Summary Page Research Articles

Modeling Consumer Footprints on Search Engines: An Interplay with Social Media

It is now well understood that social media plays an increasingly important role in consumers’ decision making. However, an overload of social media content in product search engines can hinder consumers from efficiently seeking information. We propose a structural econometric model to understand consumers’ preferences and costs on search engines to improve user experience under unstructured social media. Our model combines an optimal stopping framework with an individual-level random utility choice model and analyzes click behavior in conjunction with purchase choices. Our model accounts for three major constraints in a consumer’s decision-making process: (1) interdependency in decision making for different alternatives, (2) sequential arrival of information revealed by click-throughs, and (3) nonnegligible search cost. Our approach allows us to jointly estimate consumers’ heterogeneous preferences and search costs under the interplay of social media and search engines, and to predict search and purchase behavior for each consumer. We validate the model using an individual session-level data set of approximately seven million observations resulting in room bookings in 2,117 U.S. hotels. Interestingly, our analysis allows us to quantify the trade-off between consumers’ benefits and cognitive costs from using large-scale unstructured social media information during decision making. Our policy experiments show that providing a carefully curated digest of social media content during the earlier stages of consumer search (i.e., on the search results summary page) can lead to a 12.01% increase in the overall search engine revenue. The online appendix is available at https://doi.org/10.1287/mnsc.2017.2991 . This paper was accepted by Anandhi Bharadwaj, information systems.

An Excel Macro for Determining Allelic and Sequence Types of Bacterial Clones in Multilocus Sequence Typing.

BackgroundMultilocus sequence typing (MLST) was designed to overcome the low discriminatory power and poor reproducibility of previous molecular typing schemes, and it is useful for inter-laboratory, inter-regional, and inter-national comparison of pathogenic clones. MLST includes labor-intensive sequencing processes and meticulous allelic/sequence type (ST) determination processes, often prone to error. We developed a free automated MLST determination program (MLST typer) based on the Visual Basic for Applications macro, which runs on Microsoft Excel.MethodsMLST typer imports sequence data in the FASTA format, converts reverse complement counterparts of the reverse sequences, assembles forward and reverse-complement converted sequences, and returns allelic numbers for each gene and ST of each isolate. To evaluate the performance of MLST typer, we tested the sequence data from 200 clinical isolates, each consisting of seven housekeeping gene sequences, with a total of 1,400 allelic number determinations. The results were compared with manual assessment.ResultsMLST typer comprises three worksheets: the Main page, Result page, and Summary page. The Main page console operates the process according to user-specified parameters. The Result and Summary pages provide the allelic type and ST determinations. It took approximately 12 minutes to analyze the sequence data from 200 clinical isolates. Compared with manual assessment, the rate of correct identification was 97.2% (1,361/1,400).ConclusionsMLST typer can be widely used for epidemiological studies owing to its thoroughness in repetitive functions, good compatibility with FASTA type data files, and easy-to-understand outputs for allelic and ST determinations.

BRENDA in 2019: a European ELIXIR core data resource.

The BRENDA enzyme database (www.brenda-enzymes.org), recently appointed ELIXIR Core Data Resource, is the main enzyme and enzyme-ligand information system. The core database provides a comprehensive overview on enzymes. A collection of 4.3 million data for ∼84 000 enzymes manually evaluated and extracted from ∼140 000 primary literature references is combined with information obtained by text and data mining, data integration and prediction algorithms. Supplements comprise disease-related data, protein sequences, 3D structures, predicted enzyme locations and genome annotations. Major developments are a revised ligand summary page and the structure search now including a similarity and isomer search. BKMS-react, an integrated database containing known enzyme-catalyzed reactions, is supplemented with further reactions and improved access to pathway connections. In addition to existing enzyme word maps with graphical information of enzyme specific terms, plant word maps have been developed. They show a graphical overview of terms, e.g. enzyme or plant pathogen information, connected to specific plants. An organism summary page showing all relevant information, e.g. taxonomy and synonyms linked to enzyme data, was implemented. Based on a decision by the IUBMB enzyme task force the enzyme class EC 7 has been established for ‘translocases’, enzymes that catalyze a transport of ions or metabolites across cellular membranes.

Evaluation of ASCE 7 equations for designing acceleration sensitive nonstructural components using data from instrumented buildings

The following correction should be made in Anajafi and Medina1: In the Summary (page 1075 lines 7–10) and Conclusion (page 1092 lines 35–38) sections of this paper it is stated that the in-structure and the component amplification factors are a function of the ratio of NSC period to the supporting building modal periods, the ground motion intensity, and the NSC location. The expression “the in-structure and” should be removed from this statement, i.e., it should state that the component amplification factor is a function of the ratio of NSC period to the supporting building modal periods, the ground motion intensity, and the NSC location.

Using the Candida Genome Database.

Studying Candida biology requires access to genomic sequence data in conjunction with experimental information that together provide functional context to genes and proteins, and aid in interpreting newly generated experimental data. The Candida Genome Database (CGD) curates the Candida literature, and integrates functional information about Candida genes and their products with a set of analysis tools that facilitate searching for sets of genes and exploring their biological roles. This chapter describes how the various types of information available at CGD can be searched, retrieved, and analyzed. Starting with the guided tour of the CGD Home page and Locus Summary page, this unit shows how to navigate the various assemblies of the C. albicans genome, how to use Gene Ontology tools to make sense of large-scale data, and how to access the microarray data archived at CGD, as well as visualize high-throughput sequencing data through the use of JBrowse.

PiMP my metabolome: an integrated, web-based tool for LC-MS metabolomics data.

SummaryThe Polyomics integrated Metabolomics Pipeline (PiMP) fulfils an unmet need in metabolomics data analysis. PiMP offers automated and user-friendly analysis from mass spectrometry data acquisition to biological interpretation. Our key innovations are the Summary Page, which provides a simple overview of the experiment in the format of a scientific paper, containing the key findings of the experiment along with associated metadata; and the Metabolite Page, which provides a list of each metabolite accompanied by ‘evidence cards’, which provide a variety of criteria behind metabolite annotation including peak shapes, intensities in different sample groups and database information.Availability and implementationPiMP is available at http://polyomics.mvls.gla.ac.uk, and access is freely available on request. 50 GB of space is allocated for data storage, with unrestricted number of samples and analyses per user. Source code is available at https://github.com/RonanDaly/pimp and licensed under the GPL.Supplementary information Supplementary data are available at Bioinformatics online.

Using the MEROPS Database for Investigation of Lysosomal Peptidases, Their Inhibitors, and Substrates.

This chapter describes how to retrieve data on lysosomal peptidases from the MEROPS database for proteolytic enzymes, their substrates and inhibitors ( http://merops.sanger.ac.uk ). Features described in this chapter include the summary page, pages for structure, interactions with inhibitors, substrates, literature and involvement in physiological pathways, and how to download data from the MEROPS FTP site. The lysosomal peptidase legumain is used as an example.

An Essay on Current Quintilian Studies in English, With a Select Bibliography of Items Published Since 1990

An Essay on Current Quintilian Studies in English, With a Select Bibliography of Items Published Since 1990

P036: A clinical decision support intervention to increase usage of probenecid in the ED

Introduction: In certain circumstances, skin and soft tissue infections are managed with intravenous (IV) antibiotics. In our center, patients initiated on outpatient IV antibiotics are followed up by a home parental therapy program the following day. A significant number of these patients require a repeat visit to the ED because of clinic hours. Probenecid is a drug that can prolong the half-life of certain antibiotics (such as cefazolin) and can therefore avoid a repeat ED visit, reducing health care costs and improve ED capacity. Our goal was to increase probenecid usage in the ED in order to optimize management of skin and soft tissue infections (SSTI) in the ED. The primary outcome was to compare the usage of probenecid in the pre and post-intervention phase. Secondary outcomes were to compare revisit rates between patients receiving cefazolin alone vs cefazolin + probenecid. Methods: Using administrative data merged with Computerized Physician Order Entry (CPOE), we extracted data 90 days pre- and 90 post-intervention (February 11, 2015 to August 11, 2015). The setting for the study is an urban center (4 adult ED’s with an annual census of over 320,000 visits per year). Our CPOE system is fully integrated into the ED patient care. The multi-faceted intervention involved modifying all relevant SSTI order sets in the CPOE system to link any cefazolin order with an order for probenecid. Physicians and nurses were provided with a 1 page summary of probenecid (indications, contra-indications, pharmacology), as well as decision support with the CPOE. Any patients who were receiving outpatient cefazolin therapy were included in the study. Results: Our analysis included 2512 patients (1148 and 1364 patients in the pre/post phases) who received cefazolin in the ED and were discharged during the 180 day period. Baseline variables (gender, age, % admitted) and ED visits were similar in both phases. In the pre-intervention phase 30.2% of patients received probenecid and in the post-intervention phase 43.0%, for a net increase of 12.8% (p=<0.0001). Patients who received probenecid had a 2.2% (11.4% vs 13.6%, p=0.014) lower re-visit rate in the following 72H. Conclusion: We have implemented a CPOE based clinical decision support intervention that demonstrated significant increase in probenecid usage by emergency physician and resulted in a decrease in ED revisits. This intervention would result in health care cost-savings.

Tweeting links to Cochrane Schizophrenia Group reviews: a randomised controlled trial

ObjectiveTo assess the effects of using health social media on web activity.DesignIndividually randomised controlled parallel group superiority trial.SettingTwitter and Weibo.Participants170 Cochrane Schizophrenia Group full reviews with an abstract and plain...

Show Me My Health Plans: a study protocol of a randomized trial testing a decision support tool for the federal health insurance marketplace in Missouri.

BackgroundThe implementation of the ACA has improved access to quality health insurance, a necessary first step to improving health outcomes. However, access must be supplemented by education to help individuals make informed choices for plans that meet their individual financial and health needs.Methods/DesignDrawing on a model of information processing and on prior research, we developed a health insurance decision support tool called Show Me My Health Plans. Developed with extensive stakeholder input, the current tool (1) simplifies information through plain language and graphics in an educational component; (2) assesses and reviews knowledge interactively to ensure comprehension of key material; (3) incorporates individual and/or family health status to personalize out-of-pocket cost estimates; (4) assesses preferences for plan features; and (5) helps individuals weigh information appropriate to their interests and needs through a summary page with “good fit” plans generated from a tailored algorithm. The current study will evaluate whether the online decision support tool improves health insurance decisions compared to a usual care condition (the healthcare.gov marketplace website). The trial will include 362 individuals (181 in each group) from rural, suburban, and urban settings within a 90 mile radius around St. Louis. Eligibility criteria includes English-speaking individuals 18–64 years old who are eligible for the ACA marketplace plans. They will be computer randomized to view the intervention or usual care condition.DiscussionPresenting individuals with options that they can understand tailored to their needs and preferences could help improve decision quality. By helping individuals narrow down the complexity of health insurance plan options, decision support tools such as this one could prepare individuals to better navigate enrollment in a plan that meets their individual needs. The randomized trial was registered in clinicaltrials.gov (NCT02522624) on August 6, 2015.

How to Use the Candida Genome Database.

Studying Candida biology requires access to genomic sequence data in conjunction with experimental information that provides functional context to genes and proteins. The Candida Genome Database (CGD) integrates functional information about Candida genes and their products with a set of analysis tools that facilitate searching for sets of genes and exploring their biological roles. This chapter describes how the various types of information available at CGD can be searched, retrieved, and analyzed. Starting with the guided tour of the CGD Home page and Locus Summary page, this unit shows how to navigate the various assemblies of the C. albicans genome, how to use Gene Ontology tools to make sense of large-scale data, and how to access the microarray data archived at CGD.

Francophone Cultures through Film by Nabil Boudraa, Cécile Accilien

Reviews 293 filles Marie au moment du baptême” (xix). To avoid any confusion, Morrissette explains that“les prénoms Marie et Joseph ne font pas partie du prénom au quotidien. Ainsi, depuis ma naissance, on m’appelle simplement Vincent”(xx). In a similar manner , Blood explains her family’s background and how despite her grandmother Bernadette Plouffe’s decision to stay in New York to marry an American Anglophone, her family maintained tight connections with its Francophone family in Saint-Félixde -Valois, a small town to the east of Montreal. Canisius College (NY) Eileen M. Angelini Boudraa,Nabil,and Cécile Accilien. Francophone Cultures through Film. Newburyport : Focus, 2014. ISBN 978-1-58510-311-9. Pp. 237. $33. In a time where programs are looking to continue to diversify course offerings to increase intercultural competency among students, to treat the idea of texts in a broader way, and to present the diversity of Francophone cultures, this book fills a particular niche. Demonstrative of the need that Francophone Cultures through Film addresses, there are limited options for textbooks that survey a variety of Francophone cultures and simultaneously focus on film as a medium as this textbook does. Though not geographically comprehensive, it presents a wide variety of contexts (North and Sub-Saharan Africa, the Caribbean, Southeast Asia, Québec, and Europe) through films from 1965 to 2009. The approach taken is engaging and content-based, guiding intermediate and upper-level students toward both visual and cultural literacy by inviting them to analyze films through a focus on conversation, reading, and writing activities. The authors provide additional pedagogical suggestions, such as having students write film reviews for each unit and keep an ongoing film journal in order to foster both reflection and critical analysis. The thematic organization of this textbook (colonialism, independence, cultural diversity, immigration and exile, women’s issues) allows for its use as a primary or supplemental text in a variety of courses. Further, for instructors focusing on a particular theme or time period, individual sections can be purchased for course packets. The book begins with cinematic vocabulary, a list of important film festivals and awards, and a list of relevant acronyms. Each unit has preand post-viewing activities, a glossary of important terms used in each film, a country information summary page, short biographies of directors and main actors, an interview or other related text, and a suggested bibliography. Individuals incorporating films into literature-focused courses will find these interviews and suggested literary pairings particularly useful. However, for instructors wishing to include grammatical revision or translation in their courses, this textbook will need to be supplemented with other materials. Issues of access to films may remain an issue, but this has been mitigated by the authors who have selected films that are popular in the United States. Further, the authors and publisher provide information regarding where such films may be purchased or rented by students and instructors and offer the suggestion of organizing a film festival alongside the course in which the textbook is to be used. Outside of courses, this text may prove to be a valuable resource for those organizing film nights for French clubs or French and Francophone film festivals. The potential cost issues for students renting or purchasing films is also mitigated by the affordability of the textbook itself. University of South Dakota Kris Aric Knisely Oukada, Larbi, Didier Bertrand, and Janet Solberg. Controverses. 3rd ed. Boston: Cengage, 2016. ISBN 13 978-1-305-10578-2. Pp. 293. $150. Designed for students at the intermediate level, this eight-chapter text presents a variety of exercises that help students develop more sophisticated levels of oral and written expression. The materials available include a text (manuel), a Student Activities Manual (cahier d’activités), and online supersite. The bulk of grammar review is contained in the Student Activities Manual; most of the text is organized around contemporary and controversial topics such as globalization, immigration, and gender equality. The chapters are designed to encourage students to examine these topics from various points of view as they acquire the skills necessary to discuss and write about each topic.An interesting and unique aspect to Controverses is...

Temporal information searching behaviour and strategies

Temporal aspects have been receiving a great deal of interest in Information Retrieval and related fields. Although previous studies have proposed, designed and implemented temporal-aware systems and solutions, understanding of people’s temporal information searching behaviour is still limited. This paper reports the findings of a user study that explored temporal information searching behaviour and strategies in a laboratory setting. Information needs were grouped into three temporal classes (Past, Recency, and Future) to systematically study their characteristics. The main findings of our experiment are as follows. (1) It is intuitive for people to augment topical keywords with temporal expressions such as history, recent, or future as a tactic of temporal search. (2) However, such queries produce mixed results and the success of query reformulations appears to depend on topics to a large extent. (3) Search engine interfaces should detect temporal information needs to trigger the display of temporal search options. (4) Finding a relevant Wikipedia page or similar summary page is a popular starting point of past information needs. (5) Current search engines do a good job for information needs related to recent events, but more work is needed for past and future tasks. (6) Participants found it most difficult to find future information. Searching for domain experts was a key tactic in Future search, and file types of relevant documents are different from other temporal classes. Overall, the comparison of search across temporal classes indicated that Future search was the most difficult and the least successful followed by the search for the Past and then for Recency information. This paper discusses the implications of these findings on the design of future temporal IR systems.

250. Electronic Medical Record-Based Transition Planning Tool for Children & Youth With Special Health Care Needs: A Continuous Quality Improvement Project to Increase Provider Satisfaction and Preference

Purpose: Evidence-based methods to promote transition from pediatric to adult-based care for youth with special health care needs are needed. While the use of electronic medical record (EMR) based planning tools to facilitate transition by pediatric providers is promising, evidence that providers will use these tools is lacking. A health care transition (HCT) transition planning tool (TPT), designed to identify and help rectify gaps in knowledge/ skills needed by patients tomanage their disease in preparation for HCT from pediatric to adult care, was built into the EMR at a large children’s hospital. Use during the first 21 months (March 2012November 2013) was lower than expected as providers found the TPT 1.0 difficult to locate in the EMR and cumbersome to use. A streamlined, user-friendly upgrade from TPT 1.0 (TPT version 2.0) was introduced in December 2013. This quality improvement project will evaluate provider satisfaction with and preference for the improved TPT. Methods: Health care providers (physicians, nurses, social workers, and care navigators) working with 16-25 year-olds in four sub-specialty services (Cardiology, Hematology, Physiatry, and Retrovirology) consented to participate in a continuous quality improvement project to evaluate the implementation of an EMR-based TPT. Clinics volunteered because they serve youth who experience increased morbidity and mortality associated with inadequate transition from pediatric to adult health care. Providers were trained to use TPT 1.0 and received ongoing technical assistance. Using Plan-Do-Study-Act (PDSA) methods, feedback from providers prompted the development of TPT 2.0, which included the addition of a transition button on the EMR navigation pane, a flow sheet reporting the patient’s transition planning progress, and a simplified user interface with fewer clicks needed to access the tool. Providers (n1⁄417) completed a self-administered survey in November 2013 before TPT 2.0 was introduced and a second survey (n1⁄416) 7 months later (July 2014). Both surveys assessed TPT use, including barriers, and satisfaction with the TPT. In addition, the second survey asked providers to indicate which version (TPT 1.0 or TPT 2.0) they preferred. Results: Improved satisfaction was reported in ease of use (80% versus 67% for TPT 2.0 and 1.0, respectively) and accessibility of the tool (80% versus 58%), the summary page to help follow patients through the transition process (87% versus 73%), and the time it takes to utilize the tool in clinic (67% versus 42%). Despite taking less time to use, 63% (10/15) said they did not use TPT 2.0 as often as they wanted, citing time constraints in busy clinics as the primary reason. One clinic increased efficiency by assigning social workers to use the tool after clinic sessions. 100% of study providers stated they preferred using TPT 2.0 over TPT 1.0. Conclusions: In a group of providers motivated by the high morbidity and mortality associated with poor health care transition, there was increased satisfaction and preference for TPT 2.0, facilitated by incorporating their recommendations to improve the tool. Provider satisfaction and preference for this upgraded tool is expected to facilitate health care transition planning. Sources of Support: Funded by HRSA and Texas Department of State Health Services.

User Evaluation of the Fitness-to-Drive Screening Measure

ABSTRACTAims: The Fitness-to-Drive Screening Measure (FTDS) enables a proxy rater, such as a family member, to identify at-risk older drivers. This study addressed user evaluation of the web-based FTDS including the keyform (summary page) and recommendations. Methods: Eight participants reviewed the refined web-based measure, and rated the clarity, usefulness, understandability, and meaningfulness of the FTDS. We captured participants’ comments on the FTDS along with visual analog scale (VAS) ratings. Results: Overall, participants positively rated the FTDS as user-friendly, useful, and acceptable; an evaluation supported by the VAS rating (mean = 9.13, SD ± 1.10). Conclusions: Future research will include monitoring end-user satisfaction via an anonymous on-line survey.

Developing empirically supported theories of change for housing investment and health

The assumption that improving housing conditions can lead to improved health may seem a self-evident hypothesis. Yet evidence from intervention studies suggests small or unclear health improvements, indicating that further thought is required to refine this hypothesis. Articulation of a theory can help avoid a black box approach to research and practice and has been advocated as especially valuable for those evaluating complex social interventions like housing. This paper presents a preliminary theory of housing improvement and health based on a systematic review conducted by the authors. Following extraction of health outcomes, data on all socio-economic impacts were extracted by two independent reviewers from both qualitative and quantitative studies. Health and socio-economic outcome data from the better quality studies (n = 23/34) were mapped onto a one page logic models by two independent reviewers and a final model reflecting reviewer agreement was prepared. Where there was supporting evidence of links between outcomes these were indicated in the model. Two models of specific improvements (warmth & energy efficiency; and housing led renewal), and a final overall model were prepared. The models provide a visual map of the best available evidence on the health and socio-economic impacts of housing improvement. The use of a logic model design helps to elucidate the possible pathways between housing improvement and health and as such might be described as an empirically based theory. Changes in housing factors were linked to changes in socio-economic determinants of health. This points to the potential for longer term health impacts which could not be detected within the lifespan of the evaluations. The developed theories are limited by the available data and need to be tested and refined. However, in addition to providing one page summaries for evidence users, the theory may usefully inform future research on housing and health.

Trade marks for the lay person and a good brush-up for the practitioner

This section is dedicated to the review of ideas, articles, books, films and other media. It will include replies (and rejoinders) to articles, the evaluation of new ideas or proposals, and reviews of books and articles both directly and indirectly related to intellectual property law. In the present world there is no shortage of information. Quite the opposite: practitioners and academics alike find themselves flooded with primary and secondary sources. Accessing a case is no longer difficult, and the main challenge lies in not wasting time and getting the right information and dealing effectively with complexity. In fact, that challenge has increased with the overabundance of data. At the same time, reading through a case to find its relevant and innovative part requires effort, even for the trained eye. In 2006, Dirk Visser produced a very useful little book entitled Trade Mark Case Law: ECJ: One Page Summaries (deLex 2006)....

Using Verification Planner to Track the Verification Process

This paper will discuss how we integrated Verification Planner in our verification environment to generate better reports that can be used to track the progress of verification with the project manager. Using Verification Planner we were able to add coverage information to the Verification IP’s Excel based verification plans. We can then take advantage of Excel to generate better reports. Using a top-level plan, we were able to generate a summary page that could be shared with project manager, giving them the information they needed.

Using a web-based decision support intervention to facilitate patient-physician communication at prostate cancer treatment discussions

Purpose: To measure the preferences and values of men newly diagnosed with prostate cancer (PC) using a web-based decision support technology—the Decision Support Intervention-Prostate Cancer (DSI-PC). Methods: Health information seeking behaviour, factors having an influence on the treatment decision, decision control, and preferred treatment were recorded by the DSI-PC program prior to the treatment consultation. A summary page of responses was provided to each patient to use at treatment discussions. Measures of decision control and decision conflict were measured prior to the treatment discussion, and following a treatment decision. Patient satisfaction was measured after a treatment decision had been made. Results: Forty-nine men completed the DSI-PC program prior to their treatment discussion. Sixty-one per cent shared the summary sheet with their physician/s when discussing treatment options. The majority (63%) of patients wanted access to in-depth or detailed information. Impact of treatment on survival, urinary function, bowel function, and physician’s treatment recommendation were the four factors having the most influence on patients’ treatment decisions. Patients reported high levels of satisfaction with their treatment decision, and involvement in treatment decision making (TDM). Levels of decision conflict were significantly lower (p < 0.001) after a treatment decision was made, and men reported assuming a significantly more active role in TDM than originally preferred (p = 0.038). Conclusions: Results suggest that the DSI-PC intervention may be a useful tool to help patients identify and communicate their values and preferences to physicians at the time of treatment discussions. Key words: prostate cancer, patient-physician communication, decision support intervention