Human Survival Research Articles

Response and Prediction of Ecosystem Service Values to Land Use Change Resulting from Underground Coal Mining in High Groundwater Table Areas: A Case Study of Jining City, China

Ecosystem services are crucial for human survival and development. Changes in land use can lead to alterations in ecosystem service functions. However, the mechanism of how land use changes resulting from underground coal mining affect ecosystem service remains unclear, especially in areas with high groundwater levels. To address this issue, we studied the spatiotemporal in land use change in Jining City from 2000 to 2020 and employed Markov-PIM (probability integration method)-PLUS (Patch-generate Land Use Simulation) model to simulate land use change and ecosystem service values (ESV) in Jining City by 2030 under four different scenarios. The results indicate that from 2000 to 2020, the area of ecological space increased by 169.99 km2, and the area of living space expanded by 775.28 km2, while the area of production space decreased by 945.27 km2, conversely. These changes led to a 3 million yuan increase in total ESV. From 2020 to 2030, there was a marked decline in ESV under both natural development (ND) and living space preference (LSP) scenarios, with decreases of 0.59 billion yuan and 1.38 billion yuan, respectively. In contrast, in production space preference (PSP) and ecological space preference (ESP) scenarios, ESV increase by 0.22 billion yuan and 0.34 billion yuan. The ESP scenario is an effective strategy to strengthen environmental protection, significantly improve the ESV level of Jining City and meet the development goals of Jining City. Finally, the study concludes with recommendations like comprehensive management, industrial upgrading, and collaborative development for optimizing Jining City's future land use and enhance ESV for urban development.

Determination of Water Quality for Ground Water Near Municipal Dumpsite in Ibadan Southwest Nigeria

Access to clean drinking water is crucial for human health and survival. In vicinities near municipal dumpsites, ensuring groundwater quality is especially vital to safeguard the ecosystem and human health. This study utilized the Entropy Weighted Water Quality Index (EWQI), a novel assessment tool, to evaluate groundwater near the Awotan dumpsite in southwestern Nigeria. Forty-five groundwater samples were collected during rainy and dry seasons and explored for groundwater quality using EWQI. The physicochemical parameters fall within permissible limits for domestic purposes during both seasons. Nonetheless, 2% of the samples surpassed the recommended nitrate limit of 45 mg/L, and all samples had iron levels above the 0.3 mg/L threshold. The calculated EWQI values for these samples ranged from 20 to 528, with 2% deemed excellent, 16% good, 51% medium, 18% poor and 13% extremely poor in terms of water quality for domestic use. The spatial variability in water quality levels means that there are localised impacts of the dumpsite and thus there is need for targeted management strategies. We recommend the government undertake sustainable retrofitting to enhance landfill design, incorporating an efficient leachate collection system to lessen groundwater pollution. Additionally, nearby residents should implement water treatment methods to improve water quality and minimize health risks.

A Review of Exploration and Development Technologies for Coal, Oil, and Natural Gas

Energy is the fundamental prerequisite for human survival and development, as well as the driving force behind the progress of human civilization [...]

Performance Evaluation and Comparison of Deep Neural Network Models for African Soil Properties Prediction

ABSTRACT The significance of soil in agriculture and human survival cannot be overstated. Given its limited supply, improving soil properties is imperative. This study addresses this challenge by predicting five major soil properties—organic carbon, pH values, Mehlich-3 extractable calcium, Mehlich-3 extractable phosphorus, and sand content—utilizing mid-infrared absorbance measurements from the African Soil Information Service (AfSIS) dataset, covering non-desert regions of Africa. With a pressing need for a reliable and efficient model to predict African soil properties using spectral measurements, this study fills a crucial gap, addressing the scarcity of functional soil property databases in Africa. The developed model eliminates costly soil sample preparation and lengthy chemical analysis, applicable in both onsite and laboratory settings for determining soil functional properties. By employing stacked autoencoders for feature dimensionality reduction and combining discrete wavelet transform with two feature selection methods (stepwise regression and random forest) to build robust multi-layer perceptron (MLP) models, the study offers a comprehensive approach. Evaluation metrics including root mean square error (RMSE), scatter index (SI), Variance Accounted For (VAF), Nash-Sutcliffe Model Efficiency (NSE), and Correlation Coefficient (R) demonstrate the superior performance of the MLP model informed by stacked autoencoder-selected features, outperforming models informed by wavelet-transformed features and partial least square regression. This best-performing autoencoder-based model presents a valuable tool for soil scientists tasked with modeling African soil properties.

Next generation plant biostimulants & genome sequencing strategies for sustainable agriculture development

The best environment for plant growth and development contains certain essential metabolites. A broad category of metabolites known as “plant biostimulants” (PBs) includes biomolecules such as proteins, carbohydrates, lipids, and other secondary metabolites related to groups of terpenes, specific nitrogen-containing compounds, and benzene ring-conjugated compounds. The formation of biomolecules depends on both biotic and abiotic factors, such as the release of PB by plants, animals, and microorganisms, or it can result from the control of temperature, humidity, and pressure in the atmosphere, in the case of humic substances (HSs). Understanding the genomic outputs of the concerned organism (may be plants or others than them) becomes crucial for identifying the underlying behaviors that lead to the synthesis of these complex compounds. For the purposes of achieving the objectives of sustainable agriculture, detailed research on PBs is essential because they aid in increasing yield and other growth patterns of agro-economic crops. The regulation of homeostasis in the plant-soil-microbe system for the survival of humans and other animals is mediated by the action of plant biostimulants, as considered essential for the growth of plants. The genomic size and gene operons for functional and regulation control have so far been revealed through technological implementations, but important gene annotations are still lacking, causing a delay in revealing the information. Next-generation sequencing techniques, such as nanopore, nanoball, and Illumina, are essential in troubleshooting the information gaps. These technical advancements have greatly expanded the candidate gene openings. The secondary metabolites being important precursors need to be studied in a much wider scale for accurate calculations of biochemical reactions, taking place inside and outside the synthesized living cell. The present review highlights the sequencing techniques to provide a foundation of opportunity generation for agricultural sustainability.

Neuritin 1 Drives Therapeutic Preservation of Retinal Ganglion Cells in an Ex Vivo Human Glaucoma Model.

Purpose: Glaucoma is a leading cause of irreversible blindness. Glaucomatous intraocular pressure (IOP) triggers deleterious effects, including gliosis, optic nerve (ON) axonal retraction, neurotrophic factor deprivation, inflammation, and other pathological events, leading to retinal ganglion cell (RGC) loss. Trophic factor impairment enhances RGC apoptosis susceptibility. Neuritin 1 (NRN1), a neurotrophic protein downstream of various neurotrophins, exhibited RGC protection and regeneration in axotomy models. We evaluated human recombinant NRN1's impact on human RGCs cultured in pressurized conditions within the ex vivo translaminar autonomous system to simulate glaucoma pathogenesis. Methods: Human glaucomatous and non-glaucomatous donor eyes were obtained from eye banks according to the Declaration of Helsinki. Initially, we evaluated NRN1and RGC marker expression in glaucoma and non-glaucomatous retina to determine the NRN1 level and its association with RGC loss. Further, we evaluated NRN1's therapeutic potential by treating pressurized human eyes at normal and high IOP for seven days. Retina, ON, and conditioned medium were analyzed for RGC survival (THY1, RBPMS), gliosis (GFAP), apoptosis (CASP3, CASP7), and extracellular matrix deposition (COLIV, FN) by qRT-PCR and western blotting. Paraphenylenediamine staining assessed ON axonal degeneration, whereas ex vivo electroretinogram assessed retinal activity. Results: Glaucomatous retinas exhibited significant reductions in both NRN1 (*p = 0.007, n = 5) and RGC marker expression (*p = 0.04, n = 5). NRN1 treatment reduced gliosis, extracellular matrix deposition, ON degeneration, and increased retinal activity in pressure-perfused eyes. Conclusions: Our study confirms that NRN1 enhances human RGC survival and improves retinal function in degenerative conditions, substantiating it as a promising candidate for rescuing human RGCs from degeneration.

Effect of Radical Prostatectomy on Survival for Men with High-risk Nonmetastatic Prostate Cancer Features Selected According to STAMPEDE Criteria: An EMPaCT Study

Background and objectiveA meta-analysis of two randomized STAMPEDE platform trials revealed that 3 yr of abiraterone acetate in addition to androgen deprivation therapy and radiation therapy significantly improved metastasis-free and overall survival (OS) in high-risk nonmetastatic prostate cancer (PCa) and should be considered a new standard of care. The aim of our study was to assess long-term cancer-specific survival (CSS) and OS for surgically treated patients with newly diagnosed nonmetastatic node-negative PCa meeting the STAMPEDE criteria for high risk. MethodsThis was a retrospective, multicenter cohort study of patients with European Association of Urology (EAU) high-risk PCa who underwent radical prostatectomy and extended pelvic lymph node dissection. CSS was assessed using cumulative incidence curves and the Kaplan-Meier method was used to evaluate OS. We used a Fine and Gray model to evaluate the prognostic value of STAMPEDE high-risk factors (SHRFs) for CSS, and a Cox proportional-hazards model to assess the association of SHRFs with OS. Key findings and limitationsA total of 2994 patients with EAU high-risk PCa were divided into groups with 0, 1, 2, or 3 SHRFs. The 10-yr survival estimates for patients with 0–1 versus 2–3 SHRFs were 95% versus 82% for CSS and 81% versus 64% for OS (both p < 0.0001). In comparison to patients with 0 SHRFs, hazard ratios were 1.2 (p = 0.5), 3.9 (p < 0.0001), and 5.5 (p < 0.0001) for CSS, and 1.1 (p = 0.4), 2.2 (p < 0.0001), and 2.5 (p = 0.0004) for OS for patients with 1, 2, and 3 SHRFs, respectively. Conclusions and clinical implicationsOur results confirm that the STAMPEDE high-risk criteria identify a subgroup of patients with highly aggressive PCa features and adverse long-term oncological outcomes. This population is likely to benefit most from aggressive multimodal treatment. Nevertheless, we have shown for the first time that surgery remains a viable treatment option for patients with STAMPEDE high-risk PCa. Patient summaryProstate cancer that meets the high-risk definitions from the STAMPEDE trial is an aggressive type of cancer. Our results for long-term cancer control outcomes indicate that surgery is a viable option for the subgroup of patients with this type of prostate cancer.

The Evolution of Forest Landscape Connectivity and Ecological Network Construction: A Case Study of Zhejiang’s Ecological Corridors

As main components of terrestrial ecosystems, forests play irreplaceable roles in maintaining ecological balance and protecting the basic environment for human survival and development. In this study, the dynamic changes in the forest landscape connectivity in Zhejiang province in 2000, 2010, and 2020 were detected by identifying ecological sources and evaluating connectivity indexes based on morphological spatial analysis (MSPA) and a minimum cumulative resistance (MCR) model. The results are as follows: (1) The forest area of Zhejiang increased by 64.88% from 2000 to 2020, indicating that the overall habitat quality has improved and that ecological risks have decreased, which are attributed to Zhejiang’s adherence to comprehensive environmental management. (2) Regions with low connectivity are distributed mainly in the north, where human activities are intensive. The overall pattern of high connectivity in the middle of the region and low connectivity elsewhere demonstrates the uneven distribution of forest landscape connectivity across the province. (3) The extracted ecological corridors have a mesh-like structure that is dense in the middle and slack in the north. Important corridors have disappeared over time, indicating potential issues in maintaining connectivity for species migration. (4) These results can provide optimization strategies for ecological infrastructure planning in Zhejiang province and offer a theoretical reference for the optimization of the ecological network system.

Solar‐Driven Photoelectrochemical Upcycling of Polyimide Plastic Waste with Safe Green Hydrogen Generation

AbstractArbitrary disposal of plastic waste into landfills and oceans can disturb the ecological system and even challenge human survival. Centralized plastic recycling process only works for selected types of plastics (e.g., polyethylene) with limited contribution (&lt;10%), because of high infrastructure requirement. Comparatively, photoreforming of plastic waste for commodity and fuels production is much more facile and decentralizable, and thus holds great potential to mitigate the plastic waste challenge. To this end, a fully solar powered photoelectrochemical system is developed to selectively upgrade polyimide waste (often appears in electronic waste) into valuable commodity chemicals, including succinic acid, acetic acid, and formic acid, and cogenerating green hydrogen fuels. It is also demonstrated that one of the key monomer, pyromellitic acid, and the precious metals (in electronic waste) can be fully recycled. This proof‐of‐concept demonstration provides a new viewpoint for designing decentralized photoelectrochemical system for simultaneous plastic waste upcycling and renewable fuel synthesis, critical for a sustainable plastic economy. Selective cleavage of benzene ring also opens a green route for other benzene ring‐containing waste upgrading.

O-096 Human fallopian tube organoids provide a favorable environment for sperm motility

Abstract Study question Does a human fallopian tube (HFT) organoid model offer a favorable apical environment for human sperm survival and motility? Summary answer The apical compartment of a new model of human fallopian tube organoids provides after differentiation a favorable environment for sperm motility. What is known already Human fallopian tubes are the site of major events that are crucial for achieving an ongoing pregnancy, such as gamete survival and competence, fertilization steps, and preimplantation embryo development. In order to better understand the tubal physiology and tubal factors involved in these reproductive functions, and to improve still suboptimal in vitro conditions for gametes preparation and embryo culture during In Vitro Fertilization IVF, we sought to develop a human fallopian tube organoid model from isolated adult stem cells allowing spermatozoa coculture in the apical compartment. Study design, size, duration Over a two-year period, fallopian tube tissues were collected for organoid culture purposes from 10 “donor” patients undergoing bilateral salpingectomy by laparoscopy for definitive sterilization. After tissue digestion, adult stem cells from the isthmus and ampulla regions were separately seeded in 3D Matrigel and cultured with conventional growth factors for organoid culture and specific factors for differentiation of the female genital tract. Participants/materials, setting, methods HFT organoids were characterized by light microscopy, scanning and transmission electron microscopy, immunofluorescence and transcriptomic analysis. Following simultaneous organoid culture on specific inserts, spermatozoa from five donors were placed either in control media or in the apical compartment of colon or HFT organoids (isthmus and ampulla separately) for 96 hours. Vitality and motility were assessed at 0, 48, and 96 hours on 200 spermatozoa in each condition and in duplicate and compared using Wilcoxon test. Main results and the role of chance Specific fallopian tube differentiation of our model was confirmed by immunofluorescence, transcriptome analysis and electron microscopy observations that exhibited ciliary and secretory cells. We succeeded in releasing spermatozoa in the apical compartment of HFT organoids and in recovering them for sperm analysis. Sperm vitality values are similar in HFT organoids and in commercial sperm media. We demonstrated a superiority of HFT organoid apical compartment for sperm motility compared with other controls (colon organoids, organoid culture media, and conventional commercial sperm washing and fertilization media). At 48 hours of incubation, progressive sperm motility was higher in the apical compartment of HFT organoids (ampulla 30.6% ±17.3, isthmus 29.3% ±14.8) than in commercial fertilization media (15.3% ±14.6) (p &amp;lt; 0.05) and compared with all other conditions. At 96 hours progressive sperm motility was almost nil (&amp;lt;1%) in all conditions except for spermatozoa within HFT organoids (p &amp;lt; 0.05): 11.5% ±14.7 and 12.9% ±16.9 in ampulla and isthmus organoids, respectively. Limitations, reasons for caution This was an in vitro study in which conditions of organoid culture could not exactly mimic the in vivo environment of extracellular matrix and the vascularization of fallopian tubes. Wider implications of the findings This work opens up perspectives for better understanding of HFT physiology. For the first time, it highlights the possibility of developing HFT organoids for reproductive purposes. In the future, it could help us to improve gametes fertilizing abilities and culture conditions of embryos during human assisted reproductive technologies. Trial registration number not applicable

O-294 Human oocyte survival, early embryo development, metabolic fingerprinting, and pregnancy outcomes following ultra-rapid or standard vitrification and thawing

Abstract Study question Is ultra-rapid vitrification and thawing superior to standard vitrification in terms of preserving oocyte viability, embryo competence and enhancing pregnancy outcomes? Summary answer Ultra-rapid vitrification and thawing preserves oocyte viability and embryo quality as confirmed by their euploidy, non-invasive biomarkers in the culture media, and favorable pregnancy outcomes. What is known already Cryopreservation and vitrification protocols for oocytes and embryos have varying cooling rates, cryoprotectant chemical composition and concentration. While vitrification avoids intracellular ice crystal formation, the elevated concentrations of cryoprotectants may be cytotoxic. Over the past 20 years, parameters for vitrification protocols were optimized to improve efficiency and viability of human oocytes and embryos, however few studies have evaluated the metabolic and secretome profiles in addition to embryology and pregnancy outcomes, particularly following ultra-rapid vitrification and thawing. Mid-infrared spectroscopy is a great option for characterizing environmental components and metabolic profiles using the more spectrally complex fingerprint region from 1450-500 cm-1. Study design, size, duration This prospective study included 1,214 donor oocytes collected between January 2022 and November 2023. Sibling oocytes were assigned to standard or ultra-rapid vitrification and thawing. Corresponding blastocysts underwent the same type of vitrification following trophectoderm biopsies for PGT-A. Spent embryo culture fluid was collected on day 1, 3, and 5 for spectroscopy and PCR analysis, as well as on day 6 for metabolic fingerprinting. Clinical pregnancy was assessed 5 days following single embryo transfer. Participants/materials, setting, methods Vitrified oocyte survival was assessed one hour after thawing. Secretome profiling of day 1, 3, and 5 embryos was conducted by Attenuated Total Reflection Fournier Transform Infrared (ATR-FTIR) spectroscopy. Metabolic profiling of blastocysts (day 6) was conducted by Fournier Transform Infrared (FTIR) spectroscopy. Embryology and pregnancy data together with lipid, protein, and nucleic acid expression profiles were evaluated using the Shapiro-Wilk test followed by the student t-test (parametric variables) or the Mann-Whitney U-Test (non-parametric variables). Main results and the role of chance There was 100% survival in oocytes subject to ultra-rapid vitrification-thawing (n = 531) compared to 94.5% in oocytes that underwent standard vitrification (n = 634). There were no significant differences in the fertilization rates following intracytoplasmic sperm injection (81.3% with ultra-rapid and 83.2% with standard vitrification) or potential to reach day 3 of embryo development[RL1]. Ultra-rapid vitrification-thawing produced significantly more blastocysts than standard vitrification-thawing (67.3% vs. 53.0%, respectively) but both techniques had similar euploidy rates (61.8% vs. 61.4%, respectively; p &amp;gt; 0.05). Spectra in the 4000-450 cm-1 region revealed there were no significant differences in lipid and protein expression profiles of day 1, 3, 5 and 6 embryos. The similar result obtained for the culture media for day 1,3,5 and 6 day embryo development with no significant difference. Day 3 blastomere biopsy samples and Day5, Day 6 trophectoderm biopsy sample showed no significant differences for total protein concentration, lipid and nucleic acid experssion profiles in both group.This finding was corroborated by PCR analysis showing no significant difference in nucleic acid profiles. Finally, clinical pregnancy rates were 65.22% with ultra-rapid and 56.5% [RL2] with standard vitrification. (p &amp;lt; 0.05) Limitations, reasons for caution While both our ultra-rapid and standard vitrification-thawing protocols appear to preserve embryo competence to the blastocyst stage and euploidy, future studies should evaluate whether RNA expression levels are altered with these approaches. Wider implications of the findings This study shows competent and euploid embryos can be generated following ultra-rapid vitrification and provides embryo metabolites that can serve as non-invasive biomarkers for the identification of healthy embryos before embryo transfer. Trial registration number NA

A Comprehensive Examination of the Effects of Climate Change on Maternal, Fetal, and Neonatal Health: An In-Depth Review

The substantial elevation in atmospheric greenhouse gas levels is a consequence of human activities, resulting in a 1.1°C elevation in surface temperature as the worldwide average. The detrimental outcomes of this temperature rise encompass severe weather events, deterioration in food, water, and air quality, alongside an escalation in vector-borne infectious diseases and/or transmission risks. The mitigation and adaptation to climate change are pivotal factors for the survival of humanity in the midst of this existential crisis. Climate change exerts notable effects on maternal, fetal, and neonatal health, with women experiencing more adverse impacts compared to men. Pregnant women may face conditions such as hypertensive disorders like preeclampsia and eclampsia, gestational diabetes mellitus (GDM), variations in pregnancy duration, and mental health disorders. Fetal and newborn health can be affected, leading to results like preterm birth (

Food insecurity, income loss, healthcare access, and other exacerbated social inequalities among people experiencing homelessness during the COVID-19 pandemic in Brazil (2021–2023)

BackgroundDuring COVID-19, the number of people experiencing homelessness increased, further exacerbating the violation of basic rights necessary for human survival. Thus, the study aimed to investigate the inequalities associated with income loss and food insecurity among people experiencing homelessness during the COVID-19 pandemic in Brazil.MethodsA cross-sectional study was conducted in 24 Brazilian state capitals and the Federal District among the homeless population using a validated instrument. Descriptive analyses and binary logistic regressions were performed.ResultsAmong 1512 homeless participants (median age:37, range:18–89), 39.4% had incomplete primary education, 83.7% earned below minimum wage or had no income, 56.5% received government aid, and 87.1% used the Sistema Único de Saúde (Brazilian Public Health System-SUS). During the pandemic, 42.0% faced food difficulties, and 26.3% experienced income loss. Across Brazilian macroregions, lack of employment affected four regions, with high SUS dependency and food scarcity. In the North (72.7%) and Northeast (51.9%), most lacked government aid, while in the Midwest (51.6%), temporary income loss prevailed. In regression analyses, men, black/mixed race, those married or in a stable union, government aid recipients, and SUS users had greater difficulty acquiring food during COVID-19. Men with incomplete high school or higher education and income above minimum wage were less likely to suffer temporary income loss, and black/mixed race individuals and those living on the streets were more likely.ConclusionsThe study showed how socioeconomic factors increased income loss and food acquisition difficulties during COVID-19, exacerbating vulnerability and social inequities for the people experiencing homelessness.

Atypical local and global biological motion perception in children with attention deficit hyperactivity disorder

Perceiving biological motion (BM) is crucial for human survival and social interaction. Many studies have reported impaired BM perception in autism spectrum disorder, which is characterised by deficits in social interaction. Children with attention deficit hyperactivity disorder (ADHD) often exhibit similar difficulties in social interaction. However, few studies have investigated BM perception in children with ADHD. Here, we compared differences in the ability to process local kinematic and global configurational cues, two fundamental abilities of BM perception, between typically developing and ADHD children. We further investigated the relationship between BM perception and social interaction skills measured using the Social Responsiveness Scale and examined the contributions of latent factors (e.g. sex, age, attention, and intelligence) to BM perception. The results revealed that children with ADHD exhibited atypical BM perception. Local and global BM processing showed distinct features. Local BM processing ability was related to social interaction skills, whereas global BM processing ability significantly improved with age. Critically, general BM perception (i.e. both local and global BM processing) may be affected by sustained attentional ability in children with ADHD. This relationship was primarily mediated by reasoning intelligence. These findings elucidate atypical BM perception in ADHD and the latent factors related to BM perception. Moreover, this study provides new evidence that BM perception is a hallmark of social cognition and advances our understanding of the potential roles of local and global processing in BM perception and social cognitive disorders.

Prediction of nitrate, phosphate and ammonia removal in wastewater by phytoremediation-vortex system using artificial neural network

Abstract Clean water is an essential component for human survival. However, the growing global population and the relentless pace of industrial development have resulted in an alarming increase in water contamination. This renders many bodies of water as unfit for consumption or usage. In order to safeguard our natural resources, it is imperative that wastewater should be treated to follow a standard set by environmental specialists. In the Philippines, the enactment of the DAO 2021-19 has updated the requirements for release to more stringent standards. Because of this, a tertiary treatment, such as a phytoremediation bed, can be employed as an additional step in a wastewater treatment process. This study involves a comprehensive approach that consists of a phytoremediation setup, which includes the use of three plant species and specialized soil matrices, and a vortex system. The three plant species, Phragmites australis, Vetiveria zizanioides, and Canna indica are known for their capability for removal of the three pollutants, nitrates, phosphates and ammonia. The phytoremediation-vortex system was able to remove the pollutants and effectively reduce the pollutant concentration that the treated wastewater passes the standards for release. The predictive model, artificial neural network (ANN), was employed to assess the results. By using this technique, the study aimed to not only understand the intricate workings of the vortex system but also to optimise its performance for the effective reduction of pollutants, such as, nitrates, phosphates and ammonia, in wastewater. This research represents a critical step towards developing sustainable and efficient solutions for addressing the pressing challenges posed by water pollution, thereby fostering the availability of clean and potable water for human consumption and various industrial purposes.

Mining Spatial-Temporal Frequent Patterns of Natural Disasters in China Based on Textual Records

Natural disasters pose serious threats to human survival. With global warming, disaster chains related to extreme weather are becoming more common, making it increasingly urgent to understand the relationships between different types of natural disasters. However, there remains a lack of research on the frequent spatial-temporal intervals between different disaster events. In this study, we utilize textual records of natural disaster events to mine frequent spatial-temporal patterns of disasters in China. We first transform the discrete spatial-temporal disaster events into a graph structure. Due to the limit of computing power, we reduce the number of edges in the graph based on domain expertise. We then apply the GraMi frequent subgraph mining algorithm to the spatial-temporal disaster event graph, and the results reveal frequent spatial-temporal intervals between disasters and reflect the spatial-temporal changing pattern of disaster interactions. For example, the pattern of sandstorms happening after gales is mainly concentrated within 50 km and rarely happens at farther spatial distances, and the most common temporal interval is 1 day. The statistical results of this study provide data support for further understanding disaster association patterns and offer decision-making references for disaster prevention efforts.

Старение и надежность: как вариации во времени интенсивности отказов влияют на форму кривых дожития стареющих организмов

The article considers the regularities of the theory of reliability, which determine the constancy of the shape of the curves of organisms’ survival. The assumption that the probability of natural death is determined by the probability of accidental failure of a part of a series of homogeneous elements (cells) allows to obtain, analytically and through numerical experiments, survival curves similar to those observed in nature. The use of com-puter modelling methods makes it possible to identify the survival curve parameters determined by the dynamics of the probability of failure of an individual element. The value of one of these parameters, namely the coordinates of the inflection point of human survival curves, indicates that, apparently, both in long-lived species in general and in humans specifically, the ageing promoting mechanism is the progressive deterioration of reliability - the dilapidation of the elements (cells) crucial for ageing.

Formulation and Evaluation of Herbal Hair Serum

In daily life, there is a rising demand for cosmetics and are used by a large number of individuals annually. Humanity employs a variety of goods to accentuate elegance and attractiveness in order to appear youthful and endearing. Therefore, cosmetics are essential to human survival. Because of the perception that herbal cosmetics are safer and have fewer adverse effects, they are utilized extensively these days. One of the main bodily components that serve as a protective appendage is hair. The spreadability test and stability test results were all assessed. It was the development of a daily-use herbal hair serum is the main objective of this study. To achieve this, a range of herbs will be employed, and the ideal formulation will be determined by evaluating the cosmetic serum’s qualities. Three different cosmetic serum formulations (H1, H2, and H3) with different excipient concentrations have been developed. Physical properties, pH, homogeneity test, and viscosity ensured that every parameter fulfilled the norms and was in good condition. Herbal compositions have been shown to be useful in improving hair consistency.

Formulation and Evaluation of Herbal Hair Serum

In daily life, there is a rising demand for cosmetics and are used by a large number of individuals annually. Humanity employs a variety of goods to accentuate elegance and attractiveness in order to appear youthful and endearing. Therefore, cosmetics are essential to human survival. Because of the perception that herbal cosmetics are safer and have fewer adverse effects, they are utilized extensively these days. One of the main bodily components that serve as a protective appendage is hair. The spreadability test and stability test results were all assessed. It was the development of a daily-use herbal hair serum is the main objective of this study. To achieve this, a range of herbs will be employed, and the ideal formulation will be determined by evaluating the cosmetic serum’s qualities. Three different cosmetic serum formulations (H1, H2, and H3) with different excipient concentrations have been developed. Physical properties, pH, homogeneity test, and viscosity ensured that every parameter fulfilled the norms and was in good condition. Herbal compositions have been shown to be useful in improving hair consistency.

Analisa Manajemen Proyek Pada Pemanfaatan Limbah Stik Es Krim Menjadi Lampu Tidur

This waste used from ice cream sticks will be transformed into a lantern with contemporary aesthetics that can function both as equipment and ornament. The issue of needs and desires, or fulfilling needs, always confronts humanity. Needs are requirements for human survival; among them are economic needs, which are basic needs for society and are therefore met through various work patterns, procedures and strategies. Continuous efforts to meet needs require rational behavior from individuals, which requires action to prevent inefficiency and waste. Conclusion Specific criteria, such as the amount of active components, safety standards, and microbiological test results, are necessary to evaluate tissue quality. It is important to carry out thorough testing at every stage of the production process to guarantee that recyclable containers are of the highest quality.