Sulfur Interactions Research Articles

Synthetic and structural studies of heteroleptic platinum(II) and palladium(II) complexes containing thiacrown and monodentate phosphane ligands

We wish to report the syntheses, spectroscopic, and structural properties for six new Pt(II) and Pd(II) heteroleptic complexes containing the monodentate phosphane ligands PTA (1,3,5-triaza-7-phosphaadamantane) or PMe3 (trimethylphosphane) and the crown trithioether [9]aneS3 (1,4,7-trithiacyclononane). All six reported complexes have the general formula [M([9]aneS3)(P2)](PF6)2 or [M([9]aneS3)(P)(Cl)](PF6) where M=Pt(II) or Pd(II) and P is the monodentate phosphane ligand. All six complexes form similar structures in which the metal center is surrounded by two sulfur atoms from the trithioether ligand and a cis arrangement of either the two phosphorus donors or the chlorido and phosphorus donor. The third sulfur from the [9]aneS3 interacts with the metal at a greater distance (2.711(2)Å–3.078(8)Å), resulting in elongated square pyramidal geometries. These axial distances are controlled by the donor abilities of the phosphane ligand with PTA and PMe3 serving as stronger donors. The two chlorido complexes show longer metal–sulfur interactions, consistent with the strong donor properties of the anionic chlorido ligand. Although the symmetrical bis complexes display typical 1H and 13C NMR behavior in the [9]aneS3 region, the less symmetrical chlorido complexes show a more complex pattern in their spectra. The 195Pt NMR chemical shifts are consistent with the presence of [S2P2+S1] or [S2PCl+S1] coordination environments.

Supramolecular oligothiophene microfibers spontaneously assembled on surfaces or coassembled with proteins inside live cells.

During the last few decades, multifunctional nano- and microfibers made of semiconducting π-conjugated oligomers and polymers have generated much interest because of a broad range of applications extending from sensing to bioelectronic devices and (opto)electronics. The simplest technique for the fabrication of these anisotropic supramolecular structures is to let the molecules do the work by spontaneous organization driven by the information encoded in their molecular structure. Oligothiophenes-semiconducting and fluorescent compounds that have been extensively investigated for applications in thin-film field-effect transistors and solar cells and to a lesser extent as dyes for fluorescent labeling of proteins, DNA, and live cells-are particularly suited as building blocks for supramolecular architectures because of the peculiar properties of the thiophene ring. Because of the great polarizability of sulfur outer-shell electrons and the consequent facile geometric deformability and adaptability of the ring to the environment, thiophene can generate multiple nonbonding interactions to promote non-covalent connections between blocks. Furthermore, sulfur can be hypervalent, i.e., it can accommodate more than the eight electrons normally associated with s and p shells. Hypervalent oligothiophene-S,S-dioxides whose oxygen atoms can be involved in hydrogen bonding have been synthesized. These compounds are amphiphilic, and some of them are able to spontaneously cross the membrane of live cells. Hypervalent nonbonding interactions of divalent sulfur, defined as weak coordination to a proximate nitrogen or oxygen, have also been invoked in the solid-state packing of many organic molecules and in the architecture of proteins. In this Account, we describe two different types of thiophene-based building blocks that can induce the spontaneous formation of nanostructured microfibers in very different environments. The first, based on the synthesis of "sulfur-overrich" hexamers and octamers, leads to surface-independent self-assembly of microfibers-helical or rodlike depending on the groups attached to the same identical inner core-that are crystalline, fluorescent, and conductive and display chirality despite the lack of chiral carbon atoms on the building blocks. Supramolecular polymorphic microfibers are also formed, and they are characterized by very different functional properties. The second, based on a rigid oligothiophene-S,S-dioxide, leads to coassembled protein-oligothiophene microfibers that are physiologically formed inside live cells. The oligothiophene-S,S-dioxide can indeed spontaneously cross the membrane of live cells and be directed toward the perinuclear region, where it is recognized and incorporated by specific peptides during the formation of fibrillar proteins without being harmful to the cells. Coassembled oligothiophene-protein microfibers are progressively formed through a cell-mediated physiological process. Thanks to the oligothiophene blocks, the microfibers possess fluorescence and charge-conduction properties. By means of fluorescence imaging, we demonstrated that various types of live cells seeded on these microfibers were able to internalize and degrade them, experiencing in turn different effects on their morphology and viability, suggesting a possible use of the microfibers as multiscale biomaterials to direct cell behavior. On the whole, our results show the great versatility of oligothiophene building blocks and allow us to foresee that their capabilities of spontaneous assembly in the most different environments could be exploited in much more exciting research fields than those explored to date.

Molecular-level insights of early-stage prion protein aggregation on mica and gold surface determined by AFM imaging and molecular simulation

By in situ time-lapse AFM, we investigated early-stage aggregates of PrP formed at low concentration (100ng/mL) on mica and Au(111) surfaces in acetate buffer (pH 4.5). Remarkably different PrP assemblies were observed. Oligomeric structures of PrP aggregates were observed on mica surface, which was in sharp contrast to the multi-layer PrP aggregates yielding parallel linear patterns observed Au(111) surface. Combining molecular dynamics and docking simulations, PrP monomers, dimers and trimers were revealed as the basic units of the observed aggregates. Besides, the mechanisms of the observed PrP aggregations and the corresponding molecular-substrate and intermolecular interactions were suggested. These interactions involved gold–sulfur interaction, electrostatic interaction, hydrophobic interaction, and hydrogen binding interaction. In contrast, the PrP aggregates observed in pH 7.2 PBS buffer demonstrated similar large ball-like structures on both mica and Au(111) surfaces. The results indicate that the pH of a solution and the surface of the system can have strong effects on supramolecular assemblies of prion proteins. This study provides in-depth understanding on the structural and mechanistic nature of PrP aggregation, and can be used to study the aggregation mechanisms of other proteins with similar misfolding properties.

Intramolecularly Sulfur-Stabilized Silicon Cations with Chiral Binaphthyl Backbones: Synthesis of Three Different Motifs and Their Application in Enantioselective Diels–Alder Reactions

The formation and 29Si NMR spectroscopic characterization of silicon cations that are intramolecularly stabilized by a dialkyl thioether are described. The chemical stability of the silicon–sulfur Lewis pair and, hence, the viability of the approach, were probed with a 2-[(alkylthio)methyl]phenyl-substituted hydrosilane as a proxy before three different motifs with chiral binaphthyl backbones were prepared in multistep sequences. The degree of shielding of the silicon atom in these cations was found to depend on the substitution pattern at the silicon atom and the ring size generated by the silicon–sulfur interaction. These sulfur-stabilized silicon cations are sufficiently reactive to promote Diels–Alder reactions of cyclohexa-1,3-diene with various dienophiles; the same set of reactions with cyclopentadiene is also reported. One of the three chiral Lewis acids induces low, but promising, enantioselectivity, and 24% ee is the highest value so far obtained with a cationic tetracoordinate silicon catalyst.

Effect of chromium–sulphur interactions on decarburisation of levitated Fe–C alloy droplets by CO2–Ar gas mixtures

This study provides an evaluation of the influence of chromium and sulphur on the decarburisation kinetics of Fe–Cr–C alloy droplets when exposed to argon gas mixtures containing carbon dioxide as the oxidant. For droplets containing the same amount of surface active sulphur, it was found that the decarburisation rate of iron–chromium droplets was substantially faster than that of chromium free alloys. This enhanced rate can be explained in terms of the attractive interaction between chromium and sulphur, which results in a decrease in the number of surface sites occupied by sulphur. An appropriate rate equation has been developed to characterise this behaviour. The findings from this work have beneficial implications with respect to the preferential oxidation of carbon rather than chromium when stainless steel is refined with argon–carbon dioxide gas mixtures.

Direct Observation of the Redistribution of Sulfur and Polysufides in Li–S Batteries During the First Cycle by In Situ X‐Ray Fluorescence Microscopy

The demands on low cost and high energy density rechargeable batteries for both transportation and large-scale stationary energy storage are stimulating more and more research toward new battery systems. Since sulfur is an earth-abundant material with low cost, research on the high energy density Li–S batteries (2600 W h kg⁻¹) are getting more and more attention. The reactions between sulfur and lithium during charge–discharge cycling are quite complicated, going through multiple electron transfer process associated with chemical and electrochemical equilibrium between long- and short-chain polysulfide Li₂Sx intermediates (1 < x ≤ 8). It is reported that the long-chain polysulfides can be dissolved into electrolyte with aprotic organic solvents and migrated to the Li anode side. This so-called “shuttle effect” is believed to be the main reason for capacity loss and low columbic efficiency of the Li–S batteries. In the past few years, a great deal of efforts have been made on how to overcome the problem of polysulfide dissolution through new sulfur electrode construction and cell designs, as well as the modification of the electrolyte. Although it has been reported by several publications that some Li–S cells can sustain more than a thousand cycles based on the thin film electrodemore » configurations, the long-term cycling stability is still one of the major barriers for the real application of Li–S batteries. More in-depth studies on the fundamental understanding of the sulfur reaction mechanism and interactions among the different polysulfide species, the electrolyte and the electrodes are still greatly needed. Various in situ techniques have been developed and applied to study the mechanism of the sulfur chemistry in Li–S batteries during electrochemical cycling, such as transmission X-ray microscopy (TXM), X-ray absorption spectroscopy (XAS), X-ray diffraction (XRD), UV–visible spectroscopy, and electron paramagnetic resonance (EPR). The applications of these characterization techniques have demonstrated their power in probing the structure changes, morphology evolutions, and coordination of sulfur and polysulfides with the electrolyte in Li–S cells, providing complementary information to each other thus enhancing the understanding in Li–S battery systems. In this communication, in situ X-ray fluorescence (XRF) microscopy was combined with XAS to directly probe the morphology changes of Li–S batteries during first cycle. The morphology changes of the sulfur electrode and the redistribution of sulfur and polysulfides were monitored in real time through the XRF images, while the changes of the sulfur containing compounds were characterized through the XAS spectra simultaneously. In contrast to other studies using ex situ or single characterization technique as reported in the literatures, the in situ technique used in this work has the unique feature of probing the Li–S cell under operating conditions, as well as the combination of XRF imaging with spectroscopy data. By doing this, the morphology evolution and redistribution of specific sulfur particles during cycling can be tracked and identified at certain locations in a real time. In addition, this technique allows us to select the field-of-view (FOV) area from micrometer to centimeter size, providing the capability to study the Li–S reactions not just at the material level, but also at the electrode level. This is very important for both understanding Li–S chemistry and designing effective strategies for Li–S batteries.« less

π-Stacked structure of thiadiazolo-fused benzotriazinyl radical: Crystal structure and magnetic properties

A novel benzotriazinyl radical with a 2,1,3-thiadiazolo fused ring (1,3-diphenyl-1,2-dihydro-[1,2,5]thiadiazolo[3′,4′:3,4]benzo[1,2-e]-1,2,4-triazine-2-yl; NSNBT) was prepared and characterized by ESR measurement, cyclic voltammetry, and X-ray crystallographic analysis. By a detailed study of bond lengths and angles, it was found that the molecular structure of NSNBT borrows characteristics both from 2,1,3-benzothiadiazole and from the unsubstituted benzotriazinyl radical, and the central phenyl ring presents a phenanthrene-type bond alternation. Molecules were shown to be arranged in a π-stacked columnar structure, with columns connected to each other through sulfur–sulfur interactions in the crystal. It exhibited strong antiferromagnetic interactions (J/kB=−434K) derived from its dimer structure.

A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design.

Electron deficient, bivalent sulfur atoms have two areas of positive electrostatic potential, a consequence of the low-lying σ* orbitals of the C-S bond that are available for interaction with electron donors including oxygen and nitrogen atoms and, possibly, π-systems. Intramolecular interactions are by far the most common manifestation of this effect, which offers a means of modulating the conformational preferences of a molecule. Although a well-documented phenomenon, a priori applications in drug design are relatively sparse and this interaction, which is often isosteric with an intramolecular hydrogen-bonding interaction, appears to be underappreciated by the medicinal chemistry community. In this Perspective, we discuss the theoretical basis for sulfur σ* orbital interactions and illustrate their importance in the context of drug design and organic synthesis. The role of sulfur interactions in protein structure and function is discussed and although relatively rare, intermolecular interactions between ligand C-S σ* orbitals and proteins are illustrated.

Formation of WS&lt;sub&gt;2&lt;/sub&gt;/MoS&lt;sub&gt;2&lt;/sub&gt; Particles with Nanoscale Layers for Multipurpose Application

Multipurpose tungsten and molybdenum disulfides with nanoscale layered structure formation are studied. Morphology and particle size distribution of initial tungsten and molybdenum nanopowders produced by electrical explosion of wire and used in metal disulfides synthesis are presented. Mechanism of metal nanopowder and elementary sulphur interaction in SHS condition with WS2/MoS2 nanoscale layered particles formation is considered.

Tuning the basicity of cyano-containing ionic liquids to improve SO2 capture through cyano-sulfur interactions.

A new approach has been developed to improve SO2 sorption by cyano-containing ionic liquids (ILs) through tuning the basicity of ILs and cyano-sulfur interaction. Several kinds of cyano-containing ILs with different basicity were designed, prepared, and used for SO2 capture. The interaction between these cyano-containing ILs and SO2 was investigated by FTIR and NMR methods. Spectroscopic investigations and quantum chemical calculations showed that dramatic effects on SO2 capacity originate from the basicity of the ILs and enhanced cyano-sulfur interaction. Furthermore, the captured SO2 was easy to release by heating or bubbling N2 through the ILs. This efficient and reversible process, achieved by tuning the basicity of ILs, is an excellent alternative to current technologies for SO2 capture.

Highly efficient and reversible SO2 capture by halogenated carboxylate ionic liquids

Several halogenated carboxylate ionic liquids were developed for SO2 capture. Both enhanced capacity, improved desorption, and reversibility of ionic liquids can be achieved via adding halogen sulfur interaction between halogen on the anion and SO2.

Influence of phosphorus and sulphur levels on nodulation, growth parameters and yield of soybean (Glycine max L.) grown on Vertisol

A field experiments were conducted for two consecutive years during 2009-10 and 2010-11to study the effect of phosphorus and sulphur levels on soybean (Glycine max L.) at Research Farm, Department of Soil Science and Agril. Chemistry, Vasantrao Naik Marathwada Krishi Vidyapeeth, Parbhani (M.S.) on Vertisol (Typic Hapluster) deficient in phosphorus and sulphur. The treatments consisted of four levels of sulphur (S0, S20, S40 and S60 kg ha-1) and four levels of phosphorus (P0, P30, P60 and P90 kg P2O5 ha-1) applied through elemental sulphur and DAP, respectively. Results revealed that due to increase in the phosphorus and sulphur levels, there was effective improvement in nodulation, fresh weight of nodules plant-1 and growth parameters viz., plant height, leaf area, root length, root dry weight plant-1 and number of pods plant-1 at various growth stages of soybean. The yield i.e. grain, straw and total biological yield of soybean increased significantly with increasing levels of both phosphorus and sulphur. Further, synergistic effect of phosphorus and sulphur interactions on straw and total biological yield was highest at 90 kg P2O5 + 60 kg S ha-1 followed by 90 kg P2O5 + 40 kg S ha-1, 90 kg P2O5 + 20 kg S ha-1 and 60 kg P2O5 + 60 kg S ha-1 in straw yield and 90 kg P2O5 ha-1 with 60 or 40 kg S ha-1 produced significantly higher yield over S application with 30 and 0 kg P2O5 ha-1 in total biological yield.

Trithiacrown palladium(II) complexes with cyclometallating ligands: Isomer effects, intramolecular palladium–sulfur interactions, and reversible PdII/III and PdIII/IV oxidations

We report the synthesis and characterization of a series of cyclometallated complexes of Pd(II) incorporating the fluxional trithiacrown ligand 1,4,7-trithiacyclononane ([9]aneS3). Reaction of palladium(II) acetate with 2,3′-thienylpyridine (2,3′thpy), 2,2′-thienylpyridine (2,3′thpy), 2-benzothienylpyridine (btp), and 2-phenylbenzothiazole (pbt) resulted in the formation of di-μ-acetate bridged dimers of the form [Pd(CˆN)(μ-O2CCH3)]2 (CˆN = deprotonated cyclometallated ligand). The NMR spectra of these dimers indicate the presence of both anti and syn isomers in each cyclometallated ligand analog. X-ray crystal structures of anti-[Pd(CˆN)(μ-O2CCH3)]2 (CˆN = 2,3′thpy and btp) show intermolecular π-stacking. Reaction of [Pd(CˆN)(μ-O2CCH3)]2 with [9]aneS3 followed by metathesis with NH4PF6 yields [Pd(CˆN)([9]aneS3)](PF6). 1H and 13C NMR studies demonstrate that the coordinated [9]aneS3 ligand is fluxional on the NMR timescale at ambient temperature. X-ray crystallographic studies reveal the elongated square pyramidal structure of these [Pd(CˆN)([9]aneS3)](PF6) complexes which possess two typical equatorial Pd–S bonds and an additional Pd⋯S interaction shorter than van der Waals radii sum. Intermolecular π-stacking features of these [Pd(CˆN)([9]aneS3)](PF6) structures are discussed in light of previously described common motifs found in related structures. NMR and crystallographic evidence are presented that indicate the 2,3′thpy ligand coordinates to Pd(II) in both κC2 and κC3 modes, forming linkage isomers. Electrochemical studies of the [Pd(CˆN)([9]aneS3)](PF6) complexes reveal two reversible one-electron oxidations, an exceptional behavior. These oxidations are assigned as metal-based PdII/III and PdIII/IV processes. The complex cis-[Pd(2,3′thpy)2], synthesized using a room temperature double C–H bond activation procedure, was characterized by 1H NMR and X-ray crystallography.

Sulfur Interaction with Cu(100) and Cu(111) Surfaces: A Photoemission Study

Results of a high-resolution synchrotron photoemission study of sulfur adsorption on Cu(100) and Cu(111) surfaces are reported. Sulfur adsorption was performed by immersion of pristine samples into aqueous Na2S, which provokes strong sulfidation of copper. Annealing leads to partial elimination of S and progressive formation of well-ordered surface sulfur phases followed here by LEED. This translates into sizable Cu 2p core level binding energy (CLBE) shifts as well as changes in the S 2p binding energies. For Cu(111) we see evolution at the higher temperature to the (√7 × √7)R19.1° phase as identified by LEED, with a S 2p3/2 binding energy of 161.45 eV. An intermediate phase with an S 2p3/2, binding energy of 161.15 eV appears at lower temperatures. For Cu(100) at 300 °C we see the appearance of the known 0.47 ML S coverage (√17 × √17)R14° structure, with S 2p3/2 CLBE of 161.15, 161.62, and 162.10 eV. At higher temperatures some S atom loss occurs, and we observe a p(2 × 2)-S phase, with S 2p3/2 CLBE of 161.05 eV and a smaller component at 164.45 eV that could correspond to local c(4 × 2) domain boundaries as identified in earlier studies. The core level binding energies of Cu 2p are reported along with valence band characteristics.

How reliable is the ReaxFF potential for describing the structure of alkanethiols on gold? A molecular dynamics study

The structures of self-assembled monolayers (SAMs) of short (methyl) and long (hexyl) chain alkyl thiols on the clean gold(111) surface were modeled using for the Au – S interactions either the reactive ReaxFF potential or the well-known nonreactive Morse potential, while for the Au – Au interactions either the ReaxFF potential or an embedded-atom method (EAM). Analysis of the molecular dynamics (MD) trajectories of possible SAM structures suggests that disordering of interfacial Au atoms is definitely driven by the gold–sulphur interactions. Our MD results reveal a novel structure where two methanethiol molecules are bound to a gold adatom that has been lifted from the surface at 300 K, and the same kind of RS– Au –SR motif was also observed for hexanethiol at 600 K but not at 300 K. What is more, the above motif is only observed for the reactive ReaxFF potential. Moreover, these results are in clear agreement with recent experiments and more costly first principles-based MD simulations. These findings strongly support the use of reactive potentials such as ReaxFF for gathering an accurate description of Au – S interactions in inexpensive classical MD simulations.

Use of H2S to Probe the Active Sites in FeNC Catalysts for the Oxygen Reduction Reaction (ORR) in Acidic Media

H2S has been used as a probe molecule both in an “in situ” poisoning experiment and in intermediate-temperature heat-treatment steps during and after the preparation of FeNC catalysts in an attempt to analyze its effect on their ORR activity. The heat treatments were employed either on the ball-milled precursor of FeNC or after the Ar-NH3 high temperature heat treatments. ORR activity of the H2S-treated catalysts was seen to be significantly lower than the sulfur-free catalysts, whether the sulfur exposure was during a half-cell testing, or as an intermediate-temperature exposure to H2S. The incorporation of sulfur species and interaction of Fe with sulfur were confirmed by characterization using XPS, EXAFS, TPO, and TPD. This study provides crucial evidence regarding differences in active sites in FeNC versus nitrogen-containing carbon nanostructured (CNx) catalysts.

Organic Semiconductors: Rational Design of Organic Semiconductors for Texture Control and Self‐Patterning on Halogenated Surfaces (Adv. Funct. Mater. 32/2014)

Halogen–halogen and halogen–sulphur interactions at the interface between a semiconductor and self-assembled monolayer-treated contacts can mediate film crystallization in organic thinfilm transistors. On page 5052, A. Amassian, O. D. Jurchescu, and co-workers explain how highly ordered films form when such interactions are allowed by the structure and orientation of the consituent molecules during the heterogenous nucleation at the solution–solid interface.

Tailoring interactions of carbon and sulfur in Li–S battery cathodes: significant effects of carbon–heteroatom bonds

In this study, effects of carbon–heteroatom bonds on sulfur cathodes were investigated. A series of carbon black substrates were prepared using various treatments to introduce nitrogen or oxygen surface species. Our results indicated that nitrogen-doped carbon black significantly improved the electrochemical performance of sulfur cathode materials. Synchrotron-based XPS revealed that the defect sites of nitrogen-doped carbon are favorable for the discharge product deposition, leading to a high utilization and reversibility of sulfur cathodes. Our studies also found that the introduction of oxygen functional groups results in deteriorated performance of Li–sulfur batteries due to the reduced conductivity and unwanted side reactions occurring between sulfur and surface oxygen species.

Intramolecularly Sulfur-Stabilized Silicon Cations as Lewis Acid Catalysts

The synthesis and spectroscopic characterization of previously unprecedented sulfur-stabilized silicon cations are reported. Several 1,3-dithiolan-2-yl- and 1,3-dithian-2-yl-substituted silanes were prepared and successfully transformed into the corresponding silicon cations by hydride abstraction. The silicon–sulfur interaction creates three consecutive stereocenters at three different elements. It is remarkable that the present stereocenter at the silicon atom determines the stereochemical outcome at the formerly prochiral sulfur and carbon atoms with excellent diastereoselectivity. All sulfur-stabilized silicon cations are shown to be potent catalysts in a challenging Diels–Alder reaction. Moreover, structurally related oxazoline-stabilized silicon cations were generated and characterized but found to be unreactive.

INFLUENCE OF SULPHUR AND CARBOFURAN NEMATICIDE ON ROOT-KNOT NEMATODE AND THE PERFORMANCE OF SOME SUGAR BEET VARIETIES IN SANDY SOIL

Two field trials were carried out in Nubaryia region, El BeheiraGovernorate, Egypt throughout two successive seasons of 2012/2013 and2013/2014 to examine the response of five multigerm varieties of sugarbeet (Beta vulgaris, sacchrifera L.) as affected by agricultural sulphur(100 kg/fed.), and nematicide, furan (carbofuran10% G) at 13 kg/fed onroot knot nematode, Meloidogyne incognita under naturally infected withit. A split-split plots design was used, where sulphur treatments in mainplots, the nematicide, in the sub-plots, and sugar beet varieties were sownin the sub-sub- plots. Results obtained cleared that number of galls/ plantsignificantly affected by sulphur treatments, this finding was true in bothgrowing seasons at the two studied age i.e. 3-momth or 6- month.Application of 100 kg sulphur reduced the values of galls from 15.6 to 9.0in the 1st age corresponding 38 to 25 in the 2nd age. The percent ofreduction amounted by 73.33% and 52.0% at age 3 and 6 monthsrespectively. Once more, the differences between sulphur treatments didnot reach the level of significant in respect to their effect on galls numberin the 2nd seasons of both ages. Concerning carbofuran (C) influence, theresults showed that the used nematicide compound significantly reducedthe percent values of gall’s number, the amount of reduction reached to140 and 152 % in the 1st and 2nd seasons at age of 3- month corresponding172 and 226.4 % in 6- month age in the 1st and 2nd season respectively.This result may be indicating to the high specificity against nematode.Regarding the different combination between the studied factors, it couldbe noted that the 1st and 2nd order interaction were significantly effected onthe values of gall’s number/ root in both seasons whether at 3-momth or 6-month ages. Once more by the end of growing season (six months), thevalues of egg masses significantly affected by the individual studiedfactors. Application of 100 kg sulphur significantly reduced the values ofeggmasses/root. As for, the influence of carbofuran nematicide on eggmasses, the available data appeared highly response to carbofuran inrespect to its effect on egg masses in the two growing seasons, usingcarbofuran et a reduction in this trait amounted by 113.33 and 137.5% inthe 1st and 2nd seasons respectively. Belong to varietal difference in respectto egg masses, the collected results showed sugar beet variety Gloriserecorded the lowest value of this trait in both seasons. This finding may beassured the gen make up role in its influence on varieties with respect to their resistance against nematode infection. The most effect interaction wasthat between sugar beet varieties and each of sulphar treatment andnematicide. Sugar beet root fresh weight, root diameter and sugar yield/fedincreased significantly at the studied rates of nematicide and sulphur in the1st and 2nd seasons. Root yield had the same trend in the 2nd season only.Sucrose% and sugar extractable% significantly increased at the rates ofnematicide and sulphur treatments in both seasons, respectively. Glorisevariety cleared the significant superiority over all the other tested ones insucrose%, without significant variance with lilly variety. The interactionbetween the used rates of sulphur and carbofuran nematicide had the sameeffect on root diameter in both seasons. Sulphur treatment at developedroot quality and reduced the impurity of juice of sugar beet and increasedroot growth as well as carbofuran nematicide did. Alpha amino nitrogen insugar beet roots was significantly influenced by sulphur and carbofurannematicide interaction in both seasons. Potassium, sucrose and extractablesugar percentages and percentage extractability of root juice weresignificantly recorded impacts by the interaction between varieties andsulphur levels in both seasons.