Suction-assisted installation is one of the special features that distinguishes the suction caisson from other offshore foundations. Suction control during installation can be challenging, as it involves highly coupled processes between seepage flow and seabed soil deformations, including excessive soil deformation and plug formation under strong seepage actions that lead to early termination of the installation, as well as a seepage flow-induced reduction in caisson penetration resistance. However, existing methods for evaluating suction caisson installation are primarily based on pure seepage analysis while disregarding the above-coupled processes. This paper proposes an approach to evaluate suction caisson installation in sand by explicitly accounting for seepage-deformation coupling. For this purpose, pore pressure-deformation coupled finite element analyses are performed to investigate soil failure mechanism and evolving caisson penetration resistance subjected to suction. These analyses result in novel rules for assessing critical suction upon the rapid growth of soil deformation and describing the degradation of caisson penetration resistance. The latter two propositions lead to a new calculation method for determining the required suction for caisson installation. The performance of the calculation method is evaluated against field tests and centrifuge tests to illustrate the usefulness of considering coupled soil deformation-seepage process in designing caisson installation.