A 20-year-old man presented at our clinic with a primary complaint of irregular dentition and reverse bite. Clinical examination revealed skeletal Class III malocclusion with an anterior crossbite and a completely blocked #25 in the maxilla. Because he refused to receive orthognathic surgery and experienced only mild functional interference, a nonextraction treatment method was adopted. Space creation on the left upper arch was successfully performed using an open coil spring for molar distalization and the improved super-elastic Ti–Ni alloy wire (ISW) Multi-bends Edgewise Arch Wire (MEAW) technique. Furthermore, #25 was aligned completely. The Class III malocclusion was corrected using the ISW MEAW technique combined with Class III elastics on the lower arch. Treatment was completed in approximately 16 months and a satisfactory occlusion was achieved after active treatment.