Subsequent Hip Fracture Research Articles

The second hip fracture. An epidemiologic study.

We studied a group of 151 patients who were treated for various types of fractures and who all had a history of a previous hip fracture. A subgroup with new hip fractures had few of their second fractures on the same side as the initial fracture. It appears that a hip fracture reduces the risk of a subsequent hip fracture on the same side to one fourth and that cervical fractures reduce this risk to one sixth. A tendency was found for the hip fracture to be of the same type as the previous one. The time between the first and the second hip fracture was twice as long in those with a previous cervical fracture as in those with a previous trochanteric fracture.

Colles?? Fracture and Subsequent Hip Fracture Risk

The prevention of hip fractures, a major cause of morbidity and mortality in the elderly, is hampered by insufficient knowledge of the population at risk. A Colles' fracture associated with minor trauma is indicative of an overall 50% increase in the risk of a subsequent hip fracture. The relative risk of a subsequent hip fracture is greater for men with Colles' fracture (RR = 6.4) than for women (RR = 1.3). Among women, the risk is increased more than twofold for those whose Colles' fractures occurred at the age of 70 or older but is not increased for younger women. That greater predictive power was not achieved may be due to differences in the pathophysiology of osteoporosis at various fracture sites.

Examination of Prevalence Rates of Possible Risk Factors in a Population with a Fracture of the Proximal Femur

No statistical increase in the prevalence of either diabetes, rheumatoid arthritis or primary hyperparathyrodism was found among the hip fracture patient population. Since the relative risks for these diseases is small, the statistics suggest that these conditions are either noncontributory or represent only a minor risk factor in the overall pathogenesis of hip fractures. About 20% of the hip fracture patients had a history of other identifiable risk factors such as thyrotoxicosis, hemiplegia, malabsorption syndromes and corticosteroid therapy. Of these conditions only thyrotoxicosis could be evaluated by comparison of prevalence rates, and a significant increase was found among the fracture patients. A highly significant correlation was found between the side of a previous hemiplegia and side of he subsequent hip fracture; this may be due to the development of disuse osteoporosis in the hemiplegic limb. Recent reports have shown that a reduction in the number of hip fractures is associated with a high calcium intake or prophylactic estrogen therapy. Preventive therapy in patients with hemiplegia, thyrotoxicosis, or other predisposing conditions leading to osteopenia might result in a further reduction of the hip fracture rate.

Bisphosphonates can prevent recurrent hip fracture and reduce the mortality in osteoporotic patient with hip fracture: A meta-analysis.

Objective:This meta-analysis was conducted to investigate the efficacy of bisphosphonates for preventing recurrent hip fracture and reducing the mortality of elderly patient with hip fracture.Methods:The databases of Pubmed, Embase and Cochrane Library were searched. All randomized or prospective matched controlled trials that assessed the efficacy of bisphosphonate for elderly patients with hip fracture were included. Two researchers independently extracted data of the included articles and assessed the methodological quality which was assessed based on Jadad scoring system or Newcastle-Ottawa scale. The second hip fracture incidence, mortality and complications were compared between bisphosphonates and control groups.Results:Four studies including 3088 patients were included. Results showed that there were significant difference of second hip fracture (P<0.05) and mortality (P<0.05) between bisphosphonates group and control group. While no significant intergroup difference were observed for all complications.Conclusions:Bisphosphonates can prevent subsequent hip fracture, reduce the mortality, and does not increase the overall complications in elderly patients with hip fracture.