Lesions of the ventricular ependyma and its derivatives can be visualized by CT scans, and their nature and extent can be determined. Generalized enhancement of the ependyma following the administration of intravenous contrast media can be seen with spendymoma, medulloblastoma, metastatic dysgerminoma, glioblastoma multiforme, and ependymitis. Localized ependymal enhancement can often be identified in the presence of acute ventriculitis, vascular anomalies or malformations, cerebral infarctions with luxury perfusion, and vascular neoplasms.