Thyroid disease is a health problem that is commonly encountered in society. Disorders of the thyroid gland can cause various serious health conditions. Laboratory tests play an important role in the diagnosis and management of thyroid disease. This study aims to describe various types of laboratory tests used to diagnose thyroid disease. This research uses a literature review method by analyzing data from various sources, such as scientific journals, textbooks and clinical guidelines. The data collection technique in this research is literature study. After the data is collected, the analysis is carried out through three stages such as filtering data, presenting data, and making conclusions. The research findings show that several types of laboratory tests that are usually carried out for thyroid disease are Thyroid Stimulating Hormone (TSH), Thyroid Hormone (T3 and T4), Thyroglobulin (Tg), and Thyroid antibodies. Thyroid laboratory examination is an important tool for diagnosing and monitoring thyroid disease. Interpretation of thyroid laboratory examination results must be carried out taking into account the patient's clinical factors.