Many scholars and practitioners claim that a supportive organizational culture can enable the successful implementation of knowledge management (KM) technology initiatives. However, little empirical research has been conducted to define the key organizational culture attributes that support more effective application of KM technologies. In this study, the 44 cultural attributes of the organizational culture profile (OCP) and the knowledge management technology profile (KMTP) instruments were used to identify and rank the most critical organizational culture attributes that promote knowledge sharing and KM technology implementation success. Data were collected from 26 US organizations that were implementing KM. The results of the data analysis revealed sufficient evidence to establish a correlation between specific cultural attributes and the successful implementation of knowledge management technology and knowledge sharing.