Subjective Perception Of Quality Research Articles

Enhancement of Subjective Quality of Life Following Surgical Intervention in Patients With Drug-Resistant Epilepsy: A Depressive Symptom-Independent Outcome.

To evaluate the impact of depressive symptoms on the subjective perception of quality of life in patients with drug-resistant epilepsy (DRE) after surgical treatment for seizures. Methods: A case-control study with DRE patients who received surgical treatment (n=19) and matched non-operated patients (n=23). We assessed the quality of life using the Subjective Handicap of Epilepsy (SHE) scale, alongside measuring depressive symptoms using the Beck Depression Inventory (BDI). The mean age of the participants was 45 years, with females constituting 52.4% of the patients. A majority (73.8%) had been diagnosed with temporal lobe epilepsy. Those who had undergone surgical intervention showed significantly enhanced performance across all quality-of-life domains on the SHE scale independently of depressive symptoms. The domains of "Work and Activity,""Physical Health,"and "Self-Perception" displayed the greatest improvements, with the surgical group's averages outperforming the control group by factors of 1.87, 2.53, and 2.81, respectively. Influential differences impacting the quality-of-life scores included seizure frequency, the quantity of antiepileptic drugs utilized, and the incidence of convulsive seizures. The findings suggest that surgical control of seizures in drug-resistant focal epilepsy is associated with improvement in quality of life across various domains, independently of the depressive symptoms of the patients.

Comparison of quality of life with two trifocal intraocular lenses under different lighting conditions

Aims/Purpose: To evaluate the effect of two types of trifocal intraocular lenses on the visual quality of patients undergoing cataract surgery by assessing contrast sensitivity, halo perception and subjective visual satisfaction under photopic and mesopic lighting conditions.Methods: Observational, prospective, cross‐sectional study. The study was conducted at the Hospital Universitario Sanitas la Moraleja in Madrid. The study followed the principles of the Declaration of Helsinki. The sample included 16 cataract or lensectomy patients with bilateral implantation of one of the two intraocular lenses (IOL) under study: 20 eyes implanted with FineVision and 12 eyes implanted with PanOptix. After 30 days after surgery, contrast sensitivity was measured with the CSV‐1000 test (2.5 metres) for four spatial frequencies (3, 6, 12 and 18 c/g), halo perception was assessed with the Halo.V.1 software and finally quality of life was assessed with the VF‐14 questionnaire. A p‐value < 0.05 was considered a criterion for statistical significance.Results: Analysis of contrast sensitivity under photopic conditions showed significant differences greater for the FineVision lens of 0.15 log units at 3 c/g and 12 c/g frequencies between the two lenses under photopic illumination conditions (p‐value 0.034). However, there were no statistically significant differences in mesopic illumination conditions. Furthermore, there was no statistically significant difference when purchasing the perception of halos, with a p‐value (0.149). On the other hand, patients' subjective perception of quality of life scored worse in night vision (p‐value 0.023) and near vision (p‐value 0.046) when comparing the PanOptix lens and the FineVision.Conclusions: The FineVision IOL lens provides better contrast sensitivity in photopic illumination conditions than the PanOptix. However, in mesopic conditions, both IOL designs provide similar contrast sensitivity values for the far distance. On the other hand, although the lenses did not show statistically significant differences in halo perception, the FineVision shows better vision satisfaction results during night driving than the PanOptix.

Research on Language Evolution and Language Diversity Based on Chinese Speech Pitch Deviation Features

Abstract This paper constructs a Chinese speech evaluation system based on the characteristics of the vocal mechanism of Chinese speech and uses the detection framework of statistical speech recognition to realize the automatic detection function of pronunciation bias. Assuming that the amplitude spectra of speech and noise obey the generalized Gamma distribution and Gaussian distribution, respectively, the MMSE estimator of the logarithmic spectrum of the speech signal is derived. The speech presence probability under the generalized Gamma speech model is derived as a correction to the MMSE estimation based on language evolution and diversity features. The correct recognition rate of the proposed algorithm reaches 64%, which indicates that the proposed algorithm can effectively suppress the interference of convolutional noise on the speech signal features and improve the subjective perceptual quality of diverse languages.

Satisfaction with primary health care in Ukraine in 2016–2020: A difference-in-differences analysis on repeated cross-sectional data

The aim of this study is to examine the general satisfaction with primary health care services in Ukraine among service users and nonusers before and after the implementation of the capitation reform in 2017–2020. Data from a repeated cross-sectional household survey ‘Health Index. Ukraine’ in 2016–2020 were used. The survey had a sample size of over 10 000 participants per survey round. Effects were estimated using difference-in-differences methods based on matched samples. Our findings show that in general, respondents are ‘rather satisfied’ with the services of district/family doctors and pediatricians. Satisfaction with family doctors comprised 72.1 % (users) and 69.2 % (nonusers) in 2016; and 75.3 % and 71.9 % in 2020. For pediatrician services, these shares were 73.6 % (users) and 71.1 % (nonusers) in 2016; 74.7 % and 70.2 % in 2020. Our study also revealed an increase in satisfaction with the district/family doctor over time. However, this does not seem to be due to the reform. The results for pediatrician services were mixed. Why satisfaction with primary care is fairly high and slightly increasing over time is unclear. However, we offer several possible explanations, such as low expectations of primary health care, subjective perception of quality of health care services, improved access and affordability, and general improvements in primary health care settings not directly linked to the reform.

Impact of Monocular and Binocular Visual Function Parameters on Vision-Related Quality of Life in Glaucoma.

This study describes the impact of monocular (M/O) and binocular (B/O) visual function decline, primarily the contrast sensitivity (CS) and visual field (VF) defect severity and its location, on the subjective perception of quality of life (QoL) among the Indian glaucoma population with spared central acuity. To investigate the influence of M/O and B/O visual function parameters on vision-related QoL (VRQoL) in glaucoma with spared central visual acuity. Glaucoma subjects underwent M/O and B/O visual acuity, CS assessment, followed by the M/O perimetry from which the integrated VF was estimated (B/O summation method). VRQoL was evaluated using the Glaucoma Quality Of Life-15 (GQL-15) and Visual Function Questionnaire-Utility Index (VFQ-UI) questionnaires. The relationship between CS and VF defect (VFD) with the composite VRQoL scores was analyzed. A total of 154 glaucoma subjects with a median age of 61 (range: 24-83) years were enrolled. Subjects with severe VFD reported poor composite scores for GQL-15 and VFQ-UI when compared with unilateral and mild groups ( P < 0.001, Dunn post hoc). Both the composite scores were negatively correlated with M/O and B/O CS and VF mean deviation ( r range: -0.3 to -0.5, P < 0.001, Spearman rank correlation). B/O VFD in the inferior central zone contributed to poor GQL-15 score [odds ratio: 1.14 (95% CI: 1.10-1.29), P = 0.04] irrespective of sex, whereas females with increasing B/O VFD reported poor QoL score in VFQ-UI [odds ratio: 4.09 (95% CI: 1.77-9.43), p=0.003]. Poor GQL-15 and VFQ-UI scores were reported with increasing disease severity. B/O VFD in the inferior central region was found to contribute predominantly to the poor GQL-15 scores while both disease severity and sex influenced VFQ-UI scores.

In Search of the Niche—Targeting Lamb Meat Consumers in North-East Germany to Communicate the Ecosystem Services of Extensive Sheep Farming Systems

Extensive sheep farming systems provide numerous ecosystem services, most of which consumers are not aware of. Consumers’ subjective quality perception relates to intrinsic and extrinsic quality attributes. Extrinsic quality attributes, like animal welfare, conservation of biodiversity, and regional and sustainable lamb meat production, meet the expectations of meat consumers. Communication of quality attributes can support consumers’ willingness to buy and pay a premium price, as well as producers’ economic viability. Previous studies focused on consumers’ perception of intrinsic quality attributes, while it is our objective to analyse the target group-specific communication of extrinsic quality attributes of extensive sheep farming. An online survey with 387 valid respondents included lamb meat consumers in Berlin-Brandenburg and revealed their consumption patterns. The sample is representative of Berlin-Brandenburg in net household income, population division and gender, while academics and respondents over 50 years were overrepresented. The survey addressed demographics, meat consumption and purchasing behaviour, preferences for different lamb meat products, purchasing motives and barriers, perception of communication messages and personal initiative for the purchase of regional lamb. Via Principal Component Analysis (PCA) and Cluster Analysis, we identified two key target groups for regionally produced lamb meat: “Foodies” and “Cooking enthusiasts”. Guided by Alphabet theory with its specific focus on Knowledge, Information seeking behaviour and purchasing Habit, we derive recommendations for target-group-specific communication of regionally produced lamb meat. “Foodies” showed a high potential for direct marketing and personal storytelling of sheep farmers. “Cooking enthusiasts” are best addressed through print and online marketing with a focus on cooking and personal health.

The influence of personality on the quality of vision after multifocal intraocular lens implantation.

To assess the possible correlation between patients' personality traits and subjective perception of quality of vision (QoV), after multifocal intraocular lens (mIOL) implantation. patients who had bilateral implantation of a non-diffractive X-WAVE or a trifocal lens were assessed 6 months postoperatively. Patients answered the NEO-Five Factor Inventory (NEO-FFI-20) questionnaire ("Big Five five-factor personality model") to examine their personality. Six months following surgery, patients were asked to fill a QoV questionnaire where they graded the frequency of 10 common visual symptoms. Primary outcomes were to evaluate the correlation between personality scores and the reported frequency of visual disturbances. The study comprised 20 patients submitted to bilateral cataract surgery, 10 with a non-diffractive X-WAVE lens (AcrySof® IQ Vivity) and 10 with a trifocal lens (AcrySof® IQ PanOptix). Mean age was 60.23 (7.06) years. Six months following surgery, patients with lower scores of conscientiousness and extroversion reported a higher frequency of visual disturbances (blurred vision, P = .015 and P = .009, seeing double images P = .018 and P = .006, and having difficulties focusing, P = .027 and P = .022, respectively). In addition, patients with high neuroticism scores had more difficulty focusing (P = .033). In this study, personality traits such as low conscientiousness and extroversion and high neuroticism significantly influenced QoV perception 6 months after bilateral multifocal lens implantation. Patients' personality questionnaires could be a useful preoperative assessment test to a mIOL.

Evaluation of the Efficacy of an Ecobiological Dermo-Cosmetic Product to Help Manage and Prevent Relapses of Eyelid Atopic Dermatitis.

Atopic dermatitis (AD) is a chronic relapsing, inflammatory disease which causes eczematous lesions. Itching and symptoms visibility can have a significant impact on quality of life. This is the case when eyelids are affected. Therefore, we evaluated a dermo-cosmetic product designed to care AD on eyelids. An initial analysis of the product included 20 healthy women with no AD signs. A clinical evaluation of the effect of the product on AD sign severity was performed on 33 subjects presenting AD symptoms on eyelids. We also analyzed the product's capacity to prevent relapses in a parallel group clinical evaluation performed on 66 subjects. First, on the forearm skin of healthy subjects, the product reduces erythema and decreases transepidermal water loss when used for 28 days. Second, when clinically evaluated on subjects with eyelid symptoms undergoing a corticoid treatment, the product leads to reduced AD signs scored by a dermatologist, better self-evaluation of symptoms by subjects, and improved quality of life. Besides, upon assessment in a randomized controlled clinical evaluation with subjects prone to AD relapses but without symptoms, the product also drastically reduces relapse frequency. If erythema reduction is the only sign identified by a dermatologist, the product greatly and rapidly improves the quality of life of subjects. These effects can be explained by the known actions of the product's ingredients. Rich in hydrating compounds, fatty acids and anti-inflammatory compounds, it aims at maintaining and restoring the epidermis structure and function to preserve it from irritants. It effectively shows that a daily care and hygiene routine with a dermo-cosmetic product designed according to an ecobiological approach leads to objective improvement of AD and subjective perception of quality of life.

Saliency-Enabled Coding Unit Partitioning and Quantization Control for Versatile Video Coding

The latest video coding standard, versatile video coding (VVC), has greatly improved coding efficiency over its predecessor standard high efficiency video coding (HEVC), but at the expense of sharply increased complexity. In the context of perceptual video coding (PVC), the visual saliency model that utilizes the characteristics of the human visual system to improve coding efficiency has become a reliable method due to advances in computer performance and visual algorithms. In this paper, a novel VVC optimization scheme compliant PVC framework is proposed, which consists of fast coding unit (CU) partition algorithm and quantization control algorithm. Firstly, based on the visual saliency model, we proposed a fast CU division scheme, including the redetermination of the CU division depth by calculating Scharr operator and variance, as well as the executive decision for intra sub-partitions (ISP), to reduce the coding complexity. Secondly, a quantization control algorithm is proposed by adjusting the quantization parameter based on multi-level classification of saliency values at the CU level to reduce the bitrate. In comparison with the reference model, experimental results indicate that the proposed method can reduce about 47.19% computational complexity and achieve a bitrate saving of 3.68% on average. Meanwhile, the proposed algorithm has reasonable peak signal-to-noise ratio losses and nearly the same subjective perceptual quality.

The influence of social skills on the subjective perception of quality of life

Annotation. This article reflects a brief review of the content of the concepts of quality of life and social skills from the perspective of local authors and from the perspective of foreign literature. We will also present the results of the research on the influence of social skills on the subjective perception of quality of life, conducted in three universities in the Republic of Moldova.

Multitopic underwater image quality assessment with visual attention factors

Statistical information on underwater images related to subjective quality perception differs based on the environment. We initially propose whitish, yellowish, greenish, bluish topics for underwater images obtained by applying an integrated color distribution, that is, images under the same topic have the same hue. Inspired by the local multiscale, multidirectional statistical characteristics of the structure, contrast, and color of underwater images, we constructed visual attention factor sets for the above four typical underwater environment topics. Furthermore, a multitopic underwater image quality evaluation (MTUIQE) model is proposed to measure mix distortions in different underwater images. The method of measuring image quality based on image topic is proven to be more effective than directly fitting all the natural scene statistics features to the mean opinion scores. Experiments were conducted to show that the proposed MTUIQE approach is superior to existing objective underwater image quality evaluation methods. Compared with six commonly used blind image quality evaluation methods, the Pearson linear correlation coefficient and Spearman rank-order correlation coefficient are increased by more than 10%, which means that the quality assessment model adapted to specific degradation topics is more consistent with subjective underwater image quality perception, and it can effectively evaluate the performance of underwater image enhancement and restoration methods.

Confusing Image Quality Assessment: Toward Better Augmented Reality Experience.

With the development of multimedia technology, Augmented Reality (AR) has become a promising next-generation mobile platform. The primary value of AR is to promote the fusion of digital contents and real-world environments, however, studies on how this fusion will influence the Quality of Experience (QoE) of these two components are lacking. To achieve better QoE of AR, whose two layers are influenced by each other, it is important to evaluate its perceptual quality first. In this paper, we consider AR technology as the superimposition of virtual scenes and real scenes, and introduce visual confusion as its basic theory. A more general problem is first proposed, which is evaluating the perceptual quality of superimposed images, i.e., confusing image quality assessment. A ConFusing Image Quality Assessment (CFIQA) database is established, which includes 600 reference images and 300 distorted images generated by mixing reference images in pairs. Then a subjective quality perception experiment is conducted towards attaining a better understanding of how humans perceive the confusing images. Based on the CFIQA database, several benchmark models and a specifically designed CFIQA model are proposed for solving this problem. Experimental results show that the proposed CFIQA model achieves state-of-the-art performance compared to other benchmark models. Moreover, an extended ARIQA study is further conducted based on the CFIQA study. We establish an ARIQA database to better simulate the real AR application scenarios, which contains 20 AR reference images, 20 background (BG) reference images, and 560 distorted images generated from AR and BG references, as well as the correspondingly collected subjective quality ratings. Three types of full-reference (FR) IQA benchmark variants are designed to study whether we should consider the visual confusion when designing corresponding IQA algorithms. An ARIQA metric is finally proposed for better evaluating the perceptual quality of AR images. Experimental results demonstrate the good generalization ability of the CFIQA model and the state-of-the-art performance of the ARIQA model. The databases, benchmark models, and proposed metrics are available at: https://github.com/DuanHuiyu/ARIQA.

Viewport Rendering Algorithm with a Curved Surface for a Wide FOV in 360° Images

Omnidirectional visual content has attracted the attention of customers in a variety of applications because it provides viewers with a realistic experience. Among the techniques that are used to construct omnidirectional media, a viewport rendering technique is one of the most important modules. That is because users can perceptually evaluate the quality of the omnidirectional service based on the quality of the viewport picture. To increase the perceptual quality of an omnidirectional service, we propose an efficient algorithm to render the viewport. In this study, we analyzed the distortions in the viewport picture to be the result of sampling. This is because the image data for the unit sphere in the omnidirectional visual system are non-uniformly sampled to provide the viewport picture in the conventional algorithms. We propose an advanced algorithm to construct the viewport picture, in which the viewport plane is constructed using a curved surface, whereas conventional methods use flat square surfaces. The curved surface makes the sampling interval more equally spaced than conventional techniques. The simulation results show that the proposed technique outperforms the conventional algorithms with respect to the objective quality based on the criteria of straightness, conformality, and subjective perceptual quality.

P221 Quality of life in adult and children with cystic fibrosis during the COVID-19 pandemic in Croatia

Objectives: The aim of this study is to examine the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on quality of life among cystic fibrosis (CF) patients in Croatia. Methods: The study was conducted on a sample of 30 adults patients older than 19 years (17/30 female) and 42 paediatric patients with cystic fibrosis, from preschool children to 18 years (25/42 female). The patients were recruited from our CF Centre. Patients answered 15 short questions regarding their subjective perception of quality of life during the second wave of the SARS-CoV-2 pandemic in Croatia. Results: None of the patients answered they were positive to SARS-CoV-2 during the second wave of the pandemic. Half of adult CF patients were concerned about the virus, but only one (3.3%) neglected a control visit to the doctor. 18/30 of adult were less active during the pandemic. 5/30 (16.7%) had more frequent exacerbations of the disease. Around one quarter (26.7%) lost weight, while half gained weight. Half of adult CF patients feel that their quality of life is significantly impaired during this pandemic. In paediatric patients, almost half of the questionnaires were answered by parents or guardians. In CF children (N = 42), about three quarters were concerned about the virus and one fifth neglected control. Three fifths of children were less active, and 2/42 had more frequent exacerbations. Weight loss was recorded in 5/42 (12%), and more than half gained weight. Half of paediatric patients have a poorer quality of life than before the pandemic. Conclusion: In our survey, we have shown both adults and children were less active and had more frequent CF exacerbations and a substantial number of them lost weight. To conclude, the overall quality of life in adults and children with cystic fibrosis was significantly impaired.

To study the efficacy of zolpidem in inducing daytime sleep and maintaining mental alertness subsequent to awakening

Introduction: In operational environment, naps in the daytime could help in maintaining alertness and hence performance. However, due to operational constraints and circadian effect, an aircrew may not get good quantity and quality sleep during the day, even though adequate sleep window is available. In such situations, zolpidem could be effectively utilized to induce sleep. This study intended to examine the beneficial effects of zolpidem 5 mg and 10 mg in inducing daytime sleep and maintaining mental alertness in the subsequent awake period. Material and Methods: In a double-blind, placebo-controlled, repetitive measure design, 20 healthy male volunteers were longitudinally evaluated for their mental alertness and subjective perception of quality of sleep, sleepiness, and fatigue for a period of 12 h following zolpidem-induced daytime sleep. In addition, feedback was obtained on known untoward effects of zolpidem. Results: Zolpidem, in doses of both 5 mg and 10 mg, could induce daytime sleep in all participants. Quality of sleep induced by zolpidem was similar to that of night sleep quality. With 5 mg zolpidem, the alertness was maintained soon after awake from daytime sleep, whereas participants perceived sleepiness for a period of 1–2 h with 10 mg zolpidem. Following awakening, there was a significant increase in the number of lapses with time in the placebo group, which was not found significant with administration of zolpidem. The occurrence of untoward effects with 10 mg zolpidem was more than 5 mg zolpidem. Conclusion: Zolpidem 5 mg and 10 mg were found to be effective in inducing daytime sleep and maintaining performance subsequent to arousal. The sleepiness following arousal as well as adverse effects was found to be more for zolpidem 10 mg as compared to 5 mg. A mandatory ground observation of minimum of 8 h should be ensured following intake of zolpidem before undertaking any flying duties.

Effectiveness of Expressive Writing in the Reduction of Psychological Distress During the COVID-19 Pandemic: A Randomized Controlled Trial.

ObjectiveDue to the wide impact of the COVID-19 pandemic on mental health, the need for scalable interventions that can effectively reduce psychological distress has been recognized. Expressive writing (EW) can be beneficial for different conditions, including depression, suicidal ideation, and coping with trauma. Therefore, we aim to assess the applicability and effectiveness of an online format of EW in the reduction of psychological distress in context of the COVID-19 pandemic.MethodsIn this parallel-group, randomized controlled trial, participants (n = 120) were randomly allocated to (1) the intervention group-who completed five EW sessions over the 2 week period-or (2) the control group-who received treatment as usual (TAU). Participants were assessed for primary and secondary outcome measures at baseline, post-treatment, and follow-up-1-month after the treatment. The primary outcome was severity of psychological distress assessed at post-treatment, operationalized as Depression Anxiety Stress Scale (DASS) summary score. Secondary outcomes were severity of depression, anxiety, and stress (DASS subscale scores), well-being (WHO-5), subjective perception of quality of life (SQOL), and subjective evaluation of difficulties coping with pandemic, which were also assessed at post-treatment. Per protocol, analysis was conducted with available cases only.ResultsA less favorable outcome was found in the intervention group on psychological distress, and symptoms of stress, after controlling for baseline scores. Increased stress was recorded in the treatment group, with no effect in the control group. There was no significant difference between the groups on depression, anxiety, well-being, and subjective quality of life. No group effect for any of the outcomes measures was recorded at follow-up. Additional analysis revealed moderation effects of age and gender with older and male participants scoring higher on distress measures.ConclusionEngaging in EW during the pandemic was found to elevate stress; thus, when applied in the context of the COVID-19 pandemic, it may be harmful. Hence, EW or similar self-guided interventions should not be applied without prior evidence on their effects in the context of a pandemic and similar stressful and unpredictable circumstances.Clinical Trial RegistrationThis study is approved by the Institutional Ethics Committee (Protocol number #2020-20), and a trial has been registered at ISRCTN registry https://www.isrctn.com/ISRCTN17898730.

Subjective Perception of Life Quality Among Men with Physical Disabilities with Different Sport Participation Level

SummaryThe objective of the study was to analyse subjective perception of the quality of life (QOL) among men with physical disabilities with different sport participation level throughout quality of life indicators/domains satisfaction and overall QOL. Three groups of men with physical disabilities (n = 130) categorised by the level of sport participation were recruited for the study: elite athletes (n=26), recreational athletes (n = 45) and non-athletes (n = 59). The Subjective Quality of Life Analysis questionnaire and the WHOQOL User Manual were used as a primary research method. The highest subjective perception of life quality declares men elite athletes and the lowest non-athletes. Elite athletes are significantly more satisfied in their lives with domains Physical health/level of independence and Environment, indicators Sleep, Work, Leisure activities, Safety and overall QOL than non-athletes. No significant differences were found in subjective perception of life quality between men recreational athletes and non-athletes.

Quality Assessment of 3D Printed Surfaces Using Combined Metrics Based on Mutual Structural Similarity Approach Correlated with Subjective Aesthetic Evaluation

Quality assessment of the 3D printed surfaces is one of the crucial issues related to fast prototyping and manufacturing of individual parts and objects using the fused deposition modeling, especially in small series production. As some corrections of minor defects may be conducted during the printing process or just after the manufacturing, an automatic quality assessment of object’s surfaces is highly demanded, preferably well correlated with subjective quality perception, considering aesthetic aspects. On the other hand, the presence of some greater and more dense distortions may indicate a reduced mechanical strength. In such cases, the manufacturing process should be interrupted to save time, energy, and the filament. This paper focuses on the possibility of using some general-purpose full-reference image quality assessment methods for the quality assessment of the 3D printed surfaces. As the direct application of an individual (elementary) metric does not provide high correlation with the subjective perception of surface quality, some modifications of similarity-based methods have been proposed utilizing the calculation of the average mutual similarity, making it possible to use full-reference metrics without the perfect quality reference images, as well as the combination of individual metrics, leading to a significant increase of correlation with subjective scores calculated for a specially prepared dataset.

Visual function and subjective perception of vision after bilateral implantation of monofocal and multifocal IOLs: a randomized controlled trial.

To examine monocular and binocular visual function and patient-reported outcomes after implantation of multifocal IOLs (mIOLs) or monofocal IOLs, using a rigorous series of clinical assessments. BMI Southend Hospital, United Kingdom. Prospective, randomized, double-masked clinical trial. One hundred patients were randomized for bilateral implantation of either a Bi-Flex 677MY mIOL or a Bi-Flex 677AB IOL and were assessed at 3 to 6 months (V1) and 12 to 18 months (V2). Primary outcomes included distance, intermediate, and near logarithm of the minimum angle of resolution (logMAR) visual acuities (VAs) and defocus curve profile assessment. Secondary outcomes included reading speed, contrast sensitivity (CS), and the subjective perception of quality of vision. Forty-seven subjects with monofocal IOL and 43 mIOL subjects completed the study. Uncorrected (mIOL: 0.10 ± 0.09 logMAR; IOL: 0.09 ± 0.11 logMAR) and corrected (mIOL: 0.04 ± 0.06 logMAR; IOL: 0.01 ± 0.07 logMAR) distance VAs were comparable (P > .05). Uncorrected near VA (mIOL: 0.23 ± 0.13 logMAR; IOL: 0.55 ± 0.20 logMAR, P < .001) and distance-corrected near VA (mIOL: 0.24 ± 0.13 logMAR; IOL: 0.54 ± 0.17 logMAR, P < .001) were significantly improved with mIOLs. There was no significant difference in distance-corrected intermediate VA (mIOL: 0.38 ± 0.13 logMAR; IOL: 0.39 ± 0.13 logMAR, P = .431). Defocus curves demonstrated an increased range-of-focus among mIOLs (mIOL: 4.14 ± 1.10 diopter [D]; IOL: 2.57 ± 0.77 D). Pelli-Robson CS was different at V1 (P < .001) but similar by V2 (P = .059). Overall satisfaction was high (>90%) in both groups for distance tasks whereas significantly different for near tasks (mIOL, 18.45 ± 16.53 logUnits; IOL, 55.59 ± 22.52 logUnits). Uncorrected near visual acuity was demonstrably better with mIOLs and there was greater subjective satisfaction with quality of near vision. Halos reported by the mIOL group were significant compared with the IOL group but did not show an adverse effect on overall satisfaction.

P026 TOP GOALS AND CONCERNS REPORTED BY INDIVIDUALS WITH INFLAMMATORY BOWEL DISEASE AT OUTPATIENT GASTROENTEROLOGY CLINIC VISITS

Abstract Background The goals of managing inflammatory bowel disease (IBD) include eliminating disease symptoms, improving quality of life, and preventing disease progression/complications. In patients with chronic illnesses, their perception of the illness, emotional reactions, and concerns about the disease/treatment can influence self-management behaviors and their quality of life.[1] Studies of IBD patients’ self-reported disease concerns and subjective perceptions of quality of life are lacking. Here, we aim to understand IBD patients’ top concerns and goals using survey data collected within IBD Qorus, a nationwide Learning Health System for IBD with approximately 40 participating sites. Methods We conducted a qualitative content analysis on an open-ended question that was sent to IBD patients prior to their clinic visits with an IBD Qorus provider: “Currently, what is your number ONE concern or goal related to your IBD? This could be related to a specific symptom (e.g., diarrhea), worry for the future (e.g., need for surgery, cost of care) or how IBD might impact an upcoming life event (e.g., wedding, travel). Or you can report that you have no current concerns or goals.” Using the inductive approach, two independent researchers (who are not involved with direct clinical care of IBD Qorus patients) coded the responses into major and minor themes, which were then discussed with a third independent coder (an IBD Qorus provider). Each response received one or more codes (if multiple themes were mentioned). Results In the first 100 responses from a purposeful sample of six IBD Qorus sites (3 academic and 3 community sites in diverse rural and urban geographic locations), four domains of goals/concerns were identified: symptoms and goals for the symptoms (28/100), medication and their efficacy/side effects (28/100), IBD clinical course and management (29/100), and psychosocial effects of IBD (29/100) (Figure 1). The most common themes in each domain were: abdominal pain and fecal urgency (symptoms), biologics and side effects (medications), surgery and nutrition (IBD clinical course and management), and fear/worry and traveling (psychosocial effects) (Figure 1). Fives responses contained no concerns/goals and three were uncodeable. Conclusion IBD patients’ disease-related concerns and goals are broad and diverse, and our study suggests that they are evenly distributed between symptoms, medications, disease course, and psychosocial effects. Understanding patients’ perceptions about the disease and the types of information they desire can aid providers to create and achieve shared treatment goals. Reference