The reintroduction of surface arthroplasty of the hip with metal-on-metal bearings has the potential to eliminate or substantially reduce long-term wear-induced osteolysis as the major cause of failure. To determine important modes of failure, implant retrieval analysis was done on 98 failed surface arthroplasty components from different manufacturers. Analysis involved sectioning the components, measuring cement mantle thickness and the depth of penetration, histopathology, and measurement of the bearing wear. A finite element model was constructed to examine cement thermal necrosis. Femoral neck fracture and femoral loosening were the main causes of failure. The finite element model showed thermal necrosis could occur when cysts were filled with cement. Histologic observations verified necrosis of interfacial bone, although adaptive remodeling was commonly seen. The amount of cement varied considerably with implant type, and failure mode and was greater in loosened components. Although implant failure is multifactorial, these observations should be a cause for concern in current cementing techniques in which controlling mantle thickness and extent of penetration may be difficult. Optimizing cement technique to avoid leaving the component proud, and to avoid extensive cementation of the femoral head, may be important in reducing some modes of failure. With the application of metal-on-metal bearings, surface arthroplasty is again being performed in a growing number of centers worldwide. Although relatively few procedures have been performed in the United States, thousands of surface arthroplasty components have been implanted in Europe and Australia. We anticipate the problems faced by the first generation of metalpolyethylene surface arthroplasties, primarily related to debris-induced osteolysis caused by polyethylene wear, can be overcome by the current generation of low wearing metal-on-metal surface arthroplasties. Short-term clinical followup reports of metal-on-metal surface arthroplasties have been encouraging, although femoral neck fractures and femoral loosening have been identified as causes of failure. Risk factors in surface arthroplasty highlight the importance of patient selection criteria and good bone quality for implant survival. Currently, the role of femoral head vascularity in implant durability is controversial; some surgeons are concerned the posterior surgical approach sacrifices the important extraosseous blood supply to the femoral head, whereas others believe adequate blood supply will be provided intraosseously. Although the reduced wear of metal-on-metal bearings is well recognized, there have been concerns that heat-treating the components after casting can lead to higher wear, possibly sufficient to cause osteolysis. The unknown long-term consequences of metal wear debris are also a concern. Despite these concerns, the conservative nature of surface arthroplasty and the restoration of a high degree of function, including the ability to return to sports, make this surgery appealing From the Joint Replacement Institute at Orthopaedic Hospital, Los Angeles, CA; UCLA David Geffen School of Medicine, Los Angeles, CA; J. Vernon Luck Research Center at Orthopaedic Hospital, Los Angeles, CA; Division of Orthopedic Surgery/Chirurgie Orthopedique, University of Ottawa, Canada; and ANCA Clinic, Heusden, Belgium. The institution of one or more of the authors (PC, PEB, KDS, HCA) has received funding from Wright Medical Technology; PEB, KDS, HCA are consultants for Wright Medical Technology. One or more of the authors has received funding from the William G. McGowan Charitable Fund (PC, PEB, MLD, HCA), the Orthopaedic Hospital Foundation (PC, PEB, MLD, EE, ZL, HCA) and Wright Medical Technology, USA (PC, PEB, KDS, HCA). Each author certifies that his or her institution has approved the human protocol for this investigation and that all investigations were conducted in conformity with ethical principles of research, and that informed consent for participation in the study was obtained. Correspondence to: Pat Campbell, PhD, Orthopaedic Hospital, 2400 S. Flower Street, Los Angeles, CA 90007. Phone: 213-742-1134; Fax: 213744-1175; E-mail: pcampbell@laoh.ucla.edu. DOI: 10.1097/01.blo.0000238777.34939.82 CLINICAL ORTHOPAEDICS AND RELATED RESEARCH Number 000, pp. 000–000 © 2006 Lippincott Williams & Wilkins
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