Herein, the effects of the bottom shape of the submerged entry nozzle (SEN) on the molten steel flow and size distribution of argon bubbles are analyzed in a steel continuous casting slab strand using multiple‐size‐group approach. The type of nozzle bottom includes the well bottom, flat bottom, and mountain bottom. Most of argon bubbles are larger than 4.5 mm inside the SEN and the mold at the three types of nozzles. The frequency distribution of bubbles inside the SEN increases from 28.29% to 32.65% and 35.74% for 5.0–5.5 mm bubbles and decreases from 53.71–50.49% and 47.38% for 5.5–6.0 mm bubbles with the nozzle bottom varied from the flat to mountain and well shape, respectively. The number density of argon bubbles with 4.0–5.5 mm diameter in the mold decreases and increases for 5.5–6.0 mm bubbles with the nozzle bottom varying from the well to flat and mountain shape, respectively. In addition, the results of the industrial trials show that inclusions adhesion and aggregation at the bottom of the nozzle are eliminated using the flat bottom SEN casting. Meanwhile, the mechanism of SEN clogging under the different types of nozzle bottoms is analyzed.