Substantial Similarity Research Articles

Where did my dog go? A pilot study exploring the movement ecology of farm dogs.

Movement ecology is important for advancing our comprehension of animal behavior, but its application is yet to be applied to farm dogs. This pilot study uses combined GPS and accelerometer technology to explore the spatial patterns and activity levels of free roaming farm dogs, Canis familiaris (n = 3). Space-use distributions and range sizes were determined to compare locations visited across days and between individuals, as well as in relation to specific areas of interest. Individual activity levels were analyzed and compared within and between dogs. Space-use patterns and range sizes showed variation among the dogs, although substantial similarity in overall spatial distributions were observed between each pair. Among the dogs, the extent of spatial distribution overlap between days varied, with some individuals exhibiting more overlap than others. The dogs allocated different amounts of their time close to landscape features, and to slow-, medium-, and fast movements. This study demonstrates the potential of using automated tracking technology to monitor space-use and interactions between dogs, livestock, and wildlife. By understanding and managing the free ranging behavior of their farm dogs, farmers could potentially take steps to improve the health and wellbeing of both their dogs and their livestock, limiting disease spread, and reducing the possibility of related economic losses.

Efficient and effective [formula omitted]-core-based community search over attributed heterogeneous information networks

Given a heterogeneous information network (HIN) G and a query node q, community search (CS) over an HIN identifies a cohesive subgraph from G that contains q. Although HINs with attributes on nodes (called AHINs) are prevalent today, the CS over AHINs (CS-AHIN) is ignored in the literature. Though we can convert an AHIN to an attributed homogeneous graph given a meta-path, then apply the CS approaches for attributed homogeneous graphs to solve CS-AHIN, it is problematic for two reasons. (1) Complete graph conversion is time-consuming and unnecessary, because the search only involves the query node's neighborhood, not the entire graph. (2) Existing attribute cohesiveness metrics are not strict enough to reflect substantial similarities among the community's pairwise nodes. To resolve this, we define the CS-AHIN problem atop a strict attribute cohesiveness metric that supports textual and numerical attributes simultaneously. We show the problem is NP-hard. To address it, we propose an exact baseline to return the global optimal result. Then, we propose three heuristic algorithms using a general greedy search framework to speed up the efficiency. Moreover, we present a cohesiveness-aware proximity graph-based index to boost the performance. Comprehensive experimental studies on various real-world datasets demonstrate our method's superiority.

Predição da capacidade última de elementos em concreto armado usando metodologias de análises não linear

Abstract This work aims to investigate the ultimate capacity of reinforced concrete elements in terms of cracking and stiffness loss. Nonlinear finite element analysis (NLFEA) was performed in the ATENA software and compared with a proposed numerical simulation of nonlinear static analysis (NLSA), where material cracking is evaluated based on the loss of tangent stiffness of the elements. The analysis was applied to a low-rise reinforced concrete frame with constant axial loads in the columns, and monotonic lateral load applied at the top beam level. Both methodologies showed good agreement regarding the capacity curve and crack patterns, and the numerical simulation NLSA allowed the identification of the sequence of elements' stiffness loss. The results indicated a substantial similarity between the numerical simulation NLFEA and NLSA and the experimental test, indicating a high potential in predicting the nonlinear behavior of reinforced concrete.

Structure and Dynamics of Type 4a Pili and Type 2 Secretion System Endopili.

Within the highly diverse type four filament (TFF or T4F) superfamily, the machineries of type IVa pili (T4aP) and the type 2 secretion system (T2SS) in diderm bacteria exhibit a substantial sequence similarity despite divergent functions and distinct appearances: T4aP can extend micrometers beyond the outer membrane, whereas the endopili in the T2SS are restricted to the periplasm. The determination of the structure of individual components and entire filaments is crucial to understand how their structure enables them to serve different functions. However, the dynamics of these filaments poses a challenge for their high-resolution structure determination. This review presents different approaches that have been used to study the structure and dynamics of T4aP and T2SS endopili by means of integrative structural biology, cryo-electron microscopy (cryo-EM), and molecular dynamics simulations. Their conserved features and differences are presented. The non-helical stretch in the long-conserved N-terminal helix which is characteristic of all members of the TFF and the impact of calcium on structure, function, and dynamics of these filaments are discussed in detail.

Prediction and optimization of hardened properties of concrete prepared with granite dust and scrapped copper wire using response surface methodology

Urban growth in the developing world has prompted researchers to seek alternatives to fine aggregate due to the severe environmental impact of extensive natural sand depletion. On top of that, the accumulation of non-biodegradable dumps, solid trash such as scrapped copper wire (SCW), and industrial remnants like granite dust (GD) have reached alarming levels. Therefore, incorporating these two waste materials in concrete offers a potentially sustainable solution. The study aims at substituting natural fine aggregate with GD as well as incorporating SCW for predicting and optimizing the compressive and splitting tensile strength of concrete using response surface methodology (RSM). Two independent variables, the volumetric percentages of GD (10 %, 20 %, and 30 %) and SCW (0.1 %, 0.3 %, and 0.5 %) in a concrete mix ratio of 1:1.5:3, were utilized to create probabilistic models for compressive and splitting tensile strength at 7 and 28 days. The experimental design employed central composite design (CCD) of RSM and the results of both ANOVA and regression analysis in terms of several statistical functions demonstrated a strong correlation between the predicted values of the responses and the actual experimental results. The developed models were validated by conducting experiments using optimized proportions of GD (23.32 %) and SCW (0.37 %). Finally, the strengths of the optimum content mix yielding 25.12 MPa and 3.266 MPa, respectively for compressive and splitting tensile at 28 days ensure the efficiency of the models due to the substantial similarity between experimental and predicted values. Therefore, integrating GD and SCW for higher-strength concrete in mass production can be a cost-effective alternative, fostering increased recycling of waste and supporting sustainable growth in building construction.

Анатомическая лексика в якутской оронимии

The article focuses on orographic appellatives and oronyms derived from anatomical terms in the Yakut language through metaphorization. Given that the Yakut oronymy is endangered due to several sociolinguistic and socio-economic reasons, collecting, systematizing, studying, and preserving this specific layer of the Yakut toponymic lexicon in linguistic databases is relevant. We have identified more than 80 anatomical terms that contributed to the Yakut oronymy development. We divided the Yakut anatomical vocabulary used as orographic appellatives into two groups: 1) lexemes denoting the external parts of human and animal bodies and 2) lexemes denoting the internal organs of humans and animals. The comparative analysis covered the following anatomical terms: atax ‘leg’, bas ‘head’, sürex ‘heart’, tumus ‘nose; beak’, kulgaax ‘ear’, töbö ‘head’, meyii ‘brain’, emiy ‘udder’. The comparison has demonstrated a substantial similarity in the anatomical vocabulary used as orographic appellatives in the Turkic languages. However, some Turkic languages feature divergence in terms of content, possibly resulting from the influence of contact languages (related and unrelated). The abundance and variety of metaphorical anatomical terms in different Turkic languages may also be due to the physical and geographical features of the terrain on which they function. Given the above, the anatomical vocabulary can be considered an additional source for understanding the formation patterns and features of the Turkic-Mongolian geographical vocabulary of Siberia.

중국의 TV방송 프로그램 포맷 보호에 관한 고찰

A broadcast format can be thought of as the framework, containing elements that distinguish it from other programs with fixity and identifiability, such as the program name, stage setting, and background music. There is some debate as to whether program formats can be legally protected under traditional copyright principles based on the idea-expression dichotomy.
 According to China's copyright law, for an intellectual product to be legally protected as a work, the following three conditions must be met: (1) the work must be an intellectual achievement in the field of literature, art, and science; (2) it must have originality; and (3) it must be expressible in a certain form. Given these principles, there are practical limitations to how broadcast program formats can be included in the category of copyrighted works to provide protection under the existing legal order. One way to overcome these limitations is to consider the approach method, which focuses on the substantial similarity of the two broadcast programs at issue.
 On the other hand, in the broadcast program market, subsequent programs created by copying and plagiarizing an existing successful broadcast format may constitute unfair imitation under the Unfair Competition Law and should be sanctioned under the law. If a format creator trades in format rights or attracts investment based on a format, it is an obvious commercial activity. Therefore, if a broadcast program format is in competition, it is reasonable for the format creator's behavior to be regulated by the Anti-Unfair Competition Law. However, there are certain limitations to the ability of the Unfair Competition Act to regulate infringement of broadcasting formats.
 In the future, as trade between Korea and China in the cultural content industry expands, it is expected that the number of broadcast program formats produced in China will increase as in the past. In light of this, the discussion on broadcast program formats in China and the study on how to legally protect the rights of authors is also relevant to Korea.

Unveiling differential expression profiles of the wheat DOG1 gene family and functional analysis of the association between TaDOG1-1 and heat stress tolerance in transgenic Arabidopsis

High temperatures can significantly impact wheat growth and grain yields during the grain-filling stage. In this study, we identified genes that respond to high-temperature stress during the grain-filling stage. We also identified and characterized 24 novel genes of the DOG1 gene family in hexaploid wheat. Motif analysis and conserved domain search revealed substantial similarities among TaDOG1 family members. Phylogenetic analysis demonstrated the evolutionary conservation of the TaDOG1 family across various plant species. Tissue-specific expression profiling indicated consistent patterns, with TaDOG1 genes predominantly expressed in stem tissues. Only TaDOG1-1 exhibited enhanced expression, particularly during hard dough and ripening stages. TaDOG1-1 and TaDOG1-7 exhibited increased expression under heat stress during the grain-filling stage, indicating their heat-responsive nature. Cis-element analysis revealed potential regulatory motifs, suggesting the involvement of TaDOG1-1 and TaDOG1-7 in stress tolerance mechanisms. Yeast two-hybrid screening revealed interacting proteins, including stress-responsive and grain development-associated proteins. To understand the biological function, we overexpressed TaDOG1-1 in Arabidopsis plants and observed enhanced thermotolerance under basal heat stress. Under heat stress, the transgenic plants exhibited increased biomass and elevated expression levels of heat-responsive genes. Furthermore, TaDOG1-1–overexpressing plants showed improved survival rates under soil heat stress, along with a greater accumulation of antioxidant enzymes in leaves. In this study, the identification and functions of the DOG1 gene family provide valuable insights for developing genetic engineering strategies aimed at improving wheat yield under high-temperature stress.

Comprehensive Assessment of the Effectiveness of the Application of Foam and Extruded Polystyrene in the Railway Substructure

This article presents the authors’ comprehensive evaluation of the application of specific foam thermal insulation materials, namely expanded polystyrene (EPS) and extruded polystyrene (XPS), within railway substructures. The assessment extends to real-world conditions on the tracks of Slovak Railways (ŽSR), which share substantial similarities with other countries’ railway networks. The assessment of structural composition and material selection considers these technical aspects, while technological feasibility and the environmental implications associated with material production, delivery, and incorporation into railway construction do not. Additionally, the thermal insulation materials’ qualities are compared against conventional railway substructure materials. In these conventional setups, the thermal insulation layer often incorporates crushed aggregate of specified fractions and parameters in line with legislative standards. This article complements previous research conducted at the University of Žilina, focusing on the application of various thermal insulation materials within railway substructures. These materials were both experimentally tested (scale of 1:1) and numerically modelled, with results previously published by the authors. The published works detail the utilisation of diverse thermal insulation materials in railway substructures, primarily evaluating two crucial technical parameters: the protection of the subgrade surface against adverse effects of frost and, secondarily, their impact on the deformation resistance of the railway substructure.

Compartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma

BackgroundOvarian carcinosarcoma (OCS) is an exceptionally aggressive and understudied ovarian cancer type harbouring distinct carcinomatous and sarcomatous compartments. Here, we seek to identify shared and compartment-specific events that may represent potential therapeutic targets and candidate drivers of sarcomatous compartment formation through epithelial-to-mesenchymal transition (EMT).MethodsWe performed multiomic profiling (exome sequencing, RNA-sequencing, microRNA profiling) of paired carcinomatous and sarcomatous components in 12 OCS cases.ResultsWhile paired sarcomatous and carcinomatous compartments demonstrate substantial genomic similarities, multiple loci are recurrently copy number-altered between components; regions containing GNAS and SRC are recurrently gained within the sarcomatous compartment. CCNE1 gain is a common event in OCS, occurring more frequently than in high grade serous ovarian carcinoma (HGSOC). Transcriptomic analysis suggests increased MAPK activity and subtype switching toward poor prognosis HGSOC-derived transcriptomic subtypes within the sarcomatous component. The two compartments show global differences in microRNA profiles, with differentially expressed microRNAs targeting EMT-related genes (SIRT1, ZEB2) and regulators of pro-tumourigenic pathways (TGFβ, NOTCH); chrX is a highly enriched target of these microRNAs and is also frequently deleted across samples. The sarcomatous component harbours significantly fewer CD8-positive cells, suggesting poorer immune engagement.ConclusionCCNE1 gain and chrX loss are frequent in OCS. SRC gain, increased GNAS expression and microRNA dysregulation represent potential mechanisms driving sarcomatous compartment formation.

Rice ILI atypical bHLH transcription factors antagonize OsbHLH157/OsbHLH158 during brassinosteroid signaling.

Brassinosteroids (BRs) are a group of steroid hormones that play crucial roles in plant growth and development. Atypical bHLH transcription factors that lack the basic region for DNA binding have been implicated in BR signaling. However, the underlying mechanisms of atypical bHLHs in regulation of rice (Oryza sativa) BR signaling are still largely unknown. Here, we describe a systematic characterization of INCREASED LEAF INCLINATION (ILI) subfamily atypical bHLH transcription factors in rice. A total of 8 members, ILI1 to ILI8, with substantial sequence similarity were retrieved. Knockout and overexpression analyses demonstrated that these ILIs play unequally redundant and indispensable roles in BR-mediated growth and development in rice, with a more prominent role for ILI4 and ILI5. The ili3/4/5/8 quadruple and ili1/3/4/7/8 quintuple mutants displayed tremendous BR-related defects with severe dwarfism, erect leaves, and sterility. Biochemical analysis showed that ILIs interact with OsbHLH157 and OsbHLH158, which are also atypical bHLHs and have no obvious transcriptional activity. Overexpression of OsbHLH157 and OsbHLH158 led to drastic BR-defective growth, whereas the osbhlh157 osbhlh158 double mutant developed a typical BR-enhanced phenotype, indicating that OsbHLH157 and OsbHLH158 play a major negative role in rice BR signaling. Further transcriptome analyses revealed opposite effects of ILIs and OsbHLH157/OsbHLH158 in regulation of downstream gene expression, supporting the antagonism of ILIs and OsbHLH157/OsbHLH158 in maintaining the balance of BR signaling. Our results provide insights into the mechanism of BR signaling and plant architecture formation in rice.

CSF proteomics in autosomal dominant Alzheimer’s disease highlights parallels with sporadic disease

AbstractBackgroundAutosomal dominant Alzheimer’s disease (ADAD) offers a unique opportunity to study pathophysiological changes in a relatively young population with few comorbidities. A comprehensive investigation of proteome changes occurring in ADAD could provide valuable insights into AD‐related biological mechanisms and uncover novel biomarkers and therapeutic targets. Furthermore, ADAD might serve as a model for sporadic AD, but in‐depth proteome comparisons are lacking. We aimed to identify dysregulated CSF proteins in ADAD and determine the degree of overlap with sporadic AD.MethodUsing proximity extension‐based immunoassays (PEA) by Olink, we measured 1472 proteins in CSF of APP or PSEN1 mutation carriers (n = 22) and age‐ and sex‐matched controls (n = 20) from the Amsterdam Dementia Cohort. We compared protein abundance between groups using two‐sided t‐tests and identified enriched biological pathways. Using the same protein panels in paired plasma samples, we investigated correlations between CSF proteins and their plasma counterparts. Finally, we compared our results with recently published PEA data from an international cohort of sporadic AD (n = 230) and non‐AD dementias (n = 301). All analyses were false discovery rate‐corrected.ResultWe detected 66 differentially abundant CSF proteins (65 increased, one decreased) in ADAD compared to controls (q<0.05). The most strongly upregulated proteins (fold change >1.8) were related to immunity (CHIT1, ITGB2, SMOC2), cytoskeletal structure (MAPT, NEFL) and tissue remodeling (TMSB10, MMP‐10). Significant CSF‐plasma correlations were found for the upregulated proteins SMOC2 and LILR1B. 36 of the 66 differentially expressed proteins had been previously measured in the sporadic dementias cohort, 34 of which (94%) were also significantly upregulated in sporadic AD, with a strong correlation between the fold changes of these proteins in both cohorts (rs = 0.730, p<0.001). 29 of these 36 proteins (81%) were also upregulated among non‐AD patients with suspected AD co‐pathology.ConclusionThis CSF proteomics study demonstrates substantial biochemical similarities between ADAD and sporadic AD, suggesting involvement of the same biological processes. Besides known AD‐related proteins, we identified several relatively novel proteins, such as TMSB10, MMP‐10 and SMOC2, which have potential as novel biomarkers. With shared pathophysiological CSF changes, ADAD study findings might be translatable to sporadic AD, which could greatly expedite therapy development.

Environmental effects rather than relatedness determine gut microbiome similarity in a social mammal.

In social species, group members commonly show substantial similarity in gut microbiome composition. Such similarities have been hypothesized to arise either by shared environmental effects or by host relatedness. However, disentangling these factors is difficult, because group members are often related, and social groups typically share similar environmental conditions. In this study, we conducted a cross-foster experiment under controlled laboratory conditions in group-living Damaraland mole-rats (Fukomys damarensis) and used 16S amplicon sequencing to disentangle the effects of the environment and relatedness on gut microbiome similarity and diversity. Our results show that a shared environment is the main factor explaining gut microbiome similarity, overshadowing any effect of host relatedness. Together with studies in wild animal populations, our results suggest that among conspecifics environmental factors are more powerful drivers of gut microbiome composition similarity than host genetics.

Exploring audiovisual speech perception in monolingual and bilingual children in Uzbekistan

This study aimed to investigate the development of audiovisual speech perception in monolingual Uzbek-speaking and bilingual Uzbek–Russian-speaking children, focusing on the impact of language experience on audiovisual speech perception and the role of visual phonetic (i.e., mouth movements corresponding to phonetic/lexical information) and temporal (i.e., timing of speech signals) cues. A total of 321 children aged 4 to 10 years in Tashkent, Uzbekistan, discriminated /ba/ and /da/ syllables across three conditions: auditory-only, audiovisual phonetic (i.e., sound accompanied by mouth movements), and audiovisual temporal (i.e., sound onset/offset accompanied by mouth opening/closing). Effects of modality (audiovisual phonetic, audiovisual temporal, or audio-only cues), age, group (monolingual or bilingual), and their interactions were tested using a Bayesian regression model. Overall, older participants performed better than younger participants. Participants performed better in the audiovisual phonetic modality compared with the auditory modality. However, no significant difference between monolingual and bilingual children was observed across all modalities. This finding stands in contrast to earlier studies. We attribute the contrasting findings of our study and the existing literature to the cross-linguistic similarity of the language pairs involved. When the languages spoken by bilinguals exhibit substantial linguistic similarity, there may be an increased necessity to disambiguate speech signals, leading to a greater reliance on audiovisual cues. The limited phonological similarity between Uzbek and Russian might have minimized bilinguals’ need to rely on visual speech cues, contributing to the lack of group differences in our study.

Abstract 13828: Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARADIGM-HF Proteomic Sub-Study

Introduction: Prognostic markers and biological pathways linked to detrimental clinical outcomes in heart failure with preserved ejection fraction (HFpEF) remain incompletely defined. Goal: To identify serum proteins associated with risk for HF hospitalization (HFH) and cardiovascular (CV) death in patients with HFpEF, including proteins with differential associations with clinical outcomes in HFpEF compared to HFrEF. Methods: We measured serum levels of 4123 unique proteins in 1117 patients with HFpEF in the PARAGON-HF trial using a modified aptamer proteomic assay. Baseline protein concentrations significantly associated with total HFH and CV death were identified by recurrent events regression, accounting for multiple testing, adjusted for age, sex, treatment, and anticoagulant use, and compared to 2515 patients with HFrEF from the PARADIGM-HF and ATMOSPHERE trials. Results: We identified 288 proteins to be robustly associated with the risk of HFH and CV death (335 events over an average of 2.7 years of follow-up) in a HFpEF trial population. Proteins most strongly related to HFpEF outcomes included B2M, TIMP1, SERPINA4, and SVEP1 ( Figure ). Protein-outcome associations in patients with HFpEF did not markedly differ compared to HFrEF. Just 3 proteins (APOE, RTF1, and VWF) were differentially associated with outcomes between the HF subtypes (FDR <0.05). A proteomic risk score derived in HFpEF patients was not superior to a previous proteomic score derived in HFrEF nor to clinical risk factors, NT-proBNP, or high-sensitivity cardiac troponin. Conclusions: Numerous serum proteins linked to metabolic, coagulation, and extracellular matrix regulatory pathways were associated with worse HFpEF prognosis. SVEP1, a cell adhesion protein recently identified as a HFrEF prognosis biomarker, also strongly predicted risk in HFpEF. Our results demonstrate substantial similarities in serum proteomic risk markers across the EF spectrum.

A telencephalon cell type atlas for goldfish reveals diversity in the evolution of spatial structure and cell types.

Teleost fish form the largest group of vertebrates and show a tremendous variety of adaptive behaviors, making them critically important for the study of brain evolution and cognition. The neural basis mediating these behaviors remains elusive. We performed a systematic comparative survey of the goldfish telencephalon. We mapped cell types using single-cell RNA sequencing and spatial transcriptomics, resulting in de novo molecular neuroanatomy parcellation. Glial cells were highly conserved across 450 million years of evolution separating mouse and goldfish, while neurons showed diversity and modularity in gene expression. Specifically, somatostatin interneurons, famously interspersed in the mammalian isocortex for local inhibitory input, were curiously aggregated in a single goldfish telencephalon nucleus but molecularly conserved. Cerebral nuclei including the striatum, a hub for motivated behavior in amniotes, had molecularly conserved goldfish homologs. We suggest elements of a hippocampal formation across the goldfish pallium. Last, aiding study of the teleostan everted telencephalon, we describe substantial molecular similarities between goldfish and zebrafish neuronal taxonomies.

Three Cases of Tickborne Francisella tularensis Infection, Austria, 2022.

Tularemia is increasing in Austria. We report Francisella tularensis subspecies holarctica isolated from 3 patients who had been bitten by arthropods. Next-generation sequencing showed substantial isolate similarity. Clinicians should consider bloodstream F. tularensis infections for patients with signs/symptoms of ulceroglandular tularemia, and surveillance of potential vectors should be intensified.

A Comparative Glance At Teaching Practice of Mother Tongue Teacher Candidates in Türkiye and United Kingdom

This research aimed to determine how prospective secondary school language teachers conduct their teaching practicum in the United Kingdom and Türkiye. The study was designed using a multiple-case holistic design. Accordingly, data for the research were collected through document analysis and interviews. Data related to the teaching practicum in the Turkish Language Teaching program at Kırşehir Ahi Evran University Faculty of Education in Türkiye were obtained through document analysis. Data regarding the teaching practicum in the Postgraduate Certificate in Education program for secondary English teaching at the University of Reading Faculty of Education in the United Kingdom were obtained through document analysis and interviews with faculty members at the institution. It is evident that while the instructional content of teaching practicums in both nations exhibits substantial similarities, a notable disparity emerges with regard to the temporal extent of the practicum experience afforded to prospective secondary school language educators. As a result, the process of teaching practicums for secondary school language teacher candidates differs between Türkiye and the UK in terms of practicum hours, school diversity, and assessment methods.

Genomes of a Novel Group of Phages That Use Alternative Genetic Code Found in Human Gut Viromes.

Metagenomics provides detection of phage genome sequences in various microbial communities. However, the use of alternative genetic codes by some phages precludes the correct analysis of their genomes. In this study, the unusual phage genome (phAss-1, 135,976 bp) was found after the de novo assembly of the human gut virome. Genome analysis revealed the presence of the TAG stop codons in 41 ORFs, including characteristic phage ORFs, and three genes of suppressor tRNA. Comparative analysis indicated that no phages with similar genomes were described. However, two phage genomes (BK046881_ctckW2 and BK025033_ct6IQ4) with substantial similarity to phAss-1 were extracted from the human gut metagenome data. These two complete genomes demonstrated 82.7% and 86.4% of nucleotide identity, respectively, similar genome synteny to phAss-1, the presence of suppressor tRNA genes and suppressor TAG stop codons in many characteristic phage ORFs. These data indicated that phAss-1, BK046881_ctckW2, and BK025033_ct6IQ4 are distinct species within the proposed Phassvirus genus. Moreover, a monophyletic group of divergent phage genomes containing the proposed Phassvirus genus was found among metagenome data. Several phage genomes from the group also contain ORFs with suppressor TAG stop codons, indicating the need to use various translation tables when depositing phage genomes in GenBank.

How indigenous australians try to preserve themselves

The article discusses personal and collective life ways of native people residing in remote settlements of the Cape York Peninsula, Australia, and offers a number of observations on the native population of Central Australia. It is drawn on the authors’ field materials collected in 2005, 2007-2009, 2015, and 2022. If set against the backdrop of the likewise framed project exploring the Evens and Evenkis of Eastern Siberia, the situation in faraway settlements of Australian Aboriginal people manifests both substantial similarities and important differences. Neither in the past when the colonization began to unfold, nor in the present did the Aboriginal people, for the most part, willingly join the commercial and entrepreneurial activities of the Australian mainstream circles or get involved in trade and economic relationships with the newcomers. They rather resisted, and still do, the authorities' and entrepreneurs' attempts at getting them involved in such relationships. We argue that the underlying reason behind that is the very character of the local traditional culture, the key aspects of which are consciously and resiliently preserved - even if sometimes in a transformed or deviant manner - by the native people.