Structural Conversion Research Articles

Liquid–liquid phase separation and conformational strains of α-Synuclein: implications for Parkinson’s disease pathogenesis

Parkinson’s disease (PD) and other synucleinopathies are characterized by the aggregation and deposition of alpha-synuclein (α-syn) in brain cells, forming insoluble inclusions such as Lewy bodies (LBs) and Lewy neurites (LNs). The aggregation of α-syn is a complex process involving the structural conversion from its native random coil to well-defined secondary structures rich in β-sheets, forming amyloid-like fibrils. Evidence suggests that intermediate species of α-syn aggregates formed during this conversion are responsible for cell death. However, the molecular events involved in α-syn aggregation and its relationship with disease onset and progression remain not fully elucidated. Additionally, the clinical and pathological heterogeneity observed in various synucleinopathies has been highlighted. Liquid–liquid phase separation (LLPS) and condensate formation have been proposed as alternative mechanisms that could underpin α-syn pathology and contribute to the heterogeneity seen in synucleinopathies. This review focuses on the role of the cellular environment in α-syn conformational rearrangement, which may lead to pathology and the existence of different α-syn conformational strains with varying toxicity patterns. The discussion will include cellular stress, abnormal LLPS formation, and the potential role of LLPS in α-syn pathology.

Pyrene-Functionalized Ru-Catenated Metallacycles: Conversion of Catenated System to Monorectangle through Aging.

Molecular transformation behavior within a mechanically interlocked system is often assisted by chemical manipulation, such as the inclusion of guest molecules, variation in the solution concentration, or swapping of solvents. We present in this report the synthesis of ruthenium metal and π-conjugated pyrene-based (2 + 2)2 catenated rectangles. Additionally, we discuss the structural conversion of these catenated rectangles into monorectangles through adjustments in concentration and solvent composition. In the presence of a methanol solution, a transformation into monorectangles was observed as the concentration declined. However, interestingly, in the presence of a nitromethane solution, an alteration in conformation to monorectangles was noted by just standing at room temperature for a few hours without any chemical manipulation. Furthermore, theoretical calculations were studied to provide insights into the formation of catenated structures over other potential ring-in-ring or Borromean-ring-type structures. The computational study with the GFN2-xTB method combined with density functional theory (DFT) calculations showed that the lower binding energy within the rectangles favors a catenated structure over other potential ring-in-ring or Borromean-ring-type structures. This work represents a new example of an intertwined structure that self-assembles into a catenated ring rather than a ring-in-ring or Borromean ring and transforms into a monorectangle in nitromethane without the use of any template, alteration in solution concentration, or exchange of solvents, but simply by standing at room temperature.

Modulation strategy design method for single-inductor multi-port converter based on reinforcement learning

Single-inductor multi-port converters have the characteristics of "more silicon and less magnetism" and have great application potential in many fields. However, single-inductor multi-port converters have many switching modes and the modulation strategy design is complex. The current design method is to manually select the switching mode sequence and perform modal analysis. The design process requires power electronics expertise and experience. This paper proposes a modulation strategy design method for single-inductor multi-port converters based on reinforcement learning. This method uses a neural network to generate the modulation strategy and adopts a set of simple rules to provide rewards for training the neural network. Through reinforcement learning, the neural network can summarize experience in trial and error without human intervention and finally generate the optimal modulation strategy. This method has many advantages: (1) It only requires known conditions such as port voltage and converter structure as input, and some simple constraints as rewards, avoiding complicated manual design; (2) It can use a neural network to generate the optimal modulation strategy under different operating conditions, and has strong adaptability. Based on this method, a modulation strategy design for a single-inductor multi-port converter is carried out, and the effectiveness of the method is verified by experiments.

Observation of Body‐Centered‐Cubic Cu Nanocluster with Partial Cu(0) Character

The structure of nanoparticles is a key determinant of their material properties. The synthesis of non‐face‐centered‐cubic (FCC) Cu nanoclusters (NCs) with Cu(0) character is still challenging due to their instability. Herein, a Cu(0)‐containing Cu NC is first reported to contain a metallic framework of 23 Cu atoms with a body‐centered‐cubic Cu@Cu8 core, stabilized by 6 triphenylphosphine (TPP) and 18 4‐methylbenzenethiolate ligands, as determined by single‐crystal X‐ray crystallography. The observed structure stands in stark contrast to the FCC and other structures reported for Cu NCs. Moreover, this newly formed NC could react with Au+ ion with controlled concentration, rapidly yielding another identifiable and bright red‐emitting AuCu14 cluster upon irradiation. Based on this structural conversion, a new “turn‐on” type of photoluminescent probe can be developed for the detection of Au+ ion with an ultrafast response time (30 s) at a low detection limit (0.13 ppm). This work provides a new way of understanding the growth of metal clusters and exploring their applications in luminescent sensors.

Compilation of Shape Operators on Sparse Arrays

We show how to build a compiler for a sparse array language that supports shape operators such as reshaping or concatenating arrays, in addition to compute operators. Existing sparse array programming systems implement generic shape operators for only some sparse data structures, reduce shape operators on other data structures to those, and do not support fusion. Our system compiles sparse array expressions to code that efficiently iterates over reshaped views of irregular sparse data structures, without needing to materialize temporary storage for intermediates. Our evaluation shows that our approach generates sparse array code competitive with popular sparse array libraries: our generated shape operators achieve geometric mean speed-ups of 1.66×–15.3× when compared to hand-written kernels in scipy.sparse and 1.67×–651× when compared to generic implementations in pydata/sparse. For operators that require data structure conversions in these libraries, our generated code achieves geometric mean speed-ups of 7.29×–13.0× when compared to scipy.sparse and 21.3×–511× when compared to pydata/sparse. Finally, our evaluation demonstrates that fusing shape and compute operators improves the performance of several expressions by geometric mean speed-ups of 1.22×–2.23×.

A novel interleaved BIFRED-Zeta with intelligent MPPT for PV applications

ABSTRACT The current energy perspective postulates profound presence of Renewable Energy Sources (RESs), resulting in need for optimal DC-DC converter design to assure efficient power conversion and minimise losses. By minimising energy losses and improving power quality, an optimal converter design helps ensure a stable and reliable power supply from RESs, which is essential for meeting the growing demand for clean energy. Therefore, this research introduces an innovative Interleaved BIFRED-Zeta converter configuration, designed to meet all criteria associated with an optimal converter design. The interleaved architecture of converter allows the reduction of current ripples and voltage stress along with the improvement of efficiency. Furthermore, the absence of transformer in converter structure enables it to be simple, cost effective and less bulky. The Interleaved Boost Integrated Flyback Rectifier Energy Storage DC-DC (BIFRED)-Zeta converter duty cycle is adjusted continuously using Cascaded Artificial Neural Network (ANN) Maximum Power Point Tracking (MPPT) to further maximise Photovoltaics (PV) system power output. The capability of suggested converter design is demonstrated by the results obtained using simulation and laboratory prototype implementation. Thereby, a peak efficiency of 97.6% is estimated to be achieved using suggested converter design.

Bactericidal and Antifouling Coatings with the "Killing-Repelling-Killing" Triple Function Based on Cationic Copolymers with Structure Conversion and Capsaicin Analogue Release.

The capsaicin analogue N-(4-hydroxy-3-methoxybenzyl) acrylamide (HMBA) was linked with polylauryl methacrylate-b-poly(2-(N,N-dimethylamino)ethyl methacrylate) (PLMA-b-PDMAEMA) via a quaternization reaction with 4-(acrylamidomethyl)-2-methoxyphenyl 2-chloroacetate (AAMPCA). The amphiphilic copolymers were capable of transforming its structure in response to the solvent change from aprotic to protic, which was verified by the 1H NMR spectrum. The resulting cationic copolymers underwent a hydrolysis process in water, yielding zwitterionic groups on surfaces. Meanwhile, the bactericidal reagent HMBA was released. It was proved that the hydrolysis rate of the copolymers accelerated with higher temperature, higher pH value, and higher hydrophilic block units. And the controllable, sustainable release of HMBA was achieved with copolymer-mediated hydrolysis. Protein-repellent and bactericidal tests on the surface of the coating proved that antifouling and bactericidal performances of the coating correlated to the structure conversion abilities of the corresponding copolymer. The dynamic monitoring of Escherichia coli adhesion in 3 h evidenced the antifouling and bactericidal process of copolymers with different block ratios and concentrations. The coating incorporated with 3% PLMA120-b-(PDMAEMA-AAMPCA)120 in polylactic acid base materials showed an adhesion ratio of E. coli less than 1% within 1 h, and the survival ratio of the adhered bacteria is <1%, suggesting its rapid speed and high efficiency in "bacterial repelling and killing". Also, the PLMA120-b-(PDMAEMA-AAMPCA)120 copolymer demonstrated enhanced bactericidal ability compared with the mixture of cationic poly(laruyl methacrylate)120-b-poly(carboxybetaine methacrylate ester)120 (PLMA120-b-PCBMAE120) and free HMBA. The lowest minimal inhibitory concentration was 0.078 mg/mL against Staphylococcus aureus and 0.312 mg/mL against E. coli, respectively.

Honeycomb shaped carbon dopped 1T-2H-MoS2 heterojunction counter electrode with high short current for dye sensitized solar cells

Recent years have witnessed energy crises in various regions and the utilization of new energy is crucial. Dye-sensitized solar cells (DSSCs) are the third generation of photovoltaic cells that are expected to be more cost-effective than other types of solar cells. In this work, we report the synthesis of 1T-2H-MoS2/honeycomb shaped carbon (HSC) heterojunction composite counter electrodes for DSSCs via adding porous carbon in the facile hydrothermal method. The effects of HSC on the morphology, structure, electrochemical and photoelectric conversion properties of the 1T-2H-MoS2/HSC composites were investigated systematically. Both the results of electrochemical and photoelectric measurement suggest the excellent performance of the reduction of I3- and the regeneration of dye. The whole cell assembled with the MoS2/HSC-5.0 counter electrode achieved a short current density 22.24 mA∙cm−2 and a power conversion efficiency (PCE) of 8.42 %, which is significantly higher than that of the pure MoS2 electrode (5.89 %) and Platinum electrode (6.76 %), implying the MoS2/HSC-5.0 composite is a promising candidate for counter electrodes catalyst of DSSCs.

An additively manufactured dual circularly polarized open‐ended waveguide antenna using outer ridges with wideband characteristic

AbstractThis paper presents a novel additively manufactured wideband dual circularly polarized (CP) open‐ended waveguide (OEW) antenna, which adopts a pair of wedge‐shaped outer ridges acting as a circular polarizer. Study found that compared to the con‐ ventional designs that employ internal polarization converting structures, such outer ridges are capable of achieving wider axial ratio bandwidth (ARBW) and better reflection coefficients. On each ridge, two rectangular slots are designed to suppress the higher order mode caused by the increased waveguide size, and further expanding the ARBW. The proposed antenna is fed by two differential ports. By switching the feeding ports, the CP states can be altered to either right‐handed CP (RHCP) or left‐handed CP (LHCP). In terms of configuration, the proposed antenna has a simple one‐piece structure and is fabricated by using dielec‐ tric 3‐D printing technology. To form the waveguide walls, its partial surfaces are coated by copper films through electroplat‐ ing. The proposed antenna features easy fabrication and light weight. Experimental results show that the proposed antenna has an impedance bandwidth of larger than 47.6% (8–13 GHz) with reflection coefficients lower than −15 dB, while the 3‐dB ARBW is 37.7% from 8.4 to 12.3 GHz.

A Cross-Border Biorisk Toolkit for Healthcare Professionals.

The COVID-19 pandemic posed significant challenges to public health, exposing first responders to high biosafety risks during medical assistance and containment efforts. The PANDEM-2 study aimed to address these critical biosafety issues by emphasising the importance of frequently updated, harmonised guidelines. This study reviewed scientific publications, lessons learned, and real-world experiences from the COVID-19 pandemic to identify biorisk gaps in three critical areas: (i) patient transportation and management, (ii) sample handling and testing, and (iii) data management and communication by laboratory staff. At the onset of the pandemic, first responders faced several challenges, including the rapid expansion of emergency medical services, conversion of non-medical structures, increased internal and cross-border transport of infected patients, frequent changes in biosafety protocols, and a shortage of personal protective equipment. In response, this study developed a versatile and easily adaptable toolkit, including biosafety guidance and recommendations linked to updated national and international online repositories. It establishes the groundwork for a minimum standard that can be tailored to various pandemic response scenarios, using monkeypox as a fictive test case. The toolkit enables rapid access to updated information via QR codes and mobile devices, improving biorisk response by providing an adaptable and standardised approach for caregivers involved in national and cross-border responses.

DEVELOPMENT OF DUAL-SWITCHES BRIDGELESS PFC TOTEM-POLE SEPIC CONVERTER FOR LED DRIVER APPLICATION

This paper presents a Dual-Switch Bridgeless Power Factor Correction (DSBPFC) Single Ended Primary Inductor Converter (SEPIC) with Totem-Pole circuit structure for LED Driver Application. The conventional Full-Bridge Rectifier (FBR) SEPIC converter has five diodes, four in the rectifier bridge and one in the SEPIC. In addition, the FBR SEPIC converter has several drawbacks, including low power factor (PF), high current harmonics (THDi), and high output voltage ripple, due to the combination of two operation circuits in a single converter structure. The proposed DSBPFC SEPIC converter with Totem-Pole method improves PF and reduces THDi and output voltage ripple compared to the conventional FBR SEPIC. Additionally, it only requires three diodes instead of five. The optimization parameter design minimizes the THDi and output voltage ripple. In addition, to improve the quality of the AC source, the inductors are designed to operate in DCM and CCM based on the ripple-balancing concept between input and output inductors. As to reduce output voltage ripple, a high capacitance of output capacitor is used. The simulation result of the THDi is 3.8% whereas the experimental result shows that the THDi is 23.5%; which can be attributed to the parasitic elements at the passive components. Furthermore, the experimental results of the output voltage ripple are 2 V with output capacitance of 3300 μF, compared to the output voltage ripple of 4.40 V for 470 μF. Therefore, the proposed converter's design is confirmed with an output power of approximately 14.4 W.

Influence of Rheological Modifications on Primary Network Chemical and Structural Cure Kinetics for an Interpenetrating Polymer Network Resin.

The development of non-contact in situ techniques for monitoring cure kinetics has the potential to greatly improve both resin formulation and processing. We have recently shown that low-frequency Raman spectroscopy is a viable method for assessing resin structural cure kinetics and complements the traditional chemical conversion determined from the fingerprint region of the spectrum. In this work, we further evaluate the relationship between structural and chemical conversion by investigating two chemically identical yet rheologically different interpenetrating polymer network resin formulations. Rheological analysis demonstrates a relationship between structural conversion and storage modulus, which is not observed in the chemical conversion data. We show that one can produce master cure kinetics curves with comparable kinetic constants using both the chemical and structural conversion methodologies. Parametric analysis of the structural conversion, chemical conversion, and photorheological conversion was combined with a semi-empirical model for the storage shear modulus as a function of the extent of cure.

Optimal‐droop voltage‐restorer for zonal dc distribution system with simultaneous consideration of dynamic current balance and power loss reduction

AbstractA dc voltage restorer (dc‐VR) with optimal droop control is developed to reduce the power loss and solve the dynamic current imbalance simultaneously of the zonal dc distribution system integrating multi‐parallel energy storage. Firstly, the power loss model composed of line loss and converter loss is built and it is proved to be a strictly convex function with respect to droop coefficients, which indicates the power loss can be mitigated by optimizing the current distribution. Thus, an image‐based droop optimization method is proposed to search for the optimal droop coefficients. Then, the economy of voltage compensation on power loss reduction is investigated and an ESS‐combined dc‐VR is designed, including an interleaved parallel architecture and a capacitor‐integrated electric spring (C‐ES). Unified virtual inertia is proposed for interleaved parallel bridge arms to make their dynamic performance consistent. And the newly introduced C‐ES can keep the bus voltage at the rated level to reduce the system cost. Therefore, the problem of dynamic currents imbalance is addressed from the points of converter structure (dc‐VR) and control system (unified inertia), and the power loss can be reduced by voltage recovery (C‐ES) and optimizing the current reallocation which is achieved by updating sharing coefficients from the image‐based droop optimization method. Finally, the simulation cases validate the effectiveness of the proposed optimal‐droop dc‐VR on dynamic current balance and power loss reduction, and hardware in the loop experiment results prove the consistent dynamic characteristics of the dc‐VR's arms.

Effectiveness of preventive intervention programmes aiming to improve oral health in children who have undergone caries-related dental extractions: a rapid review.

To determine the effectiveness of preventive interventions in children who have undergone caries-related dental extractions. Rapid review across five databases (CENTRAL, Ovid Medline, Embase, Web of Science and Scopus). Quality was assessed using the Risk of Bias 2 tool. Five studies were included, all randomised controlled trials involving pre-and/or post-extractions activity. Three studies involved oral health education (computer game, motivational interviewing, visual aids), one delivered clinical prevention (fissure sealants), and one an enhanced prevention programme combining additional health education and a clinical intervention (fluoride varnish). Retention was mixed (55%-80% in the intervention groups). Of the three studies measuring caries, all reported less caries development in the test group. However, only a study involving a dental nurse-delivered structured conversation, informed by motivational interviewing, showed an improvement in oral health. Two studies reporting on plaque and gingival bleeding had conflicting results. A study reporting on subsequent dental attendance did not demonstrate a clear improvement. Few published studies have explored prevention-based interventions in high caries-risk children requiring dental extractions. Whilst evidence of clinical benefit of preventive interventions in this population is limited, the potential use of contemporary behaviour change techniques appears promising. There is an urgent need for more high-quality longer-term trials using contemporary methodologies.

Development of Polarization-Insensitive THz-to-IR Converters for Low-IR-Signature Target Detection and Imaging.

A THz-to-IR converter can be an effective solution for the detection of low-IR-signature targets by combining the advantages of mature IR detection mechanisms with high atmospheric transmittance in the THz region. A metallic metasurface (MS)-based absorber with linear polarization dependence based on a split-ring resonator (SRR) unit cell has been previously studied as a preliminary example of a THz-to-IR converter structure in the literature. In this simulation-based study, a new cross-shaped unit cell-based metallic MS absorber structure sensitive to dual polarization is designed to eliminate linear polarization dependency, thereby allowing for incoherent detection of THz radiation. A model is developed to calculate the temperature difference and the response time for this new cross-shaped absorber structure, and its performance is compared to the SRR structure for both coherent and incoherent illumination. This model allows for understanding the efficiency of these structures by considering all loss mechanisms which previously had not been considered. It is found that both structures show similar performance under linearly polarized coherent illumination. However, under incoherent illumination, the IR emittance efficiency as gauged by the temperature difference for the cross-shaped structure is found to be twice as high as compared to the SRR structure. The results also imply that calculated temperature differences for both structures under coherent and incoherent illumination are well above the limit of the minimum resolvable temperature difference of the state-of-the-art IR cameras. Therefore, dual-polarized or multi-polarization-sensitive MS absorber structures can be crucial for developing cost-effective THz-to-IR converters and be implemented in THz imaging solutions.

Accelerated structural transformation of metal-organic frameworks via interfacial engineering for efficient oxygen evolution reaction

Most metal-organic frameworks (MOFs) undergo structural transformations during the oxygen evolution reaction (OER), prompting the development of more catalytically active metal oxyhydroxides. However, one of the biggest challenges still is managing the MOF reconstruction process. Here, we present an interface engineering strategy to encourage MOFs to structurally change into metal oxyhydroxides, which are more active in the OER process. By meticulous design, the NiSe/CoFc′ (CoFc-MOF, Fc′ = 1,1′-ferrocenecarboxylic acid) heterojunction was successfully constructed, exhibiting remarkable interface coupling effects. This characteristic not only facilitates efficient electron transfer from CoFc′ to NiSe, and accelerates the structural transformation process of CoFc′, but also activates more catalytic active sites. Compared to pure CoFc′, NiSe/CoFc′ exhibits enhanced structural transformation capability, occurring in a shorter time and at a lower voltage, with more catalytic sites being activated. Furthermore, the transformed NiSe/CoFc′ displays suprior catalytic activity with an overpotential of 227 mV at a current density of 100 mA cm−2, surpassing the single-component CoFc′. And the Faradaic efficiency of NiSe/CoFc′ is near to 99.6%. This approach offers a noval avenue for the levelheaded plan of non-precious metal electrocatalysts for water electrolysis, enabling the control of structural conversion through interface engineering.

Rotation insensitive implantable wireless power transfer system for medical devices using metamaterial-polarization converter

This article introduces an innovative approach for creating a circular polarization (CP) antenna-based rotation-insensitive implantable wireless power transfer (WPT) system for medical devices. The system is constructed to work in the industrial, scientific, and medical (ISM) frequency band of 902–928 MHz. Initially, a flexible, wide-band, and bio-compatible open-ended CP slot antenna is designed within a single-layer human skin tissue model to serve as the receiving (Rx) element. To form the implantable WPT link, a circular patch antenna is also constructed in the free-space to use as a transmitting (Tx) source. Further, a new metamaterial-polarization converter (MTM-PC) structure is developed and incorporated into the proposed system to enhance the power transfer efficiency (PTE). Furthermore, the rotational phenomenon of the Rx implant has been studied to show how the rotation affects the system’s performance. Moreover, a numerical analysis of the specific absorption rate (SAR) is conducted to confirm compliance with safety regulations and prioritize human safety from electromagnetic exposure. Finally, to validate the introduced concept, prototypes of the different elements of the proposed WPT system were fabricated and tested using skin-mimicking gel and porcine tissue. The measured results confirm the feasibility of the introduced approach, exhibiting improved efficiency due to use of the MTM-PC. The amplitude of the transmission coefficient (|S21|\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$|S_{21}|$$\\end{document}) has improved by 6.94 dB in the simulation, whereas the enhancement of 7.04 dB and 6.76 dB is obtained from the experimental study due to the integration of MTM-PC. As a result, the PTE of the proposed MTM-PC integrated implantable WPT system is increased significantly compared to the system without MTM-PC.

In Situ Photoreversible Tuning of Chemical Interface Damping in Single Gold Nanorods Through Cucurbit[8]uril-Based Host-Guest Interactions.

Chemical interface damping (CID) is a recently proposed plasmon-damping pathway based on the interfacial hot-electron transfer from metal to adsorbate molecules. However, the in situ reversible tuning of CID in single gold nanorods (AuNRs) has remained a considerable challenge. In this study, we used total internal reflection scattering microscopy and spectroscopy to investigate the CID induced by p-aminoazobenzene (p-AAB), which has fast photoisomerization characteristics, attached to single AuNRs. We demonstrated the in situ reversible tuning of CID in single AuNRs by switching between ultraviolet (UV, 365 nm) and visible (vis, 465 nm) irradiation to induce photoresponsive structural conversions between the cis and trans forms of p-AAB in ethanol, leading to different lowest unoccupied molecular orbital (LUMO) energies for both forms. The localized surface plasmon resonance (LSPR) line width was wide under vis irradiation but narrow under UV irradiation, indicating that hot electrons are more efficiently transferred to trans-p-AAB with a low LUMO energy level. We further investigated the in situ photoreversible tuning of CID by manipulating supramolecular host-guest interactions between cucurbit[8]uril (CB[8]) and p-AAB in the single AuNRs. Additionally, real-time in situ reversible tuning of CID in single AuNRs was achieved through photonic switching of the cis-trans forms of p-AAB inside CB[8]. The LSPR line width was narrow under vis irradiation but gradually widened under UV irradiation before narrowing again upon returning to vis irradiation, unlike the case with p-AAB only. These results can be ascribed to the fact that cis-p-AAB completely encapsulated within CB[8] in water is thermodynamically more favorable than trans-p-AAB. Therefore, we have discovered a new strategy for tuning the CID by performing p-AAB photoisomerization and adjusting the wavelength of incident light in single AuNRs. In addition, this study demonstrates that CID can be effectively applied to the development of biosensors to detect guest molecules and their structural changes inside the cavity of CB[8] in single AuNRs.

Unraveling the impact of pore length on the conversion reaction of Fe3O4/carbon anodes in lithium-ion batteries

Despite numerous studies investigating Fe3O4/porous carbon anode materials for high-performance lithium-ion batteries (LIBs), the inherent limitations of the Fe3O4 conversion reaction, such as low reversibility and sluggish kinetics, continue to pose significant challenges. While modifying the porous structure of Fe3O4 anodes has demonstrated considerable promise in overcoming these limitations, the precise relationship between the porous structure and Fe3O4 conversion behavior still remains unclear. Here, we explore the impact of the pore length of the anode active material on the electrochemical performance of LIBs. Using two different composites of Fe3O4 and porous carbon with varying pore lengths as model materials, we conduct various in-depth electrochemical and ex-situ analyses. Our findings confirm that a shorter pore length facilitates higher Li+ ion diffusivity compared to longer pore length. Consequently, the conversion reaction of Fe3O4 to Fe and Li2O during lithiation process can be expedited, leading to a decrease in the resistance at the solid electrolyte interphase. As a result, we demonstrate that shortening the pore length of the porous anode composite materials can enhance the initial Coulombic efficiency (CE), reversible capacity, and rate capability of LIBs.

Portable smartphone-assisted amperometric immunosensor based on CoCe-layered double hydroxide for rapidly immunosensing erythromycin

Herein, we have manufactured a newly designed bifunctional impedimetric and amperometric immunosensor for rapidly detecting erythromycin (ERY) in complicated environments and food stuffs. For this, bimetallic cobalt/cerium-layered double hydroxide nanosheets (CoCe-LDH NSs), which was derived from Co-based zeolite imidazole framework via the structure conversion, was simultaneously utilized as the bioplatform for anchoring the ERY-targeted antibody and for modifying the gold and screen printed electrode. Basic characterizations revealed that CoCe-LDH NSs was composed of mixed metal valences, enrich redox, and abundant oxygen vacancies, facilitating the adhesion on the electrode, the antibody adsorption, and the electron transfers. The manufactured impedimetric and amperometric immunosensor based on CoCe-LDH has showed the comparable sensing performance, having a wide linear detection range from 1.0 fg mL−1 to 1.0 ng mL−1 with the ultralow detection limit toward ERY. Also, the portable, visualized, and efficient analysis of ERY was then attained at the smartphone-assisted CoCe-LDH-based SPE.