Superficial Damage Research Articles

TO THE LEARNING ABOUT SELF-INFECTION OF THE MOTHERS IN LABOR

Various kinds of diseases, known under the common name of childbirth fever, are caused by the penetration of pathogenic microbes into the genitals during childbirth, the postpartum period, and even sometimes during pregnancy. The main place of introduction of microbes is the inner wounded surface of the uterus, and then all sorts of superficial and deep damage to the genital canal, due to the most generic act. In view of this, according to the existing view, especially in Germany, the diseases that now occupy us are the essence of infectious diseases of wounds emanating from the genital area. According to the influence of microbes, the course and partly the influence of therapeutic measures, postpartum diseases are divided into: 1) septic diseases in the broad sense of the word, caused by the introduction of pathogenic microbes into living tissue and 2) putrefactive poisoning, which occurs from the blood metabolism of micronutrients in the beginning - Saprmia (Duncan), There are pure cases of both forms; but much more often it is difficult to separate one form from another. The method of infection that complicates ordinary wounds is not thought at all, being content only with the definition of it, in full conviction that it, as it were not transmitted to the wound, always occurs from the outside. In obstetrics, in relation to the way of infection, the case seems to be more complicated and confusing; as there is a special type of infection known as "self-infection"

Methods for Endoscopic Removal of Over-the-Scope Clip: A Systematic Review.

Aims The over-the-scope clip (OTSC) has recently emerged as a new endoscopic device for treating gastrointestinal bleeding, perforations, fistulas, and leaks. A modified OTSC device (full-thickness resection device, FTRD) has been widely used for endoscopic full-thickness resection. However, there is less experience regarding the indications and methods for OTSC removal. We aimed to summarize the existing methods and indications for OTSC removal. Methods We searched PubMed, Cochrane Library, and ClinicalTrials.gov to identify relevant publications on OTSC removal. The details of OTSC removal, including the methods, indications, success rates, adverse events, and failure causes, were extracted and summarized. A meta-analysis of pooled success rates was conducted using STATA 15.0. Results Eighteen articles were included. The reported methods for OTSC removal included (1) grasping forceps, (2) the Nd : YAG laser, (3) argon plasma coagulation, (4) the remOVE system, (5) endoscopic mucosal resection/endoscopic submucosal dissection, and (6) ice-cold saline solution. Indications for OTSC removal were (1) poor healing, (2) OTSC misplacement, (3) repeat biopsy/therapy or further treatment, (4) adverse events after OTSC implantation, (5) removal after recovery, and (6) patient wishes. The pooled success rate of OTSC removal was 89% in patients treated with the remOVE system. Minor bleeding, superficial thermal damage, and superficial mucosal tears were common adverse events. Mucosal overgrowth was the main cause of OTSC removal failure. Conclusions The remOVE system is the best investigated method, with sufficient efficacy and safety for OTSC removal. This is the first systematic review of OTSC removal and provides significant guidance for clinical practice.

A Novel Infrared Thermography Sensing Approach for Rapid, Quantitative Assessment of Damage in Aircraft Composites.

The current necessity of the scientific and industrial community, for reduction of aircraft maintenance cost and duration, prioritizes the need for development of innovative nondestructive techniques enabling fast and reliable defect detection on aircraft fuselage and wing skin parts. Herein, a new low-cost thermographic strategy, termed Pulsed Phase-Informed Lock-in Thermography, operating on the synergy of two independent, active infrared thermography techniques, is reported for the fast and quantitative assessment of superficial and subsurface damage in aircraft-grade composite materials. The two-step approach relies on the fast, initial qualitative assessment, by Pulsed Phase Thermography, of defect location and the identification of the optimal material-intrinsic frequency, over which lock-in thermography is subsequently applied for the quantification of the damage’s dilatational characteristics. A state-of-the-art ultra-compact infrared thermography module envisioned to form part of a fully-automated autonomous nondestructive testing inspection solution for aircraft was conceived, developed, and tested on aircraft-grade composite specimens with impact damages induced at variable energy levels and on a full-scale aircraft fuselage skin composite panel. The latter task was performed in semi-automated mode with the infrared thermography module mounted on the prototype autonomous vortex robot platform. The timescale requirement for a full assessment of damage(s) within the sensor’s field of view is of the order of 60 s which, in combination with the high precision of the methodology, unfolds unprecedented potential towards the reduction in duration and costs of tactical aircraft maintenance, optimization of efficiency and minimization of accidents.

Foot injury survival in red abalone (Haliotis rufescens)

Recovery of the U. S. Federal Endangered Species Act-listed white abalone (Haliotis sorenseni) in California, USA depends on the success of a captive breeding program, which requires collection of wild broodstock to maintain genetic diversity. Foot damage is frequently sustained during collection and handling, and severe injuries can be fatal. This study used the proxy species red abalone (Haliotis rufescens) to investigate the ability of abalone to survive foot injury by administering foot injuries varying in severity and monitoring subsequent health and survival. In a preliminary study, 6/6 farm-origin 55–70 mm animals survived two types of injury while 5/6 survived a third type of injury. We then conducted a definitive study using 24 wild-origin animals (165–207 mm) and three intensified injury treatments. Five of six animals that received a deep tissue incision were dead the following morning, presumably from acute hemolymph loss, and the remaining animal in that treatment group died on day 41 with a systemic bacterial infection. Nine of twelve abalone that received loss of either 8% or 17% of foot sole epithelium survived until experiment termination at day 90, at which time all survivors were regenerating epithelial tissues, as evident by histology. This study suggests that abalone may be more capable of surviving significant superficial foot damage that can occur during collection and handling, at least in a captive rearing environment, than has been previously recognized.

Dexpanthenol in Wound Healing after Medical and Cosmetic Interventions (Postprocedure Wound Healing).

With the availability of new technologies, the number of subjects undergoing medical and cosmetic interventions is increasing. Many procedures (e.g., ablative fractional laser treatment) resulting in superficial/minor wounds require appropriate aftercare to prevent complications in wound healing and poor cosmetic outcome. We review the published evidence of the usefulness of topical dexpanthenol in postprocedure wound healing and the associated mechanisms of action at the molecular level. A search in the PubMed and Embase databases was performed to query the terms dexpanthenol, panthenol, superficial wound, minor wound, wound healing, skin repair, and postprocedure. Search results were categorized as clinical trials and in vitro studies. In vitro and clinical studies provided evidence that topically applied dexpanthenol promotes superficial and postprocedure wound healing. Latest findings confirmed that dexpanthenol upregulates genes that are critical for the healing process. The gene expression data are of clinical relevance as evidenced by prospective clinical studies indicating that topical dexpanthenol accelerates wound healing with rapid re-epithelialization and restoration of skin barrier function following skin injury. It can therefore be inferred that topical dexpanthenol represents an appropriate and state-of-the-art treatment option for superficial postprocedure wounds, especially when applied early after the superficial skin damage.

Macular Perfusion Changes and Ganglion Cell Complex Loss in Patients with Silicone Oil-related Visual Loss

ObjectiveThe aim of this study was to investigate macular perfusion changes and ganglion cell complex (GCC) loss in patients with unexplained visual loss following vitrectomy and silicone oil (SO) tamponade, and to evaluate the correlation between retinal blood flow and GCC loss using optical coherence tomography angiography (OCTA) and optical coherence tomography (OCT). MethodsThis retrospective study included seven eyes (seven patients) with unexpected visual loss after vitrectomy and SO tamponade. OCTA was used to evaluate the alterations in retinal vessel density (VD) in the superficial capillary plexus (SCP), deep capillary plexus (DCP), and radial peripapillary capillary plexus (RPCP). OCT was used to measure the thickness of GCC and retinal nerve fiber layer (RNFL). Medical records of patients were reviewed. ResultsQuantitative analysis of OCTA images revealed a significant reduction in SCP VD in the affected eyes compared with the controls (all sections P < 0.05). No difference was found in GCC thickness, but FLV (focal loss volume) and GLV (global loss volume) were significantly higher in the affected eyes (both P < 0.001). SCP VD was inversely correlated with FLV and GLV. ConclusionsSilicone oil-related severe visual loss was associated with superficial retinal microvasculature damage and ganglion cell apoptosis.

Arthroscopically Assisted Tape Augmentation for Anterior Talofibular Ligament Repair

In this Technical Note, we describe arthroscopically assisted tape augmentation of a modified Broström repair for chronic lateral ankle instability. Specifically, this technique involves talar anchor placement under direct arthroscopic visualization combined with a minimally invasive approach for anatomic anterior talofibular ligament repair and FiberTape (Arthrex, Naples, FL) augmentation. The primary advantage of our technique compared with open InternalBrace (Arthrex) techniques is that only a 2-cm incision is made and no subcutaneous suture passing and knot tying are required, which bear the danger of superficial peroneal nerve damage. In addition, the risk of nonanatomic anchor placement is diminished owing to direct arthroscopic visualization and preparation of the anterior talofibular ligament remnants.

Corneal damage and its recovery after instillation of preservative-free versus preserved latanoprost eye drops

Purpose: Latanoprost ophthalmic solution is highly effective as a therapeutic agent for glaucoma and is applied worldwide. However, harmful effects on the corneal surface have been reported regarding the commercially available latanoprost ophthalmic solution. Corneal surface toxicity may be caused by the added preservative of the ophthalmic solution. In order to ascertain whether latanoprost itself can damage the cornea or if this is solely due to the added preservatives, this study attempted to determine the corneal changes that occur at different time periods following usage of preservative-free versus preserved latanoprost eye drops.Materials and methods: Preservative-free latanoprost eye drops (Monoprost®) or preserved latanoprost eye drops (Xalatan®) containing 0.02% benzalkonium chloride (BAC) were instilled in the corneas of rabbits. For each of the two different eye drop solutions, the rabbits used in this experiment were divided into three exposure groups: 1 minute, 24 hour, and 1 week groups. Corneal transepithelial electrical resistance (TER) and scanning electron microscopy (SEM) were examined immediately (1 minute) after instillation, at 24 hours after instillation, and at 24 hours after 1 week of daily instillations of latanoprost. Hank’s balanced salt solution was used in the control group.Results: The mean corneal TER of the control group was 933.8 ± 279.0 Ω cm2. In preservative-free latanoprost instilled corneas, there was no significant decrease in the TER or morphological changes at any of the time points, with the relative TER values of 117 ± 38%, 100 ± 34%, and 93 ± 21% for 1 minute, 1 day, and 1 week time points, respectively. In preserved latanoprost instilled corneas, SEM showed that only the immediate group exhibited superficial cell damage and a significant decrease in the corneal TER compared to the controls and other time points and to the immediate preservative-free latanoprost corneas. In the preserved latanoprost groups, the relative TER values were 18 ± 5%, 110 ± 28%, and 92 ± 10%, for the three respective observation time points.Conclusions: Preservative-free latanoprost can be safely instilled to the corneal epithelium. Latanoprost with 0.02% BAC has an immediate deleterious impact on the corneal epithelium; however, it disappears within 24 hours after instillation.

Influence of temperature dependent matrix properties on the high-rate impact performance of thin glass fiber reinforced composites

The influence of measurement temperature on the high velocity (>100 m/s) impact performance was investigated for three thermosetting epoxy resin S-2 glass composite systems. These three model resins were chemically similar but have different glass transition temperatures (Tg) and molecular weights between crosslinks (Mc) through the use of different diamine curing agents (Jeffamine® D230, D400, and D2000). Impact performance was quantified by the projectile kinetic energy absorbed (KE50) as calculated from the characteristic ballistic velocity (V50) of the composites during high velocity impact. Among the resin systems, the KE50 remained essentially constant over a broad range of temperatures for each composite set and modestly increased with decreasing Mc. The superficial damage area associated with delamination showed remarkable sigmoidal behavior as a function of the testing temperature relative to the Tg (T-Tg). Damage was high for low T-Tg values (glassy resin) and decreased as the resin traversed its Tg into the rubbery region. These damage area trends were found to depend on the resin Mc, with higher Mc values resulting in lower overall damage area and a lower inflection point temperature. High speed videography of the back surface of the samples showed that lower damage areas correlated with an increased back face deflection, which enabled energy absorption with relatively less delamination. Composite mechanical tests were performed to validate the impact performance and explain the deformation mechanisms observed during impact energy dissipation. Our results illustrate the critical importance of the resin architecture and temperature-dependent viscoelastic behavior on the impact properties of composites for impact-resistance applications.

Novel anterior curved incision combined with MIPO for Pilon fracture treatment

BackgroundsPoor prognosis was reported for complex Pilon fractures involving severe soft tissue damage. It is therefore useful to explore the evolution of different treatment strategies in an effort to reconstruct the axial alignment and articular surface, while minimizing additional damage to the surrounding soft tissues.MethodsSeventeen patients with Pilon fractures were enrolled in this retrospective study from December 2009 to October 2014. The injuries were graded according to AO Classification and the Gustilo-Anderson system. Patients were treated with minimally invasive plate osteosynthesis (MIPO) combined with curved incision on the anterior area of ankle. The ankle function and radiological outcome were assessed by the modified Mazur ankle score and Burwell-Charnley criteria, respectively. Visual analogue score (VAS) score was used to assess the degree of patient’s ankle pain, and related complications were also recorded.ResultsThe mean time for fracture healing was 3.6 months (range: 3–6 months). According to Mazur’s criteria, surgical treatment achieved good or excellent outcome in 15 (88.2%) cases, and the average VAS score was 1.19 ± 0.52. On the basis of Burwell-Charnley score, 12 (70.5%) patients achieved anatomic recovery, 4 (23.5%) obtained good reduction, and only 1 (5.9%) patient was diagnosed with valgus deformity. Additionally, 1 (5.9%) patient developed a superficial infection around incision, and 2 (11.8%) experienced superficial peroneal nerve damage. In addition, 2 (11.8%) patients showed radiographic evidence of existing ankle osteoarthritis at the final follow-up.ConclusionsThis retrospective study is the first to assess the application of a curved incision on the anterior area of ankle with MIPO for the treatment of Pilon fractures, which achieves high functional recovery with a low complication rate. However, large randomized controlled trials comparing different approaches and fixation methods are still needed to conclusively identify the optimal treatment protocol.

Experimental Seismic Performance of Partly-Sliding Partition Walls

ABSTRACT Plasterboard partition walls typically used in commercial buildings are especially sensitive to earthquakes, with the onset of cosmetic damage initiating at small values of interstorey drift. The most common partition wall systems are constructed of gypsum board attached to either steel or timber framing which is fixed directly to the floor system at the top and bottom interfaces. This study investigates the seismic performance of a novel partly-sliding steel-framed partition system examined in the past and used by industry, with minor modifications incorporated within the partition detailing. This novel system involves removing top track anchors within the proximity of wall intersections, thus allowing the tracks to ‘bow’ out at these locations. In this study three full-scale specimens were subjected to quasi-static cyclic testing; two identical plane specimens and the third including a doorway. The specimens were built in a y-shape and angled at 30° to the direction of applied loading, which allowed bi-direction behaviour to be examined. The specimens included an acoustic/fire sealant. The progression of damage in a partition can be categorized by three sequential damage states associated with distinct levels of repair: superficial damage requiring cosmetic repair (damage state 1 (DS1)), damage requiring local repairs or replacement of only portions of the partition assembly (damage state 2 (DS2)), and severe damage requiring complete removal and replacement of the wall (damage state 3 (DS3)). Damage was first observed as cracking of the wallboard at the wall ends, at external junctions, and propagating from the corners of the door opening. The onset of DS1 and DS2 occurred simultaneously at a median in-plane drift of 0.29%. DS3 was not observable until the linings had been removed at the end of the tests. In addition to providing drift capacities, the force-displacement behaviour is also reported, the dissipated energy was computed, and the parameters of the Wayne–Stewart hysteretic model were fitted to the results. The specimen with the door opening behaved significantly different to the plane specimens: damage to the doorway specimen began as cracking of the wallboard propagating from the corners of the doorway following which the L- and Y-shaped junctions behaved independently, whereas damage to the plane specimens began as cracking of the wallboard at the top of the L-junction and wall system deformed as a single unit. The results suggest that bi-directional behaviour is important even if its impact cannot be directly quantified by this experiment. Damage to sealant implies that the bond between plasterboard and sealant is important for its seismic performance, and careful quality control is advised, as defects in the bond may significantly impact its ability to withstand seismic movement.

A longitudinal study of pre- and post-weaning tail damage in non-docked pigs

Tail-biting occurs pre-weaning, but literature on tail damage during lactation and on the development of damage over time is sparse, especially for non-docked piglets. We assessed the prevalence of tail damage in non-docked piglets in a commercial Danish piggery during the lactation and weaning period, and investigated the within-animal association of tail lesions pre- and post-weaning. Non-docked piglets (n = 741) from 51 loose-housed sows were individually marked and tracked from birth to 9 weeks (w9) of age. Tail damage was scored during lactation at w1 and w4, and once a week post-weaning (average weaning age 30 days) at w6 to w9. The within-animal association of tail damage before and after weaning was investigated at pig level using generalized mixed models. Tail damage was prevalent already pre-weaning. During the lactation period, the prevalence of tail lesions was 5% at w1 and 42% at w4, with the most prevalent score being ‘superficial damages’ (66.7%, score 1; pre-weaning scheme: 0 = no damage, 3 = tail wound). Post-weaning, 45% of pigs had a tail lesion at least once over the four assessments, with 16.7% of pigs having a tail lesion at least at two assessments. The majority of lesions were ‘minor scratches’ (34.2%, score 1; post-weaning scheme: 0 = no damage, 4 = wound – necrotic tail end) and a ‘scabbed wound’ (19.9%, score 3). The number of pigs with lesions as well as wound severity increased over time. More pigs had a tail wound at w8 (15%, P < 0.001 and < 0.01) and w9 (19%, P < 0.001 and < 0.001) compared to w6 (2.7%) and w7 (5.6%). Pigs with tail lesions pre-weaning (w1: OR 3.0, 95% CI 0.9 to 10.2; w4: OR 3.4, 95% CI 2.0 to 5.8) had a significantly higher risk of having a wound post-weaning, and pigs with lesions at w4 additionally were at a higher risk (OR 3.0, 95% CI 1.8 to 5.1) of having a lesion over several assessments. Females compared to castrated males had a significantly lower risk of having tail lesions at w1 (OR 0.3, 95% CI 0.1 to 0.8). Similarly, females were at a significantly lower risk (OR 0.5, 95% CI 0.4 to 0.9) of having a wound post-weaning, and tended to have a lower risk of having lesions over several assessments (OR 0.7, 95% CI 0.5 to 1.2). Our study confirmed that tail damage is prevalent already during the lactation period, and that pre-weaning tail damage is predictive of tail wounds post-weaning.

Impact of H-mode plasma operation on pre-damaged tungsten divertor tiles in ASDEX Upgrade

The effect of continued plasma exposure on two divertor target tiles intentionally damaged before installation was studied for ASDEX Upgrade H-mode discharge conditions. On one tile, made of molybdenum alloy (TZM), superficial melt damage was created in the GLADIS high heat flux test facility. To measure the influence of the resulting surface corrugations on erosion, the tile surface was subsequently covered with a 20 nm tungsten marker layer. A second tile, made of tungsten, was pre-damaged by exposure to 2 × 105 consecutive ELM-like heat pulses in the electron beam test facility JUDITH, which resulted in formation of an extended crack network. Both tiles were placed at the outer divertor target of ASDEX Upgrade using the DIM-II divertor manipulator and exposed to a series of 15 identical H-mode discharges. The surface state of both tiles was documented pre- and post-exposure using electron scanning microscopy. SEM analysis of the crack network’s microscopic structure did not reveal any additional damage created by plasma exposure but showed deposition of migrated wall materials inside shadowed areas. The erosion pattern of the W-marker layer revealed regions of net erosion as well as of net deposition in the corrugated melt zone. Net erosion up to complete removal of the W marker layer was found at elevated parts of the surface oriented towards the incident plasma flux whereas net deposition was found in corresponding shadowed areas. In contrast, the undamaged surface parts showed a uniform erosion pattern determined by incident plasma ion flux and temperature.

Tensile Behavior and Formability of Pre-Painted Steel Sheets

The present work aims at studying the tensile behavior and formability of pre-painted steel sheets. To this purpose, uniaxial tensile and hemispherical punch tests were performed in order to analyze the deformation behavior of pre-painted sheets under uniaxial stretching and biaxial balanced stretching conditions, respectively. Tests were interrupted in order to obtain different strain levels until fracture; at each strain level reached, the occurrence of superficial damages on the paint coating was detected; thinning of the different layers of the pre-painted sheet was also measured. It was observed that the degree of damage on the paint coating depends on the loading condition; in particular, under uniaxial stretching, the paint coating is able to follow the steel sheet during deformation up to the onset of the necking, whilst, under biaxial balanced stretching, coating exhibits superficial damages before fracture of the sheet.

Concrete Preliminary Damage Inspection by Classification of Terrestrial Laser Scanner Point Clouds through Systematic Threshold Definition

This paper presents a novel approach for automatic, preliminary detection of damage in concrete structures using ground-based terrestrial laser scanners. The method is based on computation of defect-sensitive features such as the surface curvature, since the surface roughness changes strongly if an area is affected by damage. A robust version of principal component analysis (PCA) classification is proposed to distinguish between structural damage and outliers present in the laser scanning data. Numerical simulations were conducted to develop a systematic point-wise defect classifier that automatically diagnoses the location of superficial damage on the investigated region. The method provides a complete picture of the surface health of concrete structures. It has been tested on two real datasets: a concrete heritage aqueduct in Brooks, Alberta, Canada; and a civil pedestrian concrete structure. The experiment results demonstrate the validity and accuracy of the proposed systematic framework for detecting and localizing areas of damage as small as 1 cm or less.

An archaeometallurgical study of Mixtec silver gold alloy foils from Tomb No. 7, Monte Alban, Oaxaca, México

This work evaluates four groups of silver gold alloy foil samples from Tomb No. 7 from Monte Albán, Oaxaca. These were classified as received according to coloration as LG1, LG2, LG3, and LG4. These samples were called silver gold alloy foils because of their main elemental composition. These were analyzed (without alterations) via optical microscopy, scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS). It was necessary to prepare them by focused ion beam (FIB) cross section to know their real microstructure and finally to test their indentation hardness (HIT) and indentation modulus (EIT) to measure mechanical properties. The experimental results revealed that silver gold alloys were cold-worked and annealed using a mixed technique of hammering with intermediate annealing for grain-size refinement. These were modified in their mechanical properties. The LG2 sample was the thinnest (27 μm) and hardest foil (HIT = 1781.7 MPa). It has the highest Au content (56.9 wt%) and the lowest Cu content (1.5 wt%) unlike LG4, which was the softest foil (HIT = 325.1 MPa). This sample showed non-recrystallized grains: This was the major superficial damage and led to a deficient work metal.

Submental intubation in oral and maxillofacial surgery: a systematic review 1986-2018.

Submental intubation is a low-risk alternative to tracheostomy when nasotracheal or orotracheal intubation is not appropriate. To improve the selection of patients and clinical outcomes we have explored published papers on submental intubation in oral and maxillofacial surgery, and included a proposal for a decision pathway. Systematic searches of PubMed, Scopus, and Cochrane databases for papers published between 1986 and 2018 yielded 116 eligible articles (one randomised controlled trial, 61 case series, 40 case reports, six surgical techniques, and eight letters) that included 2 229 patients. Measured outcomes were the indications, techniques, devices used, time taken to complete the procedure, and complications. Indications were trauma (81%), orthognathic surgery (15%), disease (2%), and cosmetic surgery (1%). Technical preferences were for a one-tube (84%) over a two-tube technique (6%), and a paramedian (52%) over a median incision (33%). The preferred device was a reinforced endotracheal tube (85%). The mean (range) intubation time was 10 (2-37) minutes. The complication rate was 7% (n=152), the most common being superficial skin infection (n=54), hypertrophic scarring (n=18), and damage to the tube apparatus (n=15). Submental intubation has minimal complications, takes a short time to do, and it is a useful alternative to tracheostomy in some oral and maxillofacial operations. More robust evidence regarding the selection of patients, modifications to the technique, and a comparison of risk with that of tracheostomy, are needed for further evaluation of its feasibility.

Scanning electron microscopy study of different one-piece foldable acrylic intraocular lenses after injection through microincisional cataract surgery cartridges.

To evaluate possible surface alterations of different models of one-piece foldable acrylic intraocular lenses (IOLs) after folding and ejecting process through 2.2-mm microincisional cataract surgery (MICS) cartridges. In this experimental laboratory study, the following IOLs were studied: Johnson&Johnson PCB00, HOYA iSert 251, Alcon AcrySof IQ SN60WF, Bausch&Lomb enVISTA MX-60. A total of 80 IOLs were analyzed. Twenty intraocular lenses of each type were studied: ten with a power of + 21 D ± 1 and ten with a power of + 28 D ± 1. IOLs were injected through a dedicated 2.2-mm MICS cartridge into a 50-mL vial containing 10mL of deionized water. After rinsing and metallization process, scanning electron microscopy images were acquired. All IOLs presented high-quality construction biomaterials. Some IOLs showed superficial scratches and tears on the optic surface, mainly positioned according to the direction of the stress induced by the folding process. In other cases, small superficial tears were seen in a more peripheral position. All lenses showed excellent surface quality. After folding and injection process some superficial scratches and tears of the IOL optic were detected in some models. Further studies are needed to assess the possible effects of those superficial damages on the optical quality of the IOLs.

Dietary threonine prevented stress-related mucosal diseases in rats.

Stress-related mucosal disease (SRMD), or stress ulceration, is a group of conditions ranging from stress-related superficial gastric mucosal damage to deep gastric ulcers that are primarily correlated with mucosal ischemia, and pharmacologic interventions that optimize tissue perfusion or preserve defensive mucus aim to decrease the occurrence of conditions, such as gastric acidity, or enhance gastric defenses. However, the identification of multifactorial pathogenesis may be effective in preventing SMRD, and the use of stress prophylaxis is generally preferred. Since threonine is a component in the polymerization and synthesis of gastric mucin and possibly enhanced defense actions and lignin may provide structural support for defense and antioxidative function, we hypothesized that dietary intake of threonine and/or lignin can enhance defense against SRMD. The water immersion-restraint stress (WIRS) was used in rats and additional groups were pretreated with threonine alone or the combination of threonine and lignin. Based on gross and microscopic evaluations, threonine alone or the combination of threonine and lignin, a natural antioxidant, significantly reduced the development of SRMD (P < 0.05). According to molecular explorations, the levels of inflammatory mediators, such as interleukin (IL)-8, IL-6, IL-1β, inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNF-α), and interferon gamma (IFN-γ), all of which are mediators that play a significant role in controlling WIRS, significantly decreased in the groups pretreated with either threonine alone or the combination of threonine and lignin (P < 0.01). WIRS significantly increased apoptosis in the stomach. However, the apoptotic index significantly decreased with threonine pretreatment. According to periodic acid Schiff staining results, the expression of gastric mucin was significantly preserved in groups pretreated with threonine but remarkedly decreased in the WIRS group. The gastric heme oxygenase-1 levels significantly increased in the group treated with threonine. In conclusion, the dietary intake of threonine or the combination of threonine and lignin is effective in preventing SRMD.

Influence of multiple laser impacts on thin leading edges of turbine blade

Laser shock peening is a mechanical surface improvement treatment used to enhance the fatigue life of critical components. This paper investigates the influence of multiple square laser impacts to study their special effect on the diverse mechanical behaviours of the thin leading edge surface of turbine blades. Most works existing in the literature have presented experimental investigations. The originality of our paper is to validate and numerically simulate the proposed model. Indeed, a 3D finite element method of a thin leading edge specimen, Ti–6Al–4V, of a turbine blade is numerically simulated using the ABAQUS software. The mechanical surface modifications (residual stresses, equivalent plastic strains and Johnson–Cook superficial damage) induced by the multiple square laser impact are examined in detail. The main purpose of this investigation is to determine the effects of single-sided and double-sided laser shock peening.