High voltage electric field power supply with a wide output voltage range is widely used in microwave generating, X-ray, ion implantation, and other fields. However, the existing high voltage power supplies cannot meet the demand of wide voltage regulation range for high-voltage high-power magnetrons. In this paper, a multi-mode high voltage DC-DC converter with a wide output voltage range is proposed, which is composed of two input series connected full-bridge inverters, six inductor – inductor – capacitor (LLC) resonant networks, and two types of voltage multipliers. The proposed high voltage power supply owns six operation modes and five available output voltage ranges by modifying the inverter's driving scheme. Thus, the proposed converter can reduce the variation range of the resonant network's gain when regulating the output voltage widely. In this paper, a detailed comparative analysis is presented of the operating principle of the proposed topology and its six operation modes. Moreover, the expression of its output voltage gain is shown with the control strategy. Finally, a 7.5kW 3.5-10kV output prototype is built to verify. The results convincingly demonstrate the applicability of the proposed converter offering high efficiency over a wide range of output power.