Aim of study was to develop bilayer drug delivery for treatment of spasticity by delivering loading and maintenance dose for fast achievement of peak plasma concentration and maintaining the same respectively. The prepared drug loaded bilayer tablets were evaluated for pre and post compression parameters. Stability study of the promising formulation was also performed. The tablets were prepared by direct compression and wet granulation method. The loading dose was delivered in the form of immediate release layer prepared by different super-disintegrations and maintenance dose was delivered through sustained release layer prepared by using polymers like HPMC K4, HPMC K15M, HPMC K100, PEO WSR 303 and Precirol. Both the immediate release layer and sustained release layers were separately optimized and then combined to optimize the bilayertablets. No interactions were found between drug and excipients. Formulation containing Kyron T314 shows immediate drug release. Formulation Containing PEO WSR 303 shows sustained release action and bilayer formulations F6 shows releases up to 24 hours. Bilayer tablets with release characteristics offer critical advantages such as, site specificity with improved absorption and efficacy.Key words: Baclofen, Bilayer tablet, sustain release tablet