The objective of this work is to develop low Pt loading oxygen reduction catalysts with high activity and good stability, which are essential for DOE's mission for next generation fuel cells. Two strategies are pursued: (1) The first approach involves the creation of hybrid cathode catalysts (HCC) that are a combination of N- containing carbon composite catalysts (CCC) developed at USC with platinum for oxygen reduction. Besides its own contribution to the overall catalyst activity (an advantage over conventional carbon black supports), the CCC can enhance the activity of the Pt through synergistic effects. (2) The second strategy involves the use of corrosion-resistant TiO 2 as a catalyst support for Pt to eliminate high degradation rate of the standard carbon support. The TiO 2 with high surface area is developed at USC, which is superior to carbon support in terms of stability at high potentials. Our preliminary experimental results demonstrate that the proposed strategies are very promising in scientific and engineering aspects for developing low Pt loading cathode catalysts.