Surgical Management Of Patients Research Articles

Going with the flow: Implementing a 4D flow MRI program at a children's hospital.

Four-dimensional phase contrast MRI (4D flow) has emerged as a versatile imaging technique for comprehensive visualization and both qualitative and quantitative assessment of cardiovascular blood flow. 4D flow is a three-dimensional, time-resolved acquisition that is gated to the cardiac cycle. 4D flow provides cardiovascular velocity and flow assessment across the volume of acquisition and yields a multitude of advanced hemodynamic parameters that help to assess the impact of cardiovascular disease on flow and vice versa, guiding the clinical and surgical management of patients with congenital and acquired heart disease. In the past, lengthy scan acquisition and complex post-processing workflows hindered 4D flow adoption into routine clinical practice. Decreasing image acquisition times and improvements in post-processing techniques have made 4D flow a clinically useful tool. The purpose of this communication is to facilitate more widespread adoption of 4D flow by describing its clinical utility, technical acquisition, optimization, and post-processing in pediatric cardiovascular imaging at our center.

TIPS AND TRICKS IN SURGICAL TREATMENT OF LARGE VESTIBULAR SCHWANNOMAS

Vestibular schwannomas (VS) frequently referred to as acoustic neuromas are the most common tumours of the cerebellopontine angle. They are benign, generally slow-growing tumors that arise from the vestibular portion of the eighth cranial nerve. For patients with large vestibular schwannomas or those exhibiting symptoms from the tumor’s mass effect, surgical intervention remains the preferred treatment approach. This paper discusses the surgical management of patients with large vestibular schwannomas operated in our department and emphasizes the use of intraoperative monitoring for preserving facial nerve function. We review the key surgical steps and highlight the importance of preoperative planning, patient position, and the use of microsurgical techniques to optimize the surgical outcome. Gross total resection of large vestibular schwannomas is associated with worse facial nerve outcomes. Our preferred treatment strategy, especially for older patients, is planned subtotal resection followed by periodic imaging evaluation and radiotherapy in cases of documented tumor growth. This approach may lead to superior facial nerve preservation and improved quality of life for individuals with large vestibular schwannomas. Conclusion The optimal treatment approach for vestibular schwannoma remains a subject of debate. Gross total resection has traditionally been the gold standard for large tumors, but this is often accompanied by a higher risk of postoperative facial nerve dysfunction. Planned subtotal resection with the goal of preserving facial nerve function, followed by closed observation is an alternative approach.

BN SO10 - Virtual Reality in Acute Pain Management of Adult Surgical Patients: Literature Review

Abstract Background Pain is an unavoidable side effect of medical procedures. British Pain Society (BPS) reports almost 10 million people in UK suffer from pain everyday. BPS reported an estimated €5 million per year is spent on managing back pain alone. Pharmaceutical pain management is costly and can cause side effects. Virtual Reality (VR) is a novel technology used to alleviate pain. We performed a literature review to assess the current advances in the pain management using VR. Method A literature search was done on the use of VR for pain management across 4 databases (Pubmed, Medline, Embase and Cinahl) using key words virtual reality, acute pain, adult, surgery. 144 non-duplicated studies were found. 66 studies were excluded: 41 were non-acute pain related, 16 involved chronic pain, 9 involved paediatric population. 78 studies with the total number of 1514 patients (n=1514) were included. All studies used VR to relieve acute pain symptoms experienced while undergoing a procedure. The data included sample size, gender, age, specialty, VR type, pain scale, pain score before and after, interventions, key findings and limitation. Results VR was tested to control pain in general surgery, plastics, obstetrics and gynaecology, cardiothoracics, orthopaedics, urology, and dentistry. In benign UGI surgery, including fundoplication, paraesophageal hernia repair, esophageal myotomy, and pyloroplasty requiring an overnight stay, the use of VR reduced pain, anxiety and nausea. Overall, no adverse outcomes were reported. No difference in nausea and dizziness between VR and control groups was observed. Active software has been shown to be superior to the passive one. Complete immersion with visual and audio stimulation replaced by VR environment is important. The results were similar in different age groups. Conclusion There is a good body of evidence to support the use of VR in pain management in clinical practice. It acts as a good distraction tool. The use of VR was demonstrated to be beneficial in reducing postoperative pain in benign UGI surgery. However, the main areas of application would be in short procedures where it not only delivers better pain management but also increases patient satisfaction and decreases the need for pharmaceutical analgesia, thus bringing down the overall cost.

Surgical Management in Patients With Liver Cirrhosis: A Multidisciplinary Approach

Objective: The objective of this study is to conduct a systematic review on the surgical management of patients with liver cirrhosis, aiming to investigate strategies that can optimize perioperative care and reduce associated complications. Theoretical Framework: This section addresses fundamental concepts related to liver cirrhosis, including severity classification through the Child-Pugh and MELD systems. The review considers clinical and observational studies discussing surgical interventions and multidisciplinary approaches, establishing a solid foundation for understanding the clinical context. Method: The methodology employed comprises a systematic literature review, selecting studies published between 2010 and 2023. The search was conducted across six databases and supplemented by specialized literature, prioritizing surgical interventions and multidisciplinary team approaches. Results and Discussion: The findings reveal significant challenges, such as elevated morbidity and mortality rates, particularly in patients classified as Child-Pugh B and C. Laparoscopic cholecystectomy emerges as the preferred approach, demonstrating lower complication rates when performed in specialized centers. The discussion contextualizes these findings within the theoretical framework, considering the study's limitations. Implications of the Research: The practical implications suggest the necessity for a multidisciplinary team and careful risk assessment, emphasizing the adoption of minimally invasive surgical techniques and stringent control of ascites to enhance clinical outcomes. Originality/Value: This study contributes to the literature by highlighting the complexity of surgical management in cirrhotic patients and the importance of specific strategies. The relevance of this research is underscored by the need for the development of less invasive techniques and a better understanding of the specific complications faced by these patients.

Cardiac Rehabilitation for Fontan Circulation Patients: A Systematic Review, and Meta-Analysis

Background and Objectives: Despite advances in the surgical management of patients with Fontan circulation, their exercise capacity and quality of life remain significantly impaired. Exercise-based cardiac rehabilitation (CR) offers promising improvements in these areas, but the implementation and adherence to these programmes are often inconsistent. This systematic review and meta-analysis aimed to evaluate the safety, efficacy, and optimal exercise modalities for Fontan patients. Materials and Methods: A systematic search of PubMed, Scopus, Web of Science, and Cochrane Library was conducted on 24 August 2023. Studies were screened and assessed for quality using the Cochrane RoB Tool 2 and STROBE checklist. Meta-analysis was performed using a continuous random-effects model to determine the effectiveness of various CR interventions, including aerobic exercise training (AET), resistance training, and inspiratory muscle training (IMT). Results: A total of 26 studies (7 RCTs, 19 cohorts) comprising 22 distinct cohorts were included, with a total sample size of 428 Fontan patients. The interventions ranged from 4 weeks to 24 months and included AET (18 studies), resistance training (11 studies), and IMT (6 studies). The meta-analysis revealed significant improvements in exercise capacity, with a pooled mean difference in peak VO2 of 1.947 (95% CI: 1.491 to 2.402, p < 0.001). Subgroup analyses showed that combined AET and resistance training had the most robust effect, with a mean difference of 2.11 (95% CI: 1.57 to 2.65, p < 0.001). Home-based interventions showed significant benefits, while supervised and hybrid interventions did not show statistically significant differences. Publication bias was identified, particularly in home-based interventions, where smaller studies demonstrated larger effect sizes, as confirmed by Egger’s test (Intercept = 2.417, 95% CI: 1.498 to 3.337, p = 0.001). However, no significant bias was detected in supervised or hybrid interventions, which displayed symmetrical distributions in funnel plots and non-significant Egger’s test results. Conclusions: CR appears to be an effective intervention for improving exercise capacity in Fontan patients, particularly when combining AET with resistance training. Home-based programmes offer promising results, though the potential for publication bias, especially in smaller studies, warrants cautious interpretation of these findings. Further research is needed to refine protocols, explore long-term outcomes, and determine the underlying mechanisms, particularly for patients with more severe clinical presentations. The low incidence of adverse events across the studies reinforces the safety of these interventions.

Current Management of Pediatric Patients with Post-Burn Scars: Case Study

Background. Post-burn scars are common among pediatric patients. Pathological scarring is clear indication for conservative or surgical management of pediatric patients who continue to grow and develop after the resolution of burn injuries. Such lesions can significantly reduce patients' quality of life and, moreover, cause significant functional and aesthetic discomfort. Clinical cases description. The results of observation over two children (2 years 7 months and 12 years) with developing post-burn scars are demonstrated. Successful management method using physiotherapeutic complex (including monopolar radiofrequency treatment combined with ultrasound therapy, photodynamic therapy, and close-focus X-ray therapy) is presented. Conclusion. Modern trends in post-burn scars management are based on timely implementation of effective and safe methods early on rehabilitation stages and tissue restoration after burn injury to prevent pathological scarring and achieve control over its activity.

Study of Complete Surgical Response of Stage III Oral Carcinoma Patients in Comparison to Primary Surgery Versus Neoadjuvant Methotrexate With Surgery.

Objective This study aims to compare the efficacy of neoadjuvant methotrexate therapy followed by surgery versus primary surgical management in patients with stage III oral carcinoma. Methods Thirty patients diagnosed with stage III oral carcinoma were enrolled in this prospective study at a tertiary cancer research center. The patients were divided into two groups: 15 patients received neoadjuvant methotrexate therapy followed by surgery, while 15 underwent primary surgical management. Outcomes were evaluated based on tumor downstaging, surgical margins, postoperative complications, and the requirement for adjuvant radiotherapy. Results Patients in the neoadjuvant methotrexate group demonstrated significant tumor downstaging, allowing for less extensive surgical procedures, with 33.3% (n=5) undergoing wide local excision (WLE) compared to 13.3% (n=2) in the primary surgery group. Negative surgical margins were achieved in 93.33% (n=14) of patients in the neoadjuvant group versus 53.33% (n=8) in the surgical group. Additionally, only 13.3% (n=1) of patients in the neoadjuvant group required postoperative radiotherapy, compared to 53.33% (n=8) in the surgical group. The recurrence rate over a six-month follow-up period was comparable between the two groups. Discussion Neoadjuvant methotrexate therapy resulted in better surgical and oncological outcomes by downstaging the tumor, reducing the extent of surgery, and minimizing the need for postoperative radiotherapy. The findings suggest that methotrexate, as a neoadjuvant agent, is effective in improving patient outcomes with fewer side effects compared to standard cisplatin-based regimens. Conclusion Neoadjuvant methotrexate therapy offers a viable treatment option for stage III oral carcinoma, demonstrating improved oncological and surgical outcomes, including less invasive surgery, higher rates of negative surgical margins, and reduced postoperative radiotherapy requirements. Further research with long-term follow-up is necessary to validate these findings and explore the long-term impact on survival and recurrence rates.

009. Case Report: Cloacal Exstrophy a Rare Case of Abdominal Defect on Pediatrics

Background: Cloacal Exstrophy (CE) is a rare congenital disorder. CE caused by rupture of the cloacal membrane before the urogenital septum is formed, then causes herniation. CE has incidence of 1: 200,000 to 1: 400,000. Embryologically, CE is considered to be the result of a defect in the caudal mesoderm, around 29 developmental days, or failure of mesodermal migration during the primitive streak period resulting in failure of cloacal septation. The aims and objectives of this case report are to explain the case in depth with existing literature and its suitability. Case: The method used is prospective direct observation. The case, a female 2-days-old patient, presented with omphalocele, ileal prolapse, incompletely formed hindgut, open bladder, abdominal wall defect, and urine come from the hemiblader and meconium from the cecal plate. The patient was born via cesarean because the mother with fetal distress. The patient underwent a Dual Stage Pathway (DSP), first the abdominal wall defect was closed with a colostomy, then bladder reconstruction was carried out. The reconstruction procedure in CE cases can be carried out with Dual Stage Pathway (DSP), which consists of omphalocele reconstruction, bladder closure, gastrointestinal diversion and closure of the abdominal wall. Conclusion: CE is a congenital disorder in many organ systems including neurological, gastrointestinal, musculoskeletal, renal and genitourinary. Surgical management of CE patients requires multidisciplinary care with a multi-stage approach.

A Rare Case of Pulmonary Vascular Anomaly: MDCT Pulmonary Angiography in Diagnosis of Arteriovenous Malformation and Post-operative Imaging

Objective. To demonstrate the diagnostic algorithm and tactics of a surgical management of patients with pulmonary arteriovenous malformations.Materials and Methods. Based on a patient`s clinical data analysis, further examination tactic was chosen: in the pre and postoperative periods multispiral computed tomography (MSCT) angiopulmonography (on a Canon Aquillion Prime, Japan) was performed before and after intravenous administration of a iodine-containing contrast agent (Ultravist, 370 mg/ ml) at the rate of 1 ml/kg. Brain magnetic resonance tomography was performed on a Signa Voyager, General Electric, China, 1,5 Tl in the pulse sequences T1, T2, T2 FLAIR, DWI, SWAN in three mutually perpendicular planes with a slice thickness of 1-5 mm to examine the neurological complications. Interventional angiopulmonography was implemented by using General Electric Innova IGS530, France, angiographic system before and after endovascular occluder ("AMPLATZER Vascular PLUG 4", USA) and spirals ("2D-Helical-35" 9 mm in diameter and 2,7 mm long (4 spirals) and "Complex–Helical-18" 11 mm in diameter and 17 mm long, USA) placement. A literature review in Russian and English languages for the last 5 years was searched using CyberLeninka, PubMed Central, Elibrary data bases, by keywords: pulmonary arteriovenous malformation, MSCT angiopulmonography, endovascular treatment. The prospective longitudinal study was conducted in compliance with the principles of ethics in accordance with the Helsinki Declaration, and informed voluntary consent was obtained from the patient.Results. According to clinical and instrumental data, the tactics of combined endovascular treatment of a vascular malformation with subsequent postoperative control was collectively chosen. During the curation, an increase in saturation parameters, general wellbeing improvement, decrease in pulmonary pressure parameters, and diminution in the size of the right heart's parts were achieved.Conclusion. Arteriovenous malformations (AVMs) are rare vascular abnormalities that represent a pathological communication between the arterial and venous bed. The fistulous link leads to an abnormal discharge of blood, bypassing the physiological capillary channel. Radiation and interventional visualization methods play the most important diagnostic, and the latest — therapeutic role in management of patients and are able to establish indications for surgical intervention, prevent the occurrence of life-threating complications: abscesses, paradoxical embolism and heart attacks, progressive respiratory and heart failure.

Transcatheter aortic valve replacement failure: surgical valve explantation after more than a decade.

Transcatheter aortic valve replacement (TAVR) has become an established alternative to surgical aortic valve replacement for severe aortic stenosis. However, the long-term outcomes and need for surgical reintervention following TAVR remain uncertain. This case report describes a 76-year-old woman who underwent surgical explantation of a SAPIEN-XT valve more than a decade after initial TAVR implantation due to late valve failure. The patient presented with severe aortic insufficiency and heart failure symptoms. Surgical intervention involved concomitant ascending aortic replacement, tricuspid annuloplasty, and coronary artery bypass grafting. The TAVR valve was successfully explanted using careful blunt dissection to avoid annulus damage. Postoperative recovery was uneventful, with the patient discharged after 4 weeks. This case highlights the potential need for long-term surgical management of patients after TAVR, and emphasizes the importance of surgical preparedness as TAVR indications expand. It also provides valuable insights for surgeons encountering similar cases of late TAVR failure requiring explantation.

Surgical Options for Retained Gallstones After Cholecystectomy.

Retained gallstones are the most common cause of postcholecystectomy pain. They may be in a long remnant cystic duct (CD), the common bile duct (CBD), or within a remnant gallbladder (GB) post subtotal cholecystectomy. Although endoscopic management is often attempted, occasionally surgical clearance is required. Rates of preoperative surgery to remove stones in a remnant GB are rising due to the increased practice of subtotal cholecystectomy during a problematic laparoscopic cholecystectomy. This study aims to review the surgical management of symptomatic retained stones at a tertiary hepatobiliary referral center in Sydney, Australia. This retrospective analysis of prospectively collected data was performed on patients who underwent an operation for retained stones after a previous cholecystectomy over 18 years (2004-2022). All of the patients with residual CBD stones had failed endoscopic retrograde cholangiopancreatogram (ERCP) attempts or could not have an ERCP because of prior foregut surgery. All patients underwent a systematic preoperative workup confirming the biliary anatomy and pathology. Fourteen patients had surgical intervention for retained stones. All cases were attempted laparoscopically and were successful in 11/14 patients (78%). Retained stones were found within a remnant GB (29%, n=4), a remnant CD (36%, n=5), or the CBD (36%, n=5). Conversion to an open procedure in 3 patients was for dense fibrosis associated with a long low-insertion of the CD, necessitating a hepatico-jejunostomy, failure to delineate the biliary anatomy, and inability to clear CBD stones, respectively. One patient developed a minor postoperative complication (superficial wound infection), and all patients were free of symptoms at a median follow-up of 33.5 months. This study demonstrates favorable outcomes in patients undergoing laparoscopic intervention for retained gallstones. A systematic approach to the workup and surgical management of patients with retained stones is essential.

Knowledge, attitude and practice regarding thirst management in surgical patients among intensive care unit nurses: A cross-sectional study.

The prevalence of thirst in intensive care unit (ICU) surgical patients is high, and its impact is significantly harmful. Nurses play a crucial role in managing thirst. It is essential to develop targeted training programmes for nurses, focusing on their knowledge, attitude and practice (KAP). To investigate KAP regarding thirst management in surgical patients among ICU nurses and the potential influencing factors related to demographic characteristics. This is a cross-sectional study. From August to September 2023, a self-developed questionnaire was distributed online in the ICUs of 14 tertiary general hospitals in Shanghai, China. This questionnaire aimed to assess the KAP of ICU nurses concerning thirst management. Influencing factors were analysed using ANOVA and the rank-sum test. Spearman correlation analysis and stratified regression analysis were employed to evaluate the relationship among KAP. The study was reported according to the STROBE checklist. A total of 530 valid questionnaires were obtained online with a response rate of 86.60%. While ICU nurses generally held a positive attitude towards thirst management, there was a noticeable deficiency in knowledge and a lack of standardization in practice. Nurses with higher educational levels, lower academic titles, who had received training and who were familiar with the consensus and guidelines on thirst management had better attitude towards managing thirst. Younger nurses, those with less ICU working experience, lower academic titles, who had received training and who were acquainted with the guidelines showed better practice. It was observed that knowledge and attitude both had a significant positive influence on practice. KAP regarding thirst management of surgical patients among ICU nurses are interconnected and require enhancement. Targeted training, focused on the identified weakness and influencing factors, needs to be carried out. An innovative and stratified training system can improve the quality of practice, as well as contributing to the professional development of ICU nurses. Further, the findings of the study provide a foundational understanding of thirst management, promoting the advancement of related scientific research.

Comparative outcomes of surgical and conservative management in carotid artery dissection.

Carotid artery dissection (CAD) is a significant cause of strokes in young individuals, leading to severe complications and socioeconomic burdens. Despite antithrombotic therapy being the primary management strategy, optimal treatment for patients with recurrent or worsening symptoms remains undefined. This study aims to describe the characteristics and evaluate the outcomes of conservative versus surgical management in CAD patients. A total of 23 patients presenting with CAD from November 2014 to December 2021 were reviewed retrospectively. Patient demographics, vascular risk factors, symptoms, imaging results, treatment details, and follow-up information were collected and analyzed. Propensity score matching (PSM) was utilized to enhance comparability. The mean age of the patients was 46.4 ± 9.4 years, with a median follow-up of 12 (range 3-90) months. Of the 23 patients reviewed, seven underwent endovascular treatment or open surgery due to unresponsiveness to conservative therapy, while 16 received conservative management. All patients showed regression of symptoms. Surgical patients showed a significant improvement with a 100% patency rate during the follow-up. PS matching adjusted for baseline differences, yielding comparable groups for analysis. No significant difference between treatment approaches was observed in stroke recurrence rates, although surgical intervention showed promising outcomes in symptom resolution and stroke prevention. Both conservative and surgical management of CAD can lead to favorable outcomes. While conservative therapy remains the initial approach and proves effective, surgery appears beneficial and safe in certain cases unresponsive to conservative treatment. Further investigation through larger prospective and randomized trials is necessary to establish its safety and efficacy.

National centralization of Hirschsprung’s disease in Sweden: a comparison of postoperative outcome

BackgroundIn Sweden, surgical treatment of Hirschsprung’s disease (HSCR) was centralized from four to two pediatric surgery centers 1st of July 2018. In adults, centralization of surgical care for complex or rare diseases seems to improve quality of care. There is little evidence supporting centralization of pediatric surgical care. The aim of this study was to assess surgical management and postoperative outcome in HSCR patients following centralization of care.MethodsThis study retrospectively analyzed data of patients with HSCR that had undergone pull-through at a pediatric surgery center in Sweden from 1st of July 2013 to 30th of June 2023. Patients managed from 1st of July 2013 to 30th of June 2018 (before centralization) were compared with patients managed from 1st of July 2018 to 30th of June 2023 (after centralization) regarding surgical treatment, unplanned procedures under general anesthesia or readmissions up to 90 days after pull-through as well as complications classified according to Clavien–Madadi up to 30 days after pull-through.ResultsIn the 5-year period prior to centralization, 114 individuals from 4 treating centers were included and compared to 83 patients from 2 treating centers in the second period. There was no difference regarding age at pull-through or proportion of patients with a stoma prior to pull-through. An increase of laparoscopically assisted endorectal pull-through (8.8% to 39.8%) was observed (p < 0.001). No significant differences were seen in postoperative hospital stay, unplanned procedures under general anesthesia, or readmissions up to 90 days after pull-through. There was no difference in severe complications (Clavien–Madadi ≥ 3); however, HAEC treated with antibiotics increased following centralization (10.5–24.1%; p = 0.018).ConclusionCentralization of care for HSCR does not seem to delay time to pull-through nor reduce severe complications, unplanned procedures under general anesthesia or readmissions up to 90 days after pull-through. The increased HAEC rate may be due to increased awareness of mild HAEC.Level of evidence: Level III.

Surgical Management of Pediatric Patients with Intraocular Tumors

The incidence and prevalance of intraocular tumors in pediatric and adult populations are different. Moreover, the same type of tumor may show different clinicopathologic features in the pediatric group. Several types of treatment strategies have been described for benign and malign intraocular tumors: observation, cryotherapy, thermotherapy, laser photocoagulation, surgical excision, plaque brachytherapy, radiotherapy, chemotherapy, and enucleation. The purpose of treatment is to control tumor, preserve or prolonge patients life and to preserve eyeball and vision. Surgical excision or resection can be performed as a primary treatment or adjuvant or salvage procedure. Nowadays, surgical treatments like sclerouvectomy and/or vitrectomy is applied increasingly in pediatric population with intraocular tumor.

Tackling the tubes of refractory Sturge–Weber syndrome with secondary glaucoma: A surgeon’s nightmare!

Hypotony with shallow anterior chamber (AC) post glaucoma surgery in Sturge–Weber syndrome (SWS) patients is commonly due to choroidal effusions. We report two cases of SWS patients having hypotony and shallow AC after Ahmed Glaucoma valve (AGV) implantation with no wound leak or choroidal effusion. Case 1 had persistent shallow AC, which was diagnosis of exclusion, as valve malfunction, a rare occurrence in AGV. Case 2 resolved after AC reformation with 1.8% sodium hyaluronate. Two cases describe the clinical approach and surgical management in patients of hypotony with shallow AC after AGV implantation in SWS patients.

Gender differences in spine surgery for degenerative lumbar disease: prospective cohort study.

Despite efforts toward achieving gender-based equality in clinical trial enrollment, females are frequently underrepresented and gender-specific data analysis is lacking. Identifying and addressing gender bias in medical decision-making and outcome reporting may facilitate more equitable healthcare delivery. This study aimed to determine if gender differences exist in the clinical evaluation and surgical management of patients with degenerative lumbar conditions. Consecutive adult patients undergoing spinal surgery for degenerative lumbar conditions (disc herniation [DH], spinal canal stenosis [SCS], and degenerative spondylolisthesis [DS]) were prospectively enrolled across 16 tertiary academic centers. Outcome domains included pain, disability, health-related quality of life (HRQOL), expectations of surgery, and satisfaction with surgical outcome. Covariates pertaining to the preoperative use of healthcare resources, diagnostic testing, and visits to healthcare providers were compared between genders before and after propensity score matching for 13 baseline demographic and procedural variables. Data were analyzed for 5038 patients (2396 female, 2642 male) with degenerative spinal pathologies including SCS (40.2%), DS (33.2%), and DH (26.6%). Surgical treatment effect was similar for both genders. For all conditions, female patients had worse pre- and postoperative pain, disability, and HRQOL. Significant gender differences were identified for marital status, education, employment status, exercise activities, and disability claims. Female patients were more likely to use select medications, diagnostic imaging tests, and nonsurgical therapeutic interventions, and access various healthcare providers. Findings were similar following post hoc propensity score matching. In this multicenter, prospective, observational cohort study, male and female patients benefitted similarly from surgery for degenerative lumbar spine disease. However, female patients had worse preoperative clinical assessment scores and were more likely to use select healthcare resources.

S1499 Trends in Medical and Surgical Management of Patients With Inflammatory Bowel Disease and Concomitant Human Immunodeficiency Virus Infection in the United States: A Population-Based Study

S1499 Trends in Medical and Surgical Management of Patients With Inflammatory Bowel Disease and Concomitant Human Immunodeficiency Virus Infection in the United States: A Population-Based Study

Practice Advisory for Postoperative Pain Management of Cardiac Surgical Patients: Executive Summary: A Report by Society of Cardiovascular Anesthesiologists

Practice Advisory for Postoperative Pain Management of Cardiac Surgical Patients: Executive Summary: A Report by Society of Cardiovascular Anesthesiologists

Machine Learning for Treatment Management Prediction in Laryngeal Fractures

ObjectivesLaryngeal fractures are rare but potentially life-threatening traumas. Complications, such as airway obstruction and disrupted laryngeal anatomy, associate with significant morbidity. Early identification of at-risk patients and optimal management remain crucial for improved outcomes. Recently, machine learning (ML) has attained great attention as a unique and novel technique for evaluating complex non-linear relationships between multiple observations to create a predictive model with greater accuracy. This study aimed to demonstrate the potential of ML in predicting airway and surgical management of laryngeal fracture patients and identify key contributing parameters for the predictive performance of the ML models. MethodsThe ML models were developed using a patient series managed at the Helsinki University Hospital during 2005–2019. The developed models were further evaluated independently using a different cohort collected from the same institution between 1995–2004. ResultsThe ML showed a weighted area under curve (AUC) of 0.93 and accuracy of 0.86 following training for airway management. Likewise, for treatment approach, weighted AUC was 0.85 and accuracy 0.78. Injury type, Schaefer-Fuhrman grade (SF gr), age at incident, cause of injury, and fracture of the cricoid, in decreasing order of significance, were the most prominent features for the model's predictive performance for airway management. Similarly, our model identified SF gr, fracture of the cricoid, injury type, age at incident, and cause of injury as the most significant predictors for surgical treatment approach. ConclusionsThe proposed prediction of management approach by an ML technique can provide accurate predictions and thus aid clinicians in administering early and personalized interventions. The model may serve as a supporting tool in recognizing at-risk patients and in timely decision making. Further independent external validation is warranted for model generalizability.