From the point of view of a clinical integrative approach, psychopathological and typological clarification of the forms of anxiety that occur during major depression is undertaken. First, we examine "pure restriction", expressed by anxiety accompanied by a feeling of lack of feeling. Secondly, we distinguish this from a continuous or attack-like anxiety occuring within a socalled "destabilized restriction" (Janzarik). Finally, anxiety can be an expression of "forced restriction" characterized by developing tension between repression of feelings and emotions on the one hand and overloading of judgmental thought patterns on the other. We describe the appropriate structural and dynamic presuppositions of depressive anxiety syndromes and present a practical guideline for clinical therapy in its functional and personal aspects, developed as a result of our approach.