Lung aerosol ventilation studies may be accompanied by airborne contamination, with subsequent surface contamination. Airborne contamination has been measured prior to, during and following 59 consecutive 99Tcm-diethylenetriamine pentaacetate (DTPA) aerosol studies using a personal air sampler. Airborne contamination ranging between 0 and 20 330 kBq m-3 has been measured. Airborne contamination increases with degree of patient breathing difficulty. The effective dose equivalent (EDE) to staff from ingested activity has been calculated to be 0.3 microSv per study. This figure is supported by data from gamma camera images of a contaminated staff member. However, surface contamination measurements reveal that 60% of studies exceed maximum permissible contamination limits for the hands; 16% of studies exceed limits for controlled area surfaces. The EDE from ingestion is low, but protective clothing is essential to prevent body and clothing contamination. Ingested activity and surface contamination results from this study have been compared with results from a Technegas study.