The high- to ultrahigh-pressure ((U)HP) metamorphic rocks are present within the European Variscan belt between the Bohemian and Iberian massifs (the Galicia-Moldanubian zone) and they are partly incorporated into the Alpine orogenic system. Due to their involvement in various allochthonous units, the affiliation of the (U)HP rocks to the suture zones that were the sites of their initial exhumation, is not always clear. The Bohemian Massif preserves the best evidence of Variscan sutures with clear relationships to the exposed (U)HP rocks. They are the Moldanubian and the Saxo-Thuringian sutures bounding the Teplá-Barrandian block from the SSE and NNE, respectively. The distribution of (U)HP rocks coincides with the boundaries of mantle lithosphere domains, delimited from large-scale seismic anisotropy, and reveals the NW-ward inclination of the Moldanubian mantle lithosphere domain beneath the Teplá-Barrandian block and thus a subduction polarity to the NW. The eastern margin of the Teplá-Barrandian block contains a magmatic arc, which is in direct contact with the Moldanubian orogenic wedge, and both are penetrated by lamprophyre dykes (∼340 Ma), which dates the cessation of the collision-related shortening and crustal consolidation. The overall crustal geometry of the Saxo-Thuringian suture implies the SE-ward polarity of subduction during its formation. However, based on seismic tomography and anisotropy model, the suture at mantle depths appears as a sub-vertical boundary between the Saxo-Thuringian and the Teplá-Barrandian lithosphere domains. The Saxo-Thuringian zone bears evidence of blueschist facies metamorphism in the (para)autochthonous units, which are strongly retrogressed. Compared to the Moldanubian zone, (U)HP rocks are less common in the Saxo-Thuringian zone and occur as nappes and klippes, some of which are exposed near the Moldanubian suture. The similarities of the Saxo-Thuringian (U)HP rocks to those in the Moldanubian zone and their allochthonous positions favour formation of some of the (U)HP rocks along the Moldanubian suture and their subsequent emplacement into the Saxothuringian zone. The Moldanubian suture appears to control the distribution of most of the (U)HP rocks exposed along the European Variscan Belt. They all show similarities regarding lithology, mainly fragments of mantle rocks included in felsic materials, and their granulite-amphibolite facies thermal overprint.