<p>This article explores the integration of Eco Cities and Smart Regions to create sustainable and innovative urban environments. Eco Cities focus on environmental sustainability through renewable energy, waste management, and green infrastructure, aiming to reduce ecological footprints and promote healthy lifestyles. Smart Regions, on the other hand, utilize advanced technologies such as the Internet of Things (IoT), artificial intelligence (AI), and big data analytics to enhance public service efficiency, optimize resource use, and foster economic development. The study highlights how combining these two approaches can lead to significant benefits, including improved operational efficiency, better quality of life, environmental resilience, and active citizen participation. Case studies of cities like Copenhagen and Singapore demonstrate successful integration, showcasing achievements in sustainability and technological innovation. The article also identifies the main challenges in this integration, including technical compatibility, cybersecurity risks, high initial investments, digital inequality, and the need for robust governance frameworks. Overcoming these challenges requires collaborative efforts among governments, private sectors, and civil society, as well as innovative financing strategies and capacity-building programs. Future considerations emphasize the need for a holistic approach to urban planning that incorporates emerging technologies, flexible and adaptive strategies, and inclusive citizen engagement. By addressing these factors, cities and regions can become more resilient, sustainable, and inclusive, meeting the needs of both current and future generations. This integrated approach promises to transform urban environments into hubs of sustainability and innovation, driving long-term positive outcomes for society and the environment.<strong></strong></p>