The fluorescent molecule dihematoporphyrin ether (DHE), which is known to become sequestered in cells and which is currently being used for “photoradiation” cancer therapy in clinical trials, may organize into two-dimensional arrays at a water-membrane interface. Some of the consequences of such ordering could be as follows: (1) to create a light-gathering apparatus in the cell analogous to chlorophyll in photosynthetic units; (2) to participate in the cytotoxicity mechanism of DHE, leading to the detection of anisotropy in the absorption and/or emission of visible light which would allow coupling of (cytotoxic) optical energy to the cell membrane; (3) to enhance the DHE—singlet-oxygen cytotoxicity mechanism considered to be operative in cancer cells. We present here evidence for the existence of these arrays, based on evaluation of surface pressure vs. trough area data, polarized and unpolarized visible reflectance spectra on water, and polarized and unpolarized UV-visible spectra on glass. Preliminary conclusions are as follows. 1. (1) DHE forms a film at water-air and water-fatty-acid-air interfaces and probably lies with its ring planes parallel to the water in an “overlapped” configuration. 2. (2) A shift from one absorbing species of DHE to another may occur at the water-air interface during compression experiments. 3. (3) DHE orientation at an interface may be affected by fatty acid present at the interface. 4. (4) A preferential orientation of DHE oscillators probably exists on a solid support. We investigate the analogy between DHE and the light-gathering chlorophyll photosynthetic unit, and the anisotropic (directional) capabilities of ordered DHE in Langmuir-Blodgett films and cells.