AbstractDusty plasma diffusion was applied to model the plasma response to perturbations in dust density, which yields small‐scale irregularities in electron density that are responsible for Polar Mesosphere Summer Echos. Previous diffusion models treated aerosols either as fixed‐charge dust or as multiple‐charge‐state dust using chemical rate equations. The growth of aerosol particles was previously considered in the study of layered structures in mesospheric clouds, but it has not been incorporated into dust diffusion. In this paper, a multicomponent diffusion of a dusty plasma, consisting of electrons, ions, and charged aerosols, is developed, accounting for the growth of the aerosols. It is shown that, for typical parameters in polar mesopause region, the evolution of the density structures of the dusty plasma undergoes an initial charging process (approximately 100 s), then an ambipolar diffusion process on ion time scale (approximately hundreds of seconds), and the aerosol diffusion on dust time scale (>104 s). Furthermore, the growth of the aerosols retards the dust diffusion and causes the transition from anticorrelation to correlation between the electron and ion density perturbations (contrary to only anticorrelation or correlation as in the case without considering the growth). The growth also bends the density profiles from upward shifting to downward sedimentation. In addition, larger initial grain radius and the width of the initial perturbation result in slower diffusion. The diffusion is much faster at 88 km than at 82 km.