The southern part of Tyrrhenian back-arc basin (NW Sicily), formed due to the rifting and spreading processes in back-arc setting, is currently undergoing contractional tectonics. The analysis of seismic reflection profiles integrated with bathymetry, magnetic data and seismicity allowed us to map a widespread contractional tectonics structures, such as positive flower structures, anticlines and inverted normal faults, which deform the sedimentary sequence of the intra-slope basins. Two main tectonic phases have been recognised: (i) a Pliocene extensional phase, active during the opening of the Vavilov Basin, which was responsible for the formation of elongated basins bounded by faulted continental blocks and controlled by the tear of subducting lithosphere; (ii) a contractional phase related to the Africa-Eurasia convergence coeval with the opening of the Marsili Basin during the Quaternary time. The lithospheric tear occurred along the Drepano paleo-STEP (Subduction-Transform-Edge-Propagator) fault, where the upwelling of mantle, intruding the continental crust, formed a ridge. Since Pliocene, most of the contractional deformation has been focused along this ridge, becoming a good candidate for a future subduction initiation zone.