Surgical Treatment Of Patients Research Articles

Results of Surgical Treatment of Ankle and Posterior Malleolus Fractures Using Different Surgical Techniques

Background. Almost half of the patients with ankle fractures have fracture of the posterior malleolus. Conclusions of the existing studies are contradictory and do not provide a decisive answer to the question of the need for fixation of the posterior tibial fragment.
 Aim of the study — to compare the radiologic and functional outcomes of osteosynthesis of the posterior tibial fragment in unstable ankle fractures using closed reduction and minimally invasive technique and direct open reduction using posterolateral and posteromedial surgical approaches.
 Methods. Prospective multicenter study enrolled 132 patients with complex ankle and posterior malleolus fractures. They were divided into three groups depending on the technique of fixation of posterior tibia. Functional and radiologic results of treatment were assessed at 12, 24, and 48 weeks after osteosynthesis. The AOFAS and Neer scales were used.
 Results. Bone union occurred in all patients at an average of 8.3±0.8 weeks after surgery. Analysis of postoperative CT scans showed that the use of posterior approaches provided statistically significantly more precise reduction of the fragments of posterior tibia. Functional results of patients of the second (posterolateral approach) and third (posteromedial approach) groups at 24 and 48 weeks of follow-up were statistically significantly superior to those of the first group. The median AOFAS score at 48 weeks of follow-up was 86 for group 2 patients and 90 — for group 3. The median scores on the Neer scale were 88 and 94 points respectively.
 Conclusion. Posterior approaches in the surgical treatment of patients with complex ankle and posterior malleolus fractures allow for more precise fragment open reduction compared to closed one. These patients also show better mid-term functional outcomes.

Changes in creatine kinase serum in patient after total hip arthroplasty

Background: Some studies reported that measuring serum creatine kinase (CK) level is an objective method with which to determine the relative invasiveness of surgery. The purpose of this study was to evaluate the change in post-operative serum CK levels as a measure of whether the direct anterior approach (DAA) is less invasive than the posterior approach (PA) regarding postoperative rehabilitation. Methods: This study design was a descriptive research with a qualitative approach, systematic literature review study. ResearchGate, Google Scholar and ScienceDirect searches reviewed changes in serum creatine kinase in patients after total hip arthroplasty. A total of 5 studies conducted between 2019-2023 were included in this review to present a literature review regarding changes in serum creatine kinase in patients after total hip arthroplasty. Results: We analyzed biochemical markers of muscle damage in patients treated with total hip arthroplasty with minimally invasive and standard posterolateral approach to providing objective evidence of the local soft-tissue injury at the time of arthroplasty. A total of 42,890 titles were identified and 5 studies that met the requirements/criteria which discussed changes in serum creatine kinase in patients after total hip arthroplasty. Conclusion: The objective measurement of muscle damage markers provides an unbiased way of determining the immediate effects of surgical intervention in patients treated with total hip arthroplasty.

IMMEDIATE AND LONG-TERM RESULTS OF MINIMALLY INVASIVE AORTIC VALVE REPLACEMENT: SINGLE CENTER RETROSPECTIVE STUDY

HighlightsWe have conducted a retrospective analysis of patients who underwent minimally invasive aortic valve replacement, and evaluated immediate and long-term results of the surgery. AbstractAim. To study the immediate and long-term results of minimally invasive aortic valve (AV) replacement.Methods. The retrospective study included 208 patients with AV stenosis undergoing minimally invasive aortic valve replacement in the period from 2010 to 2019. The ratio of men to women was 1:1. The mean age of the patients was 63 (58–68) years old, with the minimum age being 29 years and the maximum being 81 years. The median follow-up period was 45.5 (11–68) months. Endpoints were as follows: hospital mortality, postoperative complications, long-term outcome (long-term survival, freedom from reoperation). Inclusion criteria were as follows: patients aged 18 years and older undergoing minimally invasive aortic valve replacement. Exclusion criteria were as follows: AVNeo, Ross procedure and AV replacement with aortic homograft, combined interventions (except for intervention on the ascending aorta), and standard access site.Results. The majority of patients (199 (95.7%) underwent “J”-shaped ministernotomy through the III-IV intercostal space. As a part of the combined intervention, ascending aorta replacement was performed in 6 (2.9%) patients. The duration of cardiopulmonary bypass and aortic cross-clamping was 91 (78–106) min and 68 (60–78) min, respectively. Due to conduction disorders, implantation of a pacemaker was performed in 5 (2.4%) patients, stroke was diagnosed in 1 (0.5%) patient, resternotomy for bleeding was performed in 4 (1.9%) patients, cardiac tamponade in 2 (1 %) patients, sternal infection was found in 1 (0.5%) patient. There were no complications such as AKI, perioperative MI, or hospital mortality in any patient. Five- and ten-year survival after surgical treatment of patients was 88.2% and 80.5%, respectively. Five- and ten-year freedom from reoperation on AV was 96.2% and 96.2%.Conclusions. Minimally invasive AV replacement is a measurable procedure with negligible complication rates. Minimally invasive aortic valve replacement has shown its effectiveness in the long-term period with acceptable rates of survival and freedom from reoperation.

The results of diagnosis and surgical treatment of patients with neuroendocrine tumors of the small intestine

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Comparative Assessment of Surgical Treatment Outcomes in Patients with Sacroiliac Joint Injury

stract The aim of the study is to evaluate the results of surgical treatment in patients with sacroiliac joint injury. Methods. An analysis of the results of surgical treatment of 60 patients with sacroiliac joint injury was conducted at the Center of polytrauma and orthopedic surgery of the State Public Healthcare Institution “Emergency Hospital” in Abai Region, the Trauma and Endoprosthetics Department of the State Public Healthcare Institution “Multispecialty City Hospital No. 1” in the city of Astana, and the “Shymkent City Clinical Hospital No. 1” from June 2019 to August 2022. Patients were divided into two groups. Patients in the control group underwent surgery using the standard technique, while patients in the experimental group underwent surgery using a device developed by us for minimally invasive locking osteosynthesis of sacroiliac joint injuries. The study was a randomized controlled trial by design. Results. The use of the device for minimally invasive locking osteosynthesis of sacroiliac joint injuries leads to a significant reduction in the length of hospitalization for all types of sacroiliac joint injuries regardless of the patient’s initial condition (p=0.001). Correlation analysis revealed a correlation between the observation group and patient pain assessment at 12 months (p=0.001). According to the Majeed Pelvic Score at 12 months, the maximum score in the experimental group was 98 points, while in the control group, it was 70 points. A satisfactory assessment on the Majeed Pelvic Score at 12 months was observed in 3 (10%) of patients in the control group and none in the experimental group. There were no unsatisfactory responses in both groups (significant differences were found, p=0.001). Conclusions. The use of the device developed by us for minimally invasive locking osteosynthesis of sacroiliac joint injuries reduces the length of hospitalization and the time to return to work (12 months in the control group and 8 months in the experimental group). The absence of pain in patients after 12 months in the experimental group was 26 (86.7%) and 20 (66.6%) in the control group. According to the Majeed Pelvic Score in the long term (3, 6, and 12 months), the frequency of excellent results increases from 13.3% to 90.0% in the experimental group and from 10% to 73.4% in the control group.

The risk factors for miscarriage of viable intrauterine pregnancies in patients with heterotopic pregnancy after surgical intervention.

To summarize the clinical characteristics and explore the risk factors for miscarriage of a viable intrauterine pregnancy following surgical intervention in patients with heterotopic pregnancy (HP). A total of 106 women diagnosed with HP that underwent surgical intervention in the Women's Hospital School of Medicine Zhejiang University between January 2014 and December 2021 were included in this retrospective study. They were divided into a miscarriage group (n = 13) and an ongoing pregnancy group (n = 93) according to the outcomes of the HP within 2 weeks after surgery. Data regarding clinical characteristics, surgical conditions, postoperative recovery, and complications were collected and compared between the groups. Logistic multivariate analysis was performed to explore the risk factors for miscarriage in patients with HP within 2 weeks of surgical intervention. Among the 106 women with HP, 80 had tubal HP, 8 had cornual HP, and 18 had interstitial HP. Eighty-seven (82.1%) patients developed clinical symptoms that manifested primarily as abnormal vaginal bleeding and/or abdominal pain, whereas 19 (17.9%) patients had no clinical symptoms. The mean gestational age on the day of surgery was 7.2 weeks (inter-quartile range, 6.4-8.3). The miscarriage rate within 2 weeks of surgical intervention was 12.3% in patients with HP. Compared to the ongoing pregnancy group, the miscarriage group had a higher body mass index, earlier gestational age at treatment, and higher volume of hemoperitoneum (P < .05 for all). Logistic multivariate analysis indicated that the women with a hemoperitoneum volume > 200 mL had significantly higher risk of miscarriage after adjusting covariates [OR (odds ratio) = 5.285, 95% CI (confidence interval) (1.152-24.238), P < .05]. Hemoperitoneum volume was independently associated with miscarriage of viable intrauterine pregnancies in patients with HP within 2 weeks of surgical intervention.

CHARACTERISTICS OF ACQUIRED OBSTRUCTION OF LACRIMAL PATHWAYS IN PATIENTS WITH CHRONIC TYPE 2 DIABETES AND COMBINED CONSERVATIVE AND SURGICAL TREATMENT INVOLVING ENT SPECIALISTS

Pathological changes in the lacrimal system such as dry eye syndrome in patients with diabetes are well described in modern literature, but no sufficient attention is paid to the problem of the lacrimal system in this group of patients. Currently, the established protocol for treating chronic dacryocystitis involves collaborative endoscopic endonasal dacryocystorhinostomy conducted by ophthalmic surgeons and ENT specialists. However, in patients with type 2 diabetes, there is a need to investigate the clinical effectiveness of this surgical approach.&#x0D; Purpose of this study is to evaluate the effectiveness of conservative and surgical treatment in patients with chronic dacryocystitis depending on the presence of type 2 diabetes and to determine the features of the postoperative period.&#x0D; Materials and methods. The study included 30 patients with chronic dacryocystitis and type 2 diabetes (main group) and 30 patients with chronic dacryocystitis without diabetes (control group), who underwent endoscopic endonasal dacryocystorhinostomy according to the standard technique. The results of the operation were evaluated in 2 months, 6 months and 2 years following the surgical interventions.&#x0D; Endoscopic endonasal dacryocystorhinostomy was considered as an effective technique for restoring unobstructed lacrimal drainage when it lead to the alleviation of tearing, and preventing re-infection of the lacrimal sac. Alongside conventional ophthalmological examinations, the assessment involved nasopharyngeal and lacrimal suction tests, reflux tests, lacrimal duct lavage, lacrimal canal probing, computer tomography, and endoscopic examination of the nasal cavity.&#x0D; Results and discussion. The effectiveness of surgical treatment in 2 months after the operation in patients of the main group (70% of patients) was 1.3 times, after 6 months (63.3% of patients) was 1.4 times, and in the remote period in 2 years (50% of patients) was 1.6 times lower than in patients of the control group (р&lt;0.05). Analyzing the presence of the main symptoms of chronic dacryocystitis in the dynamics of observation, it was noted that after endoscopic endonasal dacryocystorhinostomy the most frequent symptom was lacrimation, but its frequency in patients of the main group after 2 months (30% of patients) was 4.5 times, after 6 months (36.7% of patients) - 2.8 times, after 2 years (50% of patients) - 2.5 times higher than in patients of the control group (р&lt;0.05 ).&#x0D; The efficacy of surgical treatment's in 2 month following the operation in the main group patients (70%) was 1.3 times, after 6 months (63.3%) was 1.4 times, and in the long-term, 2 years post-operation (50%), was 1.6 times lower than in the control group patients (p&lt;0.05). Analyzing the dynamics of chronic dacryocystitis symptoms during observation, it was observed that following endoscopic endonasal dacryocystorhinostomy, lacrimation emerged as the most common symptom. However, its frequency in the main group patients was notably higher after 2 months (30%), being 4.5 times, after 6 months (36.7%) it was 2.8 times higher, and after 2 years (50%) it was 2.5 times higher compared to the control group (p&lt;0.05).&#x0D; Conclusions. In patients with type 2 diabetes, the clinical effectiveness of conservative and surgical treatment for chronic dacryocystitis is lower than in patients without diabetes, and the postoperative period has its own characteristics.

COMPARATIVE ANALYSIS OF CONSERVATIVE AND SURGICAL TREATMENT OUTCOMES IN PATIENTS WITH DIAPHYSEAL HUMERUS FRACTURES

The frequency of diaphyseal humerus fractures varies from 1% to 5% of the total number of skeletal fractures in humans. A clear bimodal gender and age distribution of patients with fractures in the studied area has been established. The main methods of treatment for closed intra-articular humerus fractures are conservative functional and surgical treatment. Treatment of diaphyseal humerus trauma involves not only restoring the axis and length of the bone but also ensuring sufficient mobility of adjacent joints. The aim of the study was to conduct a comparative analysis of the outcomes of conservative and surgical treatment in patients with diaphyseal humerus fractures. The study involved 57 patients with diaphyseal humerus fractures aged from 19 to 83 years. The first clinical group comprised of 24 patients aged from 24 to 80 years who were treated using functional fixation devices. The second clinical group consisted of 33 patients aged from 19 to 83 years who were treated using surgical techniques, namely antegrade locked intramedullary nailing and cortical plate and screw osteosynthesis. Rehabilitation measures were initiated within the first two days for patients in the first group and in the early postoperative period for patients in the second group. The range of motion of adjacent joints was assessed using the CMS and MEPS scales. The use of surgical treatment techniques in combination with early rehabilitation measures, compared to conservative functional treatment, allows achieving significantly higher and statistically significant (p&lt;=0.01) functional outcomes of elbow joint mobility.

SIGNIFICANCE OF CHOOSING FIXATORS FOR OSTEOSYNTHESIS IN THE TREATMENT OF PATIENTS WITH FRACTURES OF PROXIMAL FEMORAL PART

Introduction. Fracture of the proximal part of the femur is one of the most common and most life-threatening injuries in the elderly patients. At the current stage, the surgical method has taken the leading place in the treatment of these patients. The growing number of surgical interventions, along with the increase in the elderly population globally, has led to a corresponding increase in the number of complications related to both the biological and mechanical properties of the fixator used. The optimal location of the fixing elements in relation to the center and edge of the femoral head, the value of the cervical-diaphyseal angle, and the technical characteristics of the implants remains a relevant issue today.&#x0D; The purpose of this study was to analyze the cause of complications after surgical treatment in patients with fractures of the femoral proximal part taking into account the biomechanical properties of the fixators.&#x0D; Material and methods. Staged results of surgical treatment of 60 patients with fractures of the proximal part of the thigh, who were hospitalized due to complications related to imperfect mechanical fixation of bone fractures, were studied. Patients were divided into 2 groups depending on the type of fixator used.&#x0D; Results. Migration of fixators with a low level of stability occurs even with the initial correct placement of the implant. Notably, a relatively higher frequency of migration occurred when the fixator was applied to the left limb (23:37). Analysis of immediate post-implantation frontal and axial radiographs revealed that, in all instances of medial migration (cutout effect) and lateral migration (outout effect), the Tip-Apex Distance exceeded 25 mm. The positioning of the cervical component of the fixator did not align with its optimal placement as per the Cleveland zones in 84.6% of cases. A notable incidence of complications in extramedullary osteosynthesis was diagnosed during the early postoperative period. This observation may be attributed to an imperfect plan of the staged rehabilitation functional regime.&#x0D; Conclusions. The use of fixators with a low level of stability does not provide high-quality prediction of the course of the postoperative period in patients with femoral proximal fractures. Placing implants for osteosynthesis of the femoral proximal part should ensure reliable fixation of fragments for successful postoperative rehabilitation by taking into account the number of fixators and the features of their location in the proximal fragment of the fracture.

Surgical Treatment of Patients with Damage to the Ligaments Holding the Long Head of the Biceps (Pulley Lesion) in Combination with Contracture of the Shoulder Joint

Background. Damage to the ligaments holding the long head of the biceps, or Pulley Lesion injuries, are often accompanied by contracture of the shoulder joint.&#x0D; Objective. The objective of the study was to compare the treatment outcomes of patients with Pulley Lesion injuries and secondary adhesive capsulitis.&#x0D; Material and Methods. The study included 82 patients with contracture of the shoulder joint and damage to the ligaments holding the long head of the biceps. The patients were divided into 2 groups depending on the extent of surgical intervention: group 1 underwent subpectoral tenodesis and selective capsulotomy of the shoulder joint; group 2 underwent subpectoral tenodesis without selective capsulotomy of the shoulder joint. The function of the shoulder joint was assessed using the Constant Shoulder Score and VAS scales before surgery, at 3 and 6 months after the surgery.&#x0D; Results. At 3 months follow-up, the average functional result according to the Constant Shoulder Score was somewhat worse in group 2 (14.5±5.2 points) than in group 1 (8.5±6.4 points), p = 0.031. At 6 months follow-up, the average functional result according to the Constant Shoulder Score was 5.1±5.6 points in group 1 and 10.1±4.1 points in group 2 (p = 0.024). At 3 months follow-up, the average VAS score was worse in group 2 than in group 1 and reached 2.81±0.7 points. At 6 months follow-up, the average VAS score in group 2 was also worse than in group 1 (p = 0.051).&#x0D; Conclusions. Performing selective capsulotomy and subpectoral tenodesis in patients with secondary adhesive capsulitis and damage to the ligaments holding the long head of the biceps (Pulley Lesion injuries) allows us to achieve better functional results both according to the Constant Shoulder Score and the VAS scale at 3 and 6 months after the surgery.

Clinical Outcomes After Traumatic Brain Injury and Exposure to Extracranial Surgery

Traumatic brain injury (TBI) is associated with persistent functional and cognitive deficits, which may be susceptible to secondary insults. The implications of exposure to surgery and anesthesia after TBI warrant investigation, given that surgery has been associated with neurocognitive disorders. To examine whether exposure to extracranial (EC) surgery and anesthesia is related to worse functional and cognitive outcomes after TBI. This study was a retrospective, secondary analysis of data from the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study, a prospective cohort study that assessed longitudinal outcomes of participants enrolled at 18 level I US trauma centers between February 1, 2014, and August 31, 2018. Participants were 17 years or older, presented within 24 hours of trauma, were admitted to an inpatient unit from the emergency department, had known Glasgow Coma Scale (GCS) and head computed tomography (CT) status, and did not undergo cranial surgery. This analysis was conducted between January 2, 2020, and August 8, 2023. Participants who underwent EC surgery during the index admission were compared with participants with no surgery in groups with a peripheral orthopedic injury or a TBI and were classified as having uncomplicated mild TBI (GCS score of 13-15 and negative CT results [CT- mTBI]), complicated mild TBI (GCS score of 13-15 and positive CT results [CT+ mTBI]), or moderate to severe TBI (GCS score of 3-12 [m/sTBI]). The primary outcomes were functional limitations quantified by the Glasgow Outcome Scale-Extended for all injuries (GOSE-ALL) and brain injury (GOSE-TBI) and neurocognitive outcomes at 2 weeks and 6 months after injury. A total of 1835 participants (mean [SD] age, 42.2 [17.8] years; 1279 [70%] male; 299 Black, 1412 White, and 96 other) were analyzed, including 1349 nonsurgical participants and 486 participants undergoing EC surgery. The participants undergoing EC surgery across all TBI severities had significantly worse GOSE-ALL scores at 2 weeks and 6 months compared with their nonsurgical counterparts. At 6 months after injury, m/sTBI and CT+ mTBI participants who underwent EC surgery had significantly worse GOSE-TBI scores (B = -1.11 [95% CI, -1.53 to -0.68] in participants with m/sTBI and -0.39 [95% CI, -0.77 to -0.01] in participants with CT+ mTBI) and performed worse on the Trail Making Test Part B (B = 30.1 [95% CI, 11.9-48.2] in participants with m/sTBI and 26.3 [95% CI, 11.3-41.2] in participants with CT+ mTBI). This study found that exposure to EC surgery and anesthesia was associated with adverse functional outcomes and impaired executive function after TBI. This unfavorable association warrants further investigation of the potential mechanisms and clinical implications that could inform decisions regarding the timing of surgical interventions in patients after TBI.

Logistics of technologies in the framework of personalized rehabilitation of patients with chronic back pain

BACKGROUND: Lower back pain covers a large part of the population and is common in all age groups. Scientific research shows not only significant medical and social, but also high economic costs associated with this problem.&#x0D; AIM: optimization of diagnostic and rehabilitation approaches in the management of patients with chronic back pain.&#x0D; MATERIALS AND METHODS: 126 patients participated in the ongoing single-center prospective cohort study. The assessment of neuroorthopedic examination and neuropsychological status, laboratory, neuroimaging (magnetic resonance tomography) and neurophysiological studies of patients, filling out scales and questionnaires, consultations of related specialists were carried out. 42 patients with a clinical picture of neuropathic pain underwent electromyography stimulation, and 16 of them underwent a transcranial magnetic stimulation study. Within the framework of the pilot project, 22 patients with identified undesirable side reactions when taking non-steroidal anti-inflammatory drugss underwent pharmacogenetic research and consulting by a medical geneticist to select personalized non-steroidal anti-inflammatory drugs pharmacotherapy. Based on the results of the examinations, taking into account the nature of the course of the disease and the prevailing pathogenetic variant of pain, an individual rehabilitation program was developed. To assess the individual rehabilitation program, the data obtained within each group were compared with the results of treatment of patients with the traditional approach (retrospective analysis of medical histories).&#x0D; RESULTS: The study included 126 patients (67 men and 59 women) with lower back pain persisting for more than 3 months. The average age was 50.06±1.25 years. The average duration of the disease was 10±2.19 months. The patients were divided into 3 groups: the first group of 30 patients with back pain and the predominance of a dysfunctional component; the second group of 78 patients with neuropathic pain syndrome (radiculopathy); the third group included 18 patients with nociceptive variant of back pain. As a result of the pathogenetically directed rehabilitation program, it was possible to increase patients' adherence to treatment and compliance with recommendations (p 0.05) and reduce the need for surgical treatment in patients with discogenic radicular syndrome (p 0.05).&#x0D; CONCLUSION: The multi-vector multidisciplinary approach with a pathogenetic focus on identifying and treating clinical and pathogenetic variants of pain and the causes of its persistence is the most effective, and physical rehabilitation methods are well combined with each other and with pharmacotherapy, potentiating each other's effects.

Carotid Imaging in 2023: Stenosis and Beyond

In the last two decades, significant advances have been made in the further understanding of carotid atherosclerosis and stroke risk. While currently practical stratification regarding a surgical intervention in patients with symptomatic carotid disease is made based on the degree of luminal narrowing, several plaque features have been identified as independent risk factors for the development of downstream ischaemic events. Several of these plaque features can be readily identified on routine CT- and MR-examinations, and will be discussed during this lecture. Consequently, a contemporary radiology report must go beyond a mere description of the presence and degree of luminal narrowing, and must also provide information on plaque morphology and other vessel wall characteristics. This comprehensive approach will enable the referring clinical to better stratify their patients regarding current and future risk, leading to better patient management and clinical outcomes.

Surgical treatment of patients with shoulder joint stiffness and injury to the glenoid labrum

Background. Most of our colleagues, upon discovering injuries to the glenoid labrum or other soft tissue structures of the shoulder joint in a patient, perform surgical interventions without paying attention to changes in its capsule. Objective: to compare the treatment outcomes of patients with shoulder contracture who underwent arthroscopic capsular release with re-fixation of the glenoid labrum versus those who underwent only re-fixation of the glenoid labrum.&#x0D; Materials and methods: The study included 98 patients with shoulder joint stiffness and glenoid labrum injury. The patients were divided into two groups: group 1 underwent re-fixation of the glenoid labrum and arthroscopic capsular release, while group 2 underwent re-fixation of the glenoid labrum without arthroscopic capsular release.&#x0D; Results: Three months after the operation, in group 2, the mean functional outcome according to the Constant Shoulder Score scale was slightly worse than in group 1 and ranged from 14.5 ± 6.2 points, while in group 1, the mean functional outcome was 8.5 ± 6 points (p = 0.031). Six months after the operation, in group 1, the mean functional outcome according to the Constant Shoulder Score scale was 5.1 ± 5.6 points, while in group 2, it was 10.1 ± 4.1 points (p = 0.024). Conclusion: The results of treating patients with secondary shoulder stiffness who underwent arthroscopic capsular release and fixation of the glenoid labrum were better according to the Constant Shoulder Score and the VAS scale at both 3 and 6 months after the operation than the results of treating patients who underwent only fixation of the glenoid labrum without arthroscopic capsular release.

Clinical predictors and surgical outcomes following surgical treatment in patients with cervical spondylotic myelopathy, Addis Ababa, Ethiopia: A prospective study

BackgroundCSM is the most common cause of spinal dysfunction in adults older than 55 years of age and surgery is the mainstay of treatment for patients with CSM.The objective of our study was to assess the outcome of patients operated for CSM by using m-JOA and Recovery rate using Hirabayashi formula and evaluate clinical factors predicting surgical outcomes in patients undergoing decompressive surgeries. MethodologyAdult CSM patients fulfilling inclusion and exclusion criteria were enrolled at two hospitals. Patients were followed prospectively for a minimum of 06 month, with mJOA score, recovery rate (using Hirabayashi formula) and Postoperative complications assessments. Possible clinical predictive factors were also assessed. ResultsThere were 38 men and 19 women (mean age, 50.63 yr) enrolled in our study. 48 patients had anterior cervical procedure, 9 patients had posterior procedures.The mean mJOA scores at 6 months (13.33) and 1 year(14.74) after surgery were significantly higher than the mean preoperative mJOA (10.44) (P value = 0.01). 42(73.4 %)patients had recovery, 7 patients (11.9 %) remained the same while 8 (13.6 %) patients worsened. Average recovery rate was 36.59 ± 37.12 % in younger patients(<65yrs) and 2.4 ± 47.10 % in the group older than 65 years (P value = 0.043). Rate of recovery in patients with symptom duration of < 1 year was found to be better than those presented with symptom duration of > 1 year(39.11 % vs 15.54 %) with p-value = 0.035. Six patients had new neurologic deficit in the immediate postoperative period. ConclusionsSurgical treatment of CSM was associated with significant improvement in mJOA and recovery rate at 6 and 12 months. Age and duration of symptom were highly predictive of surgical. Our study showed a high rate of immediate post op neurologic deterioration but other complications in our study were comparable with those in previously reported CSM series.

Alveolar Bone Grafting in Unilateral Cleft Lip and Palate: Impact of Timing on Palatal Shape.

Alveolar bone grafting (ABG) is a critical surgical intervention in patients with a cleft of the alveolus, aimed at reconstructing the alveolar ridge to facilitate proper eruption, periodontal support, and alignment of adjacent permanent teeth. The optimal timing for ABG remains debated, with late secondary ABG between the ages of 9 and 11 being widely adopted. This study compared the palatal shapes of 28 children at a mean age of 9.5 years (SD = 0.7) who underwent early secondary ABG at a mean age of 2.1 years (SD = 0.6) or 33 children at a mean age of 10.8 years (SD = 1.5) who underwent late secondary ABG at a mean age of 8.6 years (SD = 1.3) to 60 non-cleft controls at a mean age of 8.6 years (SD = 1.2). The palatal shapes were captured with 239 landmarks digitized on the palate on a digital model. Utilizing geometric morphometric methods, i.e., generalized Procrustes superimpositions, principal component analysis, and permutation tests, we assessed the impact of ABG timing on palatal morphology. The first five principal components (PCs) explained 64.1% of the total shape variability: PC1 = 26.1%; PC2 = 12%; PC3 = 11.9%; PC4 = 7.8%; and PC5 = 6.4%. The Procrustes distance between both cleft groups and the control group was more than twice as large as the Procrustes distance between the early ABG and late ABG groups. Nonetheless, all intergroup differences were statistically significant. Our findings suggest that early ABG has a limited negative effect on palatal shape, providing comparable outcomes to late ABG. The study highlights the potential suitability of early ABG, challenging conventional practices and encouraging further exploration into its long-term effects on maxillary growth.

Comparative study of trimming and resection of diseased finger superficial flexor tendons in gouty carpal tunnel syndrome

BackgroundHyperuricemia can lead to synovial hyperplasia in the wrist. In severe cases, it can lead to the deposition of gouty stone in the carpal tunnel, resulting in increased pressure in the carpal tunnel and compression of the median nerve to cause carpal tunnel syndrome (CTS), which is called gouty carpal tunnel syndrome (GCTS). As for the surgical treatment of gouty carpal tunnel syndrome, scholars have different opinions on whether it is necessary to remove the superficial flexor tendon. The purpose of this study was to compare the clinical efficacy of trimming and resection of the diseased superficial flexor tendon in the treatment of gouty carpal tunnel syndrome.MethodsClinical data were collected from May 2016 to July 2021 from 10 patients (13 affected wrists) diagnosed with gouty carpal tunnel syndrome and classified into two groups according to the surgical modality: the diseased portion of the gout-eroded superficial finger tendon was trimmed in 9 wrists, and the diseased superficial finger flexor tendon was excised in 4 wrists. Values related to flexion and extension functions, 2-PD, DASH, BCTQ, VAS and recurrence in the affected fingers were compared between the two groups as well as before and after surgery in each group.ResultsAll affected limbs used were cleared of gouty stones, finger numbness improved, no skin necrosis occurred, and all incisions healed at stage I. At follow-up (13.58 ± 5.53 months), there was no significant difference between groups in flexion and extension function, 2-PD, DASH, BCTQ, and VAS with respect to the affected fingers, and patients in both groups improved significantly before and after surgery. Treatment of only one wrist involved trimming to remove lesion-affected portions of tendon, which reappeared 1 year after surgery, and there was one case of poor recovery from greater piriformis muscle atrophy in both procedures.ConclusionRegarding surgical treatment of patients with gouty carpal tunnel syndrome in which the gouty stone has invaded the superficial flexor tendons of the fingers, the diseased superficial flexor tendons can be selectively excised, and the postoperative mobility of the affected fingers may not be impaired.

The challenges and the particulars surgical treatment of breast cancer associated with pregnancy

In the conditions of the decentralization of the Oncology Service, the problem of breast cancer associated with pregnancy remains a clinical, medico-social, surgical, but also complex problem, at the intersection between the scientific and practical-oncological disciplines, obstetrics and gynecology and specialized surgery, which also imposes many challenges, in the world the cases of breast cancer associated with pregnancy increase annually. About 4% of breast cancers are associated with pregnancy, and require solving both the pregnancy and the complex and combined and primarily surgical treatment. Namely, multiple problems and challenges are imposed on this department, as well as specific peculiarities of both general, oncological and obstetric surgery. For the first time, a survey of general surgeons, mammological oncologists and specialists in obstetrics and gynecology was carried out to initiate specialized research in this field.The challenges and particularities of surgical treatment in patients with breast cancer were established through questionnaires, in-depth interviews and focus groups and scientifically highlighted hierarchically.

Surgical Treatment for Patients with Post-traumatic Flexion Contracture of Proximal Interphalangeal Joint: Analysis of Various Affecting Factors.

Background: A flexion contracture (FC) of the proximal interphalangeal (PIP) joint can have a profound negative influence on daily activity. The outcomes of surgical release of the PIP joint in literature are based on small sample size studies done several decades ago. The aim of this study is to report the outcomes of surgical treatment for post-traumatic FC of the PIP joint and to identify factors that affect these outcomes. Methods: This single institute retrospective study included patients from 2000 to 2020. We only included patients with post-traumatic FC of the PIP joint. We evaluated the demographic characteristics, cause of FC, surgical approaches and the various procedures conducted. We surveyed postoperative complications. During the study period, we asked about their current symptoms and evaluated their operative outcomes as excellent, good, fair or poor through the phone. Results: The average FC recovery angle was 37.3°. The small finger was the most affected, and the most common cause of FC was a tendon laceration. The volar plate complex release was the most frequently conducted procedure. The FC improvement was positively correlated to the degree of preoperative FC. The more severe preoperative flexion-extension arc was presented, the more FC recovery was achieved after operation. Patients who underwent multiple procedures had a higher degree of preoperative FC, and better correction was achieved with multiple procedures than with a single procedure. The most critical complication was recurrence. Conclusions: We were able to obtain average 37.3° of extension by surgical treatment. The more severe the FC presented before surgery, the greater the need for multiple procedures, however, this resulted in a significant increase in joint extension. Nevertheless, caution should be exercised regarding recurrence and could occur even with an experienced surgeon. Level of Evidence: Level IV (Therapeutic).

OP04 The Efficacy Of Segmentectomy And Lobectomy For Non-Small Cell Lung Cancer: A Systematic Review And Meta-Analysis

IntroductionThe latest clinical practice guidelines for non-small cell lung cancer (NSCLC) published by the National Comprehensive Cancer Network in 2022 recommend that patients with NSCLC (&gt;1 and ≤2 cm) should be diagnosed as T1b. Segmentectomy and lobectomy are equally effective in treating patients with NSCLC no bigger than 2 cm, and especially for tumors no bigger than 1 cm. However, the effectiveness of these treatments for NSCLC tumors between 1 and 2 cm is unknown. We conducted a systemic review and meta- analysis to assess the efficacy of these two surgical treatments in patients with T1b stage NSCLC.MethodsWe searched for randomized controlled trials (RCTs) and cohort studies investigating the efficacy of lobectomy and segmentectomy for patients with T1b stage NSCLC. Study quality was assessed with the Cochrane Quality in Prognosis Studies tool. We used random effects models to analyze overall survival (OS) and lung cancer-specific survival (LCSS), expressed as hazard ratios (HR) and 95% confidence intervals (CIs). The effect of covariates was assessed using subgroup analysis. All procedures were performed according to the PRISMA guidelines.ResultsWe identified ten cohort studies that matched our selection criteria, with general low risk of quality, including a total of 37,691 patients. No publication bias was found. Compared to lobectomy, segmentectomy had lower OS (HR 1.31, 95% CI: 1.16, 1.47; p=0.026) and LCSS (HR 1.21, 95% CI: 1.03, 1.42, p=0.015) before Cox regression. After multivariable Cox regression, adjusted by age, sex, histological type, and lymph node section, segmentectomy had similar OS (HR 1.17, 95% CI: 1.00, 1.37; p=0.2) and LCSS (HR 1.10, 95% CI: 0.89, 1.36; p=0.8).ConclusionsSegmentectomy can be used to treat patients with T1b stage NSCLC. Patients who undergo segmentectomy have survival outcomes that are the same as those of patients who received lobectomy. This evidence-based observation provides a reference for surgical choice in the treatment of patients with T1b stage NSCLC, which should be further confirmed through RCTs.