Background Sudden changes in masticatory loads and occlusal conditions contribute to temporomandibular disorders. Clockwise (CW) or counterclockwise (CCW) rotation of the occlusal plane is one of the factors that alter the direction of the occlusal forces transmitted to the temporomandibular joint structures. Finite element analysis was used to identify possible regions of high stress in the temporomandibular joint. Materials and Methods A computer-aided design model of a symmetrical edentulous maxillomandibular bony complex with a temporomandibular joint was manually generated using Rhinoceros 4.0 freeform modeling software. Three-dimensional discrete mesh generation was performed using VRMesh Studio. The reference occlusal plane angle was accepted as 8° in the sagittal plane, and by modifying 4° in the CW and CCW directions, CW and CCW models were obtained, respectively. The present study aimed to evaluate the changes in stress distribution in the condylar cartilage and temporomandibular disc using the von Mises and maximum-minimum principal stress evaluations of three different occlusal plane inclinations. The null hypothesis of this three-dimensional finite element analysis was that “occlusal plane inclination does not change the stress distribution on the temporomandibular joint structures.” Results The compressive stress on the condyle increased with CW rotation of the occlusal plane. The von Mises equivalent stress of the temporomandibular disc shifted to the medial, posterior, and superior directions after CW and CCW rotations of the occlusal plane. The CW rotation of the occlusal plane increased the von Mises equivalent.