This paper presents a series of numerical and field studies to examine the accuracy of two field-scale Parshall flumes, which are employed to measure the flow rate of a wastewater system in the city of Minneapolis, Minnesota. The numerical studies were carried out using the large-eddy simulation (LES) and level-set methods to compute the turbulent flow of sewers under two-phase flow (wastewater and air) conditions. Flow rate measurements in the field were conducted using the dye dilution approach and an in-site flow measuring tool. Using the combination of field measurements and numerical simulations, this research aims at quantifying (i) the margin of error of the filed-scale Parshall flumes and (ii) the water surface fluctuations within the Parshall flumes. The LES turbulent model, coupled with the level-set method, allowed for resolution of instantaneous water surface variations and uncertainty quantification of the flow rate measurements.