This study employs an integration of remote sensing, geographic information systems (GIS), and geophysical techniques to delineate groundwater potential zones (GWPZ). This multidisciplinary approach significantly enhances the precision and reliability of groundwater potential zone mapping. Eight criteria were introduced into the analytic hierarchy process (AHP) to identify GWPZs in Wadi Abu Marzouk by applying a weighted overlay analysis of all criteria layers. The criteria weights were derived by using a pairwise-comparison technique, while the accuracy of the weightage process was calculated by the consistency ratio as 0.06. As revealed in the GWPZ analysis, the northern and northwestern regions have the highest groundwater potentiality. Thirty-five vertical electrical soundings (VES) and four electrical resistivity tomography (ERT) profiles were measured across the study area. The interpretation of geophysical data revealed the presence of a water-bearing layer at depths varying between 27 and 51 m from the ground surface. Its resistivity values indicate the existence of freshwater in the northern and northwestern parts, which highly matches the GWPZ analysis results. However, the southern parts of the area are dominated by saltwater. The integration between geospatial techniques, geophysics, and hydrogeology forms a robust scientific approach, with invaluable insights for sustainable water resource management.