Successful Acquisition Research Articles

Construction and infection characteristics of a GFP‐labelled Botryosphaeria dothidea causing kiwifruit soft rot disease

AbstractSoft rot disease caused by Botryosphaeria dothidea is one of the most important fungal diseases affecting kiwifruit production. The symptoms of the disease generally appear during the fruit storage period, resulting in difficult disease management and serious economic losses. Therefore, the characterization of the infection mechanism needs to be explored to deepen our understanding of the pathogen and the disease. In this study, a highly pathogenic strain JY‐1, causing kiwifruit soft rot, was isolated and identified as B. dothidea. A polyethylene glycol‐mediated genetic transformation system for B. dothidea JY‐1 was established, enabling the successful acquisition of a green fluorescent protein (GFP)‐labelled strain with stable inheritance. The GFP‐labelled transformant Bd13 was generated and used in the research, and the infection process of kiwifruit tissues was studied through wound inoculation essays and fluorescence labelling microscopy. The results of the present study indicate that the transformant Bd13 not only damaged the kiwifruit fruits but also effectively infected and colonized the leaves and shoots of kiwifruit plants, causing shoot blight and leaf spot. These findings contribute to a deeper understanding of the pathogenic mechanisms underlying kiwifruit soft rot and lay a foundation for further investigations into the interaction between the soft rot pathogen B. dothidea and kiwifruit.

Research on strategic motivation and performance of acquisitions in medical and health field —— A case study of Abiomed and Johnson & Johnson

The medical and healthcare industries are extremely competitive. By mergers and acquisitions, many businesses grow and accept more market share. Businesses can achieve additional development and increase their profit margins through successful mergers and acquisitions. One well-known company in the medical and health sector is Johnson & Johnson. To examine mergers and acquisitions of businesses in the medical and health sector, this article selects the Johnson & Johnson merger and purchase of Abiomed as a case study. It then analyzes the merger and acquisition through performance research and strategic reasoning. The medical and healthcare industries are extremely competitive. By mergers and acquisitions, many businesses grow and take up more market share. Businesses can achieve additional development and increase their profit margins through successful mergers and acquisitions. One well-known company in the medical and health sector is Johnson & Johnson. To examine acquisitions of businesses in the medical and health sector, this article selects the Johnson & Johnson merger and purchase of Abiomed as a case study. It then analyzes the acquisition through performance research and strategic reasoning.

The Role of Stakeholders in Land Acquisition for the Construction of the Gatot Subroto Underpass in Medan

This research analyzes the role of stakeholders in the land acquisition process for the construction of an underpass on Jalan Gatot Subroto Medan. The construction of this underpass infrastructure aims to reduce congestion and improve accessibility and aesthetics of the city of Medan, especially at the Manhattan Mall intersection in Medan. This research uses a qualitative descriptive method by collecting data through interviews, observation and documentation from various related parties, including the government, land owners, contractors, supervisory consultants and local communities. The research results concluded that there were 18 stakeholders divided into 4 (four) quadrants, namely: subject; key players; other supporters and followers. The resulting conclusion is in the form of a division of roles based on the interest and strength quadrants from Reed's (2009) theory. The success of land acquisition for the construction of the Gatot Subroto Medan underpass is determined by the ability of stakeholders to work together

Digital Transformation in Talent Acquisition: An Investigation into the Integration of Big Data Analytics and Management Information Systems for Optimal Hiring Strategies

The primary goal was to empirically investigate the relationships amongst Big Data Analytics (BDA), Management Information System (MIS), optimal hiring strategies, leadership support, and talent acquisition process. This research aimed to fill crucial gaps in the literature by examining how technology adoption and leadership support influence the formulation and effectiveness of optimal hiring strategies, finally impacting talent acquisition results in the Chinese business landscape. Quantitative research was employed, targeting experts and decision-makers in human resource departments across numerous industries in China. The research used a random sampling approach to acquire facts through an online questionnaire, examining responses from 168 participants. Regression and mediation analyses, facilitated by SPSS, were applied to discover the relationships and mechanisms among BDA, MIS, optimal hiring strategies, leadership support, and talent acquisition success. The results discovered a significant and positive relationship between BDA and MIS with the optimal hiring techniques. Moreover, optimal hiring techniques have proven an advantageous association with talent acquisition success. The research similarly showed the mediating role of optimal hiring strategies in translating the advantages of BDA and MIS into talent acquisition success. Leadership support emerged as a moderator, amplifying the relationship between optimum hiring techniques and talent acquisition success. This study contributes empirical proof to the underexplored intersection of leadership support, technology, and talent hiring strategies. The findings offer practical insights for companies aiming to navigate the complexities of recruitment, emphasizing the significance of strategic decision-making, technology integration, and management endorsement in achieving talent acquisition success.

Examining the educational connection and psychological wellness of Chinese EFL students: The functions of productive scaffolding provided by language teachers

The core element of successful language acquisition lies in the active participation of students. When exploring factors that enhance the academic performance of English as a Foreign Language (EFL) students, teacher emotional support has always been a focal point of academic research. With the application of positive psychology, researchers are increasingly focusing on emotions, especially positive emotions, as a central role in the Second Language Acquisition (SLA) field. Over the past decade, researchers have particularly focused on the academic engagement and psychological well-being of language learners, considering them as key factors in improving educational quality. However, specific data on how EFL teachers can enhance students’ psychosocial health and academic engagement through emotional support is still insufficient. Therefore, this study used a questionnaire survey to deeply analyze the data of 1968 Chinese EFL students. Specifically, the research results show that the emotional support provided by teachers can explain up to about 74% and 63% of the differences in EFL students’ educational engagement and mental health, respectively. At the same time, this study also constructed a Structural Equation Modeling (SEM) model, concluding that the CMIN/DF ratio is less than 4. In addition, the research results further reveal the potential important mediating role of Chinese English teachers’ self-efficacy in their resilience, emotional management skills, and mental health. In summary, these findings highlight the importance of establishing positive teacher-student relationships to promote the comprehensive psychological development of students.

Design, Testing, and Validation of a Soft Robotic Sensor Array Integrated with Flexible Electronics for Mapping Cardiac Arrhythmias.

Cardiac mapping is a crucial procedure for diagnosing and treating cardiac arrhythmias. Still, current clinical techniques face limitations including insufficient electrode coverage, poor conformability to complex heart chamber geometries, and high costs. This study explores the design, testing, and validation of a 64-electrode soft robotic catheter that addresses these challenges in cardiac mapping. A dual-layer flexible printed circuit board (PCB) was designed and integrated with sensors into a soft robotic sensor array (SRSA) assembly. Design considerations included flex PCB layout, routing, integration, conformity to heart chambers, sensor placement, and catheter durability. Rigorous SRSA in vitro testing evaluated the burst/leakage pressure, block force for electrode contact, mechanical integrity, and environmental resilience. For in vivo validation, a porcine model was used to demonstrate the successful deployment, conformability, and acquisition of electrograms in both the ventricles and atria. This catheter-deployable SRSA represents a meaningful step towards translating the integration of soft robotic actuators and stretchable electronics for clinical use, showcasing the unique mechanical and electrical performance that these designs enable. The high-density electrode array enabled rapid 2 s data acquisition with detailed spatial and temporal resolution, as illustrated by the clear and consistent cardiac signals recorded across all electrodes. The future of this work will lie in enabling high-density, anatomically conformable devices for detailed cardiac mapping to guide ablation therapy and other interventions.

Motor learning is modulated by dopamine availability in the sensorimotor putamen.

Successful motor skill acquisition requires the dynamic interaction of multiple brain regions, with the striatum playing a critical role in this network. Animal studies suggest that dopaminergic mechanisms are involved in the regulation of motor learning-associated striatal plasticity. In humans, however, the contribution of nigrostriatal dopaminergic transmission to motor learning remains elusive beyond its well-characterized role in initiation and fluent execution of movements. In this prospective observational study, we investigated motor sequence learning in individuals who had undergone 123I-N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane single-photon emission computed tomography for the differential diagnosis of Parkinson's disease (n = 41) and age-matched healthy controls (n = 20). We found that striatal dopamine transporter depletion exhibited distinct spatial patterns that were associated with impairments in motor sequence learning and the manifestation of Parkinsonian motor symptoms, respectively. Specifically, significant associations between striatal dopamine transporter depletion and impairments in motor sequence learning were confined to posterior putaminal regions, whereas significant associations of striatal dopamine transporter depletion with Parkinsonian motor symptom severity showed a widespread spatial pattern across the entire striatal volume with an anterior maximum. Normative functional connectivity analysis revealed that both behavioural domains shared largely overlapping connectivity patterns with the basal ganglia and supplementary motor area. However, apart from connectivity with more posterior parts of the supplementary motor area, significant functional connectivity with primary motor cortical areas was only present for striatal dopamine transporter availability-related modulation of online motor learning. Our findings indicate that striatal dopaminergic signalling plays a specific role in motor sequence learning beyond its influence on mere motor execution, implicating learning-related sensorimotor striatum recruitment and cortico-striatal plasticity as dopamine-dependent mechanisms.

EXPLORING THE ROLE OF L1 LITERACY SKILLS IN L2 READING COMPREHENSION AND VOCABULARY DEVELOPMENT AMONG SENIOR HIGH SCHOOL STUDENTS IN GHANA

This study investigated the relationship between first language (L1) literacy skills and second language (L2) reading comprehension and vocabulary development among students in Ghana. The study was grounded in Cummin’s (1970) Linguistic Interdependence Theory (LIT). The qualitative approach was adopted, and three instruments- focus group discussions, interviews and classroom observations- were used to obtain data from the sample of 300 secondary school students and 40 teachers. The researcher assessed participants' views in L1 literacy domains (phonological awareness, orthographic knowledge, and reading fluency) as well as their views on L2 (English) reading comprehension and vocabulary. The findings revealed a significant positive correlation between students' L1 literacy skills and their achievement in L2 reading comprehension and vocabulary. Those with more advanced abilities in their native language consistently demonstrated higher levels of reading comprehension and broader English vocabulary knowledge. This underscores the critical role of strong foundational literacy in the first language as a precursor to successful second language acquisition. The study also identified key instructional strategies that could help bridge the gap for ESL learners, such as explicit instruction in L1 literacy, structured opportunities for cross-linguistic transfer, and the incorporation of culturally relevant, mother-tongue materials into the curriculum. The implications of these findings for policymakers, curriculum designers, and teachers working to improve educational outcomes for linguistically diverse student populations are discussed.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0799/a.php" alt="Hit counter" /></p>

Bidirectional scanning acquisition of inter-satellite laser links for space gravitational wave detection mission.

Space gravitational wave detection requires establishing laser links between distributed spacecraft for interferometry. Inter-satellite laser link acquisition is an essential step in this process. Considering the spacecraft's miniaturization and reliability, a bidirectional scanning acquisition method is proposed using only field emission electric propulsion and quadrant photodetector. This method does not require additional acquisition sensors and actuators. To improve efficiency while ensuring the acquisition success rate, a constant angular velocity Archimedean spiral scanning guidance law is proposed, and the critical parameters that influence acquisition time and success rate are analyzed. Monte Carlo simulations show that the method can ensure an acquisition success rate of over 90%. Compared with constant linear velocity Archimedean spiral scanning, this method can reduce the acquisition time required to achieve the same success rate by 15%.

Parent-Led Applied Behavior Analysis to Impact Clinical Outcomes for Individuals on the Autism Spectrum: Retrospective Chart Review.

Autism spectrum disorder (ASD) can have traits that impact multiple domains of functioning and quality of life, which can persevere throughout life. To mitigate the impact of ASD on the long-term trajectory of an individual's life, it is imperative to seek early and adequate treatment via scientifically validated approaches, of which applied behavior analysis (ABA) is the gold standard. ABA treatment must be delivered via a behavior technician with oversight from a board-certified behavior analyst. However, shortages in certified ABA therapists create treatment access barriers for individuals on the autism spectrum. Increased ASD prevalence demands innovations for treatment delivery. Parent-led treatment models for neurodevelopmental conditions are effective yet underutilized and may be used to fill this care gap. This study reports findings from a retrospective chart review of clinical outcomes for children that received parent-led ABA treatment and intends to examine the sustained impact that modifications to ABA delivery have had on a subset of patients of Montera, Inc. dba Forta ("Forta"), as measured by progress toward skill acquisition within multiple focus areas (FAs). Parents received ≥40 hours of training in ABA prior to initiating treatment, and patients were prescribed focused (<25 hours/week) or comprehensive (>25-40 hours/week) treatment plans. Retrospective data were evaluated over ≥90 days for 30 patients. The clinical outcomes of patients were additionally assessed by age (2-5 years, 6-12 years, 13-22 years) and utilization of prescribed treatment. Treatment encompassed skill acquisition goals; to facilitate data collection consistency, successful attempts were logged within a software application built in-house. Improved goal achievement success between weeks 1-20 was observed for older age, all utilization, and both treatment plan type cohorts. Success rates increased over time for most FAs, with the exception of executive functioning in the youngest cohort and comprehensive plan cohort. Goal achievement experienced peaks and declines from week to week, as expected for ABA treatment; however, overall trends indicated increased skill acquisition success rates. Of 40 unique combinations of analysis cohorts and FAs, 20 showed statistically significant positive linear relationships (P<.05). Statistically significant positive linear relationships were observed in the high utilization cohort (communication with P=.04, social skills with P=.02); in the fair and full utilization cohorts (overall success with P=.03 for the fair utilization cohort and P=.001 for the full utilization cohort, and success in emotional regulation with P<.001 for the fair utilization cohort and P<.001 for the full utilization cohort); and in the comprehensive treatment cohort (communication with P=.001, emotional regulation with P=.045). Parent-led ABA can lead to goal achievement and improved clinical outcomes and may be a viable solution to overcome treatment access barriers that delay initiation or continuation of care.

Prospective evaluation of extended reality for neonatal intubation education

Purpose360° immersive videos may be useful in procedure-based healthcare settings. We hypothesized that extended reality (XR) neonatal intubation education is a feasible alternative to live demonstration in skill and knowledge transfer.MethodsThis was a prospective single center evaluation of an educational XR intubation video using Premature Anne™ (Laerdal Medical, Stavanger, Norway) comparing to a live demonstration. Participants were randomly allocated to either live demonstration or XR group. Each group received 20 min of teaching from the pediatric respiratory care education specialist, either in person or in video format. Intubation success, knowledge and skill acquisition were measured using a questionnaire and checklist.ResultsWe had a total of 23 participants, XR (n = 11) and live demonstration (n = 12). The groups were heterogeneous in experience level.The XR group was successful at intubating 73% of the time (n = 8), which was not significantly different to the live demonstration group 58% (n = 7) (p = 0.667). For patients who achieved intubation, there was no difference between groups in the mean time to successful intubation; 98 s (SD 73) for the XR group and 65 s (SD 22) for the live demonstration group (p = 0.685).When comparing scores between groups there were no statistically significant differences regarding knowledge scores (p = 0.514), skill scores (p = 0.826) and total scores (p = 0.926).ConclusionThese preliminary findings indicated no significant differences between the XR and live demonstration groups in terms of intubation success, knowledge acquisition, skill performance, total scores or time to successful intubation.

The gustatory receptor BdorGr43a mediated sucrose preference in the feeding of Bactrocera dorsalis

The feeding behavior of animals is pivotal for their reproductive success and energy acquisition. In our study, we found that the Bactrocera dorsalis had a pronounced preference for sucrose among six plant-derived sugars during feeding. Then, we searched the entire genome of B. dorsalis for the gustatory receptors (Grs) responsible for sucrose sensation. Putative gustatory receptors involved in the detection of sweetness, bitterness, CO2 and other unknown functions. Together with phylogenetic analysis, expression profiling, calcium imaging, and CRISPR/Cas9 mediated mutagenesis, we found that BdorGr43a is the key receptor responding to sucrose. Our study elucidated the molecular mechanism underlying the sucrose preferences in the feeding of B. dorsalis. Meanwhile, our results will serve as a reference for the understanding of gustatory sensing in insect. Furthermore, BdorGr43a may serve as an important target for the development of food attractants against the oriental fruit fly.

State ownership and acquisition speed: evidence from China

ABSTRACT Speed is a key driver for the success of acquisitions. Although state ownership is widely believed to affect the management efficiency and action speed of firms, the relationship between state ownership and acquisition speed remains unknown. This paper investigates how firms’ acquisition speed varies with state ownership. Our results suggest that state ownership is associated with slower acquisition speed. Higher administrative hierarchy of the state-owned shareholder is correlation with slower acquisition speed. Reducing the shareholding ratio of state owner and hiring a younger CEO are likely to mitigate the negative correlation between state ownership and acquisition speed.

Digital Transformation in Talent Acquisition: An Investigation into the Integration of Big Data Analytics and Management Information Systems for Optimal Hiring Strategies

The primary goal was to empirically investigate the relationships amongst Big Data Analytics (BDA), Management Information System (MIS), optimal hiring strategies, leadership support, and talent acquisition process. This research aimed to fill crucial gaps in the literature by examining how technology adoption and leadership support influence the formulation and effectiveness of optimal hiring strategies, finally impacting talent acquisition results in the Chinese business landscape. Quantitative research was employed, targeting experts and decision-makers in human resource departments across numerous industries in China. The research used a random sampling approach to acquire facts through an online questionnaire, examining responses from 168 participants. Regression and mediation analyses, facilitated by SPSS, were applied to discover the relationships and mechanisms among BDA, MIS, optimal hiring strategies, leadership support, and talent acquisition success. The results discovered a significant and positive relationship between BDA and MIS with the optimal hiring techniques. Moreover, optimal hiring techniques have proven an advantageous association with talent acquisition success. The research similarly showed the mediating role of optimal hiring strategies in translating the advantages of BDA and MIS into talent acquisition success. Leadership support emerged as a moderator, amplifying the relationship between optimum hiring techniques and talent acquisition success. This study contributes empirical proof to the underexplored intersection of leadership support, technology, and talent hiring strategies. The findings offer practical insights for companies aiming to navigate the complexities of recruitment, emphasizing the significance of strategic decision-making, technology integration, and management endorsement in achieving talent acquisition success.

MEANS OF RESEARCH COMPETENCE FORMATION IN UNIVERSITY STUDENTS DURING BUSINESS FOREIGN LANGUAGE CLASSES

The article examines the means of research competence formation in university students during Business Foreign Language classes. The means of research competence formation through the developing of its key components such as methodological literacy, analytical skills, critical thinking skills and communication skills have been outlined. The development of methodological literacy is seen as a multifaceted process involving the study of the theoretical underpinnings of research, the practical application of methods, the development of critical thinking and data analysis skills. Analytical skills – the ability to process and interpret information – are considered necessary for a deep understanding of language, the effective use of new knowledge and its integration into different contexts. It has been noted that analytical skills help higher education students not only to learn grammar and vocabulary, but also to apply knowledge in real-life situations, to draw logical conclusions and to structure educational information. The development of critical thinking skills is observed as an important element in the successful acquisition of both language and analytical skills. They can be formed by integrating different tasks that encourage students to analyse, evaluate and argue. The development of communication skills is facilitated by the active practice of different formats, with the opportunity not only to learn business vocabulary, but also to master effective strategies of interaction in a work context. The means of developing research competence and its key components in Business English have been indicated. They are discussion of current office work issues, analysis of authentic business texts, translation and interpretation of business documents, presentations (reports), research projects, writing abstracts and business letters.

Axial length acquisition success rates and agreement of two swept-source optical biometers in eyes with dense cataracts.

Swept-source optical coherence tomography-based (SS-OCT) biometers have been used in different clinical studies with the aim of assessing the accuracy of the technique, specifically in eyes with dense cataracts. Our objective is to evaluate the axial length acquisition success rates and agreement of two SS-OCT biometers when measuring axial length and biometric parameters in eyes with dense cataracts. 46 eyes (46 patients) with dense cataracts (LOCS III grade ≥ 4) were measured 3 consecutive times using the Eyestar 900 and Argos SS-OCT biometers. Keratometry (K1, flat and K2, steep), central corneal thickness (CCT), white-to-white (WTW), anterior-chamber-depth (ACD), lens-thickness (LT), and axial length were measured using both biometers. The percentage acquisition success rate and a Bland-Altman analysis to determine the agreement between the biometers were calculated. Corrected and uncorrected distance visual acuity, subjective refraction, and axial length (to assess preoperative axial length accuracy) were measured 1-month post-cataract surgery. The mean LOCS III score was 4.37 ± 0.68. The acquisition success rates for both biometers was 100%. There were statistically significant differences between the two SS-OCT biometers for all parameters evaluated (p < 0.05). The mean differences for K1, K2, CCT, WTW, ACD, LT and axial length were 0.106 D, 0.128 D, -6.347 μm, -0.054 mm, 0.095 mm, 0.110 mm, and -0.036 mm, respectively. The mean pre- and post-surgery axial length difference was -0.036 mm for the Eyestar 900 and -0.020 mm for the Argos. This difference was ≤ 0.1 mm in 97.82% of eyes with the Eyestar 900 and in 100% of eyes with the Argos. SS-OCT biometry successfully measures axial length in dense cataracts. The differences between biometers in some parameters may have a clinically significant impact but should be judged individually. The pre- and post-surgery axial length differences for each biometer can be considered clinically negligible and should not affect the IOL power calculation.

Acquisition integration capabilities and organizational design

Research has yet to explain how firms with acquisition experience can improve their success with acquisitions. With a multi-national sample, we study how acquisition experience can lead to integration capabilities that impact acquisition outcomes. We argue that different types of knowledge (tacit or explicit) and organizational designs (more centralized vs. less centralized) influence the development of integration capabilities. We demonstrate that tacit and explicit knowledge provide multiple paths to acquisition success for acquiring firms, and this can explain conflicting findings in existing research. More specifically, less centralized organizational designs lower the effectiveness of tacit knowledge in developing an integration capability, but centralization is effective for explicit knowledge. Additional implications for management research and practice are provided.

Epigenetic Dynamics in Reprogramming to Dopaminergic Neurons for Parkinson's Disease.

Direct lineage reprogramming into dopaminergic (DA) neurons holds great promise for the more effective production of DA neurons, offering potential therapeutic benefits for conditions such as Parkinson's disease. However, the reprogramming pathway for fully reprogrammed DA neurons remains largely unclear, resulting in immature and dead-end states with low efficiency. In this study, using single-cell RNA sequencing, the trajectory of reprogramming DA neurons at multiple time points, identifying a continuous pathway for their reprogramming is analyzed. It is identified that intermediate cell populations are crucial for resetting host cell fate during early DA neuronal reprogramming. Further, longitudinal dissection uncovered two distinct trajectories: one leading to successful reprogramming and the other to a dead end. Notably, Arid4b, a histone modifier, as a crucial regulator at this branch point, essential for the successful trajectory and acquisition of mature dopaminergic neuronal identity is identified. Consistently, overexpressing Arid4b in the DA neuronal reprogramming process increases the yield of iDA neurons and effectively reverses the disease phenotypes observed in the PD mouse brain. Thus, gaining insights into the cellular trajectory holds significant importance for devising regenerative medicine strategies, particularly in the context of addressing neurodegenerative disorders like Parkinson's disease.

Expression of goat poxvirus P32 protein and monoclonal antibody preparation.

P32 protein serves as a crucial structural component of Goat pox virus (GTPV), which causes a highly virulent infectious disease in sheep and goats. Despite the fact that P32 has been widely expressed in the previous studies, it is difficult to obtain recombinant P32 efficiently. This study aimed to achieve soluble expression of P32 recombinant protein and to develop its specific monoclonal antibody. The gene fragment of P32Δ (GP32Δ) was synthesized by optimizing the coding sequence of amino acids 1-246 of the known goatpox P32 protein. Subsequently, GP32Δ was cloned into a prokaryotic expression vector for expression and purification, resulting in the successful production of soluble recombinant protein rP32Δ. Utilizing rP32Δ, an indirect ELISA method was established by immunizing 6-week-old BALB/c mice with inactivated GTPV as the antigen. Through hybridoma technology, three monoclonal antibody hybridoma cell lines secreting anti-goat pox virus rP32Δ were screened, designated as 2F3, 3E8, and 4H5, respectively. These monoclonal antibodies, classified as IgG1, IgG2a, and IgG2b, respectively, with κappa light chains, were characterized following ascites preparation and purification. Indirect ELISA results demonstrated that the ELISA potency of the three monoclonal antibodies exceeded 1:12800. Furthermore, Western blot analysis revealed specific reactivity of both 3E8 and 4H5 with rP32Δ, while immunofluorescence assays confirmed 3E8's ability to specifically recognize GTPV in cells. The preceding findings demonstrate the successful acquisition of the soluble expressed recombinant P32 protein and its specific monoclonal antibody 3E8 in this study, thereby laying a foundational material basis for the establishment of a GTPV detection method.

Pre- and Postgraduate Training in Communication Skills: the Experience of the West Kazakhstan Marat Ospanov Medical University

In the modern system of medical education, the development of communicative competence is a prerequisite for the training of a qualified medical worker. Successful acquisition of communicative skills allows improving the quality of medical care provided to the population. For this, the learning process must be continuous: from student years to practical medical activity. M. Ospanov West Kazakhstan Medical University has extensive experience in teaching communicative skills, both at the pre-graduate and postgraduate levels of education.