You have accessJournal of UrologyCME1 Apr 2023V05-03 CLAMPLESS AND SUTURELESS ROBOT-ASSISTED PARTIAL NEPHRECTOMY FOR THE TREATMENT OF FIFTEEN BILATERAL RENAL LESIONS IN A PATIENT WITH VON HIPPEL-LINDAU SYNDROME Maria Peraire Lores, Jesús Domínguez, Angelo Mottaran, Marco Paciotti, Carlo Bravi, Luca Sarchi, Luigi Nocera, Adele Piro, Rui Farinha, Ruben De Groote, and Alexandre Mottrie Maria Peraire LoresMaria Peraire Lores More articles by this author , Jesús DomínguezJesús Domínguez More articles by this author , Angelo MottaranAngelo Mottaran More articles by this author , Marco PaciottiMarco Paciotti More articles by this author , Carlo BraviCarlo Bravi More articles by this author , Luca SarchiLuca Sarchi More articles by this author , Luigi NoceraLuigi Nocera More articles by this author , Adele PiroAdele Piro More articles by this author , Rui FarinhaRui Farinha More articles by this author , Ruben De GrooteRuben De Groote More articles by this author , and Alexandre MottrieAlexandre Mottrie More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003263.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Patients with Von Hippel-Lindau (VHL) disease have higher risk of developing renal cell carcinomas. In these patients, given the frequent presence of multiple masses and the high risk of recurrence, nephron-sparing approaches are essential to preserve renal function. In this context, technical refinements such as 3D reconstruction, off-clamp, selective suturing or sutureless techniques can be helpful to improve functional outcomes. Herein, we described our surgical management for a patient with VHL syndrome with multiple bilateral renal lesions applying these innovative techniques. METHODS: A 27-year-old man affected by VHL disease presented with 8 and 7 masses on the right and left kidney, respectively. Diameters ranged from 5 to 54 mm on the right, and from 4 on 57 mm on the left. His baseline creatinine was 1.11 mg/dl. First, the patient underwent a left RAPN which revealed 5 clear cell renal cell carcinomas (ccRCC) – the biggest one pT1bR0 – and 2 benign cysts. Six weeks later, the patient underwent a right RAPN. Both procedures were performed using a clampless and sutureless technique; when a completely sutureless resection was not possible, a selective suturing technique was utilised. Preoperative surgical planning included 3-D imaging reconstruction. We here described the surgical procedure for right RAPN and its peri- and post-operative outcomes. RESULTS: Operative and console time were 205 and 175 minutes, respectively. Blood loss was 650 ml. An off-clamp enucleation of all 8 renal masses was performed with a sutureless technique, applying an haemostatic agent (Veriset) to the resection beds. Only for the biggest lower pole mass a selective suture was required in the resection bed. There was no need for intra-operative transfusions, and no perioperative complications occurred. The patient was discharged on the second postoperative day with a creatinine of 0.99 mg/dL. The pathologic assessment revealed 8 ccRCC, the biggest one being pT1bR0. CONCLUSIONS: In patients with multiple renal masses requiring surgical treatment, the use of innovative approaches such as clampless approach, sutureless and/or selective suturing techniques can help preserving healthy parenchyma during RAPN. Further studies with longer functional follow-up are awaited to confirm these findings at long-term. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e424 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Maria Peraire Lores More articles by this author Jesús Domínguez More articles by this author Angelo Mottaran More articles by this author Marco Paciotti More articles by this author Carlo Bravi More articles by this author Luca Sarchi More articles by this author Luigi Nocera More articles by this author Adele Piro More articles by this author Rui Farinha More articles by this author Ruben De Groote More articles by this author Alexandre Mottrie More articles by this author Expand All Advertisement PDF downloadLoading ...
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