Advancements in early warning, efficient evacuation, and previous experience with cyclones have largely restricted disaster casualties in the Sundarban delta in India and Bangladesh. Despite the limited loss of life, post-cyclone soil, inland water salinity, and loss of agriculture productivity remain among the impeding factors affecting people's lives. Two severe cyclones, cyclone Amphan, which hit on May 20, 2020, and cyclone Yaas, which hit the delta on May 28, 2021, caused significant damage to the life and livelihood of the local people. In this paper, we inquired into the mental health and socio-psychological aspects of cyclone Amphan and Yaas-induced water insecurity in the Indian Sundarban delta using both qualitative and quantitative research methods. The empirically derived data from Focus Group Discussions (N = 17; Number of participants = 157) and household surveys (N = 121) were subjected to various qualitative and quantitative analyses to understand the key determinants of post-cyclone water-induced mental health and well-being. Results suggest varying levels of stress and anxiety among the respondents, which include indecisiveness, general anxiety, fear of waterlessness, irritation, loss of self-esteem, and multiple other mental health issues. The FGD participants pointed out the severe impacts of the cyclones including increased seawater inundation, salinization of agricultural lands, flooding of the freshwater sources and increased water prices. Among all these impacts, seawater inundation and salinization of water and soil have the most long-lasting impact on the life and livelihood of local people. In the quantitative analysis, we observed that the perceived lack of fresh water, including both quality and quantity, alongside, the experience of water-borne diseases, loss of social relations, and loss of livelihood are the key determinants of the self-reported emotional stress of the respondents. In the lieu of existing knowledge gap on disaster-induced water insecurity and its impact on the mental health of affected people, the present research findings emphasize the need for resilient water structures on one side and socio-psychological counselling at the community level on the other side to ensure a sound recovery of the damaged resources as well as make the community a part of the recovery process that can improve their mental health.