Successive Sessions Research Articles

An automated on-line clinical mastitis detection system using measurement of electrical parameters and milk production efficiency

This study aims to assess a novel method for automatic on-line detection of clinical mastitis in an automatic milking system using the measurement of electrical parameters, data of milk production efficiency and neural network from the novel mastitis detection sensor. The sensors were used to measure following 9 parameters: the quarter-level milk yield (MY; kg), average electrical conductivity in milking session (AEC; mS/cm), pH of milk (pH), temperatures of milk (TP; °C), milk production efficiency (MPE; kg/h) between successive milking sessions, milking time(MT; min), Milking efficiency (ME; kg/min), Milk production time(MPT; kg/h), cow number. The 9 measurements were inputted into a neural network to calculate the mastitis detection index. The network was trained with 44 healthy and 6 clinical mastitic cows. 42 of 44 healthy and 5 of 6 mastitic cows were classified correctly after training. The trained neural network predicted 164 of 176 healthy quarters correctly in different evaluation data sets. These results were better than the results obtained with the model usually used on the farm.

Categorical Auditory Working Memory in Crows.

SummaryThe ability to group sensory data into behaviorally meaningful classes and to maintain these perceptual categories active in working memory is key to intelligent behavior. Here, we show that carrion crows, highly vocal and cognitively advanced corvid songbirds, possess categorical auditory working memory. The crows were trained in a delayed match-to-category task that required them to flexibly match remembered sounds based on the upward or downward shift of the sounds' frequency modulation. After training, the crows instantaneously classified novel sounds into the correct auditory categories. The crows showed sharp category boundaries as a function of the relative frequency interval of the modulation. In addition, the crows generalized frequency-modulated sounds within a category and correctly classified novel sounds kept in working memory irrespective of other acoustic features of the sound. This suggests that crows can form and actively memorize auditory perceptual categories in the service of cognitive control of their goal-directed behaviors.

The effect of a stress ball on stress, vital signs and patient comfort in hemodialysis patients: A randomized controlled trial

ObjectiveIn this study, an investigation was made of the effect of the use of a stress ball, a method of distraction–attracting the attention elsewhere – on stress, vital signs andcomfort levels in hemodialysis patients. MethodsThis randomized, controlled experimental study, between July 2019 and September 2019 was carried out in a dialysis unit in the inner regions of Turkey. The study was conducted with 45 patients (23 experiments, 22 controls) who were receiving hemodialysis treatment. The experimental group were asked to squeeze a stress ball for approximately 10–15 min throughout eight successive dialysis sessions. The data were obtained with an Individual Description Form, the Distress Thermometer and the Hemodialysis Comfort Scale. ResultsAt the end of the study, no significant difference was found in the vital signs and comfort levels of the experimental and control groups (p > 0.05). However, while the stress score of the experimental group decreased significantly, the stress score of the control groups increased (p < 0.05). ConclusionThis study shows that although the use of the stress ball did not affect vital signs and comfort in hemodialysis patients, it had a positive effect on stress.

An experience-based contrast effect when relying on a decision aid

The present study investigates experience-based contrast effect as a factor that affects users’ decision to rely on decision support systems or not. Two types of experience-based contrast effects were evaluated: “hands-on” and “hard first, simple second.” In the first study, testing “hands-on” contrast, we examined its effect by giving users experience with a task before introducing them to a hard-to-use decision aid to carry out the same task. In the second study, examining “hard first, simple second” contrast, the effect was evaluated by introducing users first to a hard-to-use decision aid and thereafter to a simple decision aid. In both studies, participants took part in two successive sessions in a simulation-based supply chain game. Results demonstrated that both types of contrasts reduced participants’ reliance on the decision aids. Hence, when encouraging users to rely on a decision aid, one should consider the experience-based contrast effects and use them carefully. The implications from this work can contribute to our understanding of the role of experience-based contrast effect when relying on a decision aid.

Collaborative Facilitation and Collaborative Inhibition in Virtual Environments

Worldwide, organizations and small and medium-sized enterprises have already disruptively changed in many ways their physiological inner mechanisms, because of information and communication technologies (ICT) revolution. Nevertheless, the still ongoing COVID-19 worldwide emergency definitely promoted a wide adoption of teleworking modalities for many people around the world, making it more relevant than before to understand the real impact of virtual environments (VEs) on teamwork dynamics. From a psychological point of view, a critical question about teleworking modalities is how the social and cognitive dynamics of collaborative facilitation and collaborative inhibition would affect teamwork within VEs. This study analyzed the impact of a virtual environment (VE) on the recall of individuals and members of nominal and collaborative groups. The research assessed costs and benefits for collaborative retrieval by testing the effect of experimental conditions, stimulus materials, group size, experimental conditions order, anxiety state, personality traits, gender group composition and social interactions. A total of 144 participants were engaged in a virtual Deese-Roediger-McDermott (DRM) classical paradigm, which involved remembering word lists across two successive sessions, in one of four protocols: I-individual/nominal, I I -nominal/individual, I I I -nominal/collaborative, I V -collaborative/nominal. Results suggested, in general, a reduced collaborative inhibition effect in the collaborative condition than the nominal and individual condition. A combined effect between experimental condition and difficulty of the task appears to explain the presence of collaborative inhibition or facilitation. Nominal groups appeared to enhance the collaborative groups’ performance when virtual nominal groups come before collaborative groups. Variables such as personality traits, gender and social interactions may have a contribution to collaborative retrieval. In conclusion, this study indicated how VEs could maintain those peculiar social dynamics characterizing the participants’ engagement in a task, both working together and individually, and could affect their intrinsic motivation as well as performances. These results could be exploited in order to design brand new and evidenced-based practices, to improve teleworking procedures and workers well-being, as well as teleworking teamwork effectiveness.

Effect of heat-producing needling technique on the local skin temperature: a clinical study

ObjectiveThis clinical study was performed to examine the influence of heat-producing acupuncture (HPA) treatment on the local skin temperature of Zúsānlĭ (足三里ST36) acupoint in healthy participants. Methods30 healthy participants received four successive sessions of heat-producing acupuncture (HPA), non-acupoint HPA (NAHPA), normal stable acupuncture (Norm) and non-invasive sham acupuncture (Sham) on the ST36 acupoint in random order. Within each treatment session, the local skin temperature of ST36 acupoint and basal body temperature of each participant were measured at 1 min before needle insertion (T1B), just after needle insertion and manipulation (T0), 5 min after needle insertion (T5) and 5 min after needle removal (T5A). Visual Analogue Scale (VAS) scores of the participants’ perceived needling and heat sensation felt during the acupuncture treatment period (T0-T5) were also recorded on a scale of 1 to 10. ResultsIntra-session group statistical analyses of the different time points in the HPA treatment session group demonstrates that ST36 local skin temperature remained relatively stable between T1B and T0, increased significantly between T0 and T5 and decreased significantly between T5 and T5A. For inter-session group statistical analysis of all treatment session groups, the increase in local skin temperature of ST36 acupoint between T0 and T5 in the HPA treatment session group was significantly higher than those of the NAHPA treatment session group (P < 0.01), Norm treatment session group (P < 0.01) and Sham treatment session group (P < 0.01). The decrease in local skin temperature of ST36 acupoint between T5 and T5A in the HPA treatment session group was also significantly more than those of NAHPA treatment session group (P < 0.05), Norm treatment session group (P < 0.01) and Sham treatment session group (P < 0.001). ConclusionOur study provides evidence that HPA treatment performed significantly better than the other three treatments in elevating the local skin temperature of ST36 acupoint temporarily. Our results also align with those of many previous clinical studies on HPA and related acupuncture manipulations.

Applying the Silent Way in Teaching Japanese Language to University Students in Taiwan

The present study investigated the feasibility of applying the Silent Way in teaching Japanese to Taiwanese university students. A total of 168 (96 female and 72 male) students in a university in central Taiwan were the subjects of this study. They were studying Japanese as a general course, and were grouped in five classes ranging from freshmen to juniors. Some basic principles and techniques of the Silent Way were adopted in teaching them some vocabulary and 50 Japanese Hiragana sounds during six successive sessions in three weeks. Each administration took about 20 minutes embedded in the normal class time. A 25-item Hiragana sounds oral test was used as the pre-test and post-test in order to examine the effects of applying this method. Using a paired sample T-test (α ≤.05) significant difference between students’ knowledge of the Japanese sounds before and after the experiment was observed. However, comparing female and male students’ gained scores via applying a Mann Whitney U-test, no significant difference was observed. Thus, this study shows that the Silent Way can be used in teaching Japanese sounds and vocabulary, and that the effects for both females and males seem to be the same.

SAT-240 INTER-DIALYTIC WEIGHT GAIN IN HEMODIALYSIS PATIENTS - EPIDEMIOLOGY AND EVALUATION OF THE CLINICAL OUTCOMES

Inter-dialytic weight gain (IDWG) has been linked to various complications in hemodialysis (HD) patients, especially cardiovascular (CV) complications. High ultrafiltration (UF) rate in relation to dialysis time has also a similar impact in various studies. Furthermore, high IDWG has been associated with all cause and CV mortality. The IDWG is also influenced by the nutritional status of HD patients. We investigated the trends of IDWG in patients on regular HD aiming to examine: (1) trends of IDWG among patients in relation to different variables and comorbidities e.g. age, hypertension, diabetes, CV disease...etc.; (2) associations of high IDWG with frequency of hospitalization due to systemic volume overload and the need for extra dialysis sessions, and (3) the impact of high IDWG on the frequency of intra-dialytic hypotension (IDH). One hundred and twenty maintenance HD patients were enrolled in this study. All patients had been receiving HD for at least 3 months, on a 4 hour, thrice weekly basis. The data collected included; age, gender, duration on HD (in months), pre- and post-HD body weights (on 3 successive sessions), pre- and post-HD blood pressure (BP) measurements (on 3 successive sessions), the type of vascular access and the average blood flow rate, dialysis efficiency (based on average Kt/V), and the presence or absence of residual kidney function. The presence of various comorbidities has been recorded including; diabetes, hypertension, coronary artery and peripheral vascular diseases, heart failure, cerebrovascular disease, and other disorders. The estimated IDWG was calculated based on the average between pre- and post- dialysis weights that were recorded on 3 consecutive dialysis sessions. The estimated IDWG was expressed in kilograms and as a percentage of the patients’ dry weight. We considered an estimated average IDWG of 4% as a cutoff value between low and high IDWG. We defined IDH as the drop of systolic blood pressure of 20 mmHg or more during HD compared to the pre-dialysis blood pressure and/or a systolic blood pressure that is less than 90 mmHg. We have recorded that 50.0% of those younger than 55 years had IDWG ≥ 4%. On the other hand, only 31.7% of those aged 55 years or more had IDWG ≥ 4% (p=0.041). There was no significant gender difference regarding IDWG. Among those who had IDWG ≥ 4%, 81% of these patients had at least one hospital admission due to volume overload or the need for extra HD session(s). On the other hand, only 19% of those having IDWG < 4% had been admitted or got extra HD sessions (p<0.001). Of those who were admitted (over 12 months) due to volume overload; 74.1 % had IDWG ≥ 4%, while 25.9% had IDWG < 4% (p< 0.001). Regarding IDH, 87% of patients having IDWG ≥ 4% had at least one episode of IDH/week. On the other hand, only 22.5% of those with IDWG < 4% had one episode of IDH/week (p<0.001). When analyzing those who had at least one IDH episode/week; 72.9% of them had IDWG ≥ 4%, while only 27.1% had IDWG < 4% (p<0.001).View Large Image Figure ViewerDownload Hi-res image Download (PPT)View Large Image Figure ViewerDownload Hi-res image Download (PPT) In HD patients, the frequency of hospital admission due to volume overload and the need for extra HD sessions is strongly related to the amount of IDWG (> 4% in our patients). The same stands for the frequency of IDH. Thus a control of IDWG in HD patient is of great importance, keeping in mind the importance the nutritional status of HD patients that may also impact IDWG.

Grazing intensity negatively affects the maintenance of Gentiana pneumonanthe and the survival of Phengaris alcon egg-laying

Phengaris alcon is an endangered butterfly that is subject to several conservation programs in Europe. Our study aims at evaluating how grazing pressure by domestic animals affects the maintenance of Gentiana pneumonanthe stems, larval plant host of Phengaris alcon and the survival of Phengaris alcon's eggs. We selected 304 stems of G. pneumonanthe (including 125 with P. alcon eggs) that were distributed over 4 ungrazed plots and 18 plots grazed by cattle or horses, for which we collected a grazing pressure index (Livestock Units days grazed ha−1). We monitored each stem over seven sampling sessions at 10 days intervals during the summer (from 02 July to 12 September 2018). We demonstrated that the G. pneumonanthe stems browsing probability was two times higher in the grazed plots than in the ungrazed plots. The number of eggs sharply decreased in the grazed plots, whereas it remained constant in the ungrazed plots during successive sampling sessions. Grazing, even at low intensity (10 LU days grazed ha−1), induced defoliation of G. pneumonanthe stems. The probability of the maintenance of G. pneumonanthe stems and the probability of survival of P. alcon eggs is close to zero above 20 LU days grazed ha−1. In order to protect the P. alcon population, we recommend extensive and early grazing (before mid-July) before the growth of G. pneumonanthe stems, or late grazing (after early September) avoiding the development period of G. pneumonanthe, the oviposition period and the early caterpillar development of P. alcon. Alternatively, we suggest the establishment of temporary exclosures on high densities areas of G. pneumonanthe between mid-July to early September.

Escritura colaborativa e individual: Efectos en el desarrollo de la precisión y fluidez

The present study investigates the differential effects of collaborative vs. individual writing approaches on the development of fluency and accuracy among male and female EFL learners. The study is unprecedented in terms of investigating the effect of these two approaches on fluency and accuracy development in the long-run through a delayed posttest. Additionally, the study examines the development of fluency and accuracy over seven successive sessions longitudinally. The written outputs, produced by the participants, were scored for fluency and accuracy according to the method applied by Wigglesworth and Storch (2009). The Data, analyzed through MANCOVA and ANOVA analyses, revealed that collaborative writing led to more fluent texts for both males and females in the short and the long run. Also, the collaboratively written compositions were more accurate in comparison to those written individually for males and females in the short and long run.

Prevalence of renewal of problem behavior during context changes.

Renewal is defined as the reemergence of a previously eliminated behavior following a context change. Determining the prevalence of this effect in clinical practice would allow clinicians to better anticipate the reemergence of problem behavior, such as when a patient is discharged from a treatment facility to return to their home. The current consecutive, case-series analysis determined the prevalence and magnitude of renewal when implementing behavioral treatments for problem behavior. Across 182 context changes, renewal was observed 77 times (42.3%). In the first session following the context change, problem behavior rates increased by a factor of 3 and then decreased across successive sessions. These results indicated that renewal effects may be common, but are also transient and return to rates observed before context changes.

Understanding Controller-Pilot Interaction Dynamics in The Context of Air Traffic Control

LiteratureNew capabilities to modernize the U.S. National Airspace System (NAS) include support of real-time information streams derived from many data sources across the NAS. As an emergent proper...

Development of a model of the service system of batch arrivals in the passengers flow of public transport

A mathematical model of the queuing system for the passenger flow of urban public transport is proposed. The resulting model differs from canonical models of queuing theory by taking into account the fundamental features of real systems. Firstly, the service process is divided into different successive service sessions. Secondly, arrival and departures are batch. Thirdly, the arrival rates vary in different service sessions. Fourthly, the laws of distribution of the number of jobs in batch arrivals for different sessions are different. Fifth, the laws of distribution of the number of batch arrivals and departures are also different.A criterion of efficiency of the service system is developed. The criterion is based on the calculation of the probability distribution of the service system states at the input and similar distribution at the output. These distributions are determined independently for each service session, into which the entire service cycle is divided. The numerical value of the criterion is set by the ratio of the average number of service rejections to the average number of jobs in the batch arrival for the entire service cycle. It can be used to assess the efficiency of the service system at any selected time interval during the day, because the value of the proposed criterion depends on the length of the interval between sessions, determined by the number of vehicles on the route.The resulting models adequately reflect the functioning of the system, which makes it possible to predict many different situations and evaluate the consequences of proposed solutions. Thus, it becomes possible to predict the provision of the population with public transport and determine quantitative values of efficiency of the urban public transport system

The Impact of Situational Test Anxiety on Retest Effects in Cognitive Ability Testing: A Structural Equation Modeling Approach.

When a cognitive ability is assessed repeatedly, test scores and ability estimates are often observed to increase across test sessions. This phenomenon is known as the retest (or practice) effect. One explanation for retest effects is that situational test anxiety interferes with a testee’s performance during earlier test sessions, thereby creating systematic measurement bias on the test items (interference hypothesis). Yet, the influence of anxiety diminishes with test repetitions. This explanation is controversial, since the presence of measurement bias during earlier measurement occasions cannot always be confirmed. It is argued that people from the lower end of the ability spectrum become aware of their deficits in test situations and therefore report higher anxiety (deficit hypothesis). In 2014, a structural equation model was proposed that specifically allows the comparison of these two hypotheses with regard to explanatory power for the negative anxiety–ability correlation found in cross-sectional assessments. We extended this model for usage in longitudinal studies to investigate the impact of test anxiety on test performance and on retest effects. A latent neighbor-change growth curve was implemented into the model that enables an estimation of retest effects between all pairs of successive test sessions. Systematic restrictions on model parameters allow testing the hypothetical reduction in anxiety interference over the test sessions, which can be compared to retest effect sizes. In an empirical study with seven measurement occasions, we found that a substantial reduction in interference upon the second test session was associated with the largest retest effect in a figural matrices test, which served as a proxy measure for general intelligence. However, smaller retest effects occurred up to the fourth test administration, whereas evidence for anxiety-induced measurement bias was only produced for the first two test sessions. Anxiety and ability were not negatively correlated at any time when the interference effects were controlled for. Implications, limitations, and suggestions for future research are discussed.

Zmiany aktywności fal mózgowych pod wpływem treningu neurofeedback u zawodników judo

Cel badań. Celem niniejszego badania była analiza dynamiki zmienności wartości fal Theta i Beta w grupach eksperymentalnej i kontrolnej po kolejnych sesjach biofeedback oraz określenie optymalnej liczby jednostek treningowych wystarczających do osiągniecia celu badania, jakim była poprawa szybkości reakcji w badanej grupie zawodników judo.&#x0D; Metodologia. W badaniu wzięło udział 12 mężczyzn – zawodników kadry narodowej Polskiego Związku Judo. Zawodnicy uczestniczyli w dwóch cyklach treningowych, każdy po 15 sesji. Czas trwania treningu wynosił 4 minuty. W pierwszej sesji treningi odbywały się co drugi dzień. Druga seria badań, która odbyła się po czterotygodniowej przerwie, charakteryzowała się tym samym czasem trwania, jednak treningi odbywały się codziennie. Komputerowy test szybkości reakcji oraz wybrane próby systemu wiedeńskiego zostały wykonane przed oraz po zakończeniu każdego cyklu treningowego. Zawodnicy wykonywali trening na podstawie protokołu beta1/theta przy użyciu oprogramowania Biograf Infiniti 6.0 oraz 5 – kanałowego urządzenia dekodującego ProComp5 z sensorem EEG.&#x0D; Wyniki. Szczegółowa analiza wyników pokazuje, że zastosowanie treningu biofeedback, który przyczynił się do poprawy szybkości reakcji, znacząco wpływa na dynamikę aktywności fal mózgowych.&#x0D; Wnioski. Trening neurofeedback u zawodników judo może prowadzić do polepszenia wyników związanych z poprawą szybkości reakcji. Konieczne są jednak dalsze badania na szerszej grupie zawodników.&#x0D; Słowa kluczowe: Neurofeedback, judo, biofeedback, EEG.

Improvement of asthma control after laser acupuncture and its impact on exhaled 8-isoprostane as an oxidative biomarker in chronic bronchial asthma.

to assess efficacy of laser acupuncture in improving asthma symptoms and underlying oxidative stress through monitoring exhaled 8-isoprostane. 48 asthmatic (case group) received successive low level laser acupuncture sessions to stimulate acupoints for chronic asthma and 24 asthmatics received deactivated laser acupuncture sessions (control group). Asthma symptoms, asthma control questionnaire, concentration of 8-Isoprostane in exhaled breath condensate and airway resistance were assessed before and after laser acupuncture therapy. After the completion of the course of laser acupuncture therapy, we observed significant improvement of asthma symptoms. Asthma control questionnaire improved from 9.7 ± 3.3 to 21.8 ± 3.6 (p 0.001). EBC 8-Isoprostane dropped from 14.7 ± 5.4 to 8.1 ± 5.0 (p 0.001). The airway resistance at R5 and R20 significantly decreased from 116.6 ± 25.8 & 124.5 ± 31.2 to 101.5 ± 25.6 &110.9 ± 29.9 respectively (p 0.001). Control patients who received sham acupuncture therapy did not show such improvement. Laser acupuncture is an effective modality in treating bronchial asthma as evidenced by improved symptoms, airway resistance, and oxidative biomarkers.

Antimicrobial photodynamic therapy reduces adhesion capacity and biofilm formation of Candida albicans from induced oral candidiasis in mice.

Antimicrobial photodynamic therapy (aPDT) has been considered an alternative therapeutic modality for the treatment of Candida infections. However, most studies are focused mainly on microorganism's inactivation efficiency. Here, we evaluated the efficacy of aPDT mediated by chloro-aluminum phthalocyanine encapsulated in cationic nanoemulsions (ClAlP-NE) to treat oral candidiasis in vivo and its effect on the adhesion and biofilm formation of Candida albicans. For this, mice were immunosuppressed and inoculated with C. albicans to produce oral candidiasis. aPDT and Nystatin were applied for 5 successive sessions. Next, the microbiological evaluation was determined (CFU/ml) and the analyses of virulence factors (adhesion capacity and biofilm formation) were performed. Data were analyzed by Two-way ANOVA (α = 0.05). aPDT was as effective as Nystatin reducing 1.4 and 2.0 log10 of the cell viability (p ≤ 0.0001), respectively. Both treatments reduced the adhesion capacity and biofilm formation of C. albicans (p ≤ 0.0001) CONCLUSION: : ClAlP-NE-mediated aPDT was effective in reducing the virulence factors of C. albicans and also to treat induced oral candidiasis in mice.

The Effects of Peer Support on Depression, Anxiety, and Stress Among Patients Receiving Hemodialysis

Background: Depression, anxiety, and stress are the most prevalent psychological disorders among patients with chronic renal failure. These disorders increase mortality rate, impair immune function, reduce treatment adherence and quality of life, and heighten the risks of malnutrition, infection, and cardiovascular diseases. One potentially effective strategy for the management of psychological disorders is peer education; however, its effects on patients receiving hemodialysis are still unknown. Objectives: This study was conducted to investigate the effects of peer education on depression, anxiety, and stress among hemodialysis patients. Methods: This was a quasi-experimental study. Patients were randomly recruited and allocated in intervention and control groups. In the intervention group, patients were provided with two 120-minute peer education sessions per week for eight successive weeks-sixteen sessions in total. Patients in the control group solely received routine care services, which included no education by peers. Data were collected before and immediately after the intervention via the 42-item Depression Anxiety Stress Scale. Results: Before the intervention, the groups did not significantly differ from each other, respecting the mean scores of depression, anxiety, and stress (P > 0.05). After the intervention, significant decreases in the mean scores of depression, anxiety, and stress were observed in the intervention group (P 0.05). Consequently, posttest mean scores in the intervention group were significantly lower than the control group (P < 0.05). Conclusions: Peer education is effective in significantly alleviating hemodialysis patients’ depression, anxiety, and stress. Therefore, peer education is recommended for alleviating psychological problems among patients receiving hemodialysis.

MON-314 Double filtration plasmapheresis in different critical glomerulonephritis in children

Double filtration plasmapheresis (DFPP) was originally used for blood group incompatible renal transplantation, and is recently extended to remove various auto-antibodies in adult patients with immune-mediated diseases. But this technique has seldom been applied in children, much less studied on its efficiency in removing specific plasma components, and safety in children. We performed a prospective and observational study over one year on children undergoing DFPP for various critical renal indications. There were 24 sessions in six patients consisted of 1 male and 5 females, median age 11.5 years (range 8-13 years) and median weight 37.5 kg (range 26.5-58 kg). These patients were allocated into three groups (severe SLE, ANCA-associated vasculitis and C3 glomerulopathy) by different disease. DFPP was performed by using a plasma separator (Plasmaflow OP-08W) and plasma fractionator (EC-20W). All patients had received 2 plasma volumes in each treatment for 3-6 sessions in two consecutive weeks. The pre- and post-procedure plasma samples of pathogenic autoantibodies, IgG, IgA, IgM, fibrinogen, albumin, calcium, phosphate, potassium were analyzed. Complications during the hospital stay were recorded. The result of treatment showed that plasma pathogenic autoantibodies were decreased substantially by 79.03% and 89.78% in either severe SLE or ANCA-associated vasculitis patients after the third session and the last session, respectively. Over the course of successive DFPP sessions, all patients showed improved kidney function and extra-renal manifestations. Cumulative removal of serum IgG, IgA, IgM, C3, fibrinogen, and albumin at the end of last sessions were 54.44%, 46.57%, 79.54%, 44.52%, 71.59%, and 13.29% respectively. Removal of calcium, phosphate, potassium, magnesium and creatinine were not statistically significant. Furthermore, we observed lesser episodes (4.17%) of hypotension with fresh frozen plasma replacements as replacement fluid, and neither bleeding nor membrane anaphylaxis was reported from the treatment. This report shows the efficacy of DFPP is high in pediatric patients with systemic lupus erythematosus, antineutrophil cytoplasmic antibody vasculitis, and C3 glomerulopathy. IgG, IgA, IgM, albumin, and fibrinogen are removed by DFPP. IgG is suboptimally removed whereas IgA, IgM, and fibrinogen are substantially removed. Except for lesser episodes of hypotension, other adverse effects and abnormal bleeding were not found in our patients. Therefore, DFPP can be recommended to treat, as a safe adjunctive therapy, different abnormal immunoglobulins-associated disorders in children.

MON-076 CONTINUOUS AMBULATORY PERITONEAL DIALYSIS (CAPD) IN CHILDREN: A SUCCESSFUL CASE FOR A BRIGHT FUTURE IN A DEVELOPING COUNTRY

Management of Chronic Kidney Disease remains a challenge in developing countries due to the absence of kidney transplant, limited access to extra-renal purification and the low involvement of health policies particularly for children . PD remains a reliable alternative for renal replacement in pediatrics acute and chronic situations. The authors report the first case of successful CAPD in pediatrics in a 13-year-old Senegalese, resident 121 Km from Dakar. This was a 13-year-old boy monitored in the unit since 2017-10-04 for stage V Chronic Kidney Disease (CKD) following a primary nephrotic syndrome by Segmental and Focal Glomerulosclerosis (FSGS) cortico-resistant and cyclo-resistant since he was 11 years old. The patient was anuric. Faced with signs of intolerance in uremia, he first received two successive sessions of haemodialysis then three sessions per week for over 3 months in an adult center. He was switched to CAPD following his parents' choice motivated by a desire to return home. The TENCKOFF catheter was inserted on 2018-03-05 in urology in collaboration with the pediatrics and adult nephrology team. On day 1 after catheter insertion, the peritoneal cavity was rinsed. On day 2 after insertion, the patient had a fever at 39oC, abdominal pain and greenish vomiting. Upon examination, he would scream when his navel is touched. Analysis of the drainage liquid had revealed 650 leucocytes/mm3 with 62% of neutrophils. The dialysate culture was sterile. The hemoculture came back negative. The nasal swab isolated Staphylococcus aureus. The patient received 1g of C3G in each bag of 2L of dialysate associated with a bacitracin+neomycine nasal rub as from day 2 after catheter insertion. The plan proposed to the patient was 4 swabs a day (8am - 12noon - 4pm - 8pm - 8am) with a stasis of isotonic dialysate of 4 hours per session during the day and a stasis of icodextrin for 8 hours at night. The volume of injection per cycle was 1L of dialysate. The peritoneal control fluid at day 7 was sterile. The antibiotic treatment was done by oral route for 14 days. Besides the PD, the patient was receiving anti-hypertensive treatment, vitamin D supplementation, erythropoietin and a CKD diet. After the infection period, an equilibration Test (PET test) revealed a Hyper-permeable peritoneal membrane with D/P creatinine at 0.91. The patient and his mother were trained and assessed on the PD technique. By the end of a month, they had become independent and could recognize the signs or dysfunction of the catheter. Patient assessment during this first month of dialysis revealed an adequate clinical and biological condition. The patient and his mother returned home at Bambey, a town situated 121 Km from Dakar with a tracking sheet n which the weight, blood pressure, temperature and ultra filtrate are noted. After a second month of observation, the patient complained of abdominal pain at the day hospital. The plain abdominal X-ray revealed a catheter migration to the right. The catheter was repositioned in the patient through the use of laxatives. After 4 months of observation, the dialysis was considered adequate on a clinical and biological basis. It was the first case of successful CAPD in the pediatrics unit in this context. Scaling this technique is a challenge for the pediatric nephrologist in developing countries like Senegal.