In recent decades, economic and technical advancements have surged tremendously, accompanied by non-regulatory and unsustainable use of non-renewable assets. The ecological field of toxicology has garnered considerable focus on elucidating the impact of harmful substances on people's wellness. Environmental hazardous chemicals induce many illnesses, posing a heightened danger to youngsters, pregnant women, the elderly, and anyone with preexisting health conditions. Air pollution adversely impacts human health, leading to heightened morbidity and death, necessitating intensified toxicological investigations on industrial air pollution affecting the general populace. It is necessary to develop a computerized Ecological Toxicology-based Air Pollution Management System. Constructive social development is driven by cultural education. It can guarantee a sustainable future, protect national history, and unleash community potential. This study examines Chinese architects' perspectives and understanding of sustainability in village revitalization and conservation. It incorporates traditional Lisu building techniques and materials in Hunan, China. To close research gaps, this study looks at the contributions made by architects to traditional practice integration and environmentally conscious architectural design. This study proposes an IoT-enabled Environmental Toxicology platform for air pollution surveillance, utilizing artificial intelligence (AI) techniques to mitigate the limits of standard monitoring systems and lower total costs, enhancing human wellness. The research examined the intricate interaction between architects' understanding of sustainability, Lisu building techniques and materials, and sustainable architectural designs in village preservation and revitalization programs using path analysis on data from 326 architects in Hunan Province. Lisu building practices and materials strongly correlate with architects' awareness of and attitudes toward sustainability. According to the research, these characteristics are necessary for sustainable architectural solutions that support village revival and preservation. This study has significant theoretical and practical ramifications for academics, lawmakers, and architects. To evaluate the air quality monitoring efficacy of the suggested approach, a comprehensive series of simulation analyses is conducted, and the results are assessed at durations of 5, 15, 30, and 60 minutes. The experimental results demonstrate the superior efficacy of the suggested model compared to current methodologies. These findings could lead to the creation of sustainable design solutions that advance rural development. A thorough overview of upcoming studies on sustainable design approaches in Chinese contexts rounds out this talk.