Let $\mathscr{M}_{(2,1)}(N)$ be the infimum of the largest sum-free subset of any set of $N$ positive integers. An old conjecture in additive combinatorics asserts that there is a constant $c=c(2,1)$ and a function $\omega(N)\to\infty$ as $N\to\infty$, such that $cN+\omega(N)<\mathscr{M}_{(2,1)}(N)<(c+o(1))N$. The constant $c(2,1)$ is determined by Eberhard, Green, and Manners, while the existence of $\omega(N)$ is still wide open. In this paper, we study the analogous conjecture on $(k,\ell)$-sum-free sets and restricted $(k,\ell)$-sum-free sets. We determine the constant $c(k,\ell)$ for every $(k,\ell)$-sum-free sets, and confirm the conjecture for infinitely many $(k,\ell)$.
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