Abstract The study attempted to assess the water quality around the tannery effluent discharge areas for suitability for irrigation purposes using different indices (Water Quality Index (WQI)) and statistical analysis in Savar Upazilas, Dhaka, Bangladesh. The samples were collected three times, from monsoon 2021 to pre-monsoon 2023. The analysis results showed that the concentrations of various parameters at most of the sampling points exceeded the surface water standard. Pollution levels were found in the following order: pre-monsoon, post-monsoon, and monsoon. At SW1 point, the CWQI, WWQI, and MWQI of the surface water quality showed a ‘poor’ category. The IWQI values showed that the surface water at all the sampling points was suitable for irrigation purposes, except for the SW1 sampling point. The NPI indicates that EC, BOD, COD, TSS, Cl−, Na+, and NO3--N parameters were potentially responsible for polluting most sampling sites. Multivariate statistical analyses like principal component analysis, cluster analysis, and Pearson correlation matrix showed significant anthropogenic intrusions of these variables in surface water in the area. A strong correlation between these parameters indicated their common origin, i.e., poorly treated tannery industry effluent entered the surface water, suggesting an improvement in the efficiency of the Central Effluent Treatment Plant (CETP).