Those of us who coordinated this monograph, and singed this presentation, sought to address some issues we considered relevant regarding the alignment between Supranational Education and Higher Education. We wanted to match some hypothesis we initially had and that we tried to synthesize in the title of this article. We have been able to find evidences related to an increasingly stronger direct impact between the education policy of international organizations – analyzed from the Supranational Education – and the higher education institutions. That impact is increasingly broader from a threefold perspective: from the geographic perspective – with large regions of the planet, in a globalization context, affected by supranational trends -; from an intensity perspective – as the effect is increasingly inevitable by the higher education institutions-; and from a tematic perspective – as it increasingly covers a greater number of topics.We also confirmed that these impacts have had a broad effect on social change. The assumption of new mercantilist paradigms of the new approaches to quality, the social mission of higher education, or gender issues directly affect citizens’ lives. And they do so from global perspectives. Thus, we verify what we suggested in the title of this modest contribution to the monograph, that the Supranational Education and the Higher Education can be keys to global transformation for the complex societies in which we currently live: as frameworks to understand the changes and as levers to promote them.