus, changes in the seasonal land-use pattern in the region. This study aims to understand the socioecological complexity of farming systems to comprehend how the nascent stage of ZTPC thrives at the farm level and what preconditions are necessary to upscale them. The objectives are to analyse the farm resource recycling pattern in ZTPC, and map and simulate its system’s complexity to strategize ZTPC upscaling in the region. The analysis of farm resource recycling data reveals that ZTPC stability hinges on managing trade-offs in resource allocations, specifically involving straw, organic manure, sweet water, and family labour. The decision to manage such trade-offs depends on farm type characterizations by their landholdings, distance from the homestead, pond, and cattle ownership, competing crops, and family composition. Using a semiquantitative systems model developed through fuzzy cognitive mapping, the study underscores the significance of effective training, input support, enterprise diversification by introducing livestock, timely tuber supply, access to critical irrigation, and capacity building of local institutions as the essential preconditions to sustain and upscale ZTPC. This research contributes a systems perspective to predict agricultural land use within technology transfer initiatives, providing insights into how farm- and extra-farm factors influence resource allocations for ZTPC. Public extension offices must understand the trade-offs associated with straw, organic matter, and harvested water and design differentiated supports for different farm types. The most compelling interventions to upscale ZTPC includes farm diversification by introducing livestock through institutional convergence, pragmatic agroforestry initiatives to enhance on-farm biomass and fuel production, building awareness and integrating alternative energy use to save straw and cow dung, building social capital to ensure access to sweet irrigation water, and developing and/or strengthening farmer collectives to ensure the supply of quality tuber and marketing of farm produce.

INFLUENCE OF A TWO-STAGE HEAT RECOVERY SCHEME ON THE OPERATION OF THE PV-MD COLLECTOR

Production efficiency of the electric power the solar module is essentially defined by a thermal operating mode. One of progressive ways of affecting on a thermal regime is vapour cooling which at distillation of saliferous waters gives the chance to operate temperature of the solar cell and to gain a by-product in the form of sweet water. At cascade multistage recoveryevaporation heats samplingof the circuit solution of a process of cooling allows to optimise a combination of electric and distillation productivity of the photomodule. The analysis of formation of temperature pattern of an absorber of a hybrid solar collecting channel (PV-MD), a salt solution chilled at two-level distillation with recoverywarmth of steam is in-process carried out. The analysis method allows to investigate PV-MD-collecting channel characteristics - temperatures of an absorber and heat-transfer agent, productivity of system on the electric power and distillate at implementation of counter flow and direct-flow circuit designs of traffic of a solution, and also depending on module working conditions. The work purpose - synthesis of a method of calculation of opeating characteristics of a hybrid solar collecting channel with the finestiller at the cascade way Heat and mass transfer heat-transfer agent and revealing of the rational technological circuit design of the device. The mathematical model of a hybrid solar collecting channel is characterised by possibility of the local analysis of processes Heat and mass transfer for real conditions of a solar and climatic situation. The analysis Heat and mass transfer in alternative conditions showed that sampling of the circuit design of traffic of heat-transfer agent practically does not depend on electric power conditions of production, but is essentially defined by agency of directions of streams of heat-transfer agent on distillation process. On conditions of rationalisation of process of distillation for achievement of the greatest level of production of distillate the circuit design of direct-flow cascade traffic of a solution is effective. Keywords: hybrid solar collector, method PV-MD, temperature regime, distillate production, electricity production

Integrating machine learning and empirical evapotranspiration modeling with DSSAT: Implications for agricultural water management

The availability of accurate reference evapotranspiration (ETo) data is crucial for developing decision support systems for optimal water resource management. This study aimed to evaluate the accuracy of three empirical models (Hargreaves-Samani (HS), Priestly-Taylor (PT), and Turc (TU)) and three machine learning models (Multiple linear regression (LR), Random Forest (RF), and Artificial Neural Network (NN)) in estimating daily ETo compared to the Penman-Monteith FAO-56 (PM) model. Long-term data from 42 weather stations in Florida were used. Moreover, the effect of ETo model selection on sweet corn irrigation water use was investigated by integrating simulated ETo data from empirical and ML models using the Decision Support System for Agrotechnology Transfer (DSSAT) model at two locations (Citra and Homestead) in Florida. Furthermore, a linear bias correction calibration technique was employed to improve the performance of empirical models. Results were consistent in that the NN and RF models outperformed the empirical models. The empirical models tended to underestimate and overestimate small and high daily ETo values, respectively, with the HS model exhibiting the least accuracy. However, calibrated PT and TU models performed comparably to the ML models. Results also revealed that using an inappropriate ETo model could lead to over-irrigation by up to 54 mm during a single crop season. Overall, ML models have proven reliable alternatives to the PM model, especially in regions with access to long-term data due to their site-independent performance. In areas without long-term data for ML model training and testing, calibrating empirical models is viable, but site-specific calibration is needed. It is important to highlight that distinct plant species exhibit varying transpiration characteristics and, consequently, have different water requirements. These differences play a pivotal role in shaping the overall impact of ETo models on crop water use.

Examination of Food Preference and Aggressive Behavior in Nest Cohabitation among Ponerines

Environmental stress such as competition is one of the key factors that affecting the behavior of ants. This essay explores food preference and aggressive behavior changes of ponerines (Harpegnathos venator and Diacamma rugosum) when they were in nest cohabitation. Since there were no variations in stinging time and prey recovery time, our results indicated that cohabitation has no influence on the aggressive behavior of H. venator. On the other hand, food preference of D. rugosum demonstrated a shift towards fruit, vegetable, and sweet water, with less interest in cherry-red cockroaches and crickets. Although H. venator still predominantly prefers cherry-red cockroaches and crickets, their prey contacting time was decreased. These results emphasized the ability of ponerines to adapt their foraging strategy to competition, highlighting the dynamic nature of predator-prey interactions in cohabiting environments.

Can Purple Sweet Potato Water Extract (Ipomoea batatas L.) Induce Steatosis at Toxic Doses in Rat?

Purple sweet potato (Ipomoea batatas L.) has a secondary metabolite that contains a lot of antioxidants. Some of the secondary metabolites in purple sweet potato have a hepatotoxic effect. Objective: To described the toxic effects of purple sweet potato water extract on steatosis in rats. Methods: This descriptive study was conducted on 29‒30 June 2019 in the Biomedical Laboratory of the Faculty of Medicine, Islamic Bandung University, with an in-vivo experimental design with random allocation techniques and using the proposed new method on 11 rats. One of the control rats was not given extract, and ten other rats were given a dose of purple sweet potato water extract 50, 200, 400, 800, 1000, 1500, 2000, 3000, 4000, and 5000 mg/KgBW/PO. The liver organ was harvested after 24 hours, and then slides were made at the Pathology Anatomy Laboratory of Padjajaran University. Results: The histopathological view did not find any steatosis either in macrovesicular or microvesicular, but other features were found in ballooning degeneration, sinusoidal dilation, and inflammation. Conclusion: Steatosis was not found because purple sweet potato contains anthocyanins and tannins.Keywords: purple sweet potato, steatosis, tannin

Scalable, Green, and Cost-Effective Carbonized Sand for Efficient Solar Desalination.

Nowadays, sweet and drinkable water shortage is a global issue which has attracted widespread attention. Desalination of seawater as the greatest source of water on our planet using solar energy as the most abundant and green energy source for producing fresh water can help us address this issue. Interfacial solar desalination is a state-of-the-art, sustainable, green, and energy-efficient method that has been studied lately. One of the key parameters for researching this method with reasonable efficiency is a photothermal material. Herein, carbon-coated sand was synthesized using abundant, green, and low-cost materials (sand and sugar), and its performance as a photothermal material is investigated and reported. In this work, a three-dimensional (3D) system is introduced to develop the performance and efficiency of the system under real sun irradiation and natural circumstances. The salt rejection ability of the system is another important thing we should notice due to the high salinity of seawater that we want to desalinate. The superhydrophilic carbonized sand demonstrated a good evaporation rate of 1.53 kg/m2h and 82% efficiency under 1 sun irradiation and upright salt rejection ability, which exhibited its capability to be used in green solar-driven water vaporization technology for sweet water production. The effects of important parameters, including light intensity, wind speed, and environment temperature, on the evaporation rate using carbonized sand as a solar collector in a solar desalination system were studied in both laboratory and real systems.

Effect of irrigation and fertiliser doses on sweet corn yield, water consumption and water utilization

The experiment was conducted within a framework of a two-factor long-term trial at the Research Institute for Fisheries, Aquaculture and Irrigation, in Szarvas, Hungary. This was a special field experiment, in which lysimeters have been installed in the middle of 32 m2 field plots. The main factor was the water supply with 4 levels: i1: non-irrigated control; i2: irrigated with one third of the optimal water supply; i3: irrigated with two thirds of the optimal water supply; i4: optimum irrigated plot, according to the requirement of sweet corn test plant. The amount of released irrigation water was 0, 54, 106 and 158 mm per year on average over 5 years. Within every water supply treatment there were 4 nutrient supply rates (N): N1, N2, N3, N4 = 100, 200, 300 and 400 kg ha−1 NPK fertiliser substance in ratio 2:1:1. The number of replications was 4, and the experiment was arranged in split-plot design. In the studied years, the amount of precipitation varied between 92 and 264 mm from sowing to harvesting.The effect of fertiliser was less in the non-irrigated treatments compared to that of the irrigated ones, and the yield was increased only up to 200 kg ha−1 NPK treatment level. The NPK dose of 300 kg ha−1 proved to be optimal in the irrigated treatments in which the utilization of fertilizer doses increased parallel to the improving water supply. In addition, the ratio of first class products (cobs longer than 20 cm) increased to a greater extent than the yield as a result of irrigation and fertilization. Water requirement of sweet corn proved to be between 400–450 mm resulting in an average yield of 20–24 t ha−1, of which 18–20 t ha−1 came from marketable cobs. The amount of evapotranspiration fluctuated between 270–440 mm during the five years, depending on the quantity of water supply, but it changed to a lesser extent than the amount of the yield. Increasing the fertilizer dose practically did not affect ET in non-irrigated plants, but increased it by 20–30 mm in irrigated ones. The change was not significant.The productivity of ET was only 30–45 kg ha−1 mm−1 in the non-irrigated treatment, while it was 50–55 kg ha−1 mm−1 in the irrigated treatments, with higher values at the higher fertiliser rates. The productivity of irrigation water exceeded far over the productivity of ET at adequate nutrient supply. The yield increase per 1 mm of irrigation water was on average 60 kg ha−1 mm−1, which was considerably higher than the productivity of ET of non-irrigated plants (39 kg ha−1 mm−1). There was a positive correlation between the yield and ET, and a negative correlation between the yield and specific water consumption. Irrigation and fertilization increased the average yield to a greater extent than evapotranspiration, so as the average yield increased, the ET per unit of yield decreased, i.e. the productivity of evapotranspirated water increased.

Development, optimization and characterization of Enriched noodles

Noodles are one of the staple foods consumed in Nigeria. Wheat, which is a major component in noodles formulation has suffered decline in production in recent times and in addition to this, noodles made from wheat lacks adequate essential nutrient needed for growth considering the awareness that the demography of the population that consumes noodles are mostly children. This study developed and optimized and characterized instant noodles from blends of sweet potato flour, corn flour, and soybean flour. Experiments were conducted using a four-component constrained D-optimal mixture-process experimental design, with thirty-nine (39) randomized experimental runs. The formulation design constraints were: sweet potato flour (10%–61%), soybean flour (5%–20%), corn flour (5%–30%), and water (25%–37%). Other components of the formulation were salt (2.5%), sodium carbonate (0.5%), guar gum (0.5%), and Soy lecithin (0.5%). The processing factors investigated were mixing time (2min - 10min), frying time (1min - 3min), and frying temperature (140 °C–160 °C). The formulated noodles were analyzed and evaluated for the moisture content, crude protein, crude fibre, ash content, crude fat, carbohydrate, energy value, water absorption index, cooking time, cooking weight, bulk density and sensory characteristics, using standard procedures. The result of the formulated noodles optimization gave optimal formulated noodles with overall desirability index of 0.518, based on the set optimization goals and individual quality desirability indices. The optimal noodle was obtained from 23.228% sweet potato flour, 8.815% corn flour, 27.508% soybean flour, 36.449% water, 2.500% salt, 0.500% sodium carbonate, 0.500% guar gum, 0.500% soy lecithin; with 8.169min mixing time, 2.5min frying time, and 144 °C frying temperature. The quality properties of this optimal noodle were 13.654% moisture content, 19.131% crude protein, 5.171% crude fibre, 7.798% ash content, 21.818% crude fat, 32.231% carbohydrate, 32.231 kcal/100g energy value, 109.275 g/g water absorption index, 6min cooking time, 20.928 (% increase in g) cooking weight, 0.645 (g/cubic centimeters) bulk density, and overall acceptability of 6.54, based on 9-point hedonic scale. The result of the study showed that the optimal formulated noodles was of high quality and that improving nutritional quality of noodles is possible through composite formulation. It is recommended that further study be carried out on formulation of nutritionally improved noodles using other nutritionally rich resources. Enrichment of noodles with protein-rich sources will result in noodles with improved nutrient quality that meets the consumer's dietary needs.

Ions Speciation at the Water–Air Interface

In typical aqueous systems, including naturally occurring sweet and salt water and tap water, multiple ion species are co-solvated. At the water-air interface, these ions are known to affect the chemical reactivity, aerosol formation, climate, and water odor. Yet, the composition of ions at the water interface has remained enigmatic. Here, using surface-specific heterodyne-detected sum-frequency generation spectroscopy, we quantify the relative surface activity of two co-solvated ions in solution. We find that more hydrophobic ions are speciated to the interface due to the hydrophilic ions. Quantitative analysis shows that the interfacial hydrophobic ion population increases with decreasing interfacial hydrophilic ion population at the interface. Simulations show that the solvation energy difference between the ions and the intrinsic surface propensity of ions determine the extent of an ion's speciation by other ions. This mechanism provides a unified view of the speciation of monatomic and polyatomic ions at electrolyte solution interfaces.

Statistical Assessment of Sustainable Urban Water Ecosystems

The integrated character of Sustainable Development Goals (SDGs) reflects interconnectedness of water systems and their rich biodiversity, supplying communities with foods, clean water and air, mineral resources, and regulating their welfare and economic growth. The increasing awareness of the importance of public access to water ecosystems can have a positive impact on these ecosystems and encourage partnerships to responsible management of these resources and reactions on water crises through improvements of skills and competencies.&#x0D; The article highlights that the development of partnership relations for the achievement of SDGs is a target 17 of SDGs. An assessment of global and national objectives and indicators laid in the basis of the assessment of a progress on the way to the sustainable environmental accounting and the development of urban water ecosystems is given.&#x0D; It should be noted that the statistical information in divided into four groups which data are used in monitoring of the green economy performance: statistical base of nature assets; environmental and resource productivity of economy; environmental quality of life; economic capabilities and political reactions.&#x0D; The analysis showed the importance of the environmental inclusion of respective spatial groups. Aggregations based on drainage basin or ecosystem can provide better understanding of the environmental dimension of many interconnections defined for sweet water and seawater ecosystems. It is expected, however, that the applicable methods and tools will be elaborated in parallel, to simplify data use by politicians. A deeper understanding of interconnections of SDGs will enable for enhancing the efficiency of political measures. &#x0D; It is concluded that the sustainable development and the 2030 Agenda for Sustainable Development can be achieved only by implementing the overall sectoral approach that will combine the tendencies of the indicators related with the environment with robust policy analysis. This requires the cohesion of all the sustainable development policy dimensions on the basis of the integrated approach, to ensure the elaboration of complementary strategies and to avoid compromises.

Stateless Regionalism and Corporate Power: Willa Cather’s Public Relations Novel

AbstractThis article explores American novelists’ focus on towns or counties (such as Sweet Water, Eatonville, Winesburg, Yoknapatawpha) whether real or imagined, rather than states, and what that might teach us about the novel’s understanding of political totality and democratic action. Novels about towns or counties have been typically conceptualized with the discourse of regionalism, yet that has not led to a literary critical discussion of the federalist system of individual states joined in and as one nation, and how capitalist and corporate power impacts that totality. Focusing on Willa Cather’s novel A Lost Lady (1923), this article develops the notion of “stateless regionalism.” Cather’s novel portrays a political jurisdiction’s complete subsumption by the railroad corporation. Expanding on the town’s fate, the novel portrays the danger of the corporate form—with its attendant incentives, values, and limitations—as it dominates other social, democratic, and political institutions, including municipal town life and, eventually, characters’ sense of self.Cather thus offers us stateless regionalism: the realistic feeling of a political world that does not really function like a political totality at all.

Development of Purple Sweet Potato-Based Ice Cream Product

The popularity of ice cream is increasing in tropical countries such as in Thailand. Purple sweet has high anthocyanin content which provides an attractive purple appearance for ice cream consumption. The purposes of this study were to determine the effects of the ratio of purple sweet potato mash and water, and concentration of carboxymethyl cellulose (CMC) as a stabilizer on the properties of ice cream. The different ratios of purple sweet potato mash and water at 40:60, 50:50, and 60:40 were investigated. The results showed that the ratios of purple sweet potato mash and water had a significant effect (p≤0.05) on physical properties. The overrun, a* and b* values, and melting rate decreased with an increase in purple sweet potato mash. There was a significant (p≤0.05) difference in sensory characteristics scores of appearance, taste, texture, and overall acceptance. The scores decreased with an increase in purple sweet potato mash. Therefore, the selected ratio was 40:60 between purple sweet potato mash and water. In another study, the concentration of CMC at 0.2, 0.3, and 0.4% of total ingredients on the properties of ice cream was observed. The results demonstrated that overrun and melting rates decreased with an increase in CMC. In addition, an increase in CMC showed significantly (p≤0.05) superior taste and texture scores. Therefore, the selected condition for product development of purple sweet potato-based ice cream was the ratio of purple sweet potato mash and water at 40:60 and 0.4%CMC.

Histopathology of Nephrotoxicity Associated with Administered Water Extract Purple Sweet Potato (&lt;i&gt;Ipomoea batatas&lt;/i&gt;) in Mice (&lt;i&gt;Mus musculus&lt;/i&gt;) in Stratified Phases of Dose

The main aim of the registered purple sweet potato (Ipomoea batatas) is to provide minimize the adverse chemical drugs, in addition to its anti-inflammatory, antioxidant, and antimicrobial effects. Potentially adverse effects may be observed in laboratory animals in particular, the extent to which this administration can cause toxicity. This study aimed to examine the histopathology of nephrotoxicity associated with administered water extracts of purple sweet potato in mice with stratified doses. The study was conducted at the Biomedical Laboratory, Faculty of Medicine, Universitas Islam Bandung on September 2019. Female mice (Mus musculus) strain Swiss Webster, aged between 6–8 weeks weighing 25 to 30 g, were obtained from Biopharma Laboratory, Bandung. The animal was acclimatized for seven days before being administered water extract purple sweet potato: eleven mice, one control group, and ten treatment groups underwent toxicity doses of purple sweet potato water extract administration. Purple sweet potato variant of Ayamurasaki prepared in various oral doses. The results show in the control group there were no histopathological changes, but in the group administered water extract purple sweet potato from the first phase seems in a mild grade of macrophage accumulation, mild vacuolization of tubular epithelial cells, mild vascular dilatation, and mild hydrophilic degeneration. In the second phase, macrophage accumulation was visible in moderate grades. The LD50 of purple sweet potato extract is greater than 5,000 mg/kgBW. The findings of this study indicate that registration of purple sweet potato extract in confirmatory doses is safe to administer and did not exhibit any mortality. The toxicity test of purple sweet potato water extracts in the kidney exhibits minimal chemical effects.